{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T01:17:16Z","timestamp":1793236636685,"version":"4.5.0"},"reference-count":26,"publisher":"Japanese Society of Internal Medicine","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2022,8,15]]},"DOI":"10.2169\/internalmedicine.8253-21","type":"journal-article","created":{"date-parts":[[2022,1,31]],"date-time":"2022-01-31T22:08:12Z","timestamp":1643666892000},"page":"2441-2448","source":"Crossref","is-referenced-by-count":5,"title":["Parietal Cell Dysfunction: A Rare Cause of Gastric Neuroendocrine Neoplasm with Achlorhydria and Extreme Hypergastrinemia"],"prefix":"10.2169","volume":"61","author":[{"given":"Yasuaki","family":"Abe","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waku","family":"Hatta","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sho","family":"Asonuma","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, South Miyagi Medical Center, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyuki","family":"Koike","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroko","family":"Abe","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohei","family":"Ogata","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Saito","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyi","family":"Jin","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Kanno","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaname","family":"Uno","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Asano","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Imatani","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiyoshi","family":"Fujishima","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hironobu","family":"Sasano","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Masamune","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"publisher","unstructured":"1. Rindi G, Luinetti O, Cornaggia M, et al. Three subtypes of gastric argyrophil carcinoid and the gastric neuroendocrine carcinoma: a clinicopathologic study. Gastroenterology 104: 994-1006, 1993.","DOI":"10.1016\/0016-5085(93)90266-F"},{"key":"2","doi-asserted-by":"publisher","unstructured":"2. Delle Fave G, O'Toole D, Sundin A, et al. ENETS consensus guidelines update for gastroduodenal neuroendocrine neoplasms. Neuroendocrinology 103: 119-124, 2016.","DOI":"10.1159\/000443168"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Tahara T, Shibata T, Nakamura M, et al. Gastric mucosal pattern by using magnifying narrow-band imaging endoscopy clearly distinguishes histological and serological severity of chronic gastritis. Gastrointest Endosc 70: 246-253, 2009.","DOI":"10.1016\/j.gie.2008.11.046"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Bansal A, Ulusarac O, Mathur S, et al. Correlation between narrow band imaging and nonneoplastic gastric pathology: a pilot feasibility trial. Gastrointest Endosc 67: 210-216, 2008.","DOI":"10.1016\/j.gie.2007.06.009"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Iijima K, Ohara S, Sekine H, et al. A new endoscopic method of gastric acid secretory testing. Am J Gastroenterol 93: 2113-2118, 1998.","DOI":"10.1111\/j.1572-0241.1998.00603.x"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Hatta W, Iijima K, Koike T, et al. Endoscopic findings for predicting gastric acid secretion status. Dig Endosc 27: 582-589, 2015.","DOI":"10.1111\/den.12427"},{"key":"7","doi-asserted-by":"publisher","unstructured":"7. Kikuchi H, Fukuda S, Koike T, et al. Association of residual gastric acid secretion with persistent symptoms in gastroesophageal reflux disease patients receiving standard-dose proton pump inhibitor therapy. Esophagus 18: 380-387, 2021.","DOI":"10.1007\/s10388-020-00765-2"},{"key":"8","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1159\/000199786","volume":"41","author":"E Solcia","year":"1988","unstructured":"8. Solcia E, Bordi C, Creutzfeldt W, et al. Histopathological classification of nonantral gastric endocrine growths in man. Digestion 41: 185-200, 1988.","journal-title":"Digestion","ISSN":"https:\/\/id.crossref.org\/issn\/0012-2823","issn-type":"print"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Ishioka M, Hirasawa T, Kawachi H, et al. Enterochromaffin-like cell neuroendocrine tumor associated with parietal cell dysfunction. Gastrointest Endosc 90: 841-845 e1, 2019.","DOI":"10.1016\/j.gie.2019.06.029"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Modlin IM, Lye KD, Kidd M. A 50-year analysis of 562 gastric carcinoids: small tumor or larger problem? Am J Gastroenterol 99: 23-32, 2004.","DOI":"10.1046\/j.1572-0241.2003.04027.x"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Niederle MB, Hackl M, Kaserer K, et al. Gastroenteropancreatic neuroendocrine tumours: the current incidence and staging based on the WHO and European Neuroendocrine Tumour Society classification: an analysis based on prospectively collected parameters. Endocr Relat Cancer 17: 909-918, 2010.","DOI":"10.1677\/ERC-10-0152"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. O'Connor JM, Marmissolle F, Bestani C, et al. Observational study of patients with gastroenteropancreatic and bronchial neuroendocrine tumors in Argentina: results from the large database of a multidisciplinary group clinical multicenter study. Mol Clin Oncol 2: 673-684, 2014.","DOI":"10.3892\/mco.2014.332"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Ooi A, Ota M, Katsuda S, et al. An unusual case of multiple gastric carcinoids associated with diffuse endocrine cell hyperplasia and parietal cell hypertrophy. Endocr Pathol 6: 229-237, 1995.","DOI":"10.1007\/BF02739887"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Abraham SC, Carney JA, Ooi A, et al. Achlorhydria, parietal cell hyperplasia, and multiple gastric carcinoids: a new disorder. Am J Surg Pathol 29: 969-975, 2005.","DOI":"10.1097\/01.pas.0000163363.86099.9f"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Nakata K, Aishima S, Ichimiya H, et al. Unusual multiple gastric carcinoids with hypergastrinemia: report of a case. Surg Today 40: 267-271, 2010.","DOI":"10.1007\/s00595-009-4032-7"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Rahman MA, Karam SM. Gastric parietal cell vacuolation mimicking gastric carcinoma. Histopathology 63: 735-737, 2013.","DOI":"10.1111\/his.12217"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Lahner E, Norman GL, Severi C, et al. Reassessment of intrinsic factor and parietal cell autoantibodies in atrophic gastritis with respect to cobalamin deficiency. Am J Gastroenterol 104: 2071-2079, 2009.","DOI":"10.1038\/ajg.2009.231"},{"key":"18","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/S0016-5085(19)33241-X","volume":"63","author":"K Kimura","year":"1972","unstructured":"18. Kimura K. Chronological transition of the fundic-pyloric border determined by stepwise biopsy of the lesser and greater curvatures of the stomach. Gastroenterology 63: 584-592, 1972.","journal-title":"Gastroenterology","ISSN":"https:\/\/id.crossref.org\/issn\/0016-5085","issn-type":"print"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Tahara T, Shibata T, Nakamura M, et al. Gastric mucosal pattern by using magnifying narrow-band imaging endoscopy clearly distinguishes histological and serological severity of chronic gastritis. Gastrointest Endosc 70: 246-253, 2009.","DOI":"10.1016\/j.gie.2008.11.046"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Sato Y. Endoscopic diagnosis and management of type I neuroendocrine tumors. World J Gastrointest Endosc 7: 346-353, 2015.","DOI":"10.4253\/wjge.v7.i4.346"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Sato Y, Imamura H, Kaizaki Y, et al. Management and clinical outcomes of type I gastric carcinoid patients: retrospective, multicenter study in Japan. Dig Endosc 26: 377-384, 2014.","DOI":"10.1111\/den.12197"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Vanoli A, La Rosa S, Miceli E, et al. Prognostic evaluations tailored to specific gastric neuroendocrine neoplasms: analysis of 200 cases with extended follow-up. Neuroendocrinology 107: 114-126, 2018.","DOI":"10.1159\/000489902"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Berna MJ, Hoffmann KM, Serrano J, et al. Serum gastrin in Zollinger-Ellison syndrome: I. prospective study of fasting serum gastrin in 309 patients from the National Institutes of Health and comparison with 2229 cases from the literature. Medicine (Baltimore) 85: 295-330, 2006.","DOI":"10.1097\/01.md.0000236956.74128.76"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Kotera T, Oe K, Kushima R, et al. Multiple pseudopolyps presenting as reddish nodules are a characteristic endoscopic finding in patients with early-stage autoimmune gastritis. Intern Med 59: 2995-3000, 2020.","DOI":"10.2169\/internalmedicine.4637-20"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Ayaki M, Aoki R, Matsunaga T, et al. Endoscopic and upper gastrointestinal barium X-ray radiography images of early-stage autoimmune gastritis: a report of two cases. Intern Med 60: 1691-1696, 2021.","DOI":"10.2169\/internalmedicine.6328-20"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Kishino M, Yao K, Hashimoto H, et al. A case of early autoimmune gastritis with characteristic endoscopic findings. Clin J Gastroenterol 14: 718-724, 2021.","DOI":"10.1007\/s12328-021-01351-4"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/61\/16\/61_8253-21\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,20]],"date-time":"2022-08-20T03:17:06Z","timestamp":1660965426000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/61\/16\/61_8253-21\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,15]]},"references-count":26,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.8253-21","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,15]]},"article-number":"8253-21"}}