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The regeneration of the liver can be carried out using umbilical cord blood stem cells which have various advantages over other stem cell types used in liver transplantation. UCB-derived stem cells lack tumorigenicity, have karyotype stability and high immunomodulatory, low risk of graft versus host disease (GVHD), low risk of transmitting somatic mutations or viral infections, and low immunogenicity. They are readily available and their collection is safe and painless. This review focuses on recent development and modern trends in the use of umbilical cord stem cells for the regeneration of liver fibrosis.<\/jats:p><\/jats:sec>","DOI":"10.2174\/1568026620666200220122536","type":"journal-article","created":{"date-parts":[[2020,2,20]],"date-time":"2020-02-20T15:23:14Z","timestamp":1582212194000},"page":"219-232","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Therapeutic Potential of Umbilical Cord Stem Cells for Liver Regeneration"],"prefix":"10.2174","volume":"15","author":[{"given":"Ifrah","family":"Anwar","sequence":"first","affiliation":[{"name":"Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5495-805X","authenticated-orcid":true,"given":"Usman A.","family":"Ashfaq","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeeshan","family":"Shokat","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"ref=1","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1126\/science.282.5391.1145","volume":"282","author":"Thomson J.A.","year":"1998","unstructured":"Thomson J.A.; Itskovitz-Eldor J.; Shapiro S.S.; Waknitz M.A.; Swiergiel J.J.; Marshall V.S.; Jones J.M.; Embryonic stem cell lines derived from human blastocysts. 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