{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T02:42:32Z","timestamp":1761964952466},"reference-count":29,"publisher":"Japanese Society of Internal Medicine","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2018]]},"DOI":"10.2169\/internalmedicine.9167-17","type":"journal-article","created":{"date-parts":[[2017,12,20]],"date-time":"2017-12-20T17:20:09Z","timestamp":1513790409000},"page":"601-604","source":"Crossref","is-referenced-by-count":7,"title":["Myasthenia Gravis Complicated with Peripheral T-cell Lymphoma, Not Otherwise Specified (PTCL-NOS), Following Thymectomy and Longstanding Tacrolimus Therapy"],"prefix":"10.2169","volume":"57","author":[{"given":"Masahiro","family":"Ohara","sequence":"first","affiliation":[{"name":"Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kokoro","family":"Ozaki","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuya","family":"Ohkubo","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akane","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiyuki","family":"Numasawa","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Hematology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shohei","family":"Tomii","sequence":"additional","affiliation":[{"name":"Department of Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoru","family":"Ishibashi","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuo","family":"Sanjo","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takanori","family":"Yokota","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"962","reference":[{"key":"1","unstructured":"1. Romi F, Gilhus NE, Aarli JA. Myasthenia gravis: clinical, immunological and therapeutic advances. Acta Neurol Scand 111: 134-141, 2005."},{"key":"2","unstructured":"2. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. 4th Ed. Steven H, Swerdlow EC, Harris NL, et al., Eds. International Agency for Research on Cancer, Lyon, France, 2008."},{"key":"3","unstructured":"3. Cory RF, Rios C, Kaya K, et al. Composite lymphocyte-rich thymoma and peripheral T-cell lymphoma not otherwise specified: case report and literature review. Lab Med 43: 4-8, 2012."},{"key":"4","unstructured":"4. Azzi JR, Sayegh MH, Mallat SG. Calcineurin inhibitor: 40 years later, can't live without... J Immunol 191: 5785-5791, 2013."},{"key":"5","unstructured":"5. Dharnidharka VR, Sullivan EK, Stablein DM, Tejani AH, Harmon WE. North American Pediatric Renal Transplant Cooperative Study (NAPRTCS): Risk factors for posttransplant lymphoproliferative disorder (PTLD) in pediatric kidney transplantation: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS). Transplantation 71: 1065-1068, 2001."},{"key":"6","unstructured":"6. Younes BS, McDiarmid SV, Martin MG, et al. The effect of immunosuppression on posttransplant lymphoproliferative disease in pediatric liver transplant patients. Transplantation 70: 94-99, 2000."},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Ellis D, Jaffe R, Green M, et al. Epstein-Barr virus-related disorders in children undergoing renal transplantation with tacrolimus-based immunosuppression. Transplantation 68: 997-1003, 1999.","DOI":"10.1097\/00007890-199910150-00017"},{"key":"8","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1097\/00007890-199502270-00015","volume":"59","author":"KL Cox","year":"1995","unstructured":"8. Cox KL, Lawrence-Miyasaki LS, Garcia-Kennedy R, et al. An increased incidence of Epstein-Barr virus infection and lymphoproliferative disorder in young children on FK506 after liver transplantation. Transplantation 59: 524-529, 1995.","journal-title":"Transplantation","ISSN":"http:\/\/id.crossref.org\/issn\/0041-1337","issn-type":"print"},{"key":"9","unstructured":"9. Sekiguchi Y, Shimada A, Imai H, et al. Epstein-Barr virus-negative, CD5-positive diffuse large B-cell lymphoma developing after treatment with oral tacrolimus for mixed connective tissue disease: a case report and review of the literature. J Clin Exp Hematopathol 52: 211-228, 2012."},{"key":"10","unstructured":"10. Miseki T, Sugata H, Kubo Y, et al. A case in which RA was not exacerbated during rituximab treatment of BL that occurred during FK506 use. Nihon Gan Chiryo Gakkai Shi 45: 966, 2010 (in Japanese, Abstract in English)."},{"key":"11","unstructured":"11. Minami N, Fujiki N, Doi S, et al. A case of myasthenia gravis in which a variety of tumors developed during the clinical course. Neurol Therap 24: 360, 2007 (in Japanese, Abstract in English)."},{"key":"12","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1159\/000069946","volume":"206","author":"M Corazza","year":"2003","unstructured":"12. Corazza M, Zampino MR, Montanari A, et al. Primary cutaneous CD30+ large T-cell lymphoma in a patient with psoriasis treated with cyclosporine. Dermatology 206: 330-333, 2003.","journal-title":"Dermatology","ISSN":"http:\/\/id.crossref.org\/issn\/1018-8665","issn-type":"print"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Koo JY, Kadonaga JN, Wintroub BV, et al. The development of B-cell lymphoma in a patient with psoriasis treated with cyclosporine. J Am Acad Dermatol 26: 836-840, 1992.","DOI":"10.1016\/0190-9622(92)70117-X"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Zijlmans JM, Rijthoven AW, Kluin PM, et al. Epstein-Barr virus-associated lymphoma in a patient with rheumatoid arthritis treated with cyclosporine. N Engl J Med 326: 1363, 1992.","DOI":"10.1056\/NEJM199205143262014"},{"key":"15","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1159\/000095044","volume":"213","author":"F Mougel","year":"2006","unstructured":"15. Mougel F, Dalle S, Balme B, et al. Aggressive CD30 large cell lymphoma after cyclosporine given for putative atopic dermatitis. Dermatology 213: 239-241, 2006.","journal-title":"Dermatology","ISSN":"http:\/\/id.crossref.org\/issn\/1018-8665","issn-type":"print"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Ogata M, Kikuchi H, Ono K, et al. Spontaneous remission of Epstein-Barr virus-negative non-Hodgkin's lymphoma after withdrawal of cyclosporine in a patient with refractory anemia. Int J Hematol 79: 161-164, 2004.","DOI":"10.1532\/IJH97.03095"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Shibahara T, Miyazaki K, Sato D, et al. Rectal malignant lymphoma complicating ulcerative colitis treated with long-term cyclosporine A. J Gastroenterol Hepatol 21: 336-338, 2006.","DOI":"10.1111\/j.1440-1746.2006.03988.x"},{"key":"18","unstructured":"18. US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER). Elidel NDA 21-302 pharmacology review [Internet]. 2001 Nov. 6 [cited 2017 Feb. 1]; Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/nda\/2001\/21-302_ELIDEL_pharmr_P2.pdf"},{"key":"19","unstructured":"19. Pediatric Advisory Committee presentation from Barbara Hill, Division of Dermatologic and Dental Drug Products, FDA Center for Drug Evaluation and Research. Topical immunosuppressants (calcineurin inhibitors)-animal toxicology [Internet]. 2005 Feb. 15 [cited 2017 Feb. 1]; Available from: http:\/\/www.fda.gov\/ohrms\/dockets\/ac\/05\/slides\/2005-4089s2_01_06_Hill.ppt"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Naschitz JE, Rosner I. Musculoskeletal syndromes associated with malignancy (excluding hypertrophic osteoarthropathy). Curr Opin Rheumatol 20: 100-105, 2008.","DOI":"10.1097\/BOR.0b013e3282f1ecd4"},{"key":"21","unstructured":"21. Zintzaras E, Voulgarelis M, Moutsopoulos HM. The risk of lymphoma development in autoimmune diseases: a meta-analysis. Arch Intern Med 165: 2337-2344, 2005."},{"key":"22","unstructured":"22. Mackay IR, Rose NR. Autoimmunity and lymphoma: tribulations of B cells. Nat Immunol 2: 793-795, 2001."},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Levin N, Abramsky O, Lossos A, et al. Extrathymic malignancies in patients with myasthenia gravis. J Neurol Sci 237: 39-43, 2005.","DOI":"10.1016\/j.jns.2005.05.009"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Bowen JD, Kidd P. Myasthenia gravis associated with T helper cell lymphoma. Neurology 37: 1405-1408, 1987.","DOI":"10.1212\/WNL.37.8.1405"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Mortimer JE, Kidd P. Myasthenia gravis and lymphoblastic lymphoma antiacetylcholine receptor antibody as a tumor marker-a case report. Cancer Invest 7: 327-331, 1989.","DOI":"10.3109\/07357908909039858"},{"key":"26","unstructured":"26. Strauchen JA. Indolent T-lymphoblastic proliferation: report of a case with an 11-year history and association with myasthenia gravis. Am J Surg Pathol 25: 411-415, 2001."},{"key":"27","unstructured":"27. Uner AH, Abali H, Engin H, et al. Myasthenia gravis and lymphoblastic lymphoma involving the thymus: a rare association. Leuk Lymphoma 42: 527-531, 2001."},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Nishioka R, Nakajima S, Morimoto Y, et al. T-cell acute lymphoblastic leukemia with transient pure red cell aplasia associated with myasthenia gravis and invasive thymoma. Intern Med 34: 127-130, 1995.","DOI":"10.2169\/internalmedicine.34.127"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Owe JF, Daltveit AK, Gilhus NE. Does myasthenia gravis provide protection against cancer? Acta Neur Scand 113: 33-36, 2006.","DOI":"10.1111\/j.1600-0404.2006.00612.x"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/57\/4\/57_9167-17\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,8]],"date-time":"2019-10-08T06:21:20Z","timestamp":1570515680000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/57\/4\/57_9167-17\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.9167-17","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018]]}}}