{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T17:42:49Z","timestamp":1783446169895,"version":"3.55.0"},"reference-count":16,"publisher":"Japanese Society of Internal Medicine","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2026,4,1]]},"DOI":"10.2169\/internalmedicine.5963-25","type":"journal-article","created":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T22:07:14Z","timestamp":1756937234000},"page":"959-965","source":"Crossref","is-referenced-by-count":1,"title":["Negative Association between the Occurrence of Esophageal Candidiasis and Reflux Esophagitis"],"prefix":"10.2169","volume":"65","author":[{"given":"Kyoichi","family":"Adachi","sequence":"first","affiliation":[{"name":"Health Center, Shimane Environment and Health Public Corporation, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiko","family":"Okimoto","sequence":"additional","affiliation":[{"name":"Health Center, Shimane Environment and Health Public Corporation, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Utae","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Health Center, Shimane Environment and Health Public Corporation, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko","family":"Matsubara","sequence":"additional","affiliation":[{"name":"Health Center, Shimane Environment and Health Public Corporation, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiko","family":"Oka","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine, Shimane University Faculty of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norihisa","family":"Ishimura","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine, Shimane University Faculty of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunji","family":"Ishihara","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine, Shimane University Faculty of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Mohamed AA, Lu XL, Mounmin FA. Diagnosis and treatment of esophageal candidiasis: current updates. Can J Gastroenterol Hepatol 2019: 3585136, 2019.","DOI":"10.1155\/2019\/3585136"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Ogiso H, Adachi S, Mabuchi M, et al. Risk factors for the development of esophageal candidiasis among patients in community hospital. Sci Rep 11: 20663, 2021.","DOI":"10.1038\/s41598-021-00132-w"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Korkut E, Bekta\u015f M, Alkan M, et al. Esophageal motility and 24-h pH profiles of patients with heterotopic gastric mucosa in the cervical esophagus. Eur J Intern Med 21: 21-24, 2010.","DOI":"10.1016\/j.ejim.2009.10.009"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. von Rahden BH, Stein HJ, Becker K, Liebermann-Meffert D, Siewert JR. Heterotopic gastric mucosa of the esophagus: literature-review and proposal of a clinicopathologic classification. Am J Gastroenterol 99: 543-551, 2004.","DOI":"10.1111\/j.1572-0241.2004.04082.x"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Kishimoto K, Shibagaki K, Nonomura S, et al. Heterotopic gastric mucosa in middle esophagus complicated with esophageal ulcers. Intern Med 61: 2735-2740, 2022.","DOI":"10.2169\/internalmedicine.8705-21"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Weickert U, Wolf A, Schr\u00f6der C, Autschbach F, Vollmer H. Frequency, histopathological findings, and clinical significance of cervical heterotopic gastric mucosa (gastric inlet patch): a prospective study in 300 patients. Dis Esophagus 24: 63-68, 2011.","DOI":"10.1111\/j.1442-2050.2010.01091.x"},{"key":"7","doi-asserted-by":"publisher","unstructured":"7. Lundell LR, Dent J, Bennett JR, et al. Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification. Gut 45: 172-180, 1999.","DOI":"10.1136\/gut.45.2.172"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Adachi K, Fujishiro H, Katsube T, et al. Predominant nocturnal acid reflux in patients with Los Angeles grade C and D reflux esophagitis. J Gastroenterol Hepatol 16: 1191-1196, 2001.","DOI":"10.1046\/j.1440-1746.2001.02617.x"},{"key":"9","doi-asserted-by":"publisher","unstructured":"9. Kodsi BE, Wickremesinghe C, Kozinn PJ, Iswara K, Goldberg PK. Candida esophagitis: a prospective study of 27 cases. Gastroenterology 71: 715-719, 1976.","DOI":"10.1016\/S0016-5085(76)80347-2"},{"key":"10","unstructured":"10. Takahashi A, Oyama T. Candida esophagitis. I to Cho (Stomach Intestine) 54: 1610-1613, 2019 (in Japanese)."},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Grande L, Lacima G, Ros E, et al. Deterioration of esophageal motility with age: a manometric study of 79 healthy subjects. Am J Gastroenterol 94: 1795-1801, 1999.","DOI":"10.1111\/j.1572-0241.1999.01208.x"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Helm JF, Dodds WJ, Pelc LR, Palmer DW, Hogan WJ, Teeter BC. Effect of esophageal emptying and saliva on clearance of acid from the esophagus. N Engl J Med 310: 284-288, 1984.","DOI":"10.1056\/NEJM198402023100503"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Vissink A, Spijkervet FK, Van Nieuw Amerongen A. Aging and saliva: a review of the literature. Spec Care Dentist 16: 95-103, 1996.","DOI":"10.1111\/j.1754-4505.1996.tb00842.x"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Sadighi Akha AA. Aging and the immune system: an overview. J Immunol Methods 463: 21-26, 2018.","DOI":"10.1016\/j.jim.2018.08.005"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. O'Keefe JH, Bybee KA, Lavie CJ. Alcohol and cardiovascular health: the razor-sharp double-edged sword. J Am Coll Cardiol 50: 1009-1014, 2007.","DOI":"10.1016\/j.jacc.2007.04.089"},{"key":"16","doi-asserted-by":"publisher","unstructured":"16. Ford PJ, Rich AM. Tobacco use and oral health. Addiction 116: 3531-3540, 2021.","DOI":"10.1111\/add.15513"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/65\/7\/65_5963-25\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T03:55:17Z","timestamp":1775274917000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/65\/7\/65_5963-25\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,1]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.5963-25","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,1]]},"article-number":"5963-25"}}