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Our aim is to\nunderstand the patterns of symptoms, underlying causes, and treatment approaches used for thyroid\nnodules. By doing so, the intention is to distill the essential aspects, compile Professor Xu\nZhiyin's clinical insights, and investigate his scholarly perspectives.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Methods:<\/jats:title>\n<jats:p>Professor Xu Zhiyin's clinical diagnoses and treatments spanning from 2009 to 2019\nwere entered into Microsoft Excel. Subsequently, the collected data was imported into the Medcase\nV5.2 system to facilitate data mining. Various techniques, such as frequency-based method,\nassociation rule analysis, and clustering, including a decentralized system clustering approach,\nwere employed on a set of 346 cases involving patients with thyroid nodules that conformed\nto the specified criteria. The primary focus was on extracting insights regarding symptoms\nand the underlying causes from the medical records. By integrating these findings with\nProfessor Xu Zhiyin's clinical expertise, we examined and summarized the outcomes of the data\nmining process.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results:<\/jats:title>\n<jats:p>The fundamental prescriptions were successfully extracted using the techniques for\nmining across multiple dimensions. Utilizing the scattered grouping of these prescriptions and\nwith reference to the cluster analysis of the frequency-linked system, the fundamental prescriptions\nproposed by Professor Xu Zhiyin for addressing thyroid nodules encompass the following\ningredients: Glycyrrhiza uralensis Fisch, Cortex Moutan, Paeoniae radix rubra, Curcuma longa\nL., Radix Curcumae, persica seed, Citri Reticulatae Viride Pericarpium, Pinellia ternata, Spica\nPrunellae, Ostreae concha, Gleditsia sinensis spine, Tuckahoe and Radix Codonopsis.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>The fundamental prescriptions were acquired using the frequency approach, association\nrule technique, k-means clustering approach, and systematic clustering approach. The\nresearch findings corroborate one another, demonstrating that Professor Xu Zhiyin's approach to\ndistinguishing and treating thyroid nodules is embodied in distinct prescriptions tailored to specific\ndiseases.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/0118715303258346231101190843","type":"journal-article","created":{"date-parts":[[2023,11,30]],"date-time":"2023-11-30T06:43:50Z","timestamp":1701326630000},"page":"1081-1089","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A Multi-dimensional Data Mining-based Study on the Prescriptions\nDeveloped by Professor Xu Zhiyin in Treating Thyroid Nodules"],"prefix":"10.2174","volume":"24","author":[{"given":"Hai-Jian","family":"Sun","sequence":"first","affiliation":[{"name":"Department of General Surgery, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Man","family":"Wei","sequence":"additional","affiliation":[{"name":"Nanjing University of Chinese Medicine, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Lu","sequence":"additional","affiliation":[{"name":"Nanjing University of Chinese Medicine, Nanjing 210023, China"},{"name":"Nanjing Medical Data Mining Center, Nanjing\n210029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Zhu","sequence":"additional","affiliation":[{"name":"Nanjing University of Chinese Medicine, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","reference":[{"key":"ref=1","doi-asserted-by":"publisher","first-page":"13S","DOI":"10.2967\/jnumed.120.246025","volume":"62","author":"Bernet V.J.","year":"2021","unstructured":"Bernet V.J.; Chindris A.M.; Update on the evaluation of thyroid nodules. 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