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In general, endothelial dysfunction is linked to poor cardiovascular\nprognosis and different methods, both invasive and non-invasive, have been developed\nfor its evaluation. Ultrasound evaluation of flow mediated dilatation of the branchial\nartery is the most commonly used method to assessed endothelial function while intracoronary\nadministration of vasoactive agents may be also be used to test directly endothelial properties\nof the coronary vasculature. Endothelial dysfunction has also been the subject of therapeutic\ninterventions. This review article summarizes the knowledge about evaluation of endothelial\nfunction in acute coronary syndromes and stable coronary artery disease and demonstrates\nthe current therapeutic approaches against endothelial dysfunction.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/0929867326666190830103219","type":"journal-article","created":{"date-parts":[[2019,8,31]],"date-time":"2019-08-31T04:05:41Z","timestamp":1567224341000},"page":"1052-1080","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Coronary Artery Disease and Endothelial Dysfunction: Novel Diagnostic and Therapeutic Approaches"],"prefix":"10.2174","volume":"27","author":[{"given":"Evangelos","family":"Oikonomou","sequence":"first","affiliation":[{"name":"Department of Cardiology, \u2018Hippokration\u2019 General Hospital, National and Kapodistrian University of Athens, School of Medicine, 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