{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T06:59:36Z","timestamp":1763535576250},"reference-count":0,"publisher":"Bentham Science Publishers Ltd.","issue":"39","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["CMC"],"published-print":{"date-parts":[[2019,1,17]]},"abstract":"<jats:sec>\n<jats:title \/>\n<jats:p>A number of biological and clinical characteristics typical of late life depression\n(LLD) have been suggested by recent research findings. The close association of LLD with\ncognitive impairment is now well documented and evidenced. However, it is still not clear\nwhether it is depression that leads to cognitive decline, and in more severe cases, to dementia.\nThe work presented in this review article suggests that depression and dementia frequently\nand strongly copresent, even if the causality remains largely opaque.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/0929867323666160902152829","type":"journal-article","created":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T15:28:29Z","timestamp":1542727709000},"page":"5389-5394","update-policy":"http:\/\/dx.doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Late-life Depression and Alzheimer Disease: A Potential Synergy of the Underlying Mechanisms"],"prefix":"10.2174","volume":"25","author":[{"given":"Jerzy","family":"Leszek","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Wroclaw Medical University, Pasteura 10, Str.,50-368 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"El\u017cbieta","family":"Trypka","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Wroclaw Medical University, Pasteura 10, Str.,50-368 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Euphrosyni","family":"Koutsouraki","sequence":"additional","affiliation":[{"name":"Medical School, Aristotle University, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios","family":"Michmizos","sequence":"additional","affiliation":[{"name":"Medical School, Aristotle University, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nagendra Sastry","family":"Yarla","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Bioinformatics, Institute of Science, GITAM University, Visakhapatnam, Andhra Pradesh, 530045, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vadim V.","family":"Tarasov","sequence":"additional","affiliation":[{"name":"Sechenov First Moscow State Medical University, 119991, Moscow, Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghulam Md","family":"Ashraf","sequence":"additional","affiliation":[{"name":"King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gjumrakch","family":"Aliev","sequence":"additional","affiliation":[{"name":"Sechenov First Moscow State Medical University, 119991, Moscow, Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","container-title":["Current Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/eurekaselect.com\/article\/download\/145306","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/145306\/article","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eurekaselect.com\/article\/download\/145306","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,25]],"date-time":"2020-12-25T09:48:37Z","timestamp":1608889717000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurekaselect.com\/145306\/article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,17]]},"references-count":0,"journal-issue":{"issue":"39","published-print":{"date-parts":[[2019,1,17]]}},"alternative-id":["LiveAll1"],"URL":"https:\/\/doi.org\/10.2174\/0929867323666160902152829","relation":{},"ISSN":["0929-8673"],"issn-type":[{"value":"0929-8673","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1,17]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2016-04-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-06-25","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-07-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}