{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T23:18:32Z","timestamp":1790983112899,"version":"4.1.0"},"reference-count":16,"publisher":"Japanese Society of Internal Medicine","issue":"15","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2026,8,1]]},"DOI":"10.2169\/internalmedicine.5836-25","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T22:11:28Z","timestamp":1785535888000},"page":"2124-2129","source":"Crossref","is-referenced-by-count":1,"title":["Scleroderma Renal Crisis and Posterior Reversible Encephalopathy Syndrome Triggered by Non-steroidal Anti-inflammatory Drugs"],"prefix":"10.2169","volume":"65","author":[{"given":"Takaya","family":"Suzuki","sequence":"first","affiliation":[{"name":"Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mai","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Miyata","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takaaki","family":"Nawano","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukino","family":"Yokokawa","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soichiro","family":"Kon","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eri","family":"Matsuki","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayumi","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keita","family":"Kamei","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazunobu","family":"Ichikawa","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masafumi","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Penn H, Howie AJ, Kingdon EJ, et al. Scleroderma renal crisis: patient characteristics and long-term outcomes. QJM 100: 485-494, 2007.","DOI":"10.1093\/qjmed\/hcm052"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Cole A, Ong VH, Denton CP. Renal disease and systemic sclerosis: an update on scleroderma renal crisis. Clin Rev Allergy Immunol 64: 378-391, 2023.","DOI":"10.1007\/s12016-022-08945-x"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Gewirtz AN, Gao V, Parauda SC, Robbins MS. Posterior reversible encephalopathy syndrome. Curr Pain Headache Rep 25: 19, 2021.","DOI":"10.1007\/s11916-020-00932-1"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Ando Y, Ono Y, Sano A, Fujita N, Ono S. Posterior reversible encephalopathy syndrome: a review of the literature. Intern Med 61: 135-141, 2022.","DOI":"10.2169\/internalmedicine.7520-21"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Fa&apos;ak F, Al-Bahadili H, Shah N, Julka K. Posterior reversible encephalopathy syndrome induced by scleroderma renal crisis in a patient with undiagnosed scleroderma. J Clin Rheumatol 27: S825-S826, 2021.","DOI":"10.1097\/RHU.0000000000001435"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Chen CY, Hung SY, Lee YJ, Lin YC, Pai CC. Delayed onset of posterior reversible encephalopathy syndrome in a case of scleroderma renal crisis with maintenance hemodialysis: case report and literature review. Medicine 95: e5725, 2016.","DOI":"10.1097\/MD.0000000000005725"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Bartynski WS. Posterior reversible encephalopathy syndrome, part 2: controversies surrounding pathophysiology of vasogenic edema. AJNR Am J Neuroradiol 29: 1043-1049, 2008.","DOI":"10.3174\/ajnr.A0929"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Fischer M, Schmutzhard E. Posterior reversible encephalopathy syndrome. J Neurol 264: 1608-1616, 2017.","DOI":"10.1007\/s00415-016-8377-8"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Kong W, Wang Y, Wang H, Zhou Q, Chen J, Han F. Systemic sclerosis complicated with renal thrombotic microangiopathy: a case report and literature review. BMC Nephrol 23: 22, 2022.","DOI":"10.1186\/s12882-021-02639-w"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Sukumar S, L\u00e4mmle B, Cataland SR. Thrombotic thrombocytopenic purpura: pathophysiology, diagnosis, and management. J Clin Med 10: 536, 2021.","DOI":"10.3390\/jcm10030536"},{"key":"11","unstructured":"11. Nagamura N, Kin S. Scleroderma renal crisis during intravenous cyclophosphamide pulse therapy for complicated interstitial lung disease was successfully treated with angiotensin converting enzyme inhibitor and plasma exchange. Nagoya J Med Sci 78: 329-334, 2016."},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Noris M, Remuzzi G. Atypical hemolytic-uremic syndrome. N Engl J Med 361: 1676-1687, 2009.","DOI":"10.1056\/NEJMra0902814"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Steen VD, Medsger TA Jr. Case-control study of corticosteroids and other drugs that either precipitate or protect from the development of scleroderma renal crisis. Arthritis Rheum 41: 1613-1619, 1998.","DOI":"10.1002\/1529-0131(199809)41:9<1613::AID-ART11>3.0.CO;2-O"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Klomjit N, Ungprasert P. Acute kidney injury associated with non-steroidal anti-inflammatory drugs. Eur J Intern Med 101: 21-28, 2022.","DOI":"10.1016\/j.ejim.2022.05.003"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Gordon SM, Hughes JB, Nee R, et al. Systemic sclerosis medications and risk of scleroderma renal crisis. BMC Nephrol 20: 279, 2019.","DOI":"10.1186\/s12882-019-1467-y"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Kamgang Semeu P, Taghavi M, Geers C, Mouthon L, Barreto Gutierrez L, Stordeur P. Scleroderma renal crisis triggered by ibuprofen: insights on complement-directed therapy. J Scleroderma Relat Disord 8: NP6-NP8, 2023.","DOI":"10.1177\/23971983231163663"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/65\/15\/65_5836-25\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T04:13:41Z","timestamp":1785557621000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/65\/15\/65_5836-25\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,1]]},"references-count":16,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.5836-25","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,1]]},"article-number":"5836-25"}}