{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:45:22Z","timestamp":1787024722978,"version":"build-2736575974"},"reference-count":8,"publisher":"Japanese Society of Internal Medicine","issue":"13","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2022,7,1]]},"DOI":"10.2169\/internalmedicine.8540-21","type":"journal-article","created":{"date-parts":[[2021,12,3]],"date-time":"2021-12-03T17:10:11Z","timestamp":1638551411000},"page":"1983-1986","source":"Crossref","is-referenced-by-count":8,"title":["Vasospastic Angina: An Immune-related Adverse Event"],"prefix":"10.2169","volume":"61","author":[{"given":"Taku","family":"Kumamoto","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Kawano","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaya","family":"Kurobe","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryohei","family":"Akashi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsuyoshi","family":"Yonekura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Maemura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Postow MA, Sidlow R, Hellmann MD. Immune-related adverse events associated with immune checkpoint blockade. N Engl J Med 378: 158-168, 2018.","DOI":"10.1056\/NEJMra1703481"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Mahmood SS, Fradley MG, Cohen JV, et al. Myocarditis in patients treated with immune checkpoint inhibitors. J Am Coll Cardiol 71: 1755-1764, 2018.","DOI":"10.1016\/j.jacc.2018.02.037"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Cautela J, Rouby F, Salem JE, et al. Acute coronary syndrome with immune checkpoint inhibitors: a proof-of-concept case and pharmacovigilance analysis of a life-threatening adverse event. Can J Cardiol 36: 476-481, 2020.","DOI":"10.1016\/j.cjca.2019.11.035"},{"key":"4","doi-asserted-by":"publisher","unstructured":"4. Drobni ZD, Alvi RM, Taron J, et al. Association between immune checkpoint inhibitors with cardiovascular events and atherosclerotic plaque. Circulation 142: 2299-2311, 2020.","DOI":"10.1161\/CIRCULATIONAHA.120.049981"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Otsu K, Tajiri K, Sakai S, Ieda M. Vasospastic angina following immune checkpoint blockade. Eur Heart J 41: 1702, 2020.","DOI":"10.1093\/eurheartj\/ehz796"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Gotsman I, Grabie N, Dacosta R, Sukhova G, Sharpe A, Lichtman AH. Proatherogenic immune responses are regulated by the PD-1\/PD-L pathway in mice. J Clin Invest 117: 2974-2982, 2007.","DOI":"10.1172\/JCI31344"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Bu DX, Tarrio M, Maganto-Garcia E, et al. Impairment of the programmed cell death-1 pathway increases atherosclerotic lesion development and inflammation. Arterioscler Thromb Vasc Biol 31: 1100-1107, 2011.","DOI":"10.1161\/ATVBAHA.111.224709"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Zamorano JL, Lancellotti P, Rodriguez Mu\u00f1oz D, et al.; ESC Scientific Document Group. 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines: The Task Force for cancer treatments and cardiovascular toxicity of the European Society of Cardiology (ESC). Eur Heart J 37: 2768-2801, 2016.","DOI":"10.1093\/eurheartj\/ehw211"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/61\/13\/61_8540-21\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,2]],"date-time":"2022-07-02T00:25:19Z","timestamp":1656721519000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/61\/13\/61_8540-21\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,1]]},"references-count":8,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.8540-21","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,1]]},"article-number":"8540-21"}}