{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T20:33:54Z","timestamp":1786480434189,"version":"build-2736575974"},"reference-count":205,"publisher":"Bentham Science Publishers Ltd.","issue":"23","funder":[{"DOI":"10.13039\/501100007446","name":"Deanship of Scientific Research at King Khalid University","doi-asserted-by":"publisher","award":["RGP2\/78\/46"],"award-info":[{"award-number":["RGP2\/78\/46"]}],"id":[{"id":"10.13039\/501100007446","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["CPD"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec>\n<jats:title\/>\n<jats:p>Cardiovascular diseases (CVDs) remain a global health challenge, with hypertension emerging as a\nleading risk factor. Hypertension, characterized by elevated arterial blood pressure (BP), significantly increases\nthe risk of stroke and other CVDs. Despite advancements in antihypertensive medication, the effectiveness\nof hypertension treatment is often hindered by poor bioavailability and limited drug efficacy. In this quest,\nnanoparticles (NPs) offer a promising avenue for addressing the limitations associated with conventional antihypertensive\ndrugs in hypertension treatment. Among several NPs, solid lipid nanoparticles (SLNs) have\nemerged as a potential candidate, presenting a multifaceted approach to revolutionize drug delivery within this\ndomain. SLNs, characterized by a lipophilic matrix and stabilized by surfactants, offer scalability and compatibility\nwith biological systems compared to several polymer-based nanosystems. By encapsulating antihypertensive\ndrugs, SLNs enhance drug solubility and bioavailability and provide sustained release, thereby improving\ntreatment efficacy. In this context, this review provides an overview of the pathophysiology of hypertension\nand the role of SLNs in drug delivery. Various preparation techniques of SLNs are discussed, highlighting\ntheir versatility and potential in pharmaceutical applications. Furthermore, the role of SLNs in the management\nof hypertension is thoroughly examined, with a focus on enhancing the physicochemical properties of antihypertensive\ndrugs. Overall, SLNs represent a promising strategy for optimizing hypertension treatment by\naddressing the limitations of conventional drug delivery systems. By enhancing drug stability, bioavailability,\nand efficacy, SLNs offer new possibilities for improving patient outcomes and reducing the global burden of\ncardiovascular diseases. This review aims to contribute to the ongoing research and development of innovative\ntherapies for hypertension management.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/0113816128337166241219081400","type":"journal-article","created":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T08:47:47Z","timestamp":1742374067000},"page":"1823-1843","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Solid Lipid Nanoparticles for the Management of Hypertension: Advancements and Challenges"],"prefix":"10.2174","volume":"31","author":[{"given":"Avinaba","family":"Das","sequence":"first","affiliation":[{"name":"Department of Pharmaceutics, Yenepoya Pharmacy College &amp; Research Centre, Yenepoya (Deemed to be University), Mangalore\n575018, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.H. Jaswanth","family":"Gowda","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, Yenepoya Pharmacy College &amp; Research Centre, Yenepoya (Deemed to be University), Mangalore\n575018, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umme","family":"Hani","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha 61421, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karthika","family":"Paul","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru\n570015, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Gulzar","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, Yenepoya Pharmacy College &amp; Research Centre, Yenepoya (Deemed to be University), Mangalore\n575018, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gholamreza","family":"Abdi","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, Persian Gulf Research Institute, Persian Gulf University, Bushehr\n75169, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharmin Sultana","family":"Shimu","sequence":"additional","affiliation":[{"name":"Department of Genetic Engineering and Biotechnology, University of Rajshahi, Rajshahi, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","reference":[{"key":"ref=1","year":"2024","unstructured":"Cardiovascular disease risk factors and mortality around the world.  Available from: \n https:\/\/www.thelancet.com\/infographics-do\/cardiovascular-disease-risk2024"},{"key":"ref=2","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1016\/S0140-6736(23)02871-4","volume":"403","author":"Drozd M.","year":"2024","unstructured":"Drozd M.; Cubbon R.; Inflammation, infection, and cardiovascular risk. Lancet  2024,403(10431),1022-1023","journal-title":"Lancet"},{"key":"ref=3","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1016\/S0140-6736(15)01225-8","volume":"387","author":"Ettehad D.","year":"2016","unstructured":"Ettehad D.; Emdin C.A.; Kiran A.; Anderson S.G.; Callender T.; Emberson J.; Chalmers J.; Rodgers A.; Rahimi K.; Blood pressure lowering for prevention of cardiovascular disease and death: A systematic review and meta-analysis. Lancet  2016,387(10022),957-967","journal-title":"Lancet"},{"key":"ref=4","doi-asserted-by":"publisher","first-page":"e484","DOI":"10.1016\/S2542-5196(22)00117-6","volume":"6","author":"Liu J.","year":"2022","unstructured":"Liu J.; Varghese B.M.; Hansen A.; Zhang Y.; Driscoll T.; Morgan G.; Dear K.; Gourley M.; Capon A.; Bi P.; Heat exposure and cardiovascular health outcomes: A systematic review and meta-analysis. Lancet Planet Health  2022,6(6),e484-e495","journal-title":"Lancet Planet Health"},{"key":"ref=5","doi-asserted-by":"publisher","first-page":"2361","DOI":"10.1016\/j.jacc.2022.11.005","volume":"80","author":"Vaduganathan M.","year":"2022","unstructured":"Vaduganathan M.; Mensah G.A.; Turco J.V.; Fuster V.; Roth G.A.; The global burden of cardiovascular diseases and risk. J Am Coll Cardiol  2022,80(25),2361-2371","journal-title":"J Am Coll Cardiol"},{"key":"ref=6","year":"2021","unstructured":"Cardiovascular diseases (CVDs).  Available from: \n https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/cardiovascular-diseases-(cvds)2021"},{"key":"ref=7","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1016\/S0140-6736(14)61468-9","volume":"386","author":"Poulter N.R.","year":"2015","unstructured":"Poulter N.R.; Prabhakaran D.; Caulfield M.; Hypertension. Lancet  2015,386(9995),801-812","journal-title":"Lancet"},{"key":"ref=8","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1016\/S0140-6736(22)01786-X","volume":"400","author":"Mackenzie I.S.","year":"2022","unstructured":"Mackenzie I.S.; Rogers A.; Poulter N.R.; Williams B.; Brown M.J.; Webb D.J.; Ford I.; Rorie D.A.; Guthrie G.; Grieve J.W.K.; Pigazzani F.; Rothwell P.M.; Young R.; McConnachie A.; Struthers A.D.; Lang C.C.; MacDonald T.M.; Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): A prospective, randomised, open-label, blinded-endpoint clinical trial. Lancet  2022,400(10361),1417-1425","journal-title":"Lancet"},{"key":"ref=9","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1016\/S1474-4422(23)00420-9","volume":"22","year":"2023","unstructured":"The global challenge of hypertension. Lancet Neurol  2023,22(12),1087","journal-title":"Lancet Neurol"},{"key":"ref=10","doi-asserted-by":"publisher","first-page":"1625","DOI":"10.1016\/S0140-6736(21)00590-0","volume":"397","author":"Rahimi K.","year":"2021","unstructured":"Rahimi K.; Bidel Z.; Nazarzadeh M.; Copland E.; Canoy D.; Ramakrishnan R.; Pinho-Gomes A-C.; Woodward M.; Adler A.; Agodoa L.; Algra A.; Asselbergs F.W.; Beckett N.S.; Berge E.; Black H.; Brouwers F.P.J.; Brown M.; Bulpitt C.J.; Byington R.P.; Cushman W.C.; Cutler J.; Devereaux R.B.; Dwyer J.; Estacio R.; Fagard R.; Fox K.; Fukui T.; Gupta A.K.; Holman R.R.; Imai Y.; Ishii M.; Julius S.; Kanno Y.; Kjeldsen S.E.; Kostis J.; Kuramoto K.; Lanke J.; Lewis E.; Lewis J.B.; Lievre M.; Lindholm L.H.; Lueders S.; MacMahon S.; Mancia G.; Matsuzaki M.; Mehlum M.H.; Nissen S.; Ogawa H.; Ogihara T.; Ohkubo T.; Palmer C.R.; Patel A.; Pfeffer M.A.; Pitt B.; Poulter N.R.; Rakugi H.; Reboldi G.; Reid C.; Remuzzi G.; Ruggenenti P.; Saruta T.; Schrader J.; Schrier R.; Sever P.; Sleight P.; Staessen J.A.; Suzuki H.; Thijs L.; Ueshima K.; Umemoto S.; van Gilst W.H.; Verdecchia P.; Wachtell K.; Whelton P.; Wing L.; Yui Y.; Yusuf S.; Zanchetti A.; Zhang Z-Y.; Anderson C.; Baigent C.; Brenner B.M.; Collins R.; de Zeeuw D.; Lubsen J.; Malacco E.; Neal B.; Perkovic V.; Rodgers A.; Rothwell P.; Salimi-Khorshidi G.; Sundstr\u00f6m J.; Turnbull F.; Viberti G.; Wang J.; Chalmers J.; Teo K.K.; Pepine C.J.; Davis B.R.; Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: An individual participant-level data meta-analysis. Lancet  2021,397(10285),1625-1636","journal-title":"Lancet"},{"key":"ref=11","unstructured":"First WHO report details devastating impact of hypertension and ways to stop it. 2023.   Available from: \n https:\/\/www.who.int\/ news\/item\/19-09-2023-first-who-report-details-devastating-impact-of-hypertension-and-ways-to-stop-it"},{"key":"ref=12","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1038\/s41440-024-01622-w","volume":"47","author":"Kario K.","year":"2024","unstructured":"Kario K.; Okura A.; Hoshide S.; Mogi M.; The WHO Global report 2023 on hypertension warning the emerging hypertension burden in globe and its treatment strategy. Hypertens Res  2024,47(5),1099-1102","journal-title":"Hypertens Res"},{"key":"ref=13","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1111\/j.1742-1241.2008.01713.x","volume":"62","author":"Haller H.","year":"2008","unstructured":"Haller H.; Effective management of hypertension with dihydropyridine calcium channel blocker-based combination therapy in patients at high cardiovascular risk. Int J Clin Pract  2008,62(5),781-790","journal-title":"Int J Clin Pract"},{"key":"ref=14","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1007\/s10557-021-07248-1","volume":"37","author":"Strauss M.H.","year":"2023","unstructured":"Strauss M.H.; Hall A.S.; Narkiewicz K.; The combination of beta-blockers and ACE inhibitors across the spectrum of cardiovascular diseases. Cardiovasc Drugs Ther  2023,37(4),757-770","journal-title":"Cardiovasc Drugs Ther"},{"key":"ref=15","author":"Herman L.L.","year":"2023","unstructured":"Herman L.L.; Padala S.A.; Ahmed I.; Bashir K.; Angiotensin-Converting Enzyme Inhibitors (ACEI).  Available from: \n https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK431051\/2023"},{"key":"ref=16","author":"Goyal A.","unstructured":"Goyal A.; Cusick A.S.; Thielemier B.; Inhibitors A.C.E.; ACE inhibitors. StatPearls","journal-title":"StatPearls"},{"key":"ref=17","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/s40264-014-0239-7","volume":"38","author":"Abraham H.M.A.","year":"2015","unstructured":"Abraham H.M.A.; White C.M.; White W.B.; The comparative efficacy and safety of the angiotensin receptor blockers in the management of hypertension and other cardiovascular diseases. Drug Saf  2015,38(1),33-54","journal-title":"Drug Saf"},{"key":"ref=18","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1080\/08998280.2003.11927893","volume":"16","author":"Barreras A.","year":"2003","unstructured":"Barreras A.; Gurk-Turner C.; Angiotensin II receptor blockers. Proc Bayl Univ Med Cent  2003,16(1),123-126","journal-title":"Proc Bayl Univ Med Cent"},{"key":"ref=19","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/S0002-9343(98)00239-3","volume":"105","author":"Suissa S.","year":"1998","unstructured":"Suissa S.; Bourgault C.; Barkun A.; Sheehy O.; Ernst P.; Antihypertensive drugs and the risk of gastrointestinal bleeding. Am J Med  1998,105(3),230-235","journal-title":"Am J Med"},{"key":"ref=20","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/bs.seda.2023.07.004","volume":"45","author":"Hall C.","year":"2023","unstructured":"Hall C.; Choi H.; Side effects of antihypertensive drugs. Side Effects of Drugs Annual  2023,45,199-208","journal-title":"Side Effects of Drugs Annual"},{"key":"ref=21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2016\/8525679","volume":"2016","author":"Sharma M.","year":"2016","unstructured":"Sharma M.; Sharma R.; Jain D.K.; Nanotechnology based approaches for enhancing oral bioavailability of poorly water soluble antihypertensive drugs. Scientifica  2016,2016,1-11","journal-title":"Scientifica"},{"key":"ref=22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/08982104.2024.2378130","volume":"12","author":"Raunak Salian T.","year":"2024","unstructured":"Raunak Salian T.; Noushida N.; Mohanto S.; Gowda B.H.J.; Chakraborty M.; Nasrine A.; Narayana S.; Ahmed M.G.; Development of optimized resveratrol\/piperine-loaded phytosomal nanocomplex for isoproterenol-induced myocardial infarction treatment. J Liposome Res  2024,12,1-18","journal-title":"J Liposome Res"},{"key":"ref=23","doi-asserted-by":"publisher","first-page":"103599","DOI":"10.1016\/j.drudis.2023.103599","volume":"28","author":"Mirhadi E.","year":"2023","unstructured":"Mirhadi E.; Kesharwani P.; Johnston T.P.; Sahebkar A.; Nanomedicine-mediated therapeutic approaches for pulmonary arterial hypertension. Drug Discov Today  2023,28(6),103599","journal-title":"Drug Discov Today"},{"key":"ref=24","doi-asserted-by":"publisher","first-page":"2506","DOI":"10.1161\/HYPERTENSIONAHA.123.19523","volume":"80","author":"Story D.","year":"2023","unstructured":"Story D.; Aminoroaya A.; Skelton Z.; Kumari M.; Zhang Y.; Smith B.R.; Nanoparticle-based therapies in hypertension. Hypertension  2023,80(12),2506-2514","journal-title":"Hypertension"},{"key":"ref=25","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1080\/10717544.2016.1255999","volume":"24","author":"Alam T.","year":"2017","unstructured":"Alam T.; Khan S.; Gaba B.; Haider M.F.; Baboota S.; Ali J.; Nanocarriers as treatment modalities for hypertension. Drug Deliv  2017,24(1),358-369","journal-title":"Drug Deliv"},{"key":"ref=26","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1038\/s41573-020-0090-8","volume":"20","author":"Mitchell M.J.","year":"2021","unstructured":"Mitchell M.J.; Billingsley M.M.; Haley R.M.; Wechsler M.E.; Peppas N.A.; Langer R.; Engineering precision nanoparticles for drug delivery. Nat Rev Drug Discov  2021,20(2),101-124","journal-title":"Nat Rev Drug Discov"},{"key":"ref=27","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1208\/s12249-023-02670-0","volume":"24","author":"Hani U.","year":"2023","unstructured":"Hani U.; Gowda B.H.J.; Haider N.; Ramesh K.V.R.N.S.; Paul K.; Ashique S.; Ahmed M.G.; Narayana S.; Mohanto S.; Kesharwani P.; Nanoparticle-based approaches for treatment of hematological malignancies: A comprehensive review. AAPS PharmSciTech  2023,24(8),233","journal-title":"AAPS PharmSciTech"},{"key":"ref=28","doi-asserted-by":"publisher","first-page":"103819","DOI":"10.1016\/j.drudis.2023.103819","volume":"29","author":"Khan M.S.","year":"2024","unstructured":"Khan M.S.; Jaswanth Gowda B.H.; Almalki W.H.; Singh T.; Sahebkar A.; Kesharwani P.; Unravelling the potential of mitochondria-targeted liposomes for enhanced cancer treatment. Drug Discov Today  2024,29(1),103819","journal-title":"Drug Discov Today"},{"key":"ref=29","doi-asserted-by":"publisher","first-page":"2307074","DOI":"10.1002\/adfm.202307074","volume":"34","author":"Gowda B.H.J.","year":"2024","unstructured":"Gowda B.H.J.; Ahmed M.G.; Almoyad M.A.A.; Wahab S.; Almalki W.H.; Kesharwani P.; Nanosponges as an emerging platform for cancer treatment and diagnosis. Adv Funct Mater  2024,34(7),2307074","journal-title":"Adv Funct Mater"},{"key":"ref=30","doi-asserted-by":"publisher","first-page":"105040","DOI":"10.1016\/j.jddst.2023.105040","volume":"89","author":"Banazadeh M.","year":"2023","unstructured":"Banazadeh M.; Behnam B.; Ganjooei N.A.; Gowda B.H.J.; Kesharwani P.; Sahebkar A.; Curcumin-based nanomedicines: A promising avenue for brain neoplasm therapy. J Drug Deliv Sci Technol  2023,89,105040","journal-title":"J Drug Deliv Sci Technol"},{"key":"ref=31","doi-asserted-by":"publisher","first-page":"116894","DOI":"10.1016\/j.envres.2023.116894","volume":"237","author":"Gowda B.H.J.","year":"2023","unstructured":"Gowda B.H.J.; Ahmed M.G.; Alshehri S.A.; Wahab S.; Vora L.K.; Singh Thakur R.R.; Kesharwani P.; The cubosome-based nanoplatforms in cancer therapy: Seeking new paradigms for cancer theranostics. Environ Res  2023,237(Pt 1),116894","journal-title":"Environ Res"},{"key":"ref=32","doi-asserted-by":"publisher","first-page":"112800","DOI":"10.1016\/j.eurpolymj.2024.112800","volume":"206","author":"Sameer Khan M.","year":"2024","unstructured":"Sameer Khan M.; Jaswanth Gowda B.H.; Hasan N.; Gupta G.; Singh T.; Md S.; Kesharwani P.; Carbon nanotube-mediated platinum-based drug delivery for the treatment of cancer: Advancements and future perspectives. Eur Polym J  2024,206,112800","journal-title":"Eur Polym J"},{"key":"ref=33","doi-asserted-by":"publisher","first-page":"105755","DOI":"10.1016\/j.jddst.2024.105755","volume":"97","author":"Arif Y.","year":"2024","unstructured":"Arif Y.; Sameeya N.; Hasan N.; Gowda B.H.J.; Gupta G.; Alsayari A.; Wahab S.; Kesharwani P.; Advancements in dendrimer-based drug delivery for combinatorial cancer therapy. J Drug Deliv Sci Technol  2024,97,105755","journal-title":"J Drug Deliv Sci Technol"},{"key":"ref=34","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1186\/s12951-024-02701-3","volume":"22","author":"Narayana S.","year":"2024","unstructured":"Narayana S.; Gowda B.H.J.; Hani U.; Shimu S.S.; Paul K.; Das A.; Ashique S.; Ahmed M.G.; Tarighat M.A.; Abdi G.; Inorganic nanoparticle-based treatment approaches for colorectal cancer: Recent advancements and challenges. J Nanobiotechnology  2024,22(1),427","journal-title":"J Nanobiotechnology"},{"key":"ref=35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/01932691.2022.2139716","volume":"45","author":"A S.","year":"2022","unstructured":"A S.; Ahmed M.G.; Gowda B.H.J.; Surya S.; Formulation and characteristic evaluation of tacrolimus cubosomal gel for vitiligo. J Dispers Sci Technol  2022,45,1-10","journal-title":"J Dispers Sci Technol"},{"key":"ref=36","doi-asserted-by":"publisher","first-page":"101319","DOI":"10.1016\/j.mtchem.2022.101319","volume":"27","author":"Gowda B.H.J.","year":"2023","unstructured":"Gowda B.H.J.; Mohanto S.; Singh A.; Bhunia A.; Abdelgawad M.A.; Ghosh S.; Ansari M.J.; Pramanik S.; Nanoparticle-based therapeutic approaches for wound healing: A review of the state-of-the-art. Mater Today Chem  2023,27,101319","journal-title":"Mater Today Chem"},{"key":"ref=37","doi-asserted-by":"publisher","first-page":"101894","DOI":"10.1016\/j.mtchem.2023.101894","volume":"35","author":"Nag S.","year":"2024","unstructured":"Nag S.; Mitra O.; P S.; Bhattacharjee A.; Mohanto S.; Gowda B.H.J.; Kar S.; Ramaiah S.; Anbarasu A.; Ahmed M.G.; Exploring the emerging trends in the synthesis and theranostic paradigms of cerium oxide nanoparticles (CeONPs): A comprehensive review. Mater Today Chem  2024,35,101894","journal-title":"Mater Today Chem"},{"key":"ref=38","doi-asserted-by":"publisher","first-page":"103959","DOI":"10.1016\/j.pdpdt.2023.103959","volume":"45","author":"Nag S.","year":"2024","unstructured":"Nag S.; Mitra O.; Tripathi G.; Adur I.; Mohanto S.; Nama M.; Samanta S.; Gowda B.H.J.; Subramaniyan V.; Sundararajan V.; Kumarasamy V.; Nanomaterials-assisted photothermal therapy for breast cancer: State-of-the-art advances and future perspectives. Photodiagn Photodyn Ther  2024,45,103959","journal-title":"Photodiagn Photodyn Ther"},{"key":"ref=39","doi-asserted-by":"publisher","first-page":"e10246","DOI":"10.1002\/btm2.10246","volume":"6","author":"Anselmo A.C.","year":"2021","unstructured":"Anselmo A.C.; Mitragotri S.; Nanoparticles in the clinic: An update post COVID-19 vaccines. Bioeng Transl Med  2021,6(3),e10246","journal-title":"Bioeng Transl Med"},{"key":"ref=40","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1186\/s12645-023-00174-x","volume":"14","author":"Liu Y.","year":"2023","unstructured":"Liu Y.; Cheng W.; Xin H.; Liu R.; Wang Q.; Cai W.; Peng X.; Yang F.; Xin H.; Nanoparticles advanced from preclinical studies to clinical trials for lung cancer therapy. Cancer Nanotechnol  2023,14(1),28","journal-title":"Cancer Nanotechnol"},{"key":"ref=41","doi-asserted-by":"publisher","first-page":"e10143","DOI":"10.1002\/btm2.10143","volume":"4","author":"Anselmo A.C.","year":"2019","unstructured":"Anselmo A.C.; Mitragotri S.; Nanoparticles in the clinic: An update. Bioeng Transl Med  2019,4(3),e10143","journal-title":"Bioeng Transl Med"},{"key":"ref=42","doi-asserted-by":"publisher","first-page":"3028","DOI":"10.1016\/j.apsb.2022.02.025","volume":"12","author":"Shan X.","year":"2022","unstructured":"Shan X.; Gong X.; Li J.; Wen J.; Li Y.; Zhang Z.; Current approaches of nanomedicines in the market and various stage of clinical translation. Acta Pharm Sin B  2022,12(7),3028-3048","journal-title":"Acta Pharm Sin B"},{"key":"ref=43","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1186\/s12951-018-0392-8","volume":"16","author":"Patra J.K.","year":"2018","unstructured":"Patra J.K.; Das G.; Fraceto L.F.; Campos E.V.R.; Rodriguez-Torres M.D.P.; Acosta-Torres L.S.; Diaz-Torres L.A.; Grillo R.; Swamy M.K.; Sharma S.; Habtemariam S.; Shin H.S.; Nano based drug delivery systems: Recent developments and future prospects. J Nanobiotechnology  2018,16(1),71","journal-title":"J Nanobiotechnology"},{"key":"ref=44","doi-asserted-by":"publisher","first-page":"123037","DOI":"10.1016\/j.molliq.2023.123037","volume":"390","author":"Hani U.","year":"2023","unstructured":"Hani U.; Jaswanth Gowda B.H.; Siddiqua A.; Wahab S.; Begum M.Y.; Sathishbabu P.; Usmani S.; Ahmad M.P.; Herbal approach for treatment of cancer using curcumin as an anticancer agent: A review on novel drug delivery systems. J Mol Liq  2023,390,123037","journal-title":"J Mol Liq"},{"key":"ref=45","doi-asserted-by":"publisher","first-page":"110805","DOI":"10.1016\/j.mehy.2022.110805","volume":"161","author":"Gowda B.H.J.","year":"2022","unstructured":"Gowda B.H.J.; Ahmed M.G.; Husain A.; Transferosomal in situ gel administered through umbilical skin tissues for improved systemic bioavailability of drugs: A novel strategy to replace conventional transdermal route. Med Hypotheses  2022,161,110805","journal-title":"Med Hypotheses"},{"key":"ref=46","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s43094-021-00331-2","volume":"7","author":"Narayana S.","year":"2021","unstructured":"Narayana S.; Ahmed M.G.; Gowda B.H.J.; Shetty P.K.; Nasrine A.; Thriveni M.; Noushida N.; Sanjana A.; Recent advances in ocular drug delivery systems and targeting VEGF receptors for management of ocular angiogenesis: A comprehensive review. Future J Pharm Sci  2021,7(1),1-21","journal-title":"Future J Pharm Sci"},{"key":"ref=47","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/s12943-022-01708-4","volume":"22","author":"Zeng L.","year":"2023","unstructured":"Zeng L.; Gowda B.H.J.; Ahmed M.G.; Abourehab M.A.S.; Chen Z.S.; Zhang C.; Li J.; Kesharwani P.; Advancements in nanoparticle-based treatment approaches for skin cancer therapy. Mol Cancer  2023,22(1),10","journal-title":"Mol Cancer"},{"key":"ref=48","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1038\/s41551-021-00698-w","volume":"5","author":"Vargason A.M.","year":"2021","unstructured":"Vargason A.M.; Anselmo A.C.; Mitragotri S.; The evolution of commercial drug delivery technologies. Nat Biomed Eng  2021,5(9),951-967","journal-title":"Nat Biomed Eng"},{"key":"ref=49","doi-asserted-by":"publisher","first-page":"7767","DOI":"10.3390\/molecules28237767","volume":"28","author":"Hu Y.","year":"2023","unstructured":"Hu Y.; Song J.; Feng A.; Li J.; Li M.; Shi Y.; Sun W.; Li L.; Recent advances in nanotechnology-based targeted delivery systems of active constituents in natural medicines for cancer treatment. Molecules  2023,28(23),7767","journal-title":"Molecules"},{"key":"ref=50","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1007\/978-981-97-3925-7_12","author":"Gowda B.H.J.","year":"2024","unstructured":"Gowda B.H.J.; Vora L.K.; Gade S.; Glover K.; Ahmed M.G.; Thakur R.R.S.;  Therapeutic applications of nanobiomaterials for the management of ocular diseases  2024,329-348","journal-title":"Therapeutic applications of nanobiomaterials for the management of ocular diseases"},{"key":"ref=51","doi-asserted-by":"publisher","first-page":"100124","DOI":"10.1016\/j.rsurfi.2023.100124","volume":"11","author":"Khafoor A.A.","year":"2023","unstructured":"Khafoor A.A.; Karim A.S.; Sajadi S.M.; Recent progress in synthesis of nano based liposomal drug delivery systems: A glance to their medicinal applications. Results in Surfaces and Interfaces  2023,11,100124","journal-title":"Results in Surfaces and Interfaces"},{"key":"ref=52","doi-asserted-by":"publisher","first-page":"102451","DOI":"10.1016\/j.cis.2021.102451","volume":"294","author":"Jurak M.","year":"2021","unstructured":"Jurak M.; Wi\u0105cek A.E.; \u0141adniak A.; Przykaza K.; Szafran K.; What affects the biocompatibility of polymers? Adv Colloid Interface Sci  2021,294,102451","journal-title":"Adv Colloid Interface Sci"},{"key":"ref=53","doi-asserted-by":"publisher","first-page":"371","DOI":"10.3390\/macromol3020023","volume":"3","author":"Silva R.R.A.","year":"2023","unstructured":"Silva R.R.A.; Marques C.S.; Arruda T.R.; Teixeira S.C.; de Oliveira T.V.; Biodegradation of polymers: Stages, measurement, standards and prospects. Macromol  2023,3(2),371-399","journal-title":"Macromol"},{"key":"ref=54","doi-asserted-by":"publisher","first-page":"3015","DOI":"10.3390\/polym13173015","volume":"13","author":"Kalirajan C.","year":"2021","unstructured":"Kalirajan C.; Dukle A.; Nathanael A.J.; Oh T.H.; Manivasagam G.; A critical review on polymeric biomaterials for biomedical applications. Polymers  2021,13(17),3015","journal-title":"Polymers"},{"key":"ref=55","doi-asserted-by":"publisher","first-page":"26777","DOI":"10.1039\/D0RA03491F","volume":"10","author":"Duan Y.","year":"2020","unstructured":"Duan Y.; Dhar A.; Patel C.; Khimani M.; Neogi S.; Sharma P.; Siva Kumar N.; Vekariya R.L.; A brief review on solid lipid nanoparticles: Part and parcel of contemporary drug delivery systems. RSC Advances  2020,10(45),26777-26791","journal-title":"RSC Advances"},{"key":"ref=56","doi-asserted-by":"publisher","first-page":"30902","DOI":"10.1039\/C4RA17127F","volume":"5","author":"Aditya N.P.","year":"2015","unstructured":"Aditya N.P.; Ko S.; Solid lipid nanoparticles (SLNs): Delivery vehicles for food bioactives. RSC Advances  2015,5(39),30902-30911","journal-title":"RSC Advances"},{"key":"ref=57","doi-asserted-by":"publisher","first-page":"587997","DOI":"10.3389\/fmolb.2020.587997","volume":"7","author":"Scioli Montoto S.","year":"2020","unstructured":"Scioli Montoto S.; Muraca G.; Ruiz M.E.; Solid lipid nanoparticles for drug delivery: Pharmacological and biopharmaceutical aspects. Front Mol Biosci  2020,7,587997","journal-title":"Front Mol Biosci"},{"key":"ref=58","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/00914037.2024.2344603","author":"Garg G.","year":"2024","unstructured":"Garg G.; Garg S.; Patel P.; Das Gupta G.; Das Kurmi B.; Advances in solid-lipid nanoparticle chemistry as drug delivery vehicles Int J Polym Mater Polym Biomater  2024,1-15","journal-title":"Int J Polym Mater Polym Biomater"},{"key":"ref=59","doi-asserted-by":"publisher","first-page":"1775","DOI":"10.1007\/s10072-019-03913-4","volume":"40","author":"Gasparini S.","year":"2019","unstructured":"Gasparini S.; Ferlazzo E.; Sueri C.; Cianci V.; Ascoli M.; Cavalli S.M.; Beghi E.; Belcastro V.; Bianchi A.; Benna P.; Cantello R.; Consoli D.; De Falco F.A.; Di Gennaro G.; Gambardella A.; Gigli G.L.; Iudice A.; Labate A.; Michelucci R.; Paciaroni M.; Palumbo P.; Primavera A.; Sartucci F.; Striano P.; Villani F.; Russo E.; De Sarro G.; Aguglia U.; Hypertension, seizures, and epilepsy: A review on pathophysiology and management. Neurol Sci  2019,40(9),1775-1783","journal-title":"Neurol Sci"},{"key":"ref=60","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.2147\/VHRM.S4009","volume":"4","author":"Furuya M.","year":"2008","unstructured":"Furuya M.; Ishida J.; Aoki I.; Fukamizu A.; Pathophysiology of placentation abnormalities in pregnancy-induced hypertension. Vasc Health Risk Manag  2008,4(6),1301-1313","journal-title":"Vasc Health Risk Manag"},{"key":"ref=61","doi-asserted-by":"publisher","first-page":"38","DOI":"10.3390\/diseases6020038","volume":"6","author":"Lan N.S.H.","year":"2018","unstructured":"Lan N.S.H.; Massam B.D.; Kulkarni S.S.; Lang C.C.; Pulmonary arterial hypertension: Pathophysiology and treatment. Diseases  2018,6(2),38","journal-title":"Diseases"},{"key":"ref=62","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1080\/14779072.2018.1540301","volume":"16","author":"Saxena T.","year":"2018","unstructured":"Saxena T.; Ali A.O.; Saxena M.; Pathophysiology of essential hypertension: An update. Expert Rev Cardiovasc Ther  2018,16(12),879-887","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"ref=63","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1161\/HYPERTENSIONAHA.107.108837","volume":"51","author":"LaMarca B.D.","year":"2008","unstructured":"LaMarca B.D.; Gilbert J.; Granger J.P.; Recent progress toward the understanding of the pathophysiology of hypertension during preeclampsia. Hypertension  2008,51(4),982-988","journal-title":"Hypertension"},{"key":"ref=64","doi-asserted-by":"publisher","first-page":"23","DOI":"10.5301\/JN.2010.4729","volume":"24","author":"Montecucco F.","year":"2011","unstructured":"Montecucco F.; Pende A.; Quercioli A.; Mach F.; Inflammation in the pathophysiology of essential hypertension. J Nephrol  2011,24(1),23-34","journal-title":"J Nephrol"},{"key":"ref=65","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1007\/s11886-020-1257-y","volume":"22","author":"Salman L.A.","year":"2020","unstructured":"Salman L.A.; Shulman R.; Cohen J.B.; Obstructive sleep apnea, hypertension, and cardiovascular risk: Epidemiology, pathophysiology, and management. Curr Cardiol Rep  2020,22(2),6","journal-title":"Curr Cardiol Rep"},{"key":"ref=66","doi-asserted-by":"publisher","first-page":"80","DOI":"10.21037\/gs.2019.12.03","volume":"9","author":"Shariq O.A.","year":"2020","unstructured":"Shariq O.A.; McKenzie T.J.; Obesity-related hypertension: A review of pathophysiology, management, and the role of metabolic surgery. Gland Surg  2020,9(1),80-93","journal-title":"Gland Surg"},{"key":"ref=67","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/s11906-012-0320-5","volume":"15","author":"Thoonen R.","year":"2013","unstructured":"Thoonen R.; Sips P.Y.; Bloch K.D.; Buys E.S.; Pathophysiology of hypertension in the absence of nitric oxide\/cyclic GMP signaling. Curr Hypertens Rep  2013,15(1),47-58","journal-title":"Curr Hypertens Rep"},{"key":"ref=68","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1136\/heart.89.9.1104","volume":"89","author":"Mayet J.","year":"2003","unstructured":"Mayet J.; Hughes A.; Cardiac and vascular pathophysiology in hypertension. Br Heart J  2003,89(9),1104-1109","journal-title":"Br Heart J"},{"key":"ref=69","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1038\/hr.2010.264","volume":"34","author":"Rodrigo R.","year":"2011","unstructured":"Rodrigo R.; Gonz\u00e1lez J.; Paoletto F.; The role of oxidative stress in the pathophysiology of hypertension. Hypertens Res  2011,34(4),431-440","journal-title":"Hypertens Res"},{"key":"ref=70","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1016\/j.jash.2008.02.001","volume":"2","author":"Pandey K.N.","year":"2008","unstructured":"Pandey K.N.; Emerging roles of natriuretic peptides and their receptors in pathophysiology of hypertension and cardiovascular regulation. J Am Soc Hypertens  2008,2(4),210-226","journal-title":"J Am Soc Hypertens"},{"key":"ref=71","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-88369-6.00005-0","author":"Hall J.E.","year":"2024, pp. 71-86","unstructured":"Hall J.E.; Omoto A.C.M.; Wang Z.; Mouton A.; Li X.; Hall M.E.;  Pathophysiology of Hypertension  2024, pp. 71-86","journal-title":"Pathophysiology of Hypertension"},{"key":"ref=72","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.ejpb.2016.10.021","volume":"110","author":"Zoubari G.","year":"2017","unstructured":"Zoubari G.; Staufenbiel S.; Volz P.; Alexiev U.; Bodmeier R.; Effect of drug solubility and lipid carrier on drug release from lipid nanoparticles for dermal delivery. Eur J Pharm Biopharm  2017,110,39-46","journal-title":"Eur J Pharm Biopharm"},{"key":"ref=73","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/j.ejpb.2014.05.004","volume":"87","author":"Gastaldi L.","year":"2014","unstructured":"Gastaldi L.; Battaglia L.; Peira E.; Chirio D.; Muntoni E.; Solazzi I.; Gallarate M.; Dosio F.; Solid lipid nanoparticles as vehicles of drugs to the brain: Current state of the art. Eur J Pharm Biopharm  2014,87(3),433-444","journal-title":"Eur J Pharm Biopharm"},{"key":"ref=74","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/S0939-6411(00)00087-4","volume":"50","author":"M\u00fcller R.H.","year":"2000","unstructured":"M\u00fcller R.H.; M\u00e4der K.; Gohla S.; Solid lipid nanoparticles (SLN) for controlled drug delivery - A review of the state of the art. Eur J Pharm Biopharm  2000,50(1),161-177","journal-title":"Eur J Pharm Biopharm"},{"key":"ref=75","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/S0939-6411(97)00150-1","volume":"45","author":"zur M\u00fchlen A.","year":"1998","unstructured":"zur M\u00fchlen A.; Schwarz C.; Mehnert W.; Solid lipid nanoparticles (SLN) for controlled drug delivery \u2013 Drug release and release mechanism. Eur J Pharm Biopharm  1998,45(2),149-155","journal-title":"Eur J Pharm Biopharm"},{"key":"ref=76","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1016\/j.addr.2011.05.017","volume":"63","author":"Cai S.","year":"2011","unstructured":"Cai S.; Yang Q.; Bagby T.R.; Forrest M.L.; Lymphatic drug delivery using engineered liposomes and solid lipid nanoparticles. Adv Drug Deliv Rev  2011,63(10-11),901-908","journal-title":"Adv Drug Deliv Rev"},{"key":"ref=77","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1016\/j.addr.2007.09.010","volume":"60","author":"Chen M.L.","year":"2008","unstructured":"Chen M.L.; Lipid excipients and delivery systems for pharmaceutical development: A regulatory perspective. Adv Drug Deliv Rev  2008,60(6),768-777","journal-title":"Adv Drug Deliv Rev"},{"key":"ref=78","doi-asserted-by":"publisher","first-page":"111305","DOI":"10.1016\/j.colsurfb.2020.111305","volume":"196","author":"Salah E.","year":"2020","unstructured":"Salah E.; Abouelfetouh M.M.; Pan Y.; Chen D.; Xie S.; Solid lipid nanoparticles for enhanced oral absorption: A review. Colloids Surf B Biointerfaces  2020,196,111305","journal-title":"Colloids Surf B Biointerfaces"},{"key":"ref=79","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.jfda.2017.02.001","volume":"25","author":"Lin C.H.","year":"2017","unstructured":"Lin C.H.; Chen C.H.; Lin Z.C.; Fang J.Y.; Recent advances in oral delivery of drugs and bioactive natural products using solid lipid nanoparticles as the carriers. J Food Drug Anal  2017,25(2),219-234","journal-title":"J Food Drug Anal"},{"key":"ref=80","doi-asserted-by":"crossref","first-page":"288","DOI":"10.4103\/1735-5362.235156","volume":"13","author":"Ghasemiyeh P.","year":"2018","unstructured":"Ghasemiyeh P.; Mohammadi-Samani S.; Solid lipid nanoparticles and nanostructured lipid carriers as novel drug delivery systems: Applications, advantages and disadvantages. Res Pharm Sci  2018,13(4),288-303","journal-title":"Res Pharm Sci"},{"key":"ref=81","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/B978-0-12-816506-5.00003-6","author":"Shah M.K.","year":"2019","unstructured":"Shah M.K.; Khatri P.; Vora N.; Patel N.K.; Jain S.; Lin S.;  Lipid nanocarriers: Preparation, characterization and absorption mechanism and applications to improve oral bioavailability of poorly water- soluble drugs  2019,117-147","journal-title":"Lipid nanocarriers: Preparation, characterization and absorption mechanism and applications to improve oral bioavailability of poorly water- soluble drugs"},{"key":"ref=82","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/B978-0-12-816200-2.00019-0","author":"Chircov C.","year":"2019","unstructured":"Chircov C.; Grumezescu A.M.;  Nanoemulsion preparation, characterization, and application in the field of biomedicine  2019,169-188","journal-title":"Nanoemulsion preparation, characterization, and application in the field of biomedicine"},{"key":"ref=83","doi-asserted-by":"publisher","first-page":"104475","DOI":"10.1016\/j.dib.2019.104475","volume":"26","author":"Duong V.A.","year":"2019","unstructured":"Duong V.A.; Nguyen T.T.L.; Maeng H.J.; Chi S.C.; Data on optimization and drug release kinetics of nanostructured lipid carriers containing ondansetron hydrochloride prepared by cold high-pressure homogenization method. Data Brief  2019,26,104475","journal-title":"Data Brief"},{"key":"ref=84","doi-asserted-by":"publisher","first-page":"103839","DOI":"10.1016\/j.jddst.2022.103839","volume":"77","author":"Viegas C.","year":"2022","unstructured":"Viegas C.; Seck F.; Fonte P.; An insight on lipid nanoparticles for therapeutic proteins delivery. J Drug Deliv Sci Technol  2022,77,103839","journal-title":"J Drug Deliv Sci Technol"},{"key":"ref=85","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/S0079-6123(08)80010-6","volume":"180","author":"Gasco M.R.","year":"2009","unstructured":"Gasco M.R.; Priano L.; Zara G.P.; Solid lipid nanoparticles and microemulsions for drug delivery. Prog Brain Res  2009,180,181-192","journal-title":"Prog Brain Res"},{"key":"ref=86","doi-asserted-by":"publisher","first-page":"4781","DOI":"10.3390\/molecules25204781","volume":"25","author":"Duong V.A.","year":"2020","unstructured":"Duong V.A.; Nguyen T.T.L.; Maeng H.J.; Preparation of solid lipid nanoparticles and nanostructured lipid carriers for drug delivery and the effects of preparation parameters of solvent injection method. Molecules  2020,25(20),4781","journal-title":"Molecules"},{"key":"ref=87","doi-asserted-by":"publisher","first-page":"113821","DOI":"10.1016\/j.foodres.2023.113821","volume":"176","author":"Stahl M.A.","year":"2024","unstructured":"Stahl M.A.; L\u00fcdtke F.L.; Grimaldi R.; Gigante M.L.; Ribeiro A.P.B.; Characterization and stability of solid lipid nanoparticles produced from different fully hydrogenated oils. Food Res Int  2024,176,113821","journal-title":"Food Res Int"},{"key":"ref=88","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1016\/j.colsurfb.2011.03.035","volume":"86","author":"Silva A.C.","year":"2011","unstructured":"Silva A.C.; Gonz\u00e1lez-Mira E.; Garc\u00eda M.L.; Egea M.A.; Fonseca J.; Silva R.; Santos D.; Souto E.B.; Ferreira D.; Preparation, characterization and biocompatibility studies on risperidone-loaded solid lipid nanoparticles (SLN): High pressure homogenization versus ultrasound. Colloids Surf B Biointerfaces  2011,86(1),158-165","journal-title":"Colloids Surf B Biointerfaces"},{"key":"ref=89","doi-asserted-by":"publisher","first-page":"101185","DOI":"10.1016\/j.jddst.2019.101185","volume":"53","author":"Duong V.A.","year":"2019","unstructured":"Duong V.A.; Nguyen T.T.L.; Maeng H.J.; Chi S.C.; Nanostructured lipid carriers containing ondansetron hydrochloride by cold high- pressure homogenization method: Preparation, characterization, and pharmacokinetic evaluation. J Drug Deliv Sci Technol  2019,53,101185","journal-title":"J Drug Deliv Sci Technol"},{"key":"ref=90","doi-asserted-by":"publisher","first-page":"353","DOI":"10.3109\/10837450.2010.542163","volume":"17","author":"Kasongo K.W.","year":"2012","unstructured":"Kasongo K.W.; M\u00fcller R.H.; Walker R.B.; The use of hot and cold high pressure homogenization to enhance the loading capacity and encapsulation efficiency of nanostructured lipid carriers for the hydrophilic antiretroviral drug, didanosine for potential administration to paediatric patients. Pharm Dev Technol  2012,17(3),353-362","journal-title":"Pharm Dev Technol"},{"key":"ref=91","doi-asserted-by":"publisher","first-page":"e03846","DOI":"10.1016\/j.heliyon.2020.e03846","volume":"6","author":"Soni G.","year":"2020","unstructured":"Soni G.; Kale K.; Shetty S.; Gupta M.K.; Yadav K.S.; Quality by design (QbD) approach in processing polymeric nanoparticles loading anticancer drugs by high pressure homogenizer. Heliyon  2020,6(4),e03846","journal-title":"Heliyon"},{"key":"ref=92","doi-asserted-by":"publisher","first-page":"1559","DOI":"10.1016\/j.foohum.2023.11.003","volume":"1","author":"Chauhan O.P.","year":"2023","unstructured":"Chauhan O.P.; Chandel A.; Smitha P.M.; Semwal A.D.; High pressure homogenization and retention of bioactive compounds in fruits and vegetables products. Food and Humanity  2023,1,1559-1569","journal-title":"Food and Humanity"},{"key":"ref=93","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1016\/j.cherd.2023.12.026","volume":"202","author":"Inguva P.","year":"2024","unstructured":"Inguva P.; Grasselli S.; Heng P.W.S.; High pressure homogenization- An update on its usage and understanding. Chem Eng Res Des  2024,202,284-302","journal-title":"Chem Eng Res Des"},{"key":"ref=94","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1007\/s13346-020-00733-4","volume":"10","author":"Yadav M.","year":"2020","unstructured":"Yadav M.; Schiavone N.; Guzman-Aranguez A.; Giansanti F.; Papucci L.; Perez de Lara M.J.; Singh M.; Kaur I.P.; Atorvastatin-loaded solid lipid nanoparticles as eye drops: Proposed treatment option for age-related macular degeneration (AMD). Drug Deliv Transl Res  2020,10(4),919-944","journal-title":"Drug Deliv Transl Res"},{"key":"ref=95","doi-asserted-by":"publisher","first-page":"109874","DOI":"10.1016\/j.msec.2019.109874","volume":"103","author":"\u00dcner M.","year":"2019","unstructured":"\u00dcner M.; Yener G.; Erg\u00fcven M.; Design of colloidal drug carriers of celecoxib for use in treatment of breast cancer and leukemia. Mater Sci Eng C  2019,103,109874","journal-title":"Mater Sci Eng C"},{"key":"ref=96","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1080\/1061186021000001832","volume":"10","author":"Olbrich C.","year":"2002","unstructured":"Olbrich C.; Gessner A.; Kayser O.; M\u00fcller R.H.; Lipid-drug-conjugate (LDC) nanoparticles as novel carrier system for the hydrophilic antitrypanosomal drug diminazenediaceturate. J Drug Target  2002,10(5),387-396","journal-title":"J Drug Target"},{"key":"ref=97","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/j.ejpb.2016.06.014","volume":"108","author":"Suter F.","year":"2016","unstructured":"Suter F.; Schmid D.; Wandrey F.; Z\u00fclli F.; Heptapeptide-loaded solid lipid nanoparticles for cosmetic anti-aging applications. Eur J Pharm Biopharm  2016,108,304-309","journal-title":"Eur J Pharm Biopharm"},{"key":"ref=98","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1007\/s11095-006-9225-9","volume":"24","author":"\u0160tecov\u00e1 J.","year":"2007","unstructured":"\u0160tecov\u00e1 J.; Mehnert W.; Blaschke T.; Kleuser B.; Sivaramakrishnan R.; Zouboulis C.C.; Seltmann H.; Korting H.C.; Kramer K.D.; Sch\u00e4fer-Korting M.; Cyproterone acetate loading to lipid nanoparticles for topical acne treatment: Particle characterisation and skin uptake. Pharm Res  2007,24(5),991-1000","journal-title":"Pharm Res"},{"key":"ref=99","first-page":"570","volume":"96","author":"B\u00e4ttig K.","year":"1966","unstructured":"B\u00e4ttig K.; Fischer H.; Do patent analgetics and placebos have a different effect on subjective feelings, personality tests and psychomotor performance? Schweiz Med Wochenschr  1966,96(17),570-575","journal-title":"Schweiz Med Wochenschr"},{"key":"ref=100","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1080\/1061186X.2017.1350857","volume":"26","author":"Sharma G.","year":"2018","unstructured":"Sharma G.; Chopra K.; Puri S.; Bishnoi M.; Rishi P.; Kaur I.P.; Topical delivery of TRPsiRNA-loaded solid lipid nanoparticles confer reduced pain sensation via TRPV1 silencing, in rats. J Drug Target  2018,26(2),135-149","journal-title":"J Drug Target"},{"key":"ref=101","first-page":"653","volume":"68","author":"Zhang S-J.","year":"2013","unstructured":"Zhang S-J.; Zhang Y-T.; Zhao J-H.; Shen L-N.; Shi F.; Feng N-P.; Preparation and in vitro anti-tumor properties of toad venom extract- loaded solid lipid nanoparticles. Pharmazie  2013,68(8),653-660","journal-title":"Pharmazie"},{"key":"ref=102","doi-asserted-by":"publisher","first-page":"1375","DOI":"10.1016\/j.msec.2012.04.017","volume":"32","author":"Severino P.","year":"2012","unstructured":"Severino P.; Santana M.H.A.; Souto E.B.; Optimizing S.L.N.; Optimizing SLN and NLC by 22 full factorial design: Effect of homogenization technique. Mater Sci Eng C  2012,32(6),1375-1379","journal-title":"Mater Sci Eng C"},{"key":"ref=103","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1111\/lam.12886","volume":"66","author":"Fazly Bazzaz B.S.","year":"2018","unstructured":"Fazly Bazzaz B.S.; Khameneh B.; Namazi N.; Iranshahi M.; Davoodi D.; Golmohammadzadeh S.; Solid lipid nanoparticles carrying Eugenia caryophyllata essential oil: The novel nanoparticulate systems with broad-spectrum antimicrobial activity. Lett Appl Microbiol  2018,66(6),506-513","journal-title":"Lett Appl Microbiol"},{"key":"ref=104","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1007\/s13197-017-2937-5","volume":"55","author":"Akhoond Zardini A.","year":"2018","unstructured":"Akhoond Zardini A.; Mohebbi M.; Farhoosh R.; Bolurian S.; Production and characterization of nanostructured lipid carriers and solid lipid nanoparticles containing lycopene for food fortification. J Food Sci Technol  2018,55(1),287-298","journal-title":"J Food Sci Technol"},{"key":"ref=105","doi-asserted-by":"publisher","first-page":"1166","DOI":"10.1007\/s13346-020-00839-9","volume":"11","author":"Shah P.","year":"2021","unstructured":"Shah P.; Chavda K.; Vyas B.; Patel S.; Formulation development of linagliptin solid lipid nanoparticles for oral bioavailability enhancement: Role of P-gp inhibition. Drug Deliv Transl Res  2021,11(3),1166-1185","journal-title":"Drug Deliv Transl Res"},{"key":"ref=106","doi-asserted-by":"publisher","first-page":"1188","DOI":"10.1080\/10717544.2020.1803449","volume":"27","author":"Zhu C.","year":"2020","unstructured":"Zhu C.; Li W.; Wang X.; Xue J.; Zhao L.; Song Y.; Zhou T.; Zhang M.; Thiopental sodium loaded solid lipid nano-particles attenuates obesity-induced cardiac dysfunction and cardiac hypertrophy via inactivation of inflammatory pathway. Drug Deliv  2020,27(1),1188-1200","journal-title":"Drug Deliv"},{"key":"ref=107","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2018\/3021738","volume":"2018","author":"Masiiwa W.L.","year":"2018","unstructured":"Masiiwa W.L.; Gadaga L.L.; Intestinal permeability of artesunate-loaded solid lipid nanoparticles using the everted gut method. J Drug Deliv  2018,2018,1-9","journal-title":"J Drug Deliv"},{"key":"ref=108","doi-asserted-by":"publisher","first-page":"818","DOI":"10.2174\/1567201814666170525121049","volume":"15","author":"Yasir M.","year":"2018","unstructured":"Yasir M.; Gaur P.K.; Puri D.; Preeti S.; Kumar S.S.; Solid lipid nanoparticles approach for lymphatic targeting through intraduodenal delivery of quetiapine fumarate. Curr Drug Deliv  2018,15(6),818-828","journal-title":"Curr Drug Deliv"},{"key":"ref=109","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.ejpb.2017.04.007","volume":"117","author":"Shah R.M.","year":"2017","unstructured":"Shah R.M.; Eldridge D.S.; Palombo E.A.; Harding I.H.; Microwave-assisted microemulsion technique for production of miconazole nitrate- and econazole nitrate-loaded solid lipid nanoparticles. Eur J Pharm Biopharm  2017,117,141-150","journal-title":"Eur J Pharm Biopharm"},{"key":"ref=110","doi-asserted-by":"publisher","first-page":"2283","DOI":"10.1016\/S0142-9612(01)00362-3","volume":"23","author":"Cortesi R.","year":"2002","unstructured":"Cortesi R.; Esposjto E.; Luca G.; Nastruzzi C.; Production of lipospheres as carriers for bioactive compounds. Biomaterials  2002,23(11),2283-2294","journal-title":"Biomaterials"},{"key":"ref=111","doi-asserted-by":"publisher","first-page":"96","DOI":"10.3390\/pharmaceutics12020096","volume":"12","author":"Fathy Abd-Ellatef G.E.","year":"2020","unstructured":"Fathy Abd-Ellatef G.E.; Gazzano E.; Chirio D.; Ragab Hamed A.; Belisario D.C.; Zuddas C.; Peira E.; Rolando B.; Kopecka J.; Assem Said Marie M.; Sapino S.; Ramadan Fahmy S.; Gallarate M.; Zaki Abdel-Hamid A-H.; Riganti C.; Curcumin-loaded solid lipid nanoparticles bypass p-glycoprotein mediated doxorubicin resistance in triple negative breast cancer cells. Pharmaceutics  2020,12(2),96","journal-title":"Pharmaceutics"},{"key":"ref=112","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1080\/02652048.2020.1823499","volume":"37","author":"Gupta S.","year":"2020","unstructured":"Gupta S.; Wairkar S.; Bhatt L.K.; Isotretinoin and \u03b1-tocopherol acetate-loaded solid lipid nanoparticle topical gel for the treatment of acne. J Microencapsul  2020,37(8),557-565","journal-title":"J Microencapsul"},{"key":"ref=113","doi-asserted-by":"publisher","first-page":"101451","DOI":"10.1016\/j.jddst.2019.101451","volume":"55","author":"Mukherjee S.","year":"2020","unstructured":"Mukherjee S.; Maity S.; Ghosh B.; Chakraborty T.; Mondal A.; Bishayee A.; Assessment of the antidiabetic potentiality of glyburide loaded glyceryl monostearate solid lipid nanoparticles. J Drug Deliv Sci Technol  2020,55,101451","journal-title":"J Drug Deliv Sci Technol"},{"key":"ref=114","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/S0378-5173(03)00135-2","volume":"257","author":"Trotta M.","year":"2003","unstructured":"Trotta M.; Debernardi F.; Caputo O.; Preparation of solid lipid nanoparticles by a solvent emulsification\u2013diffusion technique. Int J Pharm  2003,257(1-2),153-160","journal-title":"Int J Pharm"},{"key":"ref=115","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/S0378-5173(02)00081-9","volume":"239","author":"Hu F.Q.","year":"2002","unstructured":"Hu F.Q.; Yuan H.; Zhang H.H.; Fang M.; Preparation of solid lipid nanoparticles with clobetasol propionate by a novel solvent diffusion method in aqueous system and physicochemical characterization. Int J Pharm  2002,239(1-2),121-128","journal-title":"Int J Pharm"},{"key":"ref=116","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/j.ijpharm.2004.10.014","volume":"288","author":"Trotta M.","year":"2005","unstructured":"Trotta M.; Cavalli R.; Carlotti M.E.; Battaglia L.; Debernardi F.; Solid lipid micro-particles carrying insulin formed by solvent-in-water emulsion\u2013diffusion technique. Int J Pharm  2005,288(2),281-288","journal-title":"Int J Pharm"},{"key":"ref=117","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1080\/10837450.2019.1703739","volume":"25","author":"Yassemi A.","year":"2020","unstructured":"Yassemi A.; Kashanian S.; Zhaleh H.; Folic acid receptor-targeted solid lipid nanoparticles to enhance cytotoxicity of letrozole through induction of caspase-3 dependent-apoptosis for breast cancer treatment. Pharm Dev Technol  2020,25(4),397-407","journal-title":"Pharm Dev Technol"},{"key":"ref=118","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1080\/02652040701532981","volume":"24","author":"Battaglia L.","year":"2007","unstructured":"Battaglia L.; Trotta M.; Gallarate M.; Carlotti M.E.; Zara G.I.A.N.P.; Bargoni A.; Solid lipid nanoparticles formed by solvent-in-water emulsion\u2013diffusion technique: Development and influence on insulin stability. J Microencapsul  2007,24(7),672-684","journal-title":"J Microencapsul"},{"key":"ref=119","doi-asserted-by":"publisher","first-page":"1535","DOI":"10.1111\/jphp.12644","volume":"68","author":"Dhaundiyal A.","year":"2016","unstructured":"Dhaundiyal A.; Jena S.K.; Samal S.K.; Sonvane B.; Chand M.; Sangamwar A.T.; Alpha-lipoic acid\u2013stearylamine conjugate-based solid lipid nanoparticles for tamoxifen delivery: Formulation, optimization, in vivo pharmacokinetic and hepatotoxicity study. J Pharm Pharmacol  2016,68(12),1535-1550","journal-title":"J Pharm Pharmacol"},{"key":"ref=120","doi-asserted-by":"publisher","first-page":"49122","DOI":"10.1039\/C5RA03316K","volume":"5","author":"Pooja D.","year":"2015","unstructured":"Pooja D.; Kulhari H.; Tunki L.; Chinde S.; Kuncha M.; Grover P.; Rachamalla S.S.; Sistla R.; Nanomedicines for targeted delivery of etoposide to non-small cell lung cancer using transferrin functionalized nanoparticles. RSC Advances  2015,5(61),49122-49131","journal-title":"RSC Advances"},{"key":"ref=121","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1023\/A:1016278302046","volume":"12","author":"Sj\u00f6str\u00f6m B.","year":"1995","unstructured":"Sj\u00f6str\u00f6m B.; Kaplun A.; Talmon Y.; Cabane B.; Structures of nanoparticles prepared from oil-in-water emulsions. Pharm Res  1995,12(1),39-48","journal-title":"Pharm Res"},{"key":"ref=122","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.chemphyslip.2015.09.008","volume":"193","author":"Pooja D.","year":"2015","unstructured":"Pooja D.; Tunki L.; Kulhari H.; Reddy B.B.; Sistla R.; Characterization, biorecognitive activity and stability of WGA grafted lipid nanostructures for the controlled delivery of Rifampicin. Chem Phys Lipids  2015,193,11-17","journal-title":"Chem Phys Lipids"},{"key":"ref=123","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.colsurfb.2014.03.046","volume":"121","author":"Singh B.","year":"2014","unstructured":"Singh B.; Vuddanda P.R.; M R V.; Kumar V.; Saxena P.S.; Singh S.; Cefuroxime axetil loaded solid lipid nanoparticles for enhanced activity against S. aureus biofilm. Colloids Surf B Biointerfaces  2014,121,92-98","journal-title":"Colloids Surf B Biointerfaces"},{"key":"ref=124","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.1007\/s13204-019-01004-6","volume":"9","author":"Patel K.K.","year":"2019","unstructured":"Patel K.K.; Gade S.; Anjum M.M.; Singh S.K.; Maiti P.; Agrawal A.K.; Singh S.; Effect of penetration enhancers and amorphization on transdermal permeation flux of raloxifene-encapsulated solid lipid nanoparticles: An ex vivo study on human skin. Appl Nanosci  2019,9(6),1383-1394","journal-title":"Appl Nanosci"},{"key":"ref=125","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1007\/s13346-011-0023-5","volume":"1","author":"Fonte P.","year":"2011","unstructured":"Fonte P.; Nogueira T.; Gehm C.; Ferreira D.; Sarmento B.; Chitosan- coated solid lipid nanoparticles enhance the oral absorption of insulin. Drug Deliv Transl Res  2011,1(4),299-308","journal-title":"Drug Deliv Transl Res"},{"key":"ref=126","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1248\/cpb.58.650","volume":"58","author":"Singh S.","year":"2010","unstructured":"Singh S.; Dobhal A.K.; Jain A.; Pandit J.K.; Chakraborty S.; Formulation and evaluation of solid lipid nanoparticles of a water soluble drug: Zidovudine. Chem Pharm Bull  2010,58(5),650-655","journal-title":"Chem Pharm Bull"},{"key":"ref=127","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1007\/s10973-009-0127-z","volume":"99","author":"Li Z.","year":"2010","unstructured":"Li Z.; Yu L.; Zheng L.; Geng F.; Studies on crystallinity state of puerarin loaded solid lipid nanoparticles prepared by double emulsion method. J Therm Anal Calorim  2010,99(2),689-693","journal-title":"J Therm Anal Calorim"},{"key":"ref=128","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/S0927-7765(02)00053-X","volume":"27","author":"Garc\u00eda-Fuentes M.","year":"2003","unstructured":"Garc\u00eda-Fuentes M.; Torres D.; Alonso M.J.; Design of lipid nanoparticles for the oral delivery of hydrophilic macromolecules. Colloids Surf B Biointerfaces  2003,27(2-3),159-168","journal-title":"Colloids Surf B Biointerfaces"},{"key":"ref=129","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1016\/j.colsurfb.2013.06.013","volume":"112","author":"Nabi-Meibodi M.","year":"2013","unstructured":"Nabi-Meibodi M.; Vatanara A.; Najafabadi A.R.; Rouini M.R.; Ramezani V.; Gilani K.; Etemadzadeh S.M.H.; Azadmanesh K.; The effective encapsulation of a hydrophobic lipid-insoluble drug in solid lipid nanoparticles using a modified double emulsion solvent evaporation method. Colloids Surf B Biointerfaces  2013,112,408-414","journal-title":"Colloids Surf B Biointerfaces"},{"key":"ref=130","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/j.colsurfb.2018.12.048","volume":"176","author":"Mazur K.L.","year":"2019","unstructured":"Mazur K.L.; Feuser P.E.; Val\u00e9rio A.; Poester Cordeiro A.; de Oliveira C.I.; Assolini J.P.; Pavanelli W.R.; Sayer C.; Ara\u00fajo P.H.H.; Diethyldithiocarbamate loaded in beeswax-copaiba oil nanoparticles obtained by solventless double emulsion technique promote promastigote death in vitro. Colloids Surf B Biointerfaces  2019,176,507-512","journal-title":"Colloids Surf B Biointerfaces"},{"key":"ref=131","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/j.colsurfb.2015.12.033","volume":"140","author":"Becker Peres L.","year":"2016","unstructured":"Becker Peres L.; Becker Peres L.; de Ara\u00fajo P.H.H.; Sayer C.; Solid lipid nanoparticles for encapsulation of hydrophilic drugs by an organic solvent free double emulsion technique. Colloids Surf B Biointerfaces  2016,140,317-323","journal-title":"Colloids Surf B Biointerfaces"},{"key":"ref=132","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/j.ijpharm.2012.05.046","volume":"434","author":"Montenegro L.","year":"2012","unstructured":"Montenegro L.; Sinico C.; Castangia I.; Carbone C.; Puglisi G.; Idebenone-loaded solid lipid nanoparticles for drug delivery to the skin: in vitro evaluation. Int J Pharm  2012,434(1-2),169-174","journal-title":"Int J Pharm"},{"key":"ref=133","doi-asserted-by":"publisher","first-page":"3860","DOI":"10.1021\/la903401g","volume":"26","author":"Roger K.","year":"2010","unstructured":"Roger K.; Cabane B.; Olsson U.; Formation of 10-100 nm size-controlled emulsions through a sub-PIT cycle. Langmuir  2010,26(6),3860-3867","journal-title":"Langmuir"},{"key":"ref=134","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1023\/A:1016121319668","volume":"19","author":"Heurtault B.","year":"2002","unstructured":"Heurtault B.; Saulnier P.; Pech B.; Proust J.E.; Benoit J.P.; A novel phase inversion-based process for the preparation of lipid nanocarriers. Pharm Res  2002,19(6),875-880","journal-title":"Pharm Res"},{"key":"ref=135","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/j.ijpharm.2011.05.076","volume":"415","author":"Montenegro L.","year":"2011","unstructured":"Montenegro L.; Sarpietro M.G.; Ottimo S.; Puglisi G.; Castelli F.; Differential scanning calorimetry studies on sunscreen loaded solid lipid nanoparticles prepared by the phase inversion temperature method. Int J Pharm  2011,415(1-2),301-306","journal-title":"Int J Pharm"},{"key":"ref=136","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1080\/03639045.2019.1569026","volume":"45","author":"Shinde U.A.","year":"2019","unstructured":"Shinde U.A.; Parmar S.J.; Easwaran S.; Metronidazole-loaded nanostructured lipid carriers to improve skin deposition and retention in the treatment of rosacea. Drug Dev Ind Pharm  2019,45(7),1039-1051","journal-title":"Drug Dev Ind Pharm"},{"key":"ref=137","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1080\/02652048.2019.1585982","volume":"36","author":"Gomes G.V.L.","year":"2019","unstructured":"Gomes G.V.L.; Sola M.R.; Rochetti A.L.; Fukumasu H.; Vicente A.A.; Pinho S.C.; \u03b2-carotene and \u03b1-tocopherol coencapsulated in nanostructured lipid carriers of murumuru (Astrocaryum murumuru) butter produced by phase inversion temperature method: Characterisation, dynamic in vitro digestion and cell viability study. J Microencapsul  2019,36(1),43-52","journal-title":"J Microencapsul"},{"key":"ref=138","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1080\/02726351.2017.1295293","volume":"36","author":"Ali H.","year":"2018","unstructured":"Ali H.; Singh S.K.; Preparation and characterization of solid lipid nanoparticles of furosemide using quality by design. Particul Sci Technol  2018,36(6),695-709","journal-title":"Particul Sci Technol"},{"key":"ref=139","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.jconrel.2005.07.023","volume":"108","author":"Charcosset C.","year":"2005","unstructured":"Charcosset C.; El-Harati A.; Fessi H.; Preparation of solid lipid nanoparticles using a membrane contactor. J Control Release  2005,108(1),112-120","journal-title":"J Control Release"},{"key":"ref=140","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.colsurfa.2009.01.003","volume":"338","author":"D\u2019oria C.","year":"2009","unstructured":"D\u2019oria C.; Charcosset C.; Barresi A.A.; Fessi H.; Preparation of solid lipid particles by membrane emulsification\u2014Influence of process parameters. Colloids Surf A Physicochem Eng Asp  2009,338(1-3),114-118","journal-title":"Colloids Surf A Physicochem Eng Asp"},{"key":"ref=141","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1080\/10837450600561182","volume":"11","author":"Ahmed El-Harati A.","year":"2006","unstructured":"Ahmed El-Harati A.; Charcosset C.; Fessi H.; Influence of the formulation for solid lipid nanoparticles prepared with a membrane contactor. Pharm Dev Technol  2006,11(2),153-157","journal-title":"Pharm Dev Technol"},{"key":"ref=142","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1016\/j.ijpharm.2011.12.016","volume":"423","author":"Khayata N.","year":"2012","unstructured":"Khayata N.; Abdelwahed W.; Chehna M.F.; Charcosset C.; Fessi H.; Preparation of vitamin E loaded nanocapsules by the nanoprecipitation method: From laboratory scale to large scale using a membrane contactor. Int J Pharm  2012,423(2),419-427","journal-title":"Int J Pharm"},{"key":"ref=143","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.supflu.2018.08.001","volume":"143","author":"Trucillo P.","year":"2019","unstructured":"Trucillo P.; Campardelli R.; Production of solid lipid nanoparticles with a supercritical fluid assisted process. J Supercrit Fluids  2019,143,16-23","journal-title":"J Supercrit Fluids"},{"key":"ref=144","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1016\/j.addr.2007.04.010","volume":"59","author":"Chattopadhyay P.","year":"2007","unstructured":"Chattopadhyay P.; Shekunov B.; Yim D.; Cipolla D.; Boyd B.; Farr S.; Production of solid lipid nanoparticle suspensions using supercritical fluid extraction of emulsions (SFEE) for pulmonary delivery using the AERx system. Adv Drug Deliv Rev  2007,59(6),444-453","journal-title":"Adv Drug Deliv Rev"},{"key":"ref=145","doi-asserted-by":"publisher","first-page":"3881","DOI":"10.3390\/molecules24213881","volume":"24","author":"Andrade L.N.","year":"2019","unstructured":"Andrade L.N.; Oliveira D.M.L.; Chaud M.V.; Alves T.F.R.; Nery M.; da Silva C.F.; Gonsalves J.K.C.; Nunes R.S.; Corr\u00eaa C.B.; Amaral R.G.; Sanchez-Lopez E.; Souto E.B.; Severino P.; Praziquantel-solid lipid nanoparticles produced by supercritical carbon dioxide extraction: Physicochemical characterization, release profile, and cytotoxicity. Molecules  2019,24(21),3881","journal-title":"Molecules"},{"key":"ref=146","doi-asserted-by":"publisher","first-page":"338","DOI":"10.3109\/10717544.2013.834412","volume":"20","author":"Acevedo-Morantes C.Y.","year":"2013","unstructured":"Acevedo-Morantes C.Y.; Acevedo-Morantes M.T.; Suleiman-Rosado D.; Ram\u00edrez-Vick J.E.; Evaluation of the cytotoxic effect of camptothecin solid lipid nanoparticles on MCF7 cells. Drug Deliv  2013,20(8),338-348","journal-title":"Drug Deliv"},{"key":"ref=147","doi-asserted-by":"publisher","first-page":"78","DOI":"10.3109\/02652040903031279","volume":"27","author":"Battaglia L.","year":"2010","unstructured":"Battaglia L.; Gallarate M.; Cavalli R.; Trotta M.; Solid lipid nanoparticles produced through a coacervation method. J Microencapsul  2010,27(1),78-85","journal-title":"J Microencapsul"},{"key":"ref=148","doi-asserted-by":"publisher","first-page":"1283","DOI":"10.1007\/s00592-019-01403-9","volume":"56","author":"Muntoni E.","year":"2019","unstructured":"Muntoni E.; Marini E.; Ahmadi N.; Milla P.; Gh\u00e8 C.; Bargoni A.; Capucchio M.T.; Biasibetti E.; Battaglia L.; Lipid nanoparticles as vehicles for oral delivery of insulin and insulin analogs: Preliminary ex vivo and in vivo studies. Acta Diabetol  2019,56(12),1283-1292","journal-title":"Acta Diabetol"},{"key":"ref=149","doi-asserted-by":"publisher","first-page":"255","DOI":"10.3390\/ijms19020255","volume":"19","author":"Clemente N.","year":"2018","unstructured":"Clemente N.; Ferrara B.; Gigliotti C.; Boggio E.; Capucchio M.; Biasibetti E.; Schiffer D.; Mellai M.; Annovazzi L.; Cangemi L.; Muntoni E.; Miglio G.; Dianzani U.; Battaglia L.; Dianzani C.; Solid lipid nanoparticles carrying temozolomide for melanoma treatment. Preliminary in vitro and in vivo studies. Int J Mol Sci  2018,19(2),255","journal-title":"Int J Mol Sci"},{"key":"ref=150","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1016\/j.ejpb.2014.10.017","volume":"88","author":"Chirio D.","year":"2014","unstructured":"Chirio D.; Gallarate M.; Peira E.; Battaglia L.; Muntoni E.; Riganti C.; Biasibetti E.; Capucchio M.T.; Valazza A.; Panciani P.; Lanotte M.; Annovazzi L.; Caldera V.; Mellai M.; Filice G.; Corona S.; Schiffer D.; Positive-charged solid lipid nanoparticles as paclitaxel drug delivery system in glioblastoma treatment. Eur J Pharm Biopharm  2014,88(3),746-758","journal-title":"Eur J Pharm Biopharm"},{"key":"ref=151","doi-asserted-by":"publisher","first-page":"639","DOI":"10.2217\/nnm-2016-0380","volume":"12","author":"Battaglia L.","year":"2017","unstructured":"Battaglia L.; Muntoni E.; Chirio D.; Peira E.; Annovazzi L.; Schiffer D.; Mellai M.; Riganti C.; Salaroglio I.C.; Lanotte M.; Panciani P.; Capucchio M.T.; Valazza A.; Biasibetti E.; Gallarate M.; Solid lipid nanoparticles by coacervation loaded with a methotrexate prodrug: Preliminary study for glioma treatment. Nanomedicine  2017,12(6),639-656","journal-title":"Nanomedicine"},{"key":"ref=152","doi-asserted-by":"publisher","first-page":"255102","DOI":"10.1088\/0957-4484\/26\/25\/255102","volume":"26","author":"Battaglia L.","year":"2015","unstructured":"Battaglia L.; Gallarate M.; Peira E.; Chirio D.; Solazzi I.; Giordano S.M.A.; Gigliotti C.L.; Riganti C.; Dianzani C.; Bevacizumab loaded solid lipid nanoparticles prepared by the coacervation technique: Preliminary in vitro studies. Nanotechnology  2015,26(25),255102","journal-title":"Nanotechnology"},{"key":"ref=153","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/S0939-6411(02)00130-3","volume":"55","author":"Schubert M.","year":"2003","unstructured":"Schubert M.; M\u00fcller-Goymann C.C.; Solvent injection as a new approach for manufacturing lipid nanoparticles \u2013 evaluation of the method and process parameters. Eur J Pharm Biopharm  2003,55(1),125-131","journal-title":"Eur J Pharm Biopharm"},{"key":"ref=154","doi-asserted-by":"publisher","first-page":"822","DOI":"10.1016\/j.colsurfb.2012.08.038","volume":"102","author":"Singh A.","year":"2013","unstructured":"Singh A.; Ahmad I.; Akhter S.; Jain G.K.; Iqbal Z.; Talegaonkar S.; Ahmad F.J.; Nanocarrier based formulation of Thymoquinone improves oral delivery: Stability assessment, in vitro and in vivo studies. Colloids Surf B Biointerfaces  2013,102,822-832","journal-title":"Colloids Surf B Biointerfaces"},{"key":"ref=155","doi-asserted-by":"publisher","first-page":"824","DOI":"10.3109\/10837450.2013.836218","volume":"19","author":"Hashem F.M.","year":"2014","unstructured":"Hashem F.M.; Nasr M.; Khairy A.; In vitro cytotoxicity and bioavailability of solid lipid nanoparticles containing tamoxifen citrate. Pharm Dev Technol  2014,19(7),824-832","journal-title":"Pharm Dev Technol"},{"key":"ref=156","first-page":"171","volume":"66","author":"Pandita D.","year":"2011","unstructured":"Pandita D.; Ahuja A.; Lather V.; Dutta T.; Velpandian T.; Khar R.K.; Development, characterization and in vitro assessement of stearylamine-based lipid nanoparticles of paclitaxel. Pharmazie  2011,66(3),171-177","journal-title":"Pharmazie"},{"key":"ref=157","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1016\/j.ijbiomac.2015.08.035","volume":"81","author":"Hansraj G.P.","year":"2015","unstructured":"Hansraj G.P.; Singh S.K.; Kumar P.; Sumatriptan succinate loaded chitosan solid lipid nanoparticles for enhanced anti-migraine potential. Int J Biol Macromol  2015,81,467-476","journal-title":"Int J Biol Macromol"},{"key":"ref=158","doi-asserted-by":"publisher","first-page":"733","DOI":"10.3109\/03639045.2012.694889","volume":"39","author":"Dodiya S.","year":"2013","unstructured":"Dodiya S.; Chavhan S.; Korde A.; Sawant K.K.; Solid lipid nanoparticles and nanosuspension of adefovir dipivoxil for bioavailability improvement: Formulation, characterization, pharmacokinetic and biodistribution studies. Drug Dev Ind Pharm  2013,39(5),733-743","journal-title":"Drug Dev Ind Pharm"},{"key":"ref=159","doi-asserted-by":"publisher","first-page":"191","DOI":"10.3390\/pharmaceutics10040191","volume":"10","author":"Mishra V.","year":"2018","unstructured":"Mishra V.; Bansal K.K.; Verma A.; Yadav N.; Thakur S.; Sudhakar K.; Rosenholm J.M.; Solid lipid nanoparticles: Emerging colloidal nano drug delivery systems. Pharmaceutics  2018,10(4),191","journal-title":"Pharmaceutics"},{"key":"ref=160","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1007\/s00217-022-04176-8","volume":"249","author":"Salminen H.","year":"2023","unstructured":"Salminen H.; Kasapo\u011flu K.N.; \u00d6z\u00e7elik B.; Weiss J.; Stabilization of solid lipid nanoparticles with glycyrrhizin. Eur Food Res Technol  2023,249(3),787-798","journal-title":"Eur Food Res Technol"},{"key":"ref=161","doi-asserted-by":"publisher","first-page":"2202","DOI":"10.3390\/molecules27072202","volume":"27","author":"Musielak E.","year":"2022","unstructured":"Musielak E.; Feliczak-Guzik A.; Nowak I.; Optimization of the conditions of solid lipid nanoparticles (SLN) synthesis. Molecules  2022,27(7),2202","journal-title":"Molecules"},{"key":"ref=162","doi-asserted-by":"publisher","first-page":"104623","DOI":"10.1016\/j.jddst.2023.104623","volume":"86","author":"Assefi M.","year":"2023","unstructured":"Assefi M.; Ataeinaeini M.; Nazari A.; Gholipour A.; Vertiz-Osores J.J.; Melody Calla-V\u00e1squez K.; Zuhair Talib Al-Naqeeb B.; Hussein Jassim K.; Kalajahi H.G.; Yasamineh S.; Dadashpour M.; A state-of-the-art review on solid lipid nanoparticles as a nanovaccines delivery system. J Drug Deliv Sci Technol  2023,86,104623","journal-title":"J Drug Deliv Sci Technol"},{"key":"ref=163","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1016\/j.jsps.2023.05.011","volume":"31","author":"Almawash S.","year":"2023","unstructured":"Almawash S.; Solid lipid nanoparticles, an effective carrier for classical antifungal drugs. Saudi Pharm J  2023,31(7),1167-1180","journal-title":"Saudi Pharm J"},{"key":"ref=164","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1016\/j.jconrel.2023.08.014","volume":"361","author":"Douka S.","year":"2023","unstructured":"Douka S.; Brandenburg L.E.; Casadidio C.; Walther J.; Garcia B.B.M.; Spanholtz J.; Raimo M.; Hennink W.E.; Mastrobattista E.; Caiazzo M.; Lipid nanoparticle- mediated messenger RNA delivery for ex vivo engineering of natural killer cells. J Control Release  2023,361,455-469","journal-title":"J Control Release"},{"key":"ref=165","doi-asserted-by":"publisher","first-page":"104709","DOI":"10.1016\/j.jddst.2023.104709","volume":"86","author":"Akanda M.","year":"2023","unstructured":"Akanda M.; Mithu M.D.S.H.; Douroumis D.; Solid lipid nanoparticles: An effective lipid-based technology for cancer treatment. J Drug Deliv Sci Technol  2023,86,104709","journal-title":"J Drug Deliv Sci Technol"},{"key":"ref=166","doi-asserted-by":"publisher","first-page":"105068","DOI":"10.1016\/j.jddst.2023.105068","volume":"89","author":"Anjum M.M.","year":"2023","unstructured":"Anjum M.M.; Patel K.K.; Bhattacharya S.; Arya D.K.; Pandey P.; Mr V.; Singh S.; Rajinikanth P.S.; Overcoming barriers in cystic fibrosis therapy through inhalational lipid nanoparticles: Challenges and advances. J Drug Deliv Sci Technol  2023,89,105068","journal-title":"J Drug Deliv Sci Technol"},{"key":"ref=167","doi-asserted-by":"publisher","first-page":"101705","DOI":"10.1016\/j.cocis.2023.101705","volume":"66","author":"C\u00e1rdenas M.","year":"2023","unstructured":"C\u00e1rdenas M.; Campbell R.A.; Yanez Arteta M.; Lawrence M.J.; Sebastiani F.; Review of structural design guiding the development of lipid nanoparticles for nucleic acid delivery. Curr Opin Colloid Interface Sci  2023,66,101705","journal-title":"Curr Opin Colloid Interface Sci"},{"key":"ref=168","doi-asserted-by":"publisher","first-page":"103002","DOI":"10.1016\/j.cis.2023.103002","volume":"321","author":"Motsoene F.","year":"2023","unstructured":"Motsoene F.; Abrahamse H.; Dhilip Kumar S.S.; Multifunctional lipid-based nanoparticles for wound healing and antibacterial applications: A review. Adv Colloid Interface Sci  2023,321,103002","journal-title":"Adv Colloid Interface Sci"},{"key":"ref=169","doi-asserted-by":"publisher","first-page":"104616","DOI":"10.1016\/j.jddst.2023.104616","volume":"85","author":"Harish V.","year":"2023","unstructured":"Harish V.; Mohd S.; Tewari D.; Pandey N.K.; Vishwas S.; Babu M.R.; Salkini M.A.; Rehman Z.; Alotaibi J.T.; Alotaibi R.F.; Alrashed F.A.; Prasher P.; Sharma N.; Gupta G.; Jakhmola V.; Singh Y.; Pinto T.J.A.; Paudel K.R.; Mittal N.; Singh T.G.; Arora P.; Dua K.; Singh S.K.; Unravelling the role of solid lipid nanoparticles in drug delivery: Journey from laboratory to clinical trial. J Drug Deliv Sci Technol  2023,85,104616","journal-title":"J Drug Deliv Sci Technol"},{"key":"ref=170","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.jconrel.2023.07.054","volume":"361","author":"El Moukhtari S.H.","year":"2023","unstructured":"El Moukhtari S.H.; Garbayo E.; Amundarain A.; Pascual-Gil S.; Carrasco-Le\u00f3n A.; Prosper F.; Agirre X.; Blanco-Prieto M.J.; Lipid nanoparticles for siRNA delivery in cancer treatment. J Control Release  2023,361,130-146","journal-title":"J Control Release"},{"key":"ref=171","doi-asserted-by":"publisher","first-page":"113491","DOI":"10.1016\/j.colsurfb.2023.113491","volume":"230","author":"Souza I.D.L.","year":"2023","unstructured":"Souza I.D.L.; Saez V.; Mansur C.R.E.; Lipid nanoparticles containing coenzyme Q10 for topical applications: An overview of their characterization. Colloids Surf B Biointerfaces  2023,230,113491","journal-title":"Colloids Surf B Biointerfaces"},{"key":"ref=172","doi-asserted-by":"publisher","first-page":"395","DOI":"10.3109\/10717544.2014.914986","volume":"23","author":"Dudhipala N.","year":"2016","unstructured":"Dudhipala N.; Veerabrahma K.; Candesartan cilexetil loaded solid lipid nanoparticles for oral delivery: Characterization, pharmacokinetic and pharmacodynamic evaluation. Drug Deliv  2016,23(2),395-404","journal-title":"Drug Deliv"},{"key":"ref=173","doi-asserted-by":"publisher","first-page":"1968","DOI":"10.3109\/03639045.2015.1024685","volume":"41","author":"Dudhipala N.","year":"2015","unstructured":"Dudhipala N.; Veerabrahma K.; Pharmacokinetic and pharmacodynamic studies of nisoldipine-loaded solid lipid nanoparticles developed by central composite design. Drug Dev Ind Pharm  2015,41(12),1968-1977","journal-title":"Drug Dev Ind Pharm"},{"key":"ref=174","first-page":"218","volume":"5","author":"Havanoor S.M.","year":"2014","unstructured":"Havanoor S.M.; Manjunath K.; Tippanna Bhagawati S.; Veerapur V.P.; Isradipine loaded solid LIPID nanoparticles for better treatment of hypertension \u2013 Preparation, characterization and in vivo evaluation. Int J Biopharm  2014,5(3),218-224","journal-title":"Int J Biopharm"},{"key":"ref=175","doi-asserted-by":"publisher","first-page":"111073","DOI":"10.1016\/j.colsurfb.2020.111073","volume":"193","author":"Diwan R.","year":"2020","unstructured":"Diwan R.; Ravi P.R.; Pathare N.S.; Aggarwal V.; Pharmacodynamic, pharmacokinetic and physical characterization of cilnidipine loaded solid lipid nanoparticles for oral delivery optimized using the principles of design of experiments. Colloids Surf B Biointerfaces  2020,193,111073","journal-title":"Colloids Surf B Biointerfaces"},{"key":"ref=176","doi-asserted-by":"publisher","first-page":"107","DOI":"10.5530\/ijpi.14.1.14","volume":"14","author":"Salian T.R.","year":"2023","unstructured":"Salian T.R.; Noushida N.; Jaswanth Gowda B.H.; Chakraborty M.; Enumadisetty Srinivasulu S.P.; Ahmed M.G.; Srinivasulu E.; Ahmed M.G.; Cardioprotective potential of resveratrol alone and in combination with piperine on isoproterenol-induced myocardial infarction in rat: Investigation on oral bioavailability of resveratrol. Int J Pharm Investig  2023,14(1),107-116","journal-title":"Int J Pharm Investig"},{"key":"ref=177","author":"Karthika P.","year":"2023; 83-94","unstructured":"Karthika P.; Gowda B.H.J.; Damiri F.; Hemalatha Y.R.; Chandan R.S.; Berrada M.; Nanophytomedicine and Their Applications. Polymer Nanocomposites  2023; 83-94","journal-title":"Polymer Nanocomposites"},{"key":"ref=178","doi-asserted-by":"publisher","first-page":"519","DOI":"10.2174\/0113816128283267240130062600","volume":"30","author":"Paul K.","year":"2024","unstructured":"Paul K.; Gowda B.H.J.; Hani U.; Chandan R.S.; Mohanto S.; Ahmed M.G.; Ashique S.; Kesharwani P.; Traditional uses, phytochemistry, and pharmacological activities of Coleus amboinicus: A comprehensive review. Curr Pharm Des  2024,30(7),519-535","journal-title":"Curr Pharm Des"},{"key":"ref=179","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1556\/1646.10.2018.45","volume":"10","author":"Kumar V.","year":"2018","unstructured":"Kumar V.; Chaudhary H.; Kamboj A.; Development and evaluation of isradipine via rutin-loaded coated solid\u2013lipid nanoparticles. Interv Med Appl Sci  2018,10(4),236-246","journal-title":"Interv Med Appl Sci"},{"key":"ref=180","doi-asserted-by":"publisher","first-page":"117","DOI":"10.7150\/ntno.78102","volume":"7","author":"Dudhipala N.","year":"2023","unstructured":"Dudhipala N.; Ettireddy S.; Youssef A.A.A.; Puchchakayala G.; Development and in vivo pharmacokinetic and pharmacodynamic evaluation of an oral innovative cyclodextrin complexed lipid nanoparticles of irbesartan formulation for enhanced bioavailability. Nanotheranostics  2023,7(1),117-127","journal-title":"Nanotheranostics"},{"key":"ref=181","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1080\/03639040802192822","volume":"35","author":"Bhaskar K.","year":"2009","unstructured":"Bhaskar K.; Mohan C.K.; Lingam M.; Mohan S.J.; Venkateswarlu V.; Rao Y.M.; Bhaskar K.; Anbu J.; Ravichandran V.; Development of SLN and NLC enriched hydrogels for transdermal delivery of nitrendipine: In vitro and in vivo characteristics. Drug Dev Ind Pharm  2009,35(1),98-113","journal-title":"Drug Dev Ind Pharm"},{"key":"ref=182","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.colsurfb.2012.04.027","volume":"97","author":"Chalikwar S.S.","year":"2012","unstructured":"Chalikwar S.S.; Belgamwar V.S.; Talele V.R.; Surana S.J.; Patil M.U.; Formulation and evaluation of Nimodipine-loaded solid lipid nanoparticles delivered via lymphatic transport system. Colloids Surf B Biointerfaces  2012,97,109-116","journal-title":"Colloids Surf B Biointerfaces"},{"key":"ref=183","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1016\/j.nano.2011.08.016","volume":"8","author":"Zhang Z.","year":"2012","unstructured":"Zhang Z.; Gao F.; Bu H.; Xiao J.; Li Y.; Solid lipid nanoparticles loading candesartan cilexetil enhance oral bioavailability: in vitro characteristics and absorption mechanism in rats. Nanomedicine  2012,8(5),740-747","journal-title":"Nanomedicine"},{"key":"ref=184","doi-asserted-by":"publisher","first-page":"344","DOI":"10.22159\/ajpcr.2018.v11i4.23849","volume":"11","author":"Mahajan A.","year":"2018","unstructured":"Mahajan A.; Kaur S.; Kaur S.; Design, formulation, and characterization of stearic acid-based solid lipid nanoparticles of candesartan cilexetil to augment its oral bioavailability. Asian J Pharm Clin Res  2018,11(4),344-350","journal-title":"Asian J Pharm Clin Res"},{"key":"ref=185","doi-asserted-by":"crossref","first-page":"e15012","DOI":"10.1590\/s2175-97902017000115012","volume":"53","author":"Soma D.","year":"2017","unstructured":"Soma D.; Attari Z.; Reddy M.S.; Damodaram A.; Koteshwara K.B.G.; Solid lipid nanoparticles of irbesartan: Preparation, characterization, optimization and pharmacokinetic studies.  Braz J Pharm Sci  2017,53(1),e15012","journal-title":"Braz J Pharm Sci"},{"key":"ref=186","doi-asserted-by":"publisher","first-page":"e0203405","DOI":"10.1371\/journal.pone.0203405","volume":"13","author":"El-Say K.M.","year":"2018","unstructured":"El-Say K.M.; Hosny K.M.; Optimization of carvedilol solid lipid nanoparticles: An approach to control the release and enhance the oral bioavailability on rabbits. PLoS One  2018,13(8),e0203405","journal-title":"PLoS One"},{"key":"ref=187","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.colsurfb.2018.02.011","volume":"165","author":"Pandya N.T.","year":"2018","unstructured":"Pandya N.T.; Jani P.; Vanza J.; Tandel H.; Solid lipid nanoparticles as an efficient drug delivery system of olmesartan medoxomil for the treatment of hypertension. Colloids Surf B Biointerfaces  2018,165,37-44","journal-title":"Colloids Surf B Biointerfaces"},{"key":"ref=188","doi-asserted-by":"publisher","first-page":"2057","DOI":"10.4314\/tjpr.v16i9.4","volume":"16","author":"Kipriye Z.","year":"2017","unstructured":"Kipriye Z.; \u015eenel B.; Yenilmez E.; Preparation and evaluation of carvedilol-loaded solid lipid nanoparticles for targeted drug delivery. Trop J Pharm Res  2017,16(9),2057","journal-title":"Trop J Pharm Res"},{"key":"ref=189","doi-asserted-by":"publisher","first-page":"475","DOI":"10.3109\/10837450.2013.795169","volume":"19","author":"Shah M.K.","year":"2014","unstructured":"Shah M.K.; Madan P.; Lin S.; Preparation, in vitro evaluation and statistical optimization of carvedilol-loaded solid lipid nanoparticles for lymphatic absorption via oral administration. Pharm Dev Technol  2014,19(4),475-485","journal-title":"Pharm Dev Technol"},{"key":"ref=190","doi-asserted-by":"publisher","first-page":"30","DOI":"10.3109\/02652048.2015.1094532","volume":"33","author":"\u00dcst\u00fcnda\u011f-Okur N.","year":"2016","unstructured":"\u00dcst\u00fcnda\u011f-Okur N.; Yurdasiper A.; G\u00fcndo\u011fdu E.; Homan G\u00f6k\u00e7e E.; Modification of solid lipid nanoparticles loaded with nebivolol hydrochloride for improvement of oral bioavailability in treatment of hypertension: Polyethylene glycol versus chitosan oligosaccharide lactate. J Microencapsul  2016,33(1),30-42","journal-title":"J Microencapsul"},{"key":"ref=191","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1080\/03639045.2016.1275666","volume":"43","author":"Nooli M.","year":"2017","unstructured":"Nooli M.; Chella N.; Kulhari H.; Shastri N.R.; Sistla R.; Solid lipid nanoparticles as vesicles for oral delivery of olmesartan medoxomil: Formulation, optimization and in vivo evaluation. Drug Dev Ind Pharm  2017,43(4),611-617","journal-title":"Drug Dev Ind Pharm"},{"key":"ref=192","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1208\/s12249-020-01711-2","volume":"21","author":"He Y.","year":"2020","unstructured":"He Y.; Zhan C.; Pi C.; Zuo Y.; Yang S.; Hu M.; Bai Y.; Zhao L.; Wei Y.; Enhanced oral bioavailability of felodipine from solid lipid nanoparticles prepared through effervescent dispersion technique. AAPS PharmSciTech  2020,21(5),170","journal-title":"AAPS PharmSciTech"},{"key":"ref=193","doi-asserted-by":"publisher","first-page":"90","DOI":"10.22159\/ijap.2023v15i6.48971","volume":"15","author":"U. G.","year":"2023","unstructured":"U. G.; Formulation and evaluation of nanoparticle drug delivery system for treatment of hypertension. Int J Appl Pharm  2023,15(6),90-97","journal-title":"Int J Appl Pharm"},{"key":"ref=194","doi-asserted-by":"publisher","first-page":"216","DOI":"10.4103\/0975-1483.83765","volume":"3","author":"Ekambaram P.","year":"2011","unstructured":"Ekambaram P.; Abdul Hasan Sathali A.; Formulation and evaluation of solid lipid nanoparticles of ramipril. J Young Pharm  2011,3(3),216-220","journal-title":"J Young Pharm"},{"key":"ref=195","doi-asserted-by":"publisher","first-page":"22","DOI":"10.2174\/1872210517666221019102543","volume":"18","author":"Dugad T.","year":"2024","unstructured":"Dugad T.; Kanugo A.; Design optimization and evaluation of solid lipid nanoparticles of azelnidipine for the treatment of hypertension. Recent Pat Nanotechnol  2024,18(1),22-32","journal-title":"Recent Pat Nanotechnol"},{"key":"ref=196","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1080\/10611860600888850","volume":"14","author":"Manjunath K.","year":"2006","unstructured":"Manjunath K.; Venkateswarlu V.; Pharmacokinetics, tissue distribution and bioavailability of nitrendipine solid lipid nanoparticles after intravenous and intraduodenal administration. J Drug Target  2006,14(9),632-645","journal-title":"J Drug Target"},{"key":"ref=197","doi-asserted-by":"publisher","first-page":"120","DOI":"10.22159\/ajpcr.2018.v11i9.24666","volume":"11","author":"Pn R.","year":"2018","unstructured":"Pn R.; N D.; Formulation, development, and characterisation of cilnidipine loaded solid lipid nanoparticles. Asian J Pharm Clin Res  2018,11(9),120","journal-title":"Asian J Pharm Clin Res"},{"key":"ref=198","doi-asserted-by":"publisher","first-page":"1353","DOI":"10.1208\/s12249-015-0440-8","volume":"17","author":"Aboud H.M.","year":"2016","unstructured":"Aboud H.M.; El komy M.H.; Ali A.A.; El Menshawe S.F.; Abd Elbary A.; Development, optimization, and evaluation of carvedilol-loaded solid lipid nanoparticles for intranasal drug delivery. AAPS PharmSciTech  2016,17(6),1353-1365","journal-title":"AAPS PharmSciTech"},{"key":"ref=199","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1016\/j.addr.2003.12.002","volume":"56","author":"Wissing S.A.","year":"2004","unstructured":"Wissing S.A.; Kayser O.; M\u00fcller R.H.; Solid lipid nanoparticles for parenteral drug delivery. Adv Drug Deliv Rev  2004,56(9),1257-1272","journal-title":"Adv Drug Deliv Rev"},{"key":"ref=200","first-page":"80","volume":"2","author":"Ekambaram P.","year":"2012","unstructured":"Ekambaram P.; Abdul A.; Sathali H.; Priyanka K.; Solid lipid nanoparticles: A review. Sci Revs Chem Commun  2012,2(1),80-102","journal-title":"Sci Revs Chem Commun"},{"key":"ref=201","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.ijpharm.2007.05.061","volume":"345","author":"Shah K.","year":"2007","unstructured":"Shah K.; Date A.; Joshi M.; Patravale V.; Solid lipid nanoparticles (SLN) of tretinoin: Potential in topical delivery. Int J Pharm  2007,345(1-2),163-171","journal-title":"Int J Pharm"},{"key":"ref=202","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1016\/j.ijpharm.2011.05.044","volume":"415","author":"Tiwari R.","year":"2011","unstructured":"Tiwari R.; Pathak K.; Nanostructured lipid carrier versus solid lipid nanoparticles of simvastatin: Comparative analysis of characteristics, pharmacokinetics and tissue uptake. Int J Pharm  2011,415(1-2),232-243","journal-title":"Int J Pharm"},{"key":"ref=203","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/B978-0-08-100963-5.00006-9","author":"Nazemi P.","year":"2017","unstructured":"Nazemi P.; Razavi M.;  Lipid-based nanobiomaterials  2017,125-133","journal-title":"Lipid-based nanobiomaterials"},{"key":"ref=204","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1016\/B978-0-323-46152-8.00017-2","author":"Bayraktar O.","year":"2017","unstructured":"Bayraktar O.; Erdogan I.; K\u00f6se M.D.; Kalmaz G.; Nanocarriers for plant-derived natural compounds. NanoStructures for antimicrobial therapy: Nanostructures in therapeutic medicine series  2017,395-412","journal-title":"NanoStructures for antimicrobial therapy: Nanostructures in therapeutic medicine series"},{"key":"ref=205","doi-asserted-by":"publisher","first-page":"114485","DOI":"10.1016\/j.addr.2022.114485","volume":"189","author":"Correia A.C.","year":"2022","unstructured":"Correia A.C.; Monteiro A.R.; Silva R.; Moreira J.N.; Sousa Lobo J.M.; Silva A.C.; Lipid nanoparticles strategies to modify pharmacokinetics of central nervous system targeting drugs: Crossing or circumventing the blood\u2013brain barrier (BBB) to manage neurological disorders. Adv Drug Deliv Rev  2022,189,114485","journal-title":"Adv Drug Deliv Rev"}],"container-title":["Current Pharmaceutical Design"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.eurekaselect.com\/article\/download?doi=10.2174\/0113816128337166241219081400","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/240301\/article","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/article\/download?doi=10.2174\/0113816128337166241219081400","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T13:11:23Z","timestamp":1750943483000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurekaselect.com\/240301\/article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":205,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["LiveAll1"],"URL":"https:\/\/doi.org\/10.2174\/0113816128337166241219081400","relation":{},"ISSN":["1381-6128"],"issn-type":[{"value":"1381-6128","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2024-07-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}