{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T06:49:51Z","timestamp":1769928591143,"version":"3.49.0"},"reference-count":34,"publisher":"Japanese Society of Internal Medicine","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2021,6,1]]},"DOI":"10.2169\/internalmedicine.6176-20","type":"journal-article","created":{"date-parts":[[2020,12,28]],"date-time":"2020-12-28T22:27:14Z","timestamp":1609194434000},"page":"1747-1752","source":"Crossref","is-referenced-by-count":8,"title":["Heerfordt's Syndrome Associated with Trigeminal Nerve Palsy and Reversed Halo Sign"],"prefix":"10.2169","volume":"60","author":[{"given":"Go","family":"Makimoto","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, National Hospital Organization Iwakuni Clinical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keita","family":"Kawakado","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, National Hospital Organization Iwakuni Clinical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masamoto","family":"Nakanishi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, National Hospital Organization Iwakuni Clinical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoki","family":"Tamura","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, National Hospital Organization Iwakuni Clinical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minori","family":"Noda","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, National Hospital Organization Iwakuni Clinical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoko","family":"Makimoto","sequence":"additional","affiliation":[{"name":"Department of Radiology, National Hospital Organization Iwakuni Clinical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yumiko","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Pathology, National Hospital Organization Iwakuni Clinical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoichi","family":"Kuyama","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, National Hospital Organization Iwakuni Clinical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Greenberg G, Anderson R, Sharpstone P, James DG. Enlargement of parotid gland due to sarcoidosis. Br Med J 2: 861-862, 1964.","DOI":"10.1136\/bmj.2.5413.861"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Darlington P, Tallstedt L, Padyukov L, et al. HLA-DRB1* alleles and symptoms associated with Heerfordt&apos;s syndrome in sarcoidosis. Eur Respir J 38: 1151-1157, 2011.","DOI":"10.1183\/09031936.00025011"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Heerfordt C. [About a &quot;Febris uveoparotidea subchronica&quot; located on the parotid gland and the uvea of the eye and often complicated with paresis cerebrospinal nerves]. Arch Ophthalmol 70: 254-273, 1909 (in German).","DOI":"10.1007\/BF02008817"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Bruins-Slot WJ, Foedblod J, Goslings J. [Besnier-Boeck (Schaumann) disease and uveo parotitis (Heerfordt)]. Acta Med Scand 94: 74-97, 1938 (in German).","DOI":"10.1111\/j.0954-6820.1938.tb13593.x"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Otani K, Noda K, Ukichi T, Kingetsu I, Kurosaka D. A case of abortive type of Heerfordt syndrome associated with paralysis of trigeminal nerve. Nihon Rinsho Meneki Gakkai Kaishi 36: 115-121, 2013 (in Japanese, Abstraet in English).","DOI":"10.2177\/jsci.36.115"},{"key":"6","doi-asserted-by":"publisher","unstructured":"6. Hansell DM, Bankier AA, MacMahon H, McLoud TC, M\u00fcller NL, Remy J. Fleischner Society: glossary of terms for thoracic imaging. Radiology 246: 697-722, 2008.","DOI":"10.1148\/radiol.2462070712"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Voloudaki AE, Bouros DE, Froudarakis ME, Datseris GE, Apostolaki EG, Gourtsoyiannis NC. Crescentic and ring-shaped opacities. CT features in two cases of bronchiolitis obliterans organizing pneumonia (BOOP). Acta Radiol 37: 889-892, 1996.","DOI":"10.3109\/02841859609175463"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Kim SJ, Lee KS, Ryu YH, et al. Reversed halo sign on high-resolution CT of cryptogenic organizing pneumonia: diagnostic implications. AJR Am J Roentgenol 180: 1251-1254, 2003.","DOI":"10.2214\/ajr.180.5.1801251"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Godoy MC, Viswanathan C, Marchiori E, et al. The reversed halo sign: update and differential diagnosis. Br J Radiol 85: 1226-1235, 2012.","DOI":"10.1259\/bjr\/54532316"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Morimoto T, Azuma A, Abe S, et al. Epidemiology of sarcoidosis in Japan. Eur Respir J 31: 372-379, 2008.","DOI":"10.1183\/09031936.00075307"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Kumazoe H, Matsunaga K, Nagata N, et al. &quot;Reversed halo sign&quot; of high-resolution computed tomography in pulmonary sarcoidosis. J Thorac Imaging 24: 66-68, 2009.","DOI":"10.1097\/RTI.0b013e318190476f"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Di Stefano F, Paganelli R, Verna N, Di Gioacchino M. Cardiac sarcoidosis presenting as Heerfordt&apos;s syndrome. Am J Med 112: 594-595, 2002.","DOI":"10.1016\/S0002-9343(02)01067-7"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Fischer T, Filimonow S, Petersein J, Zimmer C, Beyersdorff D, Guski H. Diagnosis of Heerfordt&apos;s syndrome by state-of-the-art ultrasound in combination with parotid biopsy: a case report. Eur Radiol 12: 134-137, 2002.","DOI":"10.1007\/s003300100879"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Blair MP, Rizen M. Heerfordt syndrome with internal ophthalmoplegia. Arch Ophthalmol 123: 1017, 2005.","DOI":"10.1001\/archopht.123.7.1017"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Sugawara Y, Sakayama K, Sada E, et al. Heerfordt syndrome initially presenting with subcutaneous mass lesions: usefulness of gallium-67 scans before and after treatment. Clin Nucl Med 30: 732-733, 2005.","DOI":"10.1097\/01.rlu.0000182264.76461.74"},{"key":"16","unstructured":"16. Tamme T, Leibur E, Kulla A. Sarcoidosis (Heerfordt syndrome): a case report. Stomatologija 9: 61-64, 2007."},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Ueda N, Satoh T, Yamamoto T, Yokozeki H. Nodular cystic fat necrosis in Heerfordt&apos;s syndrome. J Eur Acad Dermatol Venereol 21: 708-709, 2007.","DOI":"10.1111\/j.1468-3083.2006.02005.x"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Petropoulos IK, Zuber JP, Guex-Crosier Y. Heerfordt syndrome with unilateral facial nerve palsy: a rare presentation of sarcoidosis. Klin Monbl Augenheilkd 225: 453-456, 2008.","DOI":"10.1055\/s-2008-1027356"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Evanchan J, Barreiro TJ, Gemmel D. Uveitis, salivary gland swelling, and facial nerve palsy in a febrile woman. Jaapa 23: 48-50, 2010.","DOI":"10.1097\/01720610-201005000-00012"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Yagi T, Hattori H, Ohira M, et al. Progressive multifocal leukoencephalopathy developed in incomplete Heerfordt syndrome, a rare manifestation of sarcoidosis, without steroid therapy responding to cidofovir. Clin Neurol Neurosurg 112: 153-156, 2010.","DOI":"10.1016\/j.clineuro.2009.10.005"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Denny MC, Fotino AD. The Heerfordt-Waldenstr\u00f6m syndrome as an initial presentation of sarcoidosis. Proc (Bayl Univ Med Cent) 26: 390-392, 2013.","DOI":"10.1080\/08998280.2013.11929014"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Dua A, Manadan A. Images in clinical medicine. Heerfordt&apos;s syndrome, or uveoparotid fever. N Engl J Med 369: 458, 2013.","DOI":"10.1056\/NEJMicm1303454"},{"key":"23","unstructured":"23. Chappity P, Kumar R, Sahoo AK. Heerfordt&apos;s syndrome presenting with recurrent facial nerve palsy: case report and 10-year literature review. Sultan Qaboos Univ Med J 15: e124-e128, 2015."},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Fujiwara K, Furuta Y, Fukuda S. Two cases of Heerfordt&apos;s syndrome: a rare manifestation of sarcoidosis. Case Rep Otolaryngol 2016: 3642735, 2016.","DOI":"10.1155\/2016\/3642735"},{"key":"25","unstructured":"25. Makimoto G, Miyahara N, Yoshikawa M, et al. Heerfordt&apos;s syndrome associated with a high fever and elevation of TNF-\u03b1. Acta Med Okayama 70: 273-277, 2016."},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Srirangaramasamy J, Kathirvelu S. A rare case of Heerfordt&apos;s syndrome with bilateral facial palsy. Indian J Otolaryngol Head Neck Surg 71: 1027-1029, 2016.","DOI":"10.1007\/s12070-016-0964-6"},{"key":"27","unstructured":"27. Broggi G, Reggio E, Giuliano L, Palmucci S, Caltabiano R, Lanzafame S. Parotid gland involvement in Heerfordt syndrome: a case report. Pathologica 109: 418-420, 2017."},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Fraga RC, Kakizaki P, Valente NYS, Portocarrero LKL, Teixeira MFS, Senise PF. Do you know this syndrome? Heerfordt-Waldenstr\u00f6m syndrome. An Bras Dermatol 92: 571-572, 2017.","DOI":"10.1590\/abd1806-4841.20175211"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Malkani R, Karia R. Leprosy or sarcoidosis? A diagnostic dilemma! J Family Med Prim Care 7: 1106-1108, 2018.","DOI":"10.4103\/jfmpc.jfmpc_30_18"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Ramachandran V, Haidari W, Ahn C, Tull R, Jorizzo JL. Uveoparotid fever as a presentation of sarcoidosis. Proc (Bayl Univ Med Cent) 32: 616-618, 2019.","DOI":"10.1080\/08998280.2019.1624107"},{"key":"31","doi-asserted-by":"publisher","unstructured":"31. Marchiori E, Zanetti G, Escuissato DL, et al. Reversed halo sign: high-resolution CT scan findings in 79 patients. Chest 141: 1260-1266, 2012.","DOI":"10.1378\/chest.11-1050"},{"key":"32","unstructured":"32. Fujii M, Ida M, Enomoto N, et al. A case of sarcoidosis manifesting as annular opacities after multiple nodular shadows. Nihon Kokyuki Gakkai Zasshi 40: 970-974, 2002."},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Marchiori E, Zanetti G, Mano CM, Hochhegger B, Irion KL. The reversed halo sign: another atypical manifestation of sarcoidosis. Korean J Radiol 11: 251-252, 2010.","DOI":"10.3348\/kjr.2010.11.2.251"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34. Zhan X, Zhang L, Wang Z, Jin M, Liu M, Tong Z. Reversed halo sign: presents in different pulmonary diseases. PLoS One 10: e0128153, 2015.","DOI":"10.1371\/journal.pone.0128153"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/60\/11\/60_6176-20\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T11:21:17Z","timestamp":1697455277000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/60\/11\/60_6176-20\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,1]]},"references-count":34,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.6176-20","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,1]]}}}