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In\naddition to the pain caused by the tumor itself, patients also experience discomfort from the\ntreatment, such as surgery, chemotherapy, radiation therapy, and the diagnostic procedures. The\nmajority of today's pain therapies rely on opioid analgesics, which have not been shown to be\neffective. The adverse effects of opioids and their addictive properties call for the development of\ninnovative treatment techniques. Nanotechnology offers answers to the issues raised above, which\nare related to the utilization of more conventional modes of therapy. These nanotechnology-based\nnanotherapeutics reduce the systemic toxicity, offering outstanding selectiveness and prolonged\nrelease of the analgesic drugs at the target site. Thus, these reduce cancer-induced pain in the\npatients. In this article, we will explain the mechanism behind the most common types of pain that\nare caused by cancer, including neuropathic, somatic, and visceral pain. In addition, a\ncomprehensive discussion is held on the use of various nanotherapeutics as analgesic drug carriers,\nas well as on their impacts and the potential opportunities that lie ahead in the field of cancer pain\ntreatment.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1389201024666230123150856","type":"journal-article","created":{"date-parts":[[2023,2,3]],"date-time":"2023-02-03T15:14:31Z","timestamp":1675437271000},"page":"1365-1375","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Cancer-induced Pain Management by Nanotechnology-based Approach"],"prefix":"10.2174","volume":"24","author":[{"given":"Chanakya Nath","family":"Kundu","sequence":"first","affiliation":[{"name":"Cancer Biology Division, KIIT School of Biotechnology, KIIT (Deemed to be University), Campus-11, Patia,\nBhubaneswar, 751024, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Somya Ranjan","family":"Dash","sequence":"additional","affiliation":[{"name":"Cancer Biology Division, KIIT School of Biotechnology, KIIT (Deemed to be University), Campus-11, Patia,\nBhubaneswar, 751024, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"ref=1","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.jcrpr.2017.07.001","volume":"4","author":"Hassanpour S.H.","year":"2017","unstructured":"Hassanpour S.H.; Dehghani M.; Review of cancer from perspective of molecular. 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