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It was demonstrated that aPDT\nhas low local toxicity, can speed up dental therapy, and is cost-effective. Several photosensitizers\n(PSs) are available for each type of light source which did not induce any damage to the patient\nand are safe. In recent years, significant advances have been made in aPDT as a non-invasive\ntreatment method, especially in treating infections and cancers. Besides, aPDT can be perfectly\ncombined with other treatments. Hence, this survey focused on the effectiveness and mechanism\nof aPDT of periodontitis by using lasers and the most frequently used antimicrobial PSs such as\nmethylene blue (MB), toluidine blue ortho (TBO), indocyanine green (ICG), malachite green\n(MG) (Triarylmethanes), erythrosine dyes (ERY) (Xanthenes dyes), rose bengal (RB) (Xanthenes\ndyes), eosin-Y (Xanthenes dyes), radachlorin group and curcumin. The aPDT with these PSs can\nreduce pathogenic bacterial loads in periodontitis. Therefore, it is clear that there is a bright future\nfor using aPDT to fight microorganisms causing periodontitis.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1389201024666230720104516","type":"journal-article","created":{"date-parts":[[2023,7,21]],"date-time":"2023-07-21T06:25:11Z","timestamp":1689920711000},"page":"1209-1229","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Effects of Antimicrobial Photosensitizers of Photodynamic Therapy (PDT)\nto Treat Periodontitis"],"prefix":"10.2174","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8380-6883","authenticated-orcid":true,"given":"Samaneh","family":"Bourbour","sequence":"first","affiliation":[{"name":"Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atieh","family":"Darbandi","sequence":"additional","affiliation":[{"name":"Molecular\nMicrobiology Research Center, Shahed University, Tehran, Iran"},{"name":"Department of Microbiology, School of Medicine,\nIran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narjess","family":"Bostanghadiri","sequence":"additional","affiliation":[{"name":"Department of Microbiology, School of Medicine,\nIran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roya","family":"Ghanavati","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Behbahan Faculty of Medical Sciences,\nBehbahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Behrouz","family":"Taheri","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, School of Allied Medical Sciences, Ahvaz Jundishapur\nUniversity of Medical Sciences, Ahvaz, Iran"},{"name":"Infectious and Tropical Diseases Research Center, Health Research\nInstitute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbas","family":"Bahador","sequence":"additional","affiliation":[{"name":"Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","reference":[{"key":"ref=1","doi-asserted-by":"publisher","first-page":"e006","DOI":"10.1590\/1807-3107bor-2018.vol32.0006","volume":"32","author":"Llanos A.H.","year":"2018","unstructured":"Llanos A.H.; Silva C.G.B.; Ichimura K.T.; Rebeis E.S.; Giudicissi M.; Romano M.M.; Saraiva L.; Impact of aggressive periodontitis and chronic periodontitis on oral health-related quality of life. 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