{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T19:33:24Z","timestamp":1648928004298},"reference-count":7,"publisher":"Japanese Society of Internal Medicine","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Jpn. Soc. Intern. Med.","J. Jpn. Soc. Intern. Med"],"published-print":{"date-parts":[[2013]]},"DOI":"10.2169\/naika.102.3211","type":"journal-article","created":{"date-parts":[[2014,12,9]],"date-time":"2014-12-09T23:27:47Z","timestamp":1418167667000},"page":"3211-3214","source":"Crossref","is-referenced-by-count":0,"title":["Mitochondrial Encephalo-myopathy with Lactic Acidosis and Stroke-like Episodes (MELAS) Diagnosed Incidentally by Asymptomatic Cardiomegaly"],"prefix":"10.2169","volume":"102","author":[{"given":"Yuki","family":"Nomura","sequence":"first","affiliation":[{"name":"Division of Neurology, Hyogo Prefectural Amagasaki Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanako","family":"Ishihara","sequence":"additional","affiliation":[{"name":"Division of Neurology, Hyogo Prefectural Amagasaki Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rei","family":"Fukuhara","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Hyogo Prefectural Amagasaki Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kosho","family":"Takasu","sequence":"additional","affiliation":[{"name":"Division of Pathology, Hyogo Prefectural Amagasaki Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ichizo","family":"Nishino","sequence":"additional","affiliation":[{"name":"Department of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukihiro","family":"Yoneda","sequence":"additional","affiliation":[{"name":"Division of Neurology, Hyogo Prefectural Amagasaki Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiji","family":"Ichikawa","sequence":"additional","affiliation":[{"name":"Division of Neurology, Hyogo Prefectural Amagasaki Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasufumi","family":"Kageyama","sequence":"additional","affiliation":[{"name":"Division of Neurology, Hyogo Prefectural Amagasaki Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1212\/WNL.43.5.1015","volume":"43","author":"AM Remes","year":"1993","unstructured":"1) Remes AM, et al: Adult-onset diabetes mellitus and neurosensory hearing loss in maternal relatives of MELAS patients in a family with the tRNA (Leu (UUR)) mutation. Neurology 43: 1015-1020, 1993.","journal-title":"Neurology","ISSN":"http:\/\/id.crossref.org\/issn\/0028-3878","issn-type":"print"},{"key":"2","doi-asserted-by":"publisher","unstructured":"2) Anan R, et al: Cardiac involvement in mitochondrial diseases; a study on 17 patients with documented mitochondrial DNA defects. Circulation 91: 955-961, 1995.","DOI":"10.1161\/01.CIR.91.4.955"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Okajima Y, et al: A follow up study of myocardial involvement in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS). Heart 80: 292-295, 1998.","DOI":"10.1136\/hrt.80.3.292"},{"key":"4","doi-asserted-by":"publisher","unstructured":"4) Malfatti E, et al: High risk of severe cardiac adverse events in patients with mitochondrial m.3243A>G mutation. Neurology 80: 100-105, 2013.","DOI":"10.1212\/WNL.0b013e31827b1a2f"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Odawara M, et al: Prevalence and clinical characterization of Japanese diabetes mellitus with an A-to-G mutation at nucleotide 3243 of the mitochondrial tRNA (Leu (UUR)) gene. J Clin Endocrinol Metab 80: 1290-1294, 1995.","DOI":"10.1210\/jcem.80.4.7714102"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Iwasaki N, et al: Prevalence of A-to-G mutation at nucleotide 3243 of the mitochondrial tRNA (Leu (UUR)) gene in Japanese patients with diabetes mellitus and end stage renal disease. J Hum Genet 46: 330-334, 2001.","DOI":"10.1007\/s100380170068"},{"key":"7","doi-asserted-by":"crossref","unstructured":"8) Koga Y, et al: Molecular pathology of MELAS and L-arginine effects. Biochim Biophys Acta 1820: 608-614, 2012.","DOI":"10.1016\/j.bbagen.2011.09.005"}],"container-title":["Nihon Naika Gakkai Zasshi"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/naika\/102\/12\/102_3211\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,19]],"date-time":"2021-05-19T16:59:12Z","timestamp":1621443552000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/naika\/102\/12\/102_3211\/_article\/-char\/ja\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":7,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.2169\/naika.102.3211","relation":{},"ISSN":["0021-5384","1883-2083"],"issn-type":[{"value":"0021-5384","type":"print"},{"value":"1883-2083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}