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Foods high in flavonoids, such as green tea, chocolate, blueberries, and\nother fruits and vegetables, have ameliorated symptoms of cognitive impairment, Alzheimer's\ndisease, and dementia in several animal models. As a result of their ability to prevent neuronal\ndeath generated by neurotoxic chemicals such as free radicals and \u03b2-amyloid proteins. Furthermore,\nflavonoids are also effective in slowing the evolution of clinical signs of neurodegenerative\nillnesses. In addition, flavonoids can improve lipid profiles by preventing the oxidation of\nlow-density lipoproteins, and these antioxidant capabilities are responsible for their therapeutic\nimpacts. Finally, the potential of flavonoids to induce vasodilation and control apoptotic processes\nin the endothelium is another way in which they benefit the cardiovascular system. This\nreview aims to offer up-to-date information on categorizing these compounds, their primary\nmethods of action in the human body, and their positive impacts on the management of neurodegenerative\ndiseases, cardiovascular disorders, and other life-threatening diseases.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1389201024666230314101654","type":"journal-article","created":{"date-parts":[[2023,3,15]],"date-time":"2023-03-15T05:29:42Z","timestamp":1678858182000},"page":"1740-1773","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["An Overview of Dietary Flavonoids as a Nutraceutical Nanoformulation\nApproach to Life-threatening Diseases"],"prefix":"10.2174","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1503-2745","authenticated-orcid":true,"given":"Sonia","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Institute of Pharmaceutical Research, GLA University, Mathura, U.P-201406, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8792-7180","authenticated-orcid":true,"given":"Ashima","family":"Ahuja","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Institute of Pharmaceutical Research, GLA University, Mathura, U.P-201406, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Himanshu","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Computer Engineering and Applications, GLA University, Mathura, U.P-201406, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pratik","family":"Maheshwari","sequence":"additional","affiliation":[{"name":"Fresenius\nKabi India Pvt Ltd, Ghaziabad, U.P., India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"ref=1","first-page":"296","volume":"19","author":"Burak M.","year":"1999","unstructured":"Burak M.; Imen Y.; Flavonoids and their antioxidant properties. 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