{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T19:26:04Z","timestamp":1783797964535,"version":"3.55.0"},"reference-count":15,"publisher":"Japanese Society of Internal Medicine","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2023,4,1]]},"DOI":"10.2169\/internalmedicine.9366-22","type":"journal-article","created":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T22:10:22Z","timestamp":1661811022000},"page":"1073-1076","source":"Crossref","is-referenced-by-count":8,"title":["Copper Deficiency in Wilson's Disease with a Normal Zinc Value"],"prefix":"10.2169","volume":"62","author":[{"given":"Masayuki","family":"Ueda","sequence":"first","affiliation":[{"name":"Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuto","family":"Katsuse","sequence":"additional","affiliation":[{"name":"Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyuki","family":"Kakumoto","sequence":"additional","affiliation":[{"name":"Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Ishiura","sequence":"additional","affiliation":[{"name":"Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Mitsui","sequence":"additional","affiliation":[{"name":"Department of Molecular Neurology, Graduate School of Medicine, The University of Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsushi","family":"Toda","sequence":"additional","affiliation":[{"name":"Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Pfeiffer RF. Wilson's disease. Handb Clin Neurol 100: 681-709, 2011.","DOI":"10.1016\/B978-0-444-52014-2.00049-5"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Horvath J, Beris P, Giostra E, Martin PY, Burkhard PR. Zinc-induced copper deficiency in Wilson disease. J Neurol Neurosurg Psychiatry 81: 1409-1410, 2010.","DOI":"10.1136\/jnnp.2009.188896"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Foubert-Samier A, Kazadi A, Rouanet M, et al. Axonal sensory motor neuropathy in copper-deficient Wilson's disease. Muscle Nerve 40: 294-296, 2009.","DOI":"10.1002\/mus.21425"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Cortese A, Zangaglia R, Lozza A, Piccolo G, Pacchetti C. Copper deficiency in Wilson's disease: peripheral neuropathy and myelodysplastic syndrome complicating zinc treatment. Mov Disord 26: 1361-1362, 2011.","DOI":"10.1002\/mds.23520"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Dzie\u017cyc K, Litwin T, Soba\u0144ska A, Cz\u0142onkowska A. Symptomatic copper deficiency in three Wilson's disease patients treated with zinc sulphate. Neurol Neurochir Pol 48: 214-218, 2014.","DOI":"10.1016\/j.pjnns.2014.05.002"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Lozano J, Mu\u00f1oz Bertr\u00e1n E, Ortega Gonz\u00e1lez I, G\u00f3mez Esp\u00edn R, L\u00f3pez Esp\u00edn MI. Myelopathy secondary to copper deficiency as a complication of treatment of Wilson's disease. Gastroenterol Hepatol 35: 704-707, 2012.","DOI":"10.1016\/j.gastrohep.2012.03.008"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. da Silva-J\u00fanior FP, Machado AAC, Lucato LT, Can\u00e7ado ELR, Barbosa ER. Copper deficiency myeloneuropathy in a patient with Wilson disease. Neurology 76: 1673-1675, 2011.","DOI":"10.1212\/WNL.0b013e318219fac8"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Narayan SK, Kaveer N. CNS demyelination due to hypocupremia in Wilson's disease from overzealous treatment. Neurol India 54: 110-111, 2006.","DOI":"10.4103\/0028-3886.25146"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. van den Hamer CJA, Hoogeraad TU. Copper deficiency in Wilson's disease. Lancet 2: 442, 1989.","DOI":"10.1016\/S0140-6736(89)90612-0"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Teodoro T, Neutel D, Lobo P. Recovery after copper-deficiency myeloneuropathy in Wilson's disease. J Neurol 260: 1917-1918, 2013.","DOI":"10.1007\/s00415-013-6963-6"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Shimizu N, Fujiwara J, Ohnishi S, et al. Effects of long-term zinc treatment in Japanese patients with Wilson disease: efficacy, stability, and copper metabolism. Transl Res 156: 350-357, 2010.","DOI":"10.1016\/j.trsl.2010.08.007"},{"key":"12","unstructured":"12. Ministry of Health, Labour and Welfare. Dietary Reference Intakes for Japanese (2015) [Internet]. 2015 [cited 2022 Apr 21]. Available from: mhlw.go.jp\/file\/06-Seisakujouhou-10900000-Kenkoukyoku\/Full_DRIs2015.pdf"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Porter KG, Mcmaster D, Elmes ME, Love AH. An\u00e6mia and low serum-copper during zinc therapy. Lancet 310: 774, 1977.","DOI":"10.1016\/S0140-6736(77)90295-1"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Todd LM, Godber IM, Gunn IR. Iatrogenic copper deficiency causing anaemia and neutropenia. Ann Clin Biochem 41: 414-416, 2004.","DOI":"10.1258\/0004563041731556"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Van Caillie-Bertrand M, Degenhart HJ, Luijendijk I, Bouquet J, Sinaasappel M. Wilson's disease: assessment of D-penicillamine treatment. Arch Dis Child 60: 652-655, 1985.","DOI":"10.1136\/adc.60.7.652"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/62\/7\/62_9366-22\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T03:50:46Z","timestamp":1680321046000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/62\/7\/62_9366-22\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,1]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.9366-22","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,1]]},"article-number":"9366-22"}}