{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T15:44:47Z","timestamp":1757778287650},"reference-count":0,"publisher":"Bentham Science Publishers Ltd.","issue":"1","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["CAR"],"published-print":{"date-parts":[[2017,12,21]]},"abstract":"<jats:sec>\n<jats:title \/>\n<jats:p>Objectives: Based on an analysis of the potential consequences of disclosing AD suspicions from\nrespective research and using the research ethical principle of non-maleficence, the authors of this paper argue\nfor the thesis that the benefits of early AD detection in research outweigh the risk of potential adverse effects\nonly in cases where studies are conducted with symptomatic people actively seeking for support, e.g. as they\nutilize the services of memory clinics.\n<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusion:<\/jats:title>\n<jats:p> In the case of non-symptomatic volunteers, the result of the risk-benefit-assessment seems to be\nless distinctive. Given that disclosing results can, at least initially, cause severe distress and harm and taking\ninto account that research examinations have a significantly increased risk of producing false-positive findings,\nwe suggest to make use of a research-ethical \u201cprincple of caution\u201d that supports a restrictive disclosure policy\nfor the second group of potential study participants. This differentiated view on the benefits of disclosed findings\nin AD research is reflected in recommendations for the set-up of return of result processes.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1567205014666170908101237","type":"journal-article","created":{"date-parts":[[2017,12,21]],"date-time":"2017-12-21T14:43:59Z","timestamp":1513867439000},"page":"28-37","update-policy":"http:\/\/dx.doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["The Ambivalence of Early Diagnosis \u2013 Returning Results in Current Alzheimer Research"],"prefix":"10.2174","volume":"15","author":[{"given":"Pia","family":"Erdmann","sequence":"first","affiliation":[{"name":"Faculty of Theology, Systematic Theology, University of Greifswald, Greifswald, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Langanke","sequence":"additional","affiliation":[{"name":"Faculty of Theology, Systematic Theology, University of Greifswald, Greifswald, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","container-title":["Current Alzheimer Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/eurekaselect.com\/article\/download\/155434","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/155434\/article","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eurekaselect.com\/article\/download\/155434","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,29]],"date-time":"2020-12-29T16:00:14Z","timestamp":1609257614000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurekaselect.com\/155434\/article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,21]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12,21]]}},"alternative-id":["LiveAll1"],"URL":"https:\/\/doi.org\/10.2174\/1567205014666170908101237","relation":{},"ISSN":["1567-2050"],"issn-type":[{"value":"1567-2050","type":"print"}],"subject":[],"published":{"date-parts":[[2017,12,21]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2017-03-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-07-07","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-08-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-12-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}