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BSR and BHPR guideline for the management of adults with ANCA-associated vasculitis. Rheumatology (Oxford) 53: 2306-2309, 2014.","DOI":"10.1093\/rheumatology\/ket445"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Pagnoux C, Mahr A, Hamidou MA, et al. Azathioprine or methotrexate maintenance for ANCA-associated vasculitis. N Engl J Med 359: 2790-2803, 2008.","DOI":"10.1056\/NEJMoa0802311"},{"key":"6","unstructured":"6. Hiemstra TF, Walsh M, Mahr A, et al. Mycophenolate mofetil vs azathioprine for remission maintenance in antineutrophil cytoplasmic antibody-associated vasculitis: a randomized controlled trial. JAMA 304: 2381-2388, 2010."},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Guillevin L, Pagnoux C, Karras A, et al. Rituximab versus azathioprine for maintenance in ANCA-associated vasculitis. N Engl J Med 371: 1771-1780, 2014.","DOI":"10.1056\/NEJMoa1404231"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Jayne D, Rasmussen N, Andrassy K, et al. A randomized trial of maintenance therapy for vasculitis associated with antineutrophil cytoplasmic autoantibodies. N Engl J Med 349: 36-44, 2003.","DOI":"10.1056\/NEJMoa020286"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Odahara S, Uchiyama K, Kubota T, et al. A prospective study evaluating metabolic capacity of thiopurine and associated adverse reactions in Japanese patients with inflammatory bowel disease (IBD). PLoS One 10: e0137798, 2015.","DOI":"10.1371\/journal.pone.0137798"},{"key":"10","unstructured":"10. Qiu Y, Mao R, Zhang SH, et al. Safety profile of thiopurines in Crohn disease: analysis of 893 patient-years follow-up in a Southern China cohort. Medicine (Baltimore) 94: e1513, 2015."},{"key":"11","unstructured":"11. Chaparro M, Ordas I, Cabre E, et al. Safety of thiopurine therapy in inflammatory bowel disease: long-term follow-up study of 3931 patients. Inflamm Bowel Dis 19: 1404-1410, 2013."},{"key":"12","unstructured":"12. Yates CR, Krynetski EY, Loennechen T, et al. Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance. Ann Intern Med 126: 608-614, 1997."},{"key":"13","unstructured":"13. Emmungil H, Durusoy R, Kalfa M, et al. Plasma thiopurine S-methyltransferase levels and azathioprine-related adverse events in patients with Behcet's disease. Clin Exp Rheumatol 33: S40-S45, 2015."},{"key":"14","unstructured":"14. Sada KE, Yamamura M, Harigai M, et al. Different responses to treatment across classified diseases and severities in Japanese patients with microscopic polyangiitis and granulomatosis with polyangiitis: a nationwide prospective inception cohort study. Arthritis Res Ther 17: 305, 2015."},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Okada Y, Nakamura K, Kodama T, et al. Thiopurine methyltransferase genotype and phenotype status in Japanese patients with systemic lupus erythematosus. Biol Pharm Bull 28: 2117-2119, 2005.","DOI":"10.1248\/bpb.28.2117"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Watts R, Lane S, Hanslik T, et al. Development and validation of a consensus methodology for the classification of the ANCA-associated vasculitides and polyarteritis nodosa for epidemiological studies. Ann Rheum Dis 66: 222-227, 2007.","DOI":"10.1136\/ard.2006.054593"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Mukhtyar C, Lee R, Brown D, et al. Modification and validation of the Birmingham Vasculitis Activity Score (version 3). Ann Rheum Dis 68: 1827-1832, 2009.","DOI":"10.1136\/ard.2008.101279"},{"key":"18","unstructured":"18. Houssiau FA, D'Cruz D, Sangle S, et al. Azathioprine versus mycophenolate mofetil for long-term immunosuppression in lupus nephritis: results from the MAINTAIN Nephritis Trial. Ann Rheum Dis 69: 2083-2089, 2010."},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Contreras G, Pardo V, Leclercq B, et al. Sequential therapies for proliferative lupus nephritis. N Engl J Med 350: 971-980, 2004.","DOI":"10.1056\/NEJMoa031855"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Croyle L, Hoi A, Morand EF. Characteristics of azathioprine use and cessation in a longitudinal lupus cohort. Lupus Sci Med 2: e000105, 2015.","DOI":"10.1136\/lupus-2015-000105"},{"key":"21","unstructured":"21. Jun JB, Cho DY, Kang C, Bae SC. Thiopurine S-methyltransferase polymorphisms and the relationship between the mutant alleles and the adverse effects in systemic lupus erythematosus patients taking azathioprine. Clin Exp Rheumatol 23: 873-876, 2005."},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Griffiths B, Emery P, Ryan V, et al. 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