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There is evidence from genetic\nstudies exploring the relation between migraine and RAS-related genes and from clinical trials\nevaluating the efficacy of Angiotensin II Type 1 (AT1) receptor antagonists and angiotensin\nconverting enzyme inhibitors in migraine prophylaxis. RAS seems to play a role in the\npathophysiology of migraine, but more direct evidence is still missing.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/0929866527666200129160136","type":"journal-article","created":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T13:58:01Z","timestamp":1580306281000},"page":"512-519","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Renin-Angiotensin-Aldosterone System and Migraine: A Systematic Review of Human Studies"],"prefix":"10.2174","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4269-4966","authenticated-orcid":true,"given":"Karina L\u00facia Moreira","family":"Sassi","sequence":"first","affiliation":[{"name":"Neuropsychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9814-8649","authenticated-orcid":true,"given":"La\u00eds Bhering","family":"Martins","sequence":"additional","affiliation":[{"name":"Neuropsychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2811-7924","authenticated-orcid":true,"given":"Aline Silva","family":"de Miranda","sequence":"additional","affiliation":[{"name":"Department of Morphology, Institute of Biological Sciences, The Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9621-5422","authenticated-orcid":true,"given":"Antonio Lucio","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Neuropsychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","reference":[{"key":"ref=1","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1056\/NEJMcp1605502","volume":"377","author":"Charles A.","year":"2017","unstructured":"Charles A.; Migraine. 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