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It has better compliance among\nthe pediatric and geriatric groups owing to its ease of administration.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Objective:<\/jats:title>\n<jats:p>The polymeric wafer dissolves quickly in the oral cavity and is highly effective for a targeted\nlocal effect in buccal-specific ailments. It is a safe, effective, and versatile drug delivery carrier for a\nrange of drugs used to treat a plethora of oral cavity-specific ailments that inflict common people, like\nthrush, canker sores, periodontal disease, benign oral cavity tumors, buccal neoplasm, and malignancies.\nThis review paper focuses thoroughly on the present state of the art in mouth-dissolving wafer\ntechnology for buccal drug delivery and targeting. Moreover, we have also addressed present-time limitations\nassociated with wafer technology to aid researchers in future developments in the arena of buccal\ndrug delivery.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>This dynamic novel formulation has tremendous future implications for designing drug\ndelivery systems to target pernicious ailments and diseases specific to the buccal mucosa. In a nutshell,\nthis review paper aims to summarize the present state of the art in buccal targeted drug delivery.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1567201820666221128152010","type":"journal-article","created":{"date-parts":[[2022,11,29]],"date-time":"2022-11-29T05:53:42Z","timestamp":1669701222000},"page":"339-359","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Current Drug Delivery Strategies for Buccal Cavity Ailments using Mouth\nDissolving Wafer Technology: A Comprehensive Review on the Present\nState of the Art"],"prefix":"10.2174","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1204-6968","authenticated-orcid":true,"given":"Bani Kumar","family":"Jana","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical sciences, Dibrugarh University, Dibrugarh-786004, Assam, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6407-3722","authenticated-orcid":true,"given":"Mohini","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical sciences, Dibrugarh University, Dibrugarh-786004, Assam, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2804-1141","authenticated-orcid":true,"given":"Rajat Subhra","family":"Dutta","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical sciences, Dibrugarh University, Dibrugarh-786004, Assam, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5731-0435","authenticated-orcid":true,"given":"Bhaskar","family":"Mazumder","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical sciences, Dibrugarh University, Dibrugarh-786004, Assam, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","reference":[{"key":"ref=1","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/S0140-6736(19)31146-8","volume":"394","author":"Peres M.A.","year":"2019","unstructured":"Peres M.A.; Macpherson L.M.D.; Weyant R.J.; Daly B.; Venturelli R.; Mathur M.R.; Listl S.; Celeste R.K.; Guarnizo-Herre\u00f1o C.C.; Kearns C.; Benzian H.; Allison P.; Watt R.G.; Oral diseases: A global public health challenge. 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