{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T19:27:29Z","timestamp":1785353249216,"version":"3.55.0"},"reference-count":0,"publisher":"Bentham Science Publishers Ltd.","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["RRCT"],"published-print":{"date-parts":[[2026,6,12]]},"abstract":"<jats:sec>\n                    <jats:title>Abstract:<\/jats:title>\n                    <jats:p>Dietary fibers, and more specifically water-soluble fibers, beneficially affect human\nhealth. Guar gum and its enzymatic product, partially hydrolyzed guar gum (PHGG), are among the\nmost studied dietary fibers in humans. Altogether, they can be described as \u201cguar fiber\u201d. We performed\na narrative review of the literature on guar fiber, namely guar gum and its partially hydrolyzed\nproduct, and their impact on human health, with a special focus on the gastrointestinal tract,\ngut microbiota, gut-brain axis, and liver steatosis. Accordingly, a literature search was conducted\nusing the following keywords and combinations: guar fiber, guar gum, partially hydrolyzed guar\ngum, disorders of gut-brain interaction, gut-liver axis, and gut microbiota. Guar gum and its derivative,\nPHGG, show promising effects in gastrointestinal disorders, such as constipation and diarrhea.\nInterestingly, they can modulate the gut microbiota, with promising implications for the gut-brain\naxis and disorders of gut-brain interaction, such as irritable bowel syndrome. There are also interesting,\nalbeit preliminary, results regarding their use in fatty liver disease. Thus, dietary fibers such as\nguar gum and, more importantly, its hydrolyzed product, show promising and better-documented\neffects on the health of the gastrointestinal tract and other organs and systems of the human body.\nHowever, the latter evidence still requires clinical confirmation of preclinical findings. Overall, the\nreviewed data vary in quality and maturity across different outcome domains.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2174\/0115748871483178260603111726","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T06:30:36Z","timestamp":1781677836000},"update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Guar Gum, Partially Hydrolyzed Guar Gum, and Human Gut Health: A Narrative Review"],"prefix":"10.2174","volume":"21","author":[{"given":"Emidio","family":"Scarpellini","sequence":"first","affiliation":[{"name":"Internal and Nutritional Unit, \u201cMadonna del soccorso\u201d General Hospital, San Benedetto del Tronto, Italy"},{"name":"Polytechnics University of Marche, Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Roselli","sequence":"additional","affiliation":[{"name":"Internal and Nutritional Unit, \u201cMadonna del soccorso\u201d General Hospital, San Benedetto del Tronto, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marialaura","family":"Scarcella","sequence":"additional","affiliation":[{"name":"Anesthesia, Intensive Care and Nutritional Science, 'Santa Maria' Hospital, Terni and Nutritional Residency Program, Perugia University, Perugia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla","family":"Tedesco","sequence":"additional","affiliation":[{"name":"Internal and Nutritional Unit, \u201cMadonna del soccorso\u201d General Hospital, San Benedetto del Tronto, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serena","family":"di Bu\u00f2","sequence":"additional","affiliation":[{"name":"Internal and Nutritional Unit, \u201cMadonna del soccorso\u201d General Hospital, San Benedetto del Tronto, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Di Giovanni","sequence":"additional","affiliation":[{"name":"School of Medicine, University \u201cMagna Graecia\u201d, Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Luisa","family":"Gambardella","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University \u201cMagna Graecia\u201d, Catanzaro, Italy"},{"name":"Center for Chronic Liver Diseases, \u201cRenato Dulbecco\u201d University Hospital, Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe Guido Maria","family":"Scarlata","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University \u201cMagna Graecia\u201d, Catanzaro, Italy"},{"name":"Center for Chronic Liver Diseases, \u201cRenato Dulbecco\u201d University Hospital, Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Tack","sequence":"additional","affiliation":[{"name":"Translational Research in Gastrointestinal Disorders (T.A.R.G.I.D.), Gasthuisberg University Hospital, KU Leuven, Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludovico","family":"Abenavoli","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University \u201cMagna Graecia\u201d, Catanzaro, Italy"},{"name":"Center for Chronic Liver Diseases, \u201cRenato Dulbecco\u201d University Hospital, Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","container-title":["Reviews on Recent Clinical Trials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.eurekaselect.com\/article\/download?doi=10.2174\/0115748871483178260603111726","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/255135\/article","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/article\/download?doi=10.2174\/0115748871483178260603111726","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T06:31:02Z","timestamp":1781677862000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurekaselect.com\/255135\/article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,12]]},"references-count":0,"alternative-id":["LiveAll1"],"URL":"https:\/\/doi.org\/10.2174\/0115748871483178260603111726","relation":{},"ISSN":["1574-8871"],"issn-type":[{"value":"1574-8871","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6,12]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Double blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2026-02-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-29","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}