{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:01:32Z","timestamp":1790395292225,"version":"4.1.0"},"reference-count":11,"publisher":"Japanese Society of Internal Medicine","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2026]]},"DOI":"10.2169\/internalmedicine.7143-26","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T22:12:05Z","timestamp":1790028725000},"source":"Crossref","is-referenced-by-count":0,"title":["Cronkhite-Canada Syndrome Associated with Primary Cutaneous Peripheral T-cell Lymphoma and Membranous Nephropathy: A Case Report"],"prefix":"10.2169","author":[{"given":"Kohei","family":"Kiso","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Shimoyama","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saki","family":"Okuda-Hiwatashi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taku","family":"Fujimura","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihide","family":"Asano","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Makino","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuhiro","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideya","family":"Iwaki","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Nagai","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeo","family":"Naito","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rintaro","family":"Moroi","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoichi","family":"Kakuta","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Masamune","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Watanabe C, Komoto S, Tomita K, et al. Endoscopic and clinical evaluation of treatment and prognosis of Cronkhite-Canada syndrome: a Japanese nationwide survey. J Gastroenterol 51: 327-336, 2016.","DOI":"10.1007\/s00535-015-1107-7"},{"key":"2","unstructured":"2. Sweetser S, Boardman LA. Cronkhite-Canada syndrome: an acquired condition of gastrointestinal polyposis and dermatologic abnormalities. Gastroenterol Hepatol (N Y) 8: 201-203, 2012."},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Onozato Y, Sasaki Y, Abe Y, et al. Cronkhite-Canada syndrome associated with gastric outlet obstruction and membranous nephropathy: a case report and review of the literature. Intern Med 59: 2871-2877, 2020.","DOI":"10.2169\/internalmedicine.5278-20"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Firth C, Harris LA, Smith ML, Thomas LF. A case report of Cronkhite-Canada syndrome complicated by membranous nephropathy. Case Rep Nephrol Dial 8: 261-267, 2018.","DOI":"10.1159\/000494714"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Nakanoh H, Tsuji K, Morimoto S, et al. A case of membranous nephropathy complicated by Cronkhite-Canada syndrome successfully treated with mizoribine. CEN Case Rep 14: 72-80, 2025.","DOI":"10.1007\/s13730-024-00908-9"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Sweetser S, Ahlquist DA, Osborn NK, et al. Clinicopathologic features and treatment outcomes in Cronkhite-Canada syndrome: support for autoimmunity. Dig Dis Sci 57: 496-502, 2012.","DOI":"10.1007\/s10620-011-1874-9"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Xu Q, Jin L, Ou C, et al. Efficacy and safety of azathioprine in patients with Cronkhite-Canada syndrome: a case series from Peking Union Medical College Hospital. BMC Pharmacol Toxicol 25, 2024.","DOI":"10.1186\/s40360-024-00825-8"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Fan RY, Wang XW, Xue LJ, et al. Cronkhite-Canada syndrome polyps infiltrated with IgG4-positive plasma cells. World J Clin Cases 4: 248-252, 2016.","DOI":"10.12998\/wjcc.v4.i8.248"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Wu ZY, Sang LX, Chang B. Cronkhite-Canada syndrome: from clinical features to treatment. Gastroenterol Rep (Oxf) 8: 333-342, 2020.","DOI":"10.1093\/gastro\/goaa058"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Ellin F, Landstr\u00f6m J, Jerkeman M, Relander T. Real-world data on prognostic factors and treatment in peripheral T-cell lymphomas: a study from the Swedish Lymphoma Registry. Blood 124: 1570-1577, 2014.","DOI":"10.1182\/blood-2014-04-573089"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Kotlyar DS, Lewis JD, Beaugerie L, et al. Risk of lymphoma in patients with inflammatory bowel disease treated with azathioprine and 6-mercaptopurine: a meta-analysis. Clin Gastroenterol Hepatol 13: 847-858, 2015.","DOI":"10.1016\/j.cgh.2014.05.015"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/advpub\/0\/advpub_7143-26\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T03:32:12Z","timestamp":1790393532000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/advpub\/0\/advpub_7143-26\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":11,"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.7143-26","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"7143-26"}}