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We show evidence of the cytotoxic effect of blue scorpion venom in a cellular model of Glioblastoma multiforme.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>We show evidence of the cytotoxic effect of blue scorpion venom in a cellular model of Glioblastoma multiforme.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Our results demonstrate that 50 \u03bcg\/ml of scorpion venom is capable to diminish the viability of Glioblastoma populations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>It is possible that the action mechanism could be associated with a loss of membrane integrity. Additionally, some metalloproteinases as MMP2 and MMP9 may also participate in the potential action mechanism.<\/jats:p><\/jats:sec>","DOI":"10.2174\/1389201021666200717092207","type":"journal-article","created":{"date-parts":[[2020,7,17]],"date-time":"2020-07-17T21:16:18Z","timestamp":1595020578000},"page":"636-645","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Cytotoxic Effects of Blue Scorpion Venom (Rhopalurus junceus) in a Glioblastoma Cell Line Model"],"prefix":"10.2174","volume":"22","author":[{"given":"Laura A.","family":"Lozano-Trujillo","sequence":"first","affiliation":[{"name":"Departamento de Biologia, Facultad de Ciencias, Universidad del Tolima, 730006299, Ibague,Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana K.","family":"Garz\u00f3n-Perdomo","sequence":"additional","affiliation":[{"name":"Departamento de Biologia, Facultad de Ciencias, Universidad del Tolima, 730006299, Ibague,Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea C.R.","family":"Vargas","sequence":"additional","affiliation":[{"name":"Departamento de Biologia, Facultad de Ciencias, Universidad del Tolima, 730006299, Ibague,Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina M.","family":"de los Reyes","sequence":"additional","affiliation":[{"name":"Departamento de Biologia, Facultad de Ciencias, Universidad del Tolima, 730006299, Ibague,Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4612-3236","authenticated-orcid":true,"given":"Marco F.","family":"Avila-Rodriguez","sequence":"additional","affiliation":[{"name":"Departamento de Ciencias Clinicas, Facultad de Ciencias de la Salud, Universidad del Tolima, 730006299, Ibague,Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia T.G.","family":"Gay","sequence":"additional","affiliation":[{"name":"Cuban Neuroscience Center, La Habana,Cuba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9189-0402","authenticated-orcid":true,"given":"Liliana F.","family":"Turner","sequence":"additional","affiliation":[{"name":"Departamento de Biologia, Facultad de Ciencias, Universidad del Tolima, 730006299, Ibague,Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","reference":[{"key":"ref=1","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3322\/caac.21551","volume":"69","author":"Siegel R.L.","year":"2019","unstructured":"Siegel R.L.; Miller K.D.; Jemal A.; Cancer statistics, 2019. 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