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Although various medications are applied in treating endocrine and metabolic illnesses,\nnumerous obstacles exist to overcome. Nucleic acid nanomaterials are novel materials synthesized and engineered in\nthe laboratory. In this case, Nucleic acids are employed as non-biological nanomaterials instead of serving as carriers\nof genetic information in live cells. Because of their high biocompatibility and editability, nucleic acid nanomaterials\nwere frequently employed in disease diagnosis and therapy. 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