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Genetic\npolymorphisms may explain some of the variances in shared phenomenology between the diagnoses, the\ninstance, when the conditions arise comorbidly, the order in which they are detected that may depend on\nindividual cognitive and physical reserves, as well as the medical history and individual vulnerability.\nThis hypothesis is biologically sound but has not been systematically investigated to date. The current\nreview highlights how genetic variations are involved in the development of both AD and MDD, and the\nrisk conferred by these variations on the expression of these two disorders comorbidly is an important\nconsideration for future studies of pathoaetiological mechanisms and in the stratification of study samples\nfor randomised controlled trials.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2174\/1567205017666200217104114","type":"journal-article","created":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T06:58:36Z","timestamp":1581922716000},"page":"16-28","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["Depression in Dementia or Dementia in Depression? 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