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In\nthis regard, the effects of NPs on the reproductive system of animals and humankind\nhave been a matter of concern. In this article, we will review the potential reproductive\ntoxicity of various types of NPs, including carbon nanomaterials, dendrimers, quantum\ndots, silica, gold, and magnetic nanoparticles, reported in the literature. We also mention\nsome notable cases where NPs have elicited beneficial effects on the reproductive system.\nThis review provides extensive insight into the effects of various NPs on sperm and\novum and the outcomes of their passage through blood-testis and placental barriers and\naccumulation in the reproductive organs.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/0929867331666230815101141","type":"journal-article","created":{"date-parts":[[2023,8,15]],"date-time":"2023-08-15T12:57:23Z","timestamp":1692104243000},"page":"1507-1552","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Reproductive Toxicity of Nanoparticles: A Comprehensive Review"],"prefix":"10.2174","volume":"32","author":[{"given":"Elaheh","family":"Mohammadi","sequence":"first","affiliation":[{"name":"Students Research Committee, Faculty of Pharmacy, Kerman University of Medical Sciences, Kerman,\nIran"},{"name":"Toxicology Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University\nof Medical Sciences, Ahvaz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Behzad","family":"Behnam","sequence":"additional","affiliation":[{"name":"Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman\nUniversity of Medical Sciences, Kerman, Iran"},{"name":"Herbal and Traditional Medicines Research Center,\nKerman University of Medical Sciences, Kerman, Iran"},{"name":"Extremophile and Productive Microorganisms Research\nCenter, Kerman University of Medical Science, Kerman, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahad","family":"Mokhtarzadeh","sequence":"additional","affiliation":[{"name":"Immunology Research Center,\nTabriz University of Medical Sciences, Tabriz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramin","family":"Rezaee","sequence":"additional","affiliation":[{"name":"International UNESCO Center for Health-Related Basic\nSciences and Human Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad,\nIran"},{"name":"Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ardavan","family":"Abiri","sequence":"additional","affiliation":[{"name":"Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT06520, USA"},{"name":"Integrated\nGraduate Program in Physical and Engineering Biology, Yale University, New Haven, CT06520,\nUSA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Ramezani","sequence":"additional","affiliation":[{"name":"Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical\nSciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Giesy","sequence":"additional","affiliation":[{"name":"Toxicology Centre, Department of Veterinary Biomedical Sciences, University\nof Saskatchewan, 10 Campus Drive, Saskatoon, SKS7N 5B4, Canada"},{"name":"Department of Environmental\nSciences, Baylor University, Waco, 76798-7266, USA"},{"name":"Department of Integrated Biology, Michigan State\nUniversity, East Lansing, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amirhossein","family":"Sahebkar","sequence":"additional","affiliation":[{"name":"Biotechnology Research Center, Pharmaceutical Technology Institute,\nMashhad University of Medical Sciences, Mashhad, Iran"},{"name":"Applied Biomedical Research Center, Mashhad\nUniversity of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","reference":[{"key":"ref=1","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1038\/s41565-021-00866-8","volume":"16","author":"Kirtane A.R.","year":"2021","unstructured":"Kirtane A.R.; Verma M.; Karandikar P.; Furin J.; Langer R.; Traverso G.; Nanotechnology approaches for global infectious diseases. 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