{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:04:59Z","timestamp":1787317499529,"version":"build-2736575974"},"reference-count":17,"publisher":"Bentham Science Publishers Ltd.","issue":"1","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["CCHTS"],"published-print":{"date-parts":[[2019,5,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Gallstone formation is a pathological process of mineralization in the human\nbody. Determination of the morphology and ultrastructure of gallstones holds the key to\nunderstanding the pathophysiology of gallbladder disease. Synchrotron radiation phase-contrast Xray\nmicrotomography is a novel technology, which is designed for comprehensive analysis of\ngallstone ultrastructure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Nine human gallstones were obtained from the Department of Pathology,\nQingpu branch of Zhongshan Hospital Affiliated to Fudan University (China), and scanned by\nsynchrotron radiation \u00b5CT (SR \u00b5CT). The imaging data generated by SR \u00b5CT scan were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The three-dimensional ultrastructure of human gallstones corresponding to their\ncholesterol and bile pigment composition was determined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The ultrastructure of gallstones exhibits considerable diversity and complexity. The\nsynchrotron radiation phase-contrast X-ray microtomography is a valuable tool for in-depth study\nof human gallstones.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2174\/1386207322666190222122007","type":"journal-article","created":{"date-parts":[[2019,2,25]],"date-time":"2019-02-25T06:33:01Z","timestamp":1551076381000},"page":"13-17","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Ultrastructural Analysis of Human Gallstones using Synchrotron Radiation \u00b5CT"],"prefix":"10.2174","volume":"22","author":[{"given":"Weixin","family":"Chen","sequence":"first","affiliation":[{"name":"Department of General Surgery, The Second Affiliated Hospital of Soochow University, No.1055, Sanxiang Rd, Suzhou 215004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riming","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Central Laboratory, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai, Shandong Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suo","family":"Tao","sequence":"additional","affiliation":[{"name":"The General Surgery Department of Zhongshan Hospital, The General Surgery Institute, Fudan University, 180 Fenglin Road, Xuhui, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weixing","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Affiliated Zhongshan Hospital of Fudan University, Qinpu Branch, Qingpu, Shanghai, 201700, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weihong","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Affiliated Zhongshan Hospital of Fudan University, Qinpu Branch, Qingpu, Shanghai, 201700, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Song","sequence":"additional","affiliation":[{"name":"The General Surgery Department of Zhongshan Hospital, The General Surgery Institute, Fudan University, 180 Fenglin Road, Xuhui, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanhua","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Affiliated Zhongshan Hospital of Fudan University, Qinpu Branch, Qingpu, Shanghai, 201700, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chungen","family":"Xing","sequence":"additional","affiliation":[{"name":"Department of General Surgery, The Second Affiliated Hospital of Soochow University, No.1055, Sanxiang Rd, Suzhou 215004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","reference":[{"key":"ref=1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.clinre.2011.01.009","volume":"35","author":"Van Erpecum K.J.","year":"2011","unstructured":"Van Erpecum KJ. 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