{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T22:23:06Z","timestamp":1778883786830,"version":"3.51.4"},"reference-count":158,"publisher":"Bentham Science Publishers Ltd.","issue":"1","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["CVP"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n<jats:title>:<\/jats:title>\n<jats:p>Arterial stiffness (AS) describes the rigidity of the arterial walls. Epidemiological\nstudies have shown that increased AS is an independent predictive marker of cardiovascular (CV)\nmorbidity and mortality in both pregnant and non-pregnant women. Preeclampsia (PE), a form of\npregnancy-induced hypertension, affects approximately 5% of pregnancies worldwide. Preeclamptic\nwomen have a higher risk of CV disease (CVD), mainly because PE damages the heart\u2019s ability\nto relax between contractions. Different pharmacological approaches for the prevention of PE have\nbeen tested in clinical trials (e.g. aspirin, enoxaparin, metformin, pravastatin, and sildenafil citrate).\nIn current clinical practice, only low-dose aspirin is used for PE pharmacoprevention. However,\nlow-dose aspirin does not prevent term PE, which is the most common form of PE. Compromised\nvascular integrity precedes the onset of PE and therefore, AS assessment may constitute a promising\npredictive marker of PE. Several non-invasive techniques have been developed to assess AS.\nCompared with normotensive pregnancies, both carotid-femoral pulse wave velocity (cfPWV) and\naugmentation index (AIx) are increased in PE. In view of simplicity, reliability, and reproducibility,\nthere is an interest in oscillometric AS measurements in pregnancies complicated by PE.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1570161119666211006114258","type":"journal-article","created":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T05:59:01Z","timestamp":1633586341000},"page":"52-61","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Arterial Stiffness as a Cardiovascular Risk Factor for the Development of Preeclampsia and Pharmacopreventive Options"],"prefix":"10.2174","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5466-1846","authenticated-orcid":true,"given":"Christos","family":"Anthoulakis","sequence":"first","affiliation":[{"name":"First Department of Obstetrics &amp; Gynecology, \u201cPapageorgiou\u201d General Hospital, Aristotle University of Thessaloniki,\nThessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Apostolos","family":"Mamopoulos","sequence":"additional","affiliation":[{"name":"Third Department of Obstetrics &amp; Gynecology, Hippokration General Hospital, Aristotle\nUniversity of Thessaloniki, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Rousso","sequence":"additional","affiliation":[{"name":"Third Department of Obstetrics &amp; Gynecology, Hippokration General Hospital, Aristotle\nUniversity of Thessaloniki, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asterios","family":"Karagiannis","sequence":"additional","affiliation":[{"name":"Second Propaedeutic Department of Internal Medicine, Hippokration\nGeneral Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Apostolos","family":"Athanasiadis","sequence":"additional","affiliation":[{"name":"Third Department of Obstetrics &amp; Gynecology, Hippokration General Hospital, Aristotle\nUniversity of Thessaloniki, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grigoris","family":"Grimbizis","sequence":"additional","affiliation":[{"name":"First Department of Obstetrics &amp; Gynecology, \u201cPapageorgiou\u201d General Hospital, Aristotle University of Thessaloniki,\nThessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasilios","family":"Athyros","sequence":"additional","affiliation":[{"name":"Second Propaedeutic Department of Internal Medicine, Hippokration\nGeneral Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"ref=1","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1093\/qjmed\/95.2.67","volume":"95","author":"Mackenzie I.S.","year":"2002","unstructured":"Mackenzie I.S.; Wilkinson I.B.; Cockcroft J.R.; Assessment of arterial stiffness in clinical practice. QJM 2002,95(2),67-74","journal-title":"QJM"},{"key":"ref=2","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1161\/CIRCULATIONAHA.109.886655","volume":"121","author":"Mitchell G.F.","year":"2010","unstructured":"Mitchell G.F.; Hwang S-J.; Vasan R.S.; Larson M.G.; Pencina M.J.; Hamburg N.M.; Vita J.A.; Levy D.; Benjamin E.J.; Arterial stiffness and cardiovascular events: The Framingham Heart Study. Circulation 2010,121(4),505-511","journal-title":"Circulation"},{"key":"ref=3","doi-asserted-by":"publisher","first-page":"e50","DOI":"10.1016\/j.jacc.2010.09.001","volume":"56","author":"Greenland P.","year":"2010","unstructured":"Greenland P.; Alpert J.S.; Beller G.A.; Benjamin E.J.; Budoff M.J.; Fayad Z.A.; Foster E.; Hlatky M.A.; Hodgson J.M.; Kushner F.G.; Lauer M.S.; Shaw L.J.; Smith S.C.; Taylor A.J.; Weintraub W.S.; Wenger N.K.; Jacobs A.K.; Smith S.C.; Anderson J.L.; Albert N.; Buller C.E.; Creager M.A.; Ettinger S.M.; Guyton R.A.; Halperin J.L.; Hochman J.S.; Kushner F.G.; Nishimura R.; Ohman E.M.; Page R.L.; Stevenson W.G.; Tarkington L.G.; Yancy C.W.; 2010 ACCF\/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: A report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2010,56(25),e50-e103","journal-title":"J Am Coll Cardiol"},{"key":"ref=4","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1001\/jama.281.7.634","volume":"281","author":"Chae C.U.","year":"1999","unstructured":"Chae C.U.; Pfeffer M.A.; Glynn R.J.; Mitchell G.F.; Taylor J.O.; Hennekens C.H.; Increased pulse pressure and risk of heart failure in the elderly. JAMA 1999,281(7),634-639","journal-title":"JAMA"},{"key":"ref=5","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1177\/0003319715594291","volume":"66","author":"Doumas M.","year":"2015","unstructured":"Doumas M.; Papademetriou V.; Athyros V.; Karagiannis A.; Arterial stiffness and emerging biomarkers: Still a long journey to go. Angiology 2015,66(10),901-903","journal-title":"Angiology"},{"key":"ref=6","doi-asserted-by":"publisher","first-page":"627","DOI":"10.2174\/15701611113119990131","volume":"12","author":"Katsiki N.","year":"2014","unstructured":"Katsiki N.; Athyros V.G.; Karagiannis A.; Mikhailidis D.P.; Characteristics other than the diagnostic criteria associated with metabolic syndrome: An overview. Curr Vasc Pharmacol 2014,12(4),627-641","journal-title":"Curr Vasc Pharmacol"},{"key":"ref=7","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1681\/ASN.2019020117","volume":"30","author":"Zanoli L.","year":"2019","unstructured":"Zanoli L.; Lentini P.; Briet M.; Castellino P.; House A.A.; London G.M.; Malatino L.; McCullough P.A.; Mikhailidis D.P.; Boutouyrie P.; Arterial stiffness in the heart disease of CKD. J Am Soc Nephrol 2019,30(6),918-928","journal-title":"J Am Soc Nephrol"},{"key":"ref=8","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/j.preghy.2018.05.004","volume":"13","author":"Brown M.A.","year":"2018","unstructured":"Brown M.A.; Magee L.A.; Kenny L.C.; Karumanchi S.A.; McCarthy F.P.; Saito S.; Hall D.R.; Warren C.E.; Adoyi G.; Ishaku S.; The hypertensive disorders of pregnancy: ISSHP classification, diagnosis","journal-title":"Pregnancy Hypertens"},{"key":"ref=9","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1016\/S1701-2163(15)30533-8","volume":"36","author":"Magee L.A.","year":"2014","unstructured":"Magee L.A.; Pels A.; Helewa M.; Rey E.; von Dadelszen P.; Diagnosis, evaluation, and management of the hypertensive disorders of pregnancy: Executive summary. J Obstet Gynaecol Can 2014,36(7),575-576","journal-title":"J Obstet Gynaecol Can"},{"key":"ref=10","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1097\/HJH.0b013e32834e4b0f","volume":"30","author":"Hausvater A.","year":"2012","unstructured":"Hausvater A.; Giannone T.; Sandoval Y-H.G.; Doonan R.J.; Antonopoulos C.N.; Matsoukis I.L.; Petridou E.T.; Daskalopoulou S.S.; The association between preeclampsia and arterial stiffness. J Hypertens 2012,30(1),17-33","journal-title":"J Hypertens"},{"key":"ref=11","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1080\/10641963.2016.1254227","volume":"39","author":"Namugowa A.","year":"2017","unstructured":"Namugowa A.; Iputo J.; Wandabwa J.; Meeme A.; Buga G.A.B.; Comparison of arterial stiffness in preeclamptic and normotensive pregnant women from a semi-rural region of South Africa. Clin Exp Hypertens 2017,39(3),277-283","journal-title":"Clin Exp Hypertens"},{"key":"ref=12","doi-asserted-by":"publisher","first-page":"720683","DOI":"10.1155\/2015\/720683","volume":"2015","author":"Torrado J.","year":"2015","unstructured":"Torrado J.; Farro I.; Z\u00f3calo Y.; Farro F.; Sosa C.; Scasso S.; Alonso J.; Bia D.; Preeclampsia is associated with increased central aortic pressure, elastic arteries stiffness and wave reflections, and resting and recruitable endothelial dysfunction. Int J Hypertens 2015,2015,720683","journal-title":"Int J Hypertens"},{"key":"ref=13","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1186\/s12884-020-03374-0","volume":"20","author":"Kim S.","year":"2020","unstructured":"Kim S.; Lim H.J.; Kim J.R.; Oh K.J.; Hong J.S.; Suh J.W.; Longitudinal change in arterial stiffness after delivery in women with preeclampsia and normotension: A prospective cohort study. BMC Pregnancy Childbirth 2020,20(1),685","journal-title":"BMC Pregnancy Childbirth"},{"key":"ref=14","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1097\/HJH.0000000000001664","volume":"36","author":"Osman M.W.","year":"2018","unstructured":"Osman M.W.; Nath M.; Breslin E.; Khalil A.; Webb D.R.; Robinson T.G.; Mousa H.A.; Association between arterial stiffness and wave reflection with subsequent development of placental-mediated diseases during pregnancy: Findings of a systematic review and meta-analysis. J Hypertens 2018,36(5),1005-1014","journal-title":"J Hypertens"},{"key":"ref=15","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1161\/HYPERTENSIONAHA.109.130898","volume":"53","author":"Robb A.O.","year":"2009","unstructured":"Robb A.O.; Mills N.L.; Din J.N.; Smith I.B.; Paterson F.; Newby D.E.; Denison F.C.; Influence of the menstrual cycle, pregnancy, and preeclampsia on arterial stiffness. Hypertension 2009,53(6),952-958","journal-title":"Hypertension"},{"key":"ref=16","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1097\/00004872-200501000-00025","volume":"23","author":"Elvan-Ta\u015fpinar A.","year":"2005","unstructured":"Elvan-Ta\u015fpinar A.; Bots M.L.; Franx A.; Bruinse H.W.; Engelbert R.H.H.; Stiffness of the arterial wall, joints and skin in women with a history of pre-eclampsia. J Hypertens 2005,23(1),147-151","journal-title":"J Hypertens"},{"key":"ref=17","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1097\/01.hjh.0000217859.27864.19","volume":"24","author":"Lampinen K.H.","year":"2006","unstructured":"Lampinen K.H.; R\u00f6nnback M.; Kaaja R.J.; Groop P-H.; Impaired vascular dilatation in women with a history of pre-eclampsia. J Hypertens 2006,24(4),751-756","journal-title":"J Hypertens"},{"key":"ref=18","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1081\/PRG-200059871","volume":"24","author":"R\u00f6nnback M.","year":"2005","unstructured":"R\u00f6nnback M.; Lampinen K.; Groop P-H.; Kaaja R.; Pulse wave reflection in currently and previously preeclamptic women. Hypertens Pregnancy 2005,24(2),171-180","journal-title":"Hypertens Pregnancy"},{"key":"ref=19","doi-asserted-by":"publisher","first-page":"544","DOI":"10.3109\/10641960902890176","volume":"31","author":"P\u00e0ez O.","year":"2009","unstructured":"P\u00e0ez O.; Alfie J.; Gorosito M.; Puleio P.; de Maria M.; Prieto N.; Majul C.; Parallel decrease in arterial distensibility and in endothelium-dependent dilatation in young women with a history of pre-eclampsia. Clin Exp Hypertens 2009,31(7),544-552","journal-title":"Clin Exp Hypertens"},{"key":"ref=20","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1016\/j.ajog.2006.01.104","volume":"195","author":"Oyama-Kato M.","year":"2006","unstructured":"Oyama-Kato M.; Ohmichi M.; Takahashi K.; Suzuki S.; Henmi N.; Yokoyama Y.; Kurachi H.; Change in pulse wave velocity throughout normal pregnancy and its value in predicting pregnancy-induced hypertension: A longitudinal study. Am J Obstet Gynecol 2006,195(2),464-469","journal-title":"Am J Obstet Gynecol"},{"key":"ref=21","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.preghy.2013.01.006","volume":"3","author":"Hale S.A.","year":"2013","unstructured":"Hale S.A.; Badger G.J.; McBride C.; Magness R.; Bernstein I.M.; Prepregnancy vascular dysfunction in women who subsequently develop hypertension during pregnancy. Pregnancy Hypertens 2013,3(2),140-145","journal-title":"Pregnancy Hypertens"},{"key":"ref=22","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1136\/bmj.39366.416817.BE","volume":"335","author":"Magnussen E.B.","year":"2007","unstructured":"Magnussen E.B.; Vatten L.J.; Lund-Nilsen T.I.; Salvesen K.A.; Davey Smith G.; Romundstad P.R.; Prepregnancy cardiovascular risk factors as predictors of pre-eclampsia: Population based cohort study. BMJ 2007,335(7627),978","journal-title":"BMJ"},{"key":"ref=23","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1016\/j.jacc.2019.07.012","volume":"74","author":"Chirinos J.A.","year":"2019","unstructured":"Chirinos J.A.; Segers P.; Hughes T.; Townsend R.; Large-artery stiffness in health and disease: JACC State-of-the-Art Review. J Am Coll Cardiol 2019,74(9),1237-1263","journal-title":"J Am Coll Cardiol"},{"key":"ref=24","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1001\/2012.jama.10503","volume":"308","author":"Kaess B.M.","year":"2012","unstructured":"Kaess B.M.; Rong J.; Larson M.G.; Hamburg N.M.; Vita J.A.; Levy D.; Benjamin E.J.; Vasan R.S.; Mitchell G.F.; Aortic stiffness, blood pressure progression, and incident hypertension. JAMA 2012,308(9),875-881","journal-title":"JAMA"},{"key":"ref=25","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1161\/HYPERTENSIONAHA.110.157339","volume":"56","author":"Chirinos J.A.","year":"2010","unstructured":"Chirinos J.A.; Segers P.; Noninvasive evaluation of left ventricular afterload: part 2: Arterial pressure-flow and pressure-volume relations in humans. Hypertension 2010,56(4),563-570","journal-title":"Hypertension"},{"key":"ref=26","doi-asserted-by":"publisher","first-page":"64","DOI":"10.2174\/1874192401610010064","volume":"10","author":"Katsiki N.","year":"2016","unstructured":"Katsiki N.; Kollari E.; Dardas S.; Dardas P.; Haidich A.B.; Athyros V.G.; Karagiannis A.; Is there an association between carotid-femoral pulse wave velocity and coronary heart disease in patients with coronary artery disease: A pilot study. Open Cardiovasc Med J 2016,10,64-68","journal-title":"Open Cardiovasc Med J"},{"key":"ref=27","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1161\/01.HYP.0000168052.00426.65","volume":"46","author":"O\u2019Rourke M.F.","year":"2005","unstructured":"O\u2019Rourke M.F.; Safar M.E.; Relationship between aortic stiffening and microvascular disease in brain and kidney: Cause and logic of therapy. Hypertension 2005,46(1),200-204","journal-title":"Hypertension"},{"key":"ref=28","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1161\/01.CIR.80.1.78","volume":"80","author":"Hirai T.","year":"1989","unstructured":"Hirai T.; Sasayama S.; Kawasaki T.; Yagi S.; Stiffness of systemic arteries in patients with myocardial infarction. A noninvasive method to predict severity of coronary atherosclerosis. Circulation 1989,80(1),78-86","journal-title":"Circulation"},{"key":"ref=29","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1161\/01.STR.32.2.454","volume":"32","author":"van Popele N.M.","year":"2001","unstructured":"van Popele N.M.; Grobbee D.E.; Bots M.L.; Asmar R.; Topouchian J.; Reneman R.S.; Hoeks A.P.; van der Kuip D.A.; Hofman A.; Witteman J.C.; Association between arterial stiffness and atherosclerosis: The Rotterdam Study. Stroke 2001,32(2),454-460","journal-title":"Stroke"},{"key":"ref=30","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1161\/01.CIR.68.1.50","volume":"68","author":"Avolio A.P.","year":"1983","unstructured":"Avolio A.P.; Chen S.G.; Wang R.P.; Zhang C.L.; Li M.F.; O\u2019Rourke M.F.; Effects of aging on changing arterial compliance and left ventricular load in a northern Chinese urban community. Circulation 1983,68(1),50-58","journal-title":"Circulation"},{"key":"ref=31","year":"2011","unstructured":"Theoretical, experimental and clinical principles McDonald\u2019s blood flow in arteries2011","journal-title":"Theoretical, experimental and clinical principles"},{"key":"ref=32","doi-asserted-by":"publisher","first-page":"1328","DOI":"10.1161\/HYPERTENSIONAHA.109.137653","volume":"54","author":"Cecelja M.","year":"2009","unstructured":"Cecelja M.; Chowienczyk P.; Dissociation of aortic pulse wave velocity with risk factors for cardiovascular disease other than hypertension: A systematic review. Hypertension 2009,54(6),1328-1336","journal-title":"Hypertension"},{"key":"ref=33","doi-asserted-by":"publisher","first-page":"1202","DOI":"10.1161\/hc1002.105135","volume":"105","author":"Benetos A.","year":"2002","unstructured":"Benetos A.; Adamopoulos C.; Bureau J.M.; Temmar M.; Labat C.; Bean K.; Thomas F.; Pannier B.; Asmar R.; Zureik M.; Safar M.; Guize L.; Determinants of accelerated progression of arterial stiffness in normotensive subjects and in treated hypertensive subjects over a 6-year period. Circulation 2002,105(10),1202-1207","journal-title":"Circulation"},{"key":"ref=34","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1161\/HYPERTENSIONAHA.110.150896","volume":"56","author":"McEniery C.M.","year":"2010","unstructured":"McEniery C.M.; Spratt M.; Munnery M.; Yarnell J.; Lowe G.D.; Rumley A.; Gallacher J.; Ben-Shlomo Y.; Cockcroft J.R.; Wilkinson I.B.; An analysis of prospective risk factors for aortic stiffness in men: 20-year follow-up from the Caerphilly prospective study. Hypertension 2010,56(1),36-43","journal-title":"Hypertension"},{"key":"ref=35","doi-asserted-by":"publisher","first-page":"1480","DOI":"10.1016\/j.jacc.2010.09.079","volume":"57","author":"Cecelja M.","year":"2011","unstructured":"Cecelja M.; Jiang B.; Bevan L.; Frost M.L.; Spector T.D.; Chowienczyk P.J.; Arterial stiffening relates to arterial calcification but not to noncalcified atheroma in women. A twin study. J Am Coll Cardiol 2011,57(13),1480-1486","journal-title":"J Am Coll Cardiol"},{"key":"ref=36","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1161\/HYPERTENSIONAHA.111.00024","volume":"61","author":"Cecelja M.","year":"2013","unstructured":"Cecelja M.; Hussain T.; Greil G.; Botnar R.; Preston R.; Moayyeri A.; Spector T.D.; Chowienczyk P.; Multimodality imaging of subclinical aortic atherosclerosis: Relation of aortic stiffness to calcification and plaque in female twins. Hypertension 2013,61(3),609-614","journal-title":"Hypertension"},{"key":"ref=37","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1161\/01.STR.0000251796.38954.b2","volume":"38","author":"Paini A.","year":"2007","unstructured":"Paini A.; Boutouyrie P.; Calvet D.; Zidi M.; Agabiti-Rosei E.; Laurent S.; Multiaxial mechanical characteristics of carotid plaque: Analysis by multiarray echotracking system. Stroke 2007,38(1),117-123","journal-title":"Stroke"},{"key":"ref=38","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1161\/01.ATV.18.4.535","volume":"18","author":"Blacher J.","year":"1998","unstructured":"Blacher J.; Demuth K.; Guerin A.P.; Safar M.E.; Moatti N.; London G.M.; Influence of biochemical alterations on arterial stiffness in patients with end-stage renal disease. Arterioscler Thromb Vasc Biol 1998,18(4),535-541","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref=39","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1177\/028418518702800215","volume":"28","author":"Christensen T.","year":"1987","unstructured":"Christensen T.; Neubauer B.; Arterial wall stiffness in insulin-dependent diabetes mellitus. An in vivo study. Acta Radiol 1987,28(2),207-208","journal-title":"Acta Radiol"},{"key":"ref=40","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1161\/01.ATV.16.8.978","volume":"16","author":"Lehto S.","year":"1996","unstructured":"Lehto S.; Niskanen L.; Suhonen M.; R\u00f6nnemaa T.; Laakso M.; Medial artery calcification. A neglected harbinger of cardiovascular complications in non-insulin-dependent diabetes mellitus. Arterioscler Thromb Vasc Biol 1996,16(8),978-983","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref=41","doi-asserted-by":"publisher","first-page":"2239","DOI":"10.1111\/jch.14089","volume":"22","author":"Loutradis C.","year":"2020","unstructured":"Loutradis C.; Schoina M.; Dimitroulas T.; Doumas M.; Garyfallos A.; Karagiannis A.; Papagianni A.; Sarafidis P.; Comparison of ambulatory central hemodynamics and arterial stiffness in patients with diabetic and non-diabetic CKD. J Clin Hypertens (Greenwich) 2020,22(12),2239-2249","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"ref=42","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1038\/s41440-020-0525-y","volume":"44","author":"Schoina M.","year":"2021","unstructured":"Schoina M.; Loutradis C.; Memmos E.; Dimitroulas T.; Pagkopoulou E.; Doumas M.; Karagiannis A.; Garyfallos A.; Papagianni A.; Sarafidis P.; Microcirculatory function deteriorates with advancing stages of chronic kidney disease independently of arterial stiffness and atherosclerosis. Hypertens Res 2021,44(2),179-187","journal-title":"Hypertens Res"},{"key":"ref=43","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1161\/01.HYP.0000054978.86286.92","volume":"41","author":"Zureik M.","year":"2003","unstructured":"Zureik M.; Bureau J.M.; Temmar M.; Adamopoulos C.; Courbon D.; Bean K.; Touboul P.J.; Benetos A.; Ducimeti\u00e8re P.; Echogenic carotid plaques are associated with aortic arterial stiffness in subjects with subclinical carotid atherosclerosis. Hypertension 2003,41(3),519-527","journal-title":"Hypertension"},{"key":"ref=44","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.artres.2012.09.001","volume":"7","author":"Cecelja M.","year":"2012","unstructured":"Cecelja M.; Chowienczyk P.; Arterial stiffening: Causes and consequences. Artery Res 2012,7,22-27","journal-title":"Artery Res"},{"key":"ref=45","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1161\/01.HYP.0000237669.64066.c5","volume":"48","author":"Stewart A.D.","year":"2006","unstructured":"Stewart A.D.; Jiang B.; Millasseau S.C.; Ritter J.M.; Chowienczyk P.J.; Acute reduction of blood pressure by nitroglycerin does not normalize large artery stiffness in essential hypertension. Hypertension 2006,48(3),404-410","journal-title":"Hypertension"},{"key":"ref=46","doi-asserted-by":"publisher","first-page":"2010","DOI":"10.1097\/HJH.0b013e32832e8dc8","volume":"27","author":"Eberth J.F.","year":"2009","unstructured":"Eberth J.F.; Gresham V.C.; Reddy A.K.; Popovic N.; Wilson E.; Humphrey J.D.; Importance of pulsatility in hypertensive carotid artery growth and remodeling. J Hypertens 2009,27(10),2010-2021","journal-title":"J Hypertens"},{"key":"ref=47","doi-asserted-by":"publisher","first-page":"1464","DOI":"10.1161\/hc3801.097806","volume":"104","author":"Kass D.A.","year":"2001","unstructured":"Kass D.A.; Shapiro E.P.; Kawaguchi M.; Capriotti A.R.; Scuteri A.; deGroof R.C.; Lakatta E.G.; Improved arterial compliance by a novel advanced glycation end-product crosslink breaker. Circulation 2001,104(13),1464-1470","journal-title":"Circulation"},{"key":"ref=48","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1161\/HYPERTENSIONAHA.111.187807","volume":"59","author":"Smith E.R.","year":"2012","unstructured":"Smith E.R.; Tomlinson L.A.; Ford M.L.; McMahon L.P.; Rajkumar C.; Holt S.G.; Elastin degradation is associated with progressive aortic stiffening and all-cause mortality in predialysis chronic kidney disease. Hypertension 2012,59(5),973-978","journal-title":"Hypertension"},{"key":"ref=49","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1161\/HYPERTENSIONAHA.112.191270","volume":"60","author":"Wang M.","year":"2012","unstructured":"Wang M.; Zhang J.; Telljohann R.; Jiang L.; Wu J.; Monticone R.E.; Kapoor K.; Talan M.; Lakatta E.G.; Chronic matrix metalloproteinase inhibition retards age-associated arterial proinflammation and increase in blood pressure. Hypertension 2012,60(2),459-466","journal-title":"Hypertension"},{"key":"ref=50","author":"Yasmin","year":"2005","unstructured":"Yasmin ; McEniery CM.; Wallace S.; Matrix metalloproteinase-9 (MMP-9), MMP-2, and serum elastase activity are associated with systolic hypertension and arterial stiffness. ArteriosclerThromb Vasc Biol 2005","journal-title":"ArteriosclerThromb Vasc Biol"},{"key":"ref=51","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1161\/01.ATV.0000227717.46157.32","volume":"26","author":"Yasmin","year":"2006","unstructured":"Yasmin ; McEniery CM.; O\u2019Shaughnessy K.M.; Variation in the human matrix metalloproteinase-9 gene is associated with arterial stiffness in healthy individuals. Arterioscler Thromb Vasc Biol 2006,26,1799-1805","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref=52","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/S0021-9150(02)00107-7","volume":"164","author":"P\u00f6ll\u00e4nen P.J.","year":"2002","unstructured":"P\u00f6ll\u00e4nen P.J.; Lehtim\u00e4ki T.; Ilveskoski E.; Mikkelsson J.; Kajander O.A.; Laippala P.; Perola M.; Goebeler S.; Penttil\u00e4 A.; Mattila K.M.; Syrj\u00e4koski K.; Koivula T.; Nikkari S.T.; Karhunen P.J.; Coronary artery calcification is related to functional polymorphism of matrix metalloproteinase 3: The Helsinki sudden death study. Atherosclerosis 2002,164(2),329-335","journal-title":"Atherosclerosis"},{"key":"ref=53","doi-asserted-by":"publisher","first-page":"1446","DOI":"10.1161\/hq0901.095545","volume":"21","author":"P\u00f6ll\u00e4nen P.J.","year":"2001","unstructured":"P\u00f6ll\u00e4nen P.J.; Karhunen P.J.; Mikkelsson J.; Laippala P.; Perola M.; Penttil\u00e4 A.; Mattila K.M.; Koivula T.; Lehtim\u00e4ki T.; Coronary artery complicated lesion area is related to functional polymorphism of matrix metalloproteinase 9 gene: An autopsy study. Arterioscler Thromb Vasc Biol 2001,21(9),1446-1450","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref=54","doi-asserted-by":"publisher","first-page":"3480","DOI":"10.1161\/01.CIR.0000148367.08413.E9","volume":"110","author":"Basalyga D.M.","year":"2004","unstructured":"Basalyga D.M.; Simionescu D.T.; Xiong W.; Baxter B.T.; Starcher B.C.; Vyavahare N.R.; Elastin degradation and calcification in an abdominal aorta injury model: Role of matrix metalloproteinases. Circulation 2004,110(22),3480-3487","journal-title":"Circulation"},{"key":"ref=55","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1002\/art.20002","volume":"50","author":"Booth A.D.","year":"2004","unstructured":"Booth A.D.; Wallace S.; McEniery C.M.; Yasmin ; Brown J.; Jayne D.R.; Wilkinson I.B.; Inflammation and arterial stiffness in systemic vasculitis: A model of vascular inflammation. Arthritis Rheum 2004,50(2),581-588","journal-title":"Arthritis Rheum"},{"key":"ref=56","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1161\/CIRCULATIONAHA.105.601641","volume":"114","author":"M\u00e4ki-Pet\u00e4j\u00e4 K.M.","year":"2006","unstructured":"M\u00e4ki-Pet\u00e4j\u00e4 K.M.; Hall F.C.; Booth A.D.; Wallace S.M.; Yasmin ; Bearcroft P.W.; Harish S.; Furlong A.; McEniery C.M.; Brown J.; Wilkinson I.B.; Rheumatoid arthritis is associated with increased aortic pulse-wave velocity, which is reduced by anti-tumor necrosis factor-alpha therapy. Circulation 2006,114(11),1185-1192","journal-title":"Circulation"},{"key":"ref=57","doi-asserted-by":"publisher","first-page":"2193","DOI":"10.1161\/CIRCULATIONAHA.105.535435","volume":"112","author":"Vlachopoulos C.","year":"2005","unstructured":"Vlachopoulos C.; Dima I.; Aznaouridis K.; Vasiliadou C.; Ioakeimidis N.; Aggeli C.; Toutouza M.; Stefanadis C.; Acute systemic inflammation increases arterial stiffness and decreases wave reflections in healthy individuals. Circulation 2005,112(14),2193-2200","journal-title":"Circulation"},{"key":"ref=58","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.artres.2012.03.002","volume":"6","author":"M\u00e4ki-Pet\u00e4j\u00e4 K.M.","year":"2012","unstructured":"M\u00e4ki-Pet\u00e4j\u00e4 K.M.; Wilkinson I.B.; Inflammation and large arteries: Potential mechanisms for inflammation-induced arterial stiffness. Artery Res 2012,6,59-64","journal-title":"Artery Res"},{"key":"ref=59","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1161\/HYPERTENSIONAHA.110.154005","volume":"56","author":"Cecelja M.","year":"2010","unstructured":"Cecelja M.; Chowienczyk P.; Arterial stiffening: Cause and prevention. Hypertension 2010,56(1),29-30","journal-title":"Hypertension"},{"key":"ref=60","doi-asserted-by":"publisher","first-page":"1754","DOI":"10.1161\/01.CIR.83.5.1754","volume":"83","author":"Farrar D.J.","year":"1991","unstructured":"Farrar D.J.; Bond M.G.; Riley W.A.; Sawyer J.K.; Anatomic correlates of aortic pulse wave velocity and carotid artery elasticity during atherosclerosis progression and regression in monkeys. Circulation 1991,83(5),1754-1763","journal-title":"Circulation"},{"key":"ref=61","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1161\/HYPERTENSIONAHA.108.126615","volume":"53","author":"McEniery C.M.","year":"2009","unstructured":"McEniery C.M.; McDonnell B.J.; So A.; Aitken S.; Bolton C.E.; Munnery M.; Hickson S.S.; Yasmin ; Maki-Petaja K.M.; Cockcroft J.R.; Dixon A.K.; Wilkinson I.B.; Aortic calcification is associated with aortic stiffness and isolated systolic hypertension in healthy individuals. Hypertension 2009,53(3),524-531","journal-title":"Hypertension"},{"key":"ref=62","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1161\/res.90.3.251","volume":"90","author":"Galis Z.S.","year":"2002","unstructured":"Galis Z.S.; Khatri J.J.; Matrix metalloproteinases in vascular remodeling and atherogenesis: The good, the bad, and the ugly. Circ Res 2002,90(3),251-262","journal-title":"Circ Res"},{"key":"ref=63","doi-asserted-by":"publisher","first-page":"1797","DOI":"10.1016\/S0140-6736(05)67726-4","volume":"366","author":"Ray J.G.","year":"2005","unstructured":"Ray J.G.; Vermeulen M.J.; Schull M.J.; Redelmeier D.A.; Cardiovascular health after maternal placental syndromes (CHAMPS): Population-based retrospective cohort study. Lancet 2005,366(9499),1797-1803","journal-title":"Lancet"},{"key":"ref=64","doi-asserted-by":"publisher","first-page":"S0002-9378(20) 30873-5","DOI":"10.1016\/j.ajog.2020.08.045","author":"Rolnik D.L.","year":"2020","unstructured":"Rolnik D.L.; Nicolaides K.H.; Poon L.C.; Prevention of preeclampsia with aspirin. Am J Obstet Gynecol 2020,S0002-9378(20) 30873-5","journal-title":"Am J Obstet Gynecol"},{"key":"ref=65","first-page":"e1","volume":"133","year":"2019","unstructured":"202: Gestational hypertension and preeclampsia. Obstet Gynecol ACOG Practice Bulletin No2019,133,e1-e25","journal-title":"Obstet Gynecol"},{"key":"ref=66","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1161\/01.HYP.0000054981.03589.E9","volume":"41","author":"Roberts J.M.","year":"2003","unstructured":"Roberts J.M.; Pearson G.; Cutler J.; Lindheimer M.; NHLBI working group on research on hypertension during pregnancy. Summary of the NHLBI working group on research on hypertension during pregnancy. Hypertension 2003,41(3),437-445","journal-title":"Hypertension"},{"key":"ref=67","doi-asserted-by":"publisher","first-page":"S0002-9378(20) 30868-1","DOI":"10.1016\/j.ajog.2020.08.040","author":"Smith D.D.","year":"2020","unstructured":"Smith D.D.; Costantine M.M.; The role of statins in the prevention of preeclampsia. Am J Obstet Gynecol 2020,S0002-9378(20) 30868-1","journal-title":"Am J Obstet Gynecol"},{"key":"ref=68","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1093\/bmb\/ldg005","volume":"67","author":"Duley L.","year":"2003","unstructured":"Duley L.; Pre-eclampsia and the hypertensive disorders of pregnancy. Br Med Bull 2003,67,161-176","journal-title":"Br Med Bull"},{"key":"ref=69","doi-asserted-by":"publisher","first-page":"544.e1","DOI":"10.1016\/j.ajog.2013.08.019","volume":"209","author":"Lisonkova S.","year":"2013","unstructured":"Lisonkova S.; Joseph K.S.; Incidence of preeclampsia: Risk factors and outcomes associated with early- versus late-onset disease. Am J Obstet Gynecol 2013,209(6),544.e1-544.e12","journal-title":"Am J Obstet Gynecol"},{"key":"ref=70","doi-asserted-by":"publisher","first-page":"1213","DOI":"10.1136\/bmj.323.7323.1213","volume":"323","author":"Irgens H.U.","year":"2001","unstructured":"Irgens H.U.; Reisaeter L.; Irgens L.M.; Lie R.T.; Long term mortality of mothers and fathers after pre-eclampsia: Population based cohort study. BMJ 2001,323(7323),1213-1217","journal-title":"BMJ"},{"key":"ref=71","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1002\/uog.5252","volume":"31","author":"Yu C.K.H.","year":"2008","unstructured":"Yu C.K.H.; Khouri O.; Onwudiwe N.; Spiliopoulos Y.; Nicolaides K.H.; Prediction of pre-eclampsia by uterine artery Doppler imaging: Relationship to gestational age at delivery and small-for-gestational age. Ultrasound Obstet Gynecol 2008,31(3),310-313","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref=72","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/S0140-6736(00)03577-7","volume":"357","author":"Roberts J.M.","year":"2001","unstructured":"Roberts J.M.; Cooper D.W.; Pathogenesis and genetics of pre-eclampsia. Lancet 2001,357(9249),53-56","journal-title":"Lancet"},{"key":"ref=73","doi-asserted-by":"publisher","first-page":"2393","DOI":"10.1210\/jc.2003-030241","volume":"88","author":"Seely E.W.","year":"2003","unstructured":"Seely E.W.; Solomon C.G.; Insulin resistance and its potential role in pregnancy-induced hypertension. J Clin Endocrinol Metab 2003,88(6),2393-2398","journal-title":"J Clin Endocrinol Metab"},{"key":"ref=74","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1182\/asheducation.V2012.1.203.3798262","volume":"2012","author":"Greer I.A.","year":"2012","unstructured":"Greer I.A.; Thrombosis in pregnancy: Updates in diagnosis and management. Hematology (Am Soc Hematol Educ Program) 2012,2012,203-207","journal-title":"Hematology (Am Soc Hematol Educ Program)"},{"key":"ref=75","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1161\/HYPERTENSIONAHA.107.107565","volume":"51","author":"Chappell L.C.","year":"2008","unstructured":"Chappell L.C.; Enye S.; Seed P.; Briley A.L.; Poston L.; Shennan A.H.; Adverse perinatal outcomes and risk factors for preeclampsia in women with chronic hypertension: A prospective study. Hypertension 2008,51(4),1002-1009","journal-title":"Hypertension"},{"key":"ref=76","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1016\/j.ahj.2008.06.042","volume":"156","author":"McDonald S.D.","year":"2008","unstructured":"McDonald S.D.; Malinowski A.; Zhou Q.; Yusuf S.; Devereaux P.J.; Cardiovascular sequelae of preeclampsia\/eclampsia: A systematic review and meta-analyses. Am Heart J 2008,156(5),918-930","journal-title":"Am Heart J"},{"key":"ref=77","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1161\/HYPERTENSIONAHA.110.150078","volume":"56","author":"Mongraw-Chaffin M.L.","year":"2010","unstructured":"Mongraw-Chaffin M.L.; Cirillo P.M.; Cohn B.A.; Preeclampsia and cardiovascular disease death: Prospective evidence from the child health and development studies cohort. Hypertension 2010,56(1),166-171","journal-title":"Hypertension"},{"key":"ref=78","doi-asserted-by":"publisher","first-page":"S0002-9378(20)31198-4","DOI":"10.1016\/j.ajog.2020.10.024","author":"Melchiorre K.","year":"2021","unstructured":"Melchiorre K.; Giorgione V.; Thilaganathan B.; The placenta and preeclampsia: Villain or victim? Am J Obstet Gynecol [Online ahead of print.].2021,S0002-9378(20)31198-4","journal-title":"Am J Obstet Gynecol"},{"key":"ref=79","doi-asserted-by":"publisher","first-page":"2111","DOI":"10.1016\/S0002-9440(10)64849-3","volume":"157","author":"Jauniaux E.","year":"2000","unstructured":"Jauniaux E.; Watson A.L.; Hempstock J.; Bao Y-P.; Skepper J.N.; Burton G.J.; Onset of maternal arterial blood flow and placental oxidative stress. A possible factor in human early pregnancy failure. Am J Pathol 2000,157(6),2111-2122","journal-title":"Am J Pathol"},{"key":"ref=80","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.placenta.2020.08.022","volume":"102","author":"de Alwis N.","year":"2020","unstructured":"de Alwis N.; Binder N.K.; Beard S.; Kaitu\u2019u-Lino T.J.; Tong S.; Brownfoot F.; Hannan N.J.; Novel approaches to combat preeclampsia: From new drugs to innovative delivery. Placenta 2020,102,10-16","journal-title":"Placenta"},{"key":"ref=81","doi-asserted-by":"publisher","first-page":"1877","DOI":"10.1016\/S0140-6736(02)08778-0","volume":"359","author":"Altman D.","year":"2002","unstructured":"Altman D.; Carroli G.; Duley L.; Farrell B.; Moodley J.; Neilson J.; Smith D.; Do women with pre-eclampsia, and their babies, benefit from magnesium sulphate? The Magpie Trial: A randomised placebo-controlled trial. Lancet 2002,359(9321),1877-1890","journal-title":"Lancet"},{"key":"ref=82","doi-asserted-by":"publisher","first-page":"e52","DOI":"10.1097\/AOG.0000000000001267","volume":"127","year":"2016","unstructured":"Committee Opinion No 652: Magnesium sulfate use in obstetrics. Obstet Gynecol 2016,127(1),e52-e53","journal-title":"Obstet Gynecol"},{"key":"ref=83","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1097\/AOG.0b013e3181a60495","volume":"113","author":"Doyle L.W.","year":"2009","unstructured":"Doyle L.W.; Crowther C.A.; Middleton P.; Marret S.; Antenatal magnesium sulfate and neurologic outcome in preterm infants: A systematic review. Obstet Gynecol 2009,113(6),1327-1333","journal-title":"Obstet Gynecol"},{"key":"ref=84","first-page":"CD004454","volume":"12","author":"McGoldrick E.","year":"2020","unstructured":"McGoldrick E.; Stewart F.; Parker R.; Dalziel S.R.; Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev 2020,12,CD004454","journal-title":"Cochrane Database Syst Rev"},{"key":"ref=85","doi-asserted-by":"publisher","first-page":"CD006614","DOI":"10.1002\/14651858.CD006614.pub3","volume":"8","author":"Sotiriadis A.","year":"2018","unstructured":"Sotiriadis A.; Makrydimas G.; Papatheodorou S.; Ioannidis J.P.; McGoldrick E.; Corticosteroids for preventing neonatal respiratory morbidity after elective caesarean section at term. Cochrane Database Syst Rev 2018,8,CD006614","journal-title":"Cochrane Database Syst Rev"},{"key":"ref=86","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.preghy.2014.02.001","volume":"4","author":"Tranquilli A.L.","year":"2014","unstructured":"Tranquilli A.L.; Dekker G.; Magee L.; Roberts J.; Sibai B.M.; Steyn W.; Zeeman G.G.; Brown M.A.; The classification, diagnosis and management of the hypertensive disorders of pregnancy: A revised statement from the ISSHP. Pregnancy Hypertens 2014,4(2),97-104","journal-title":"Pregnancy Hypertens"},{"key":"ref=87","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/j.ajog.2020.03.016","volume":"223","author":"Bellos I.","year":"2020","unstructured":"Bellos I.; Pergialiotis V.; Papapanagiotou A.; Loutradis D.; Daskalakis G.; Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: A network metaanalysis. Am J Obstet Gynecol 2020,223(4),525-537","journal-title":"Am J Obstet Gynecol"},{"key":"ref=88","doi-asserted-by":"publisher","first-page":"143","DOI":"10.2165\/11599040-000000000-00000","volume":"12","author":"Koumaras C.","year":"2012","unstructured":"Koumaras C.; Tzimou M.; Stavrinou E.; Griva T.; Gossios T.D.; Katsiki N.; Athyros V.G.; Mikhailidis D.P.; Karagiannis A.; Role of antihypertensive drugs in arterial \u2018de-stiffening\u2019 and central pulsatile hemodynamics. Am J Cardiovasc Drugs 2012,12(3),143-156","journal-title":"Am J Cardiovasc Drugs"},{"key":"ref=89","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.jash.2013.09.001","volume":"8","author":"Koumaras C.","year":"2014","unstructured":"Koumaras C.; Tziomalos K.; Stavrinou E.; Katsiki N.; Athyros V.G.; Mikhailidis D.P.; Karagiannis A.; Effects of renin-angiotensin-aldosterone system inhibitors and beta-blockers on markers of arterial stiffness. J Am Soc Hypertens 2014,8(2),74-82","journal-title":"J Am Soc Hypertens"},{"key":"ref=90","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1016\/j.thromres.2011.01.005","volume":"127","author":"Perneby C.","year":"2011","unstructured":"Perneby C.; Vahter M.; \u00c5kesson A.; Bremme K.; Hjemdahl P.; Thromboxane metabolite excretion during pregnancy--influence of preeclampsia and aspirin treatment. Thromb Res 2011,127(6),605-606","journal-title":"Thromb Res"},{"key":"ref=91","doi-asserted-by":"publisher","first-page":"CD004659","DOI":"10.1002\/14651858.CD004659.pub3","volume":"2019","author":"Duley L.","year":"2019","unstructured":"Duley L.; Meher S.; Hunter K.E.; Seidler A.L.; Askie L.M.; Antiplatelet agents for preventing pre-eclampsia and its complications. Cochrane Database Syst Rev 2019,2019(10),CD004659","journal-title":"Cochrane Database Syst Rev"},{"key":"ref=92","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/S0140-6736(19)32973-3","volume":"395","author":"Hoffman M.K.","year":"2020","unstructured":"Hoffman M.K.; Goudar S.S.; Kodkany B.S.; Metgud M.; Somannavar M.; Okitawutshu J.; Lokangaka A.; Tshefu A.; Bose C.L.; Mwapule A.; Mwenechanya M.; Chomba E.; Carlo W.A.; Chicuy J.; Figueroa L.; Garces A.; Krebs N.F.; Jessani S.; Zehra F.; Saleem S.; Goldenberg R.L.; Kurhe K.; Das P.; Patel A.; Hibberd P.L.; Achieng E.; Nyongesa P.; Esamai F.; Liechty E.A.; Goco N.; Hemingway-Foday J.; Moore J.; Nolen T.L.; McClure E.M.; Koso-Thomas M.; Miodovnik M.; Silver R.; Derman R.J.; Low-dose aspirin for the prevention of preterm delivery in nulliparous women with a singleton pregnancy (ASPIRIN): A randomised, double-blind, placebo-controlled trial. Lancet 2020,395(10220),285-293","journal-title":"Lancet"},{"key":"ref=93","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1159\/000341264","volume":"33","author":"Akolekar R.","year":"2013","unstructured":"Akolekar R.; Syngelaki A.; Poon L.; Wright D.; Nicolaides K.H.; Competing risks model in early screening for preeclampsia by biophysical and biochemical markers. Fetal Diagn Ther 2013,33(1),8-15","journal-title":"Fetal Diagn Ther"},{"key":"ref=94","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1056\/NEJMoa1704559","volume":"377","author":"Rolnik D.L.","year":"2017","unstructured":"Rolnik D.L.; Wright D.; Poon L.C.; O\u2019Gorman N.; Syngelaki A.; de Paco Matallana C.; Akolekar R.; Cicero S.; Janga D.; Singh M.; Molina F.S.; Persico N.; Jani J.C.; Plasencia W.; Papaioannou G.; Tenenbaum-Gavish K.; Meiri H.; Gizurarson S.; Maclagan K.; Nicolaides K.H.; Aspirin versus placebo in pregnancies at high risk for preterm preeclampsia. N Engl J Med 2017,377(7),613-622","journal-title":"N Engl J Med"},{"key":"ref=95","doi-asserted-by":"publisher","first-page":"685.e1","DOI":"10.1016\/j.ajog.2017.08.110","volume":"217","author":"Wright D.","year":"2017","unstructured":"Wright D.; Poon L.C.; Rolnik D.L.; Syngelaki A.; Delgado J.L.; Vojtassakova D.; de Alvarado M.; Kapeti E.; Rehal A.; Pazos A.; Carbone I.F.; Dutemeyer V.; Plasencia W.; Papantoniou N.; Nicolaides K.H.; Aspirin for Evidence-Based Preeclampsia Prevention trial: Influence of compliance on beneficial effect of aspirin in prevention of preterm preeclampsia. Am J Obstet Gynecol 2017,217(6),685.e1-685.e5","journal-title":"Am J Obstet Gynecol"},{"key":"ref=96","doi-asserted-by":"publisher","first-page":"585.e1","DOI":"10.1016\/j.ajog.2017.07.038","volume":"217","author":"Poon L.C.","year":"2017","unstructured":"Poon L.C.; Wright D.; Rolnik D.L.; Syngelaki A.; Delgado J.L.; Tsokaki T.; Leipold G.; Akolekar R.; Shearing S.; De Stefani L.; Jani J.C.; Plasencia W.; Evangelinakis N.; Gonzalez-Vanegas O.; Persico N.; Nicolaides K.H.; Aspirin for evidence-based preeclampsia prevention trial: Effect of aspirin in prevention of preterm preeclampsia in subgroups of women according to their characteristics and medical and obstetrical history. Am J Obstet Gynecol 2017,217(5),585.e1-585.e5","journal-title":"Am J Obstet Gynecol"},{"key":"ref=97","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1161\/HYPERTENSIONAHA.114.03575","volume":"64","author":"Brandes R.P.","year":"2014","unstructured":"Brandes R.P.; Endothelial dysfunction and hypertension. Hypertension 2014,64(5),924-928","journal-title":"Hypertension"},{"key":"ref=98","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1161\/HYPERTENSIONAHA.110.163576","volume":"57","author":"Harrison D.G.","year":"2011","unstructured":"Harrison D.G.; Guzik T.J.; Lob H.E.; Madhur M.S.; Marvar P.J.; Thabet S.R.; Vinh A.; Weyand C.M.; Inflammation, immunity, and hypertension. Hypertension 2011,57(2),132-140","journal-title":"Hypertension"},{"key":"ref=99","doi-asserted-by":"publisher","first-page":"S32","DOI":"10.1016\/j.placenta.2008.11.009","volume":"30","author":"Roberts JM","year":"2009","unstructured":"Roberts JM; Hubel CA; The two stage model of preeclampsia: Variations on the theme. Placenta 2009,30(Suppl A),S32-S37","journal-title":"Placenta"},{"key":"ref=100","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/S0002-9378(98)70254-6","volume":"179","author":"Sacks G.P.","year":"1998","unstructured":"Sacks G.P.; Studena K.; Sargent K.; Redman C.W.; Normal pregnancy and preeclampsia both produce inflammatory changes in peripheral blood leukocytes akin to those of sepsis. Am J Obstet Gynecol 1998,179(1),80-86","journal-title":"Am J Obstet Gynecol"},{"key":"ref=101","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1111\/j.1471-0528.1998.tb09974.x","volume":"105","author":"Morris J.M.","year":"1998","unstructured":"Morris J.M.; Gopaul N.K.; Endresen M.J.; Knight M.; Linton E.A.; Dhir S.; Angg\u00e5rd E.E.; Redman C.W.; Circulating markers of oxidative stress are raised in normal pregnancy and pre-eclampsia. Br J Obstet Gynaecol 1998,105(11),1195-1199","journal-title":"Br J Obstet Gynaecol"},{"key":"ref=102","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1002\/uog.17517","volume":"50","author":"Panaitescu A.M.","year":"2017","unstructured":"Panaitescu A.M.; Akolekar R.; Kametas N.; Syngelaki A.; Nicolaides K.H.; Impaired placentation in women with chronic hypertension who develop pre-eclampsia. Ultrasound Obstet Gynecol 2017,50(4),496-500","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref=103","doi-asserted-by":"publisher","first-page":"612.e1","DOI":"10.1016\/j.ajog.2018.02.014","volume":"218","author":"Wright D.","year":"2018","unstructured":"Wright D.; Rolnik D.L.; Syngelaki A.; de Paco Matallana C.; Machuca M.; de Alvarado M.; Mastrodima S.; Tan M.Y.; Shearing S.; Persico N.; Jani J.C.; Plasencia W.; Papaioannou G.; Molina F.S.; Poon L.C.; Nicolaides K.H.; Aspirin for Evidence-Based Preeclampsia Prevention trial: Effect of aspirin on length of stay in the neonatal intensive care unit. Am J Obstet Gynecol 2018,218(6),612.e1-612.e6","journal-title":"Am J Obstet Gynecol"},{"key":"ref=104","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1002\/uog.19077","volume":"52","author":"Tan M.Y.","year":"2018","unstructured":"Tan M.Y.; Poon L.C.; Rolnik D.L.; Syngelaki A.; de Paco Matallana C.; Akolekar R.; Cicero S.; Janga D.; Singh M.; Molina F.S.; Persico N.; Jani J.C.; Plasencia W.; Greco E.; Papaioannou G.; Wright D.; Nicolaides K.H.; Prediction and prevention of small-for-gestational-age neonates: Evidence from SPREE and ASPRE. Ultrasound Obstet Gynecol 2018,52(1),52-59","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref=105","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1159\/000509662","volume":"47","author":"Llurba E.","year":"2020","unstructured":"Llurba E.; Bella M.; Burgos J.; Mazarico E.; G\u00f3mez-Roig M.D.; De Diego R.; Mart\u00ednez-Astorquiza T.; Alijotas-Reig J.; S\u00e1nchez-Dur\u00e1n M.\u00c1.; S\u00e1nchez O.; Carreras E.; Cabero L.; Early Prophylactic enoxaparin for the prevention of preeclampsia and intrauterine growth restriction: A randomized trial. Fetal Diagn Ther 2020,47(11),824-833","journal-title":"Fetal Diagn Ther"},{"key":"ref=106","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1161\/HYPERTENSIONAHA.116.08408","volume":"69","author":"Onda K.","year":"2017","unstructured":"Onda K.; Tong S.; Beard S.; Binder N.; Muto M.; Senadheera S.N.; Parry L.; Dilworth M.; Renshall L.; Brownfoot F.; Hastie R.; Tuohey L.; Palmer K.; Hirano T.; Ikawa M.; Kaitu\u2019u-Lino T.; Hannan N.J.; Proton pump inhibitors decrease soluble fms-like tyrosine kinase-1 and soluble endoglin secretion, decrease hypertension, and rescue endothelial dysfunction. Hypertension 2017,69(3),457-468","journal-title":"Hypertension"},{"key":"ref=107","doi-asserted-by":"publisher","first-page":"388.e1","DOI":"10.1016\/j.ajog.2018.07.019","volume":"219","author":"Cluver C.A.","year":"2018","unstructured":"Cluver C.A.; Hannan N.J.; van Papendorp E.; Hiscock R.; Beard S.; Mol B.W.; Theron G.B.; Hall D.R.; Decloedt E.H.; Stander M.; Adams K.T.; Rensburg M.; Schubert P.; Walker S.P.; Tong S.; Esomeprazole to treat women with preterm preeclampsia: A randomized placebo controlled trial. Am J Obstet Gynecol 2018,219(4),388.e1-388.e17","journal-title":"Am J Obstet Gynecol"},{"key":"ref=108","doi-asserted-by":"publisher","first-page":"e0188845","DOI":"10.1371\/journal.pone.0188845","volume":"13","author":"Kaitu\u2019u-Lino T.J.","year":"2018","unstructured":"Kaitu\u2019u-Lino T.J.; Brownfoot F.C.; Beard S.; Cannon P.; Hastie R.; Nguyen T.V.; Binder N.K.; Tong S.; Hannan N.J.; Combining metformin and esomeprazole is additive in reducing sFlt-1 secretion and decreasing endothelial dysfunction - implications for treating preeclampsia. PLoS One 2018,13(2),e0188845","journal-title":"PLoS One"},{"key":"ref=109","doi-asserted-by":"publisher","first-page":"356.e1","DOI":"10.1016\/j.ajog.2015.12.019","volume":"214","author":"Brownfoot F.C.","year":"2016","unstructured":"Brownfoot F.C.; Hastie R.; Hannan N.J.; Cannon P.; Tuohey L.; Parry L.J.; Senadheera S.; Illanes S.E.; Kaitu\u2019u-Lino T.J.; Tong S.; Metformin as a prevention and treatment for preeclampsia: Effects on soluble fms-like tyrosine kinase 1 and soluble endoglin secretion and endothelial dysfunction. Am J Obstet Gynecol 2016,214(3),356.e1-356.e15","journal-title":"Am J Obstet Gynecol"},{"key":"ref=110","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1161\/HYPERTENSIONAHA.115.05445","volume":"66","author":"Brownfoot F.C.","year":"2015","unstructured":"Brownfoot F.C.; Tong S.; Hannan N.J.; Binder N.K.; Walker S.P.; Cannon P.; Hastie R.; Onda K.; Kaitu\u2019u-Lino T.J.; Effects of pravastatin on human placenta, endothelium, and women with severe preeclampsia. Hypertension 2015,66(3),687-697","journal-title":"Hypertension"},{"key":"ref=111","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1186\/s12884-016-0902-3","volume":"16","author":"Brownfoot F.C.","year":"2016","unstructured":"Brownfoot F.C.; Tong S.; Hannan N.J.; Hastie R.; Cannon P.; Kaitu\u2019u-Lino T.J.; Effects of simvastatin, rosuvastatin and pravastatin on soluble fms-like tyrosine kinase 1 (sFlt-1) and soluble endoglin (sENG) secretion from human umbilical vein endothelial cells, primary trophoblast cells and placenta. BMC Pregnancy Childbirth 2016,16,117","journal-title":"BMC Pregnancy Childbirth"},{"key":"ref=112","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1016\/j.ebiom.2019.02.013","volume":"41","author":"Brownfoot F.C.","year":"2019","unstructured":"Brownfoot F.C.; Hannan N.J.; Cannon P.; Nguyen V.; Hastie R.; Parry L.J.; Senadheera S.; Tuohey L.; Tong S.; Kaitu\u2019u-Lino T.J.; Sulfasalazine reduces placental secretion of antiangiogenic factors, up-regulates the secretion of placental growth factor and rescues endothelial dysfunction. EBioMedicine 2019,41,636-648","journal-title":"EBioMedicine"},{"key":"ref=113","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1161\/HYPERTENSIONAHA.114.04781","volume":"65","author":"Onda K.","year":"2015","unstructured":"Onda K.; Tong S.; Nakahara A.; Kondo M.; Monchusho H.; Hirano T.; Kaitu\u2019u-Lino T.; Beard S.; Binder N.; Tuohey L.; Brownfoot F.; Hannan N.J.; Sofalcone upregulates the nuclear factor (erythroid-derived 2)-like 2\/heme oxygenase-1 pathway, reduces soluble fms-like tyrosine kinase-1, and quenches endothelial dysfunction: Potential therapeutic for preeclampsia. Hypertension 2015,65(4),855-862","journal-title":"Hypertension"},{"key":"ref=114","doi-asserted-by":"publisher","first-page":"1819","DOI":"10.1038\/s41598-017-01993-w","volume":"7","author":"Hannan N.J.","year":"2017","unstructured":"Hannan N.J.; Brownfoot F.C.; Cannon P.; Deo M.; Beard S.; Nguyen T.V.; Palmer K.R.; Tong S.; Kaitu\u2019u-Lino T.J.; Resveratrol inhibits release of soluble fms-like tyrosine kinase (sFlt-1) and soluble endoglin and improves vascular dysfunction - implications as a preeclampsia treatment. Sci Rep 2017,7(1),1819","journal-title":"Sci Rep"},{"key":"ref=115","doi-asserted-by":"publisher","first-page":"e0187082","DOI":"10.1371\/journal.pone.0187082","volume":"13","author":"Hannan N.J.","year":"2018","unstructured":"Hannan N.J.; Binder N.K.; Beard S.; Nguyen T-V.; Kaitu\u2019u-Lino T.J.; Tong S.; Melatonin enhances antioxidant molecules in the placenta, reduces secretion of soluble fms-like tyrosine kinase 1 (sFLT) from primary trophoblast but does not rescue endothelial dysfunction: An evaluation of its potential to treat preeclampsia. PLoS One 2018,13(4),e0187082","journal-title":"PLoS One"},{"key":"ref=116","doi-asserted-by":"publisher","first-page":"296.e1","DOI":"10.1016\/j.ajog.2017.01.014","volume":"216","author":"Groom K.M.","year":"2017","unstructured":"Groom K.M.; McCowan L.M.; Mackay L.K.; Lee A.C.; Said J.M.; Kane S.C.; Walker S.P.; van Mens T.E.; Hannan N.J.; Tong S.; Chamley L.W.; Stone P.R.; McLintock C.; Enoxaparin for the prevention of preeclampsia and\u00a0intrauterine growth restriction in women with\u00a0a\u00a0history:\u00a0A\u00a0randomized trial. Am J Obstet Gynecol 2017,216(3),296.e1-296.e14","journal-title":"Am J Obstet Gynecol"},{"key":"ref=117","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1002\/uog.19084","volume":"52","author":"Kalafat E.","year":"2018","unstructured":"Kalafat E.; Sukur Y.E.; Abdi A.; Thilaganathan B.; Khalil A.; Metformin for prevention of hypertensive disorders of pregnancy in women with gestational diabetes or obesity: Systematic review and meta-analysis of randomized trials. Ultrasound Obstet Gynecol 2018,52(6),706-714","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref=118","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1111\/dme.13523","volume":"35","author":"Alqudah A.","year":"2018","unstructured":"Alqudah A.; McKinley M.C.; McNally R.; Graham U.; Watson C.J.; Lyons T.J.; McClements L.; Risk of pre-eclampsia in women taking metformin: A systematic review and meta-analysis. Diabet Med 2018,35(2),160-172","journal-title":"Diabet Med"},{"key":"ref=119","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1056\/NEJMoa1509819","volume":"374","author":"Syngelaki A.","year":"2016","unstructured":"Syngelaki A.; Nicolaides K.H.; Balani J.; Hyer S.; Akolekar R.; Kotecha R.; Pastides A.; Shehata H.; Metformin versus placebo in obese pregnant women without diabetes mellitus. N Engl J Med 2016,374(5),434-443","journal-title":"N Engl J Med"},{"key":"ref=120","doi-asserted-by":"publisher","first-page":"720.e1","DOI":"10.1016\/j.ajog.2015.12.038","volume":"214","author":"Costantine M.M.","year":"2016","unstructured":"Costantine M.M.; Cleary K.; Hebert M.F.; Ahmed M.S.; Brown L.M.; Ren Z.; Easterling T.R.; Haas D.M.; Haneline L.S.; Caritis S.N.; Venkataramanan R.; West H.; D\u2019Alton M.; Hankins G.; \nSafety and pharmacokinetics of pravastatin used for the prevention of preeclampsia in high-risk pregnant women: A pilot randomized controlled trial. Am J Obstet Gynecol 2016,214(6),720.e1-720.e17","journal-title":"Am J Obstet Gynecol"},{"key":"ref=121","doi-asserted-by":"publisher","first-page":"2933","DOI":"10.1172\/JCI86957","volume":"126","author":"Lefkou E.","year":"2016","unstructured":"Lefkou E.; Mamopoulos A.; Dagklis T.; Vosnakis C.; Rousso D.; Girardi G.; Pravastatin improves pregnancy outcomes in obstetric antiphospholipid syndrome refractory to antithrombotic therapy. J Clin Invest 2016,126(8),2933-2940","journal-title":"J Clin Invest"},{"key":"ref=122","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1111\/1471-0528.16013","volume":"127","author":"Ahmed A.","year":"2020","unstructured":"Ahmed A.; Williams D.J.; Cheed V.; Middleton L.J.; Ahmad S.; Wang K.; Vince A.T.; Hewett P.; Spencer K.; Khan K.S.; Daniels J.P.; Pravastatin for early-onset pre-eclampsia: A randomised, blinded, placebo-controlled trial. BJOG 2020,127(4),478-488","journal-title":"BJOG"},{"key":"ref=123","doi-asserted-by":"publisher","first-page":"1472","DOI":"10.1055\/s-0040-1713651","volume":"38","author":"Mendoza M.","year":"2021","unstructured":"Mendoza M.; Ferrer-Oliveras R.; Bonacina E.; Garcia-Manau P.; Rodo C.; Carreras E.; Alijotas-Reig J.; Evaluating the effect of pravastatin in early-onset fetal growth restriction: A nonrandomized and historically controlled pilot study. Am J Perinatol 2021,38(14),1472-9","journal-title":"Am J Perinatol"},{"key":"ref=124","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1097\/AOG.0000000000001518","volume":"128","author":"Trapani A.","year":"2016","unstructured":"Trapani A.; Gon\u00e7alves L.F.; Trapani T.F.; Vieira S.; Pires M.; Pires M.M.S.; Perinatal and hemodynamic evaluation of sildenafil citrate for preeclampsia treatment: A randomized controlled trial. Obstet Gynecol 2016,128(2),253-259","journal-title":"Obstet Gynecol"},{"key":"ref=125","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1097\/AOG.0000000000001928","volume":"129","author":"Maher M.A.","year":"2017","unstructured":"Maher M.A.; Sayyed T.M.; Elkhouly N.; Sildenafil citrate therapy for oligohydramnios: A randomized controlled trial. Obstet Gynecol 2017,129(4),615-620","journal-title":"Obstet Gynecol"},{"key":"ref=126","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1161\/HYPERTENSIONAHA.117.09690","volume":"70","author":"Paauw N.D.","year":"2017","unstructured":"Paauw N.D.; Terstappen F.; Ganzevoort W.; Joles J.A.; Gremmels H.; Lely A.T.; Sildenafil during pregnancy: A preclinical meta-analysis on fetal growth and maternal blood pressure. Hypertension 2017,70(5),998-1006","journal-title":"Hypertension"},{"key":"ref=127","doi-asserted-by":"publisher","first-page":"k3247","DOI":"10.1136\/bmj.k3247","volume":"362","author":"Hawkes N.","year":"2018","unstructured":"Hawkes N.; Trial of Viagra for fetal growth restriction is halted after baby deaths. BMJ 2018,362,k3247","journal-title":"BMJ"},{"key":"ref=128","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/S2352-4642(17)30173-6","volume":"2","author":"Sharp A.","year":"2018","unstructured":"Sharp A.; Cornforth C.; Jackson R.; Harrold J.; Turner M.A.; Kenny L.C.; Baker P.N.; Johnstone E.D.; Khalil A.; von Dadelszen P.; Papageorghiou A.T.; Alfirevic Z.; Maternal sildenafil for severe fetal growth restriction (STRIDER): A multicentre, randomised, placebo-controlled, double-blind trial. Lancet Child Adolesc Health 2018,2(2),93-102","journal-title":"Lancet Child Adolesc Health"},{"key":"ref=129","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/s13063-018-3136-z","volume":"20","author":"Pels A.","year":"2019","unstructured":"Pels A.; Jakobsen J.C.; Ganzevoort W.; Naaktgeboren C.A.; Onland W.; van Wassenaer-Leemhuis A.G.; Gluud C.; Detailed statistical analysis plan for the Dutch STRIDER (Sildenafil The Rapy In Dismal prognosis Early-onset fetal growth Restriction) randomised clinical trial on sildenafil versus placebo for pregnant women with severe early onset fetal growth restriction. Trials 2019,20(1),42","journal-title":"Trials"},{"key":"ref=130","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1002\/uog.19186","volume":"52","author":"Groom K.M.","year":"2018","unstructured":"Groom K.M.; Ganzevoort W.; Alfirevic Z.; Lim K.; Papageorghiou A.T.; Clinicians should stop prescribing sildenafil for fetal growth restriction (FGR): Comment from the STRIDER Consortium. Ultrasound Obstet Gynecol 2018,52(3),295-296","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref=131","doi-asserted-by":"publisher","first-page":"e18703","DOI":"10.1371\/journal.pone.0018703","volume":"6","author":"Savvidou M.D.","year":"2011","unstructured":"Savvidou M.D.; Kaihura C.; Anderson J.M.; Nicolaides K.H.; Maternal arterial stiffness in women who subsequently develop pre-eclampsia. PLoS One 2011,6(5),e18703","journal-title":"PLoS One"},{"key":"ref=132","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1111\/aogs.12145","volume":"92","author":"Franz M.B.","year":"2013","unstructured":"Franz M.B.; Burgmann M.; Neubauer A.; Zeisler H.; Sanani R.; Gottsauner-Wolf M.; Schiessl B.; Andreas M.; Augmentation index and pulse wave velocity in normotensive and pre-eclamptic pregnancies. Acta Obstet Gynecol Scand 2013,92(8),960-966","journal-title":"Acta Obstet Gynecol Scand"},{"key":"ref=133","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1002\/uog.7559","volume":"35","author":"Khalil A.","year":"2010","unstructured":"Khalil A.; Cowans N.J.; Spencer K.; Goichman S.; Meiri H.; Harrington K.; First-trimester markers for the prediction of pre-eclampsia in women with a-priori high risk. Ultrasound Obstet Gynecol 2010,35(6),671-679","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref=134","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1002\/uog.11183","volume":"40","author":"Khalil A.","year":"2012","unstructured":"Khalil A.; Akolekar R.; Syngelaki A.; Elkhouli M.; Nicolaides K.H.; Maternal hemodynamics at 11-13 weeks\u2019 gestation and risk of pre-eclampsia. Ultrasound Obstet Gynecol 2012,40(1),28-34","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref=135","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1097\/GCO.0000000000000419","volume":"29","author":"Kalafat E.","year":"2017","unstructured":"Kalafat E.; Thilaganathan B.; Cardiovascular origins of preeclampsia. Curr Opin Obstet Gynecol 2017,29(6),383-389","journal-title":"Curr Opin Obstet Gynecol"},{"key":"ref=136","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1038\/jhh.2013.64","volume":"28","author":"Carty D.M.","year":"2014","unstructured":"Carty D.M.; Neisius U.; Rooney L.K.; Dominiczak A.F.; Delles C.; Pulse wave analysis for the prediction of preeclampsia. J Hum Hypertens 2014,28(2),98-104","journal-title":"J Hum Hypertens"},{"key":"ref=137","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1097\/00006250-200104000-00007","volume":"97","author":"Thadhani R.","year":"2001","unstructured":"Thadhani R.; Ecker J.L.; Kettyle E.; Sandler L.; Frigoletto F.D.; Pulse pressure and risk of preeclampsia: A prospective study. Obstet Gynecol 2001,97(4),515-520","journal-title":"Obstet Gynecol"},{"key":"ref=138","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.preghy.2019.09.001","volume":"18","author":"Cooper K.M.","year":"2019","unstructured":"Cooper K.M.; Barrett T.; McBride C.A.; Badger G.J.; Steiner J.; LeWinter M.M.; Bernstein I.M.; Subclinical cardiac stiffness is associated with arterial stiffness in healthy young nulligravid women: Potential links to preeclampsia. Pregnancy Hypertens 2019,18,49-54","journal-title":"Pregnancy Hypertens"},{"key":"ref=139","doi-asserted-by":"publisher","first-page":"1447","DOI":"10.1161\/HYPERTENSIONAHA.116.07907","volume":"68","author":"Grand\u2019Maison S.","year":"2016","unstructured":"Grand\u2019Maison S.; Pilote L.; Okano M.; Landry T.; Dayan N.; Markers of vascular dysfunction after hypertensive disorders of pregnancy: A systematic review and meta-analysis. Hypertension 2016,68(6),1447-1458","journal-title":"Hypertension"},{"key":"ref=140","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1136\/bmj.39335.385301.BE","volume":"335","author":"Bellamy L.","year":"2007","unstructured":"Bellamy L.; Casas J-P.; Hingorani A.D.; Williams D.J.; Pre-eclampsia and risk of cardiovascular disease and cancer in later life: Systematic review and meta-analysis. BMJ 2007,335(7627),974","journal-title":"BMJ"},{"key":"ref=141","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1111\/j.1469-7793.2000.t01-1-00263.x","volume":"525","author":"Wilkinson I.B.","year":"2000","unstructured":"Wilkinson I.B.; MacCallum H.; Flint L.; Cockcroft J.R.; Newby D.E.; Webb D.J.; The influence of heart rate on augmentation index and central arterial pressure in humans. J Physiol 2000,525(Pt 1),263-270","journal-title":"J Physiol"},{"key":"ref=142","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1097\/HJH.0b013e3282f314f7","volume":"26","author":"Baulmann J.","year":"2008","unstructured":"Baulmann J.; Schillings U.; Rickert S.; Uen S.; D\u00fcsing R.; Illyes M.; Cziraki A.; Nickering G.; Mengden T.; A new oscillometric method for assessment of arterial stiffness: Comparison with tonometric and piezo-electronic methods. J Hypertens 2008,26(3),523-528","journal-title":"J Hypertens"},{"key":"ref=143","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1002\/ejhf.1436","volume":"21","author":"Ikonomidis I.","year":"2019","unstructured":"Ikonomidis I.; Aboyans V.; Blacher J.; Brodmann M.; Brutsaert D.L.; Chirinos J.A.; De Carlo M.; Delgado V.; Lancellotti P.; Lekakis J.; Mohty D.; Nihoyannopoulos P.; Parissis J.; Rizzoni D.; Ruschitzka F.; Seferovic P.; Stabile E.; Tousoulis D.; Vinereanu D.; Vlachopoulos C.; Vlastos D.; Xaplanteris P.; Zimlichman R.; Metra M.; The role of ventricular-arterial coupling in cardiac disease and heart failure: Assessment, clinical implications and therapeutic interventions. A consensus document of the European society of cardiology working group on aorta","journal-title":"Eur J Heart Fail"},{"key":"ref=144","doi-asserted-by":"publisher","first-page":"SI14","DOI":"10.1016\/S0140-6736(97)90023-4","volume":"350","author":"Lehmann E.D.","year":"1997","unstructured":"Lehmann E.D.; Riley W.A.; Clarkson P.; Gosling R.G.; Non-invasive assessment of cardiovascular disease in diabetes mellitus. Lancet 1997,350(Suppl. 1),SI14-SI19","journal-title":"Lancet"},{"key":"ref=145","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1161\/01.HYP.37.5.1236","volume":"37","author":"Laurent S.","year":"2001","unstructured":"Laurent S.; Boutouyrie P.; Asmar R.; Gautier I.; Laloux B.; Guize L.; Ducimetiere P.; Benetos A.; Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension 2001,37(5),1236-1241","journal-title":"Hypertension"},{"key":"ref=146","doi-asserted-by":"publisher","first-page":"2588","DOI":"10.1093\/eurheartj\/ehl254","volume":"27","author":"Laurent S.","year":"2006","unstructured":"Laurent S.; Cockcroft J.; Van Bortel L.; Boutouyrie P.; Giannattasio C.; Hayoz D.; Pannier B.; Vlachopoulos C.; Wilkinson I.; Struijker-Boudier H.; Expert consensus document on arterial stiffness: Methodological issues and clinical applications. Eur Heart J 2006,27(21),2588-2605","journal-title":"Eur Heart J"},{"key":"ref=147","first-page":"1462","volume":"28","author":"Mancia G.","year":"2007","unstructured":"Mancia G.; De Backer G.; Dominiczak A.; Cifkova R.; Fagard R.; Germano G.; Grassi G.; Heagerty A.M.; Kjeldsen S.E.; Laurent S.; Narkiewicz K.; Ruilope L.; Rynkiewicz A.; Schmieder R.E.; Struijker Boudier H.A.; Zanchetti A.; Vahanian A.; Camm J.; De Caterina R.; Dean V.; Dickstein K.; Filippatos G.; Funck-Brentano C.; Hellemans I.; Kristensen S.D.; McGregor K.; Sechtem U.; Silber S.; Tendera M.; Widimsky P.; Zamorano J.L.; Kjeldsen S.E.; Erdine S.; Narkiewicz K.; Kiowski W.; Agabiti-Rosei E.; Ambrosioni E.; Cifkova R.; Dominiczak A.; Fagard R.; Heagerty A.M.; Laurent S.; Lindholm L.H.; Mancia G.; Manolis A.; Nilsson P.M.; Redon J.; Schmieder R.E.; Struijker-Boudier H.A.; Viigimaa M.; Filippatos G.; Adamopoulos S.; Agabiti-Rosei E.; Ambrosioni E.; Bertomeu V.; Clement D.; Erdine S.; Farsang C.; Gaita D.; Kiowski W.; Lip G.; Mallion J.M.; Manolis A.J.; Nilsson P.M.; O\u2019Brien E.; Ponikowski P.; Redon J.; Ruschitzka F.; Tamargo J.; van Zwieten P.; Viigimaa M.; Waeber B.; Williams B.; Zamorano J.L.; 2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 2007,28(12),1462-1536","journal-title":"Eur Heart J"},{"key":"ref=148","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1161\/01.HYP.33.5.1111","volume":"33","author":"Blacher J.","year":"1999","unstructured":"Blacher J.; Asmar R.; Djane S.; London G.M.; Safar M.E.; Aortic pulse wave velocity as a marker of cardiovascular risk in hypertensive patients. Hypertension 1999,33(5),1111-1117","journal-title":"Hypertension"},{"key":"ref=149","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1161\/hy0102.099031","volume":"39","author":"Boutouyrie P.","year":"2002","unstructured":"Boutouyrie P.; Tropeano A.I.; Asmar R.; Gautier I.; Benetos A.; Lacolley P.; Laurent S.; Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: A longitudinal study. Hypertension 2002,39(1),10-15","journal-title":"Hypertension"},{"key":"ref=150","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1161\/CIRCULATIONAHA.105.579342","volume":"113","author":"Willum-Hansen T.","year":"2006","unstructured":"Willum-Hansen T.; Staessen J.A.; Torp-Pedersen C.; Rasmussen S.; Thijs L.; Ibsen H.; Jeppesen J.; Prognostic value of aortic pulse wave velocity as index of arterial stiffness in the general population. Circulation 2006,113(5),664-670","journal-title":"Circulation"},{"key":"ref=151","doi-asserted-by":"publisher","first-page":"2434","DOI":"10.1161\/01.CIR.99.18.2434","volume":"99","author":"Blacher J.","year":"1999","unstructured":"Blacher J.; Guerin A.P.; Pannier B.; Marchais S.J.; Safar M.E.; London G.M.; Impact of aortic stiffness on survival in end-stage renal disease. Circulation 1999,99(18),2434-2439","journal-title":"Circulation"},{"key":"ref=152","doi-asserted-by":"publisher","first-page":"2046","DOI":"10.1161\/hq1201.100226","volume":"21","author":"Meaume S.","year":"2001","unstructured":"Meaume S.; Benetos A.; Henry O.F.; Rudnichi A.; Safar M.E.; Aortic pulse wave velocity predicts cardiovascular mortality in subjects >70 years of age. Arterioscler Thromb Vasc Biol 2001,21(12),2046-2050","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref=153","doi-asserted-by":"publisher","first-page":"2117","DOI":"10.1681\/ASN.V12102117","volume":"12","author":"Shoji T.","year":"2001","unstructured":"Shoji T.; Emoto M.; Shinohara K.; Kakiya R.; Tsujimoto Y.; Kishimoto H.; Ishimura E.; Tabata T.; Nishizawa Y.; Diabetes mellitus, aortic stiffness, and cardiovascular mortality in end-stage renal disease. J Am Soc Nephrol 2001,12(10),2117-2124","journal-title":"J Am Soc Nephrol"},{"key":"ref=154","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1093\/eurheartj\/ehq024","volume":"13","author":"Vlachopoulos C","year":"2010","unstructured":"Vlachopoulos C; Aznaouridis K; O\u2019Rourke MF; Safar ME; Baou K; Stefanadis C; Prediction of cardiovascular events and all-cause mortality with central haemodynamics: A systematic review and meta-analysis. Eur Heart J 2010,13(1),865-871","journal-title":"Eur Heart J"},{"key":"ref=155","first-page":"H1363","volume":"269","author":"Karamanoglu M.","year":"1995","unstructured":"Karamanoglu M.; Gallagher D.E.; Avolio A.P.; O\u2019Rourke M.F.; Pressure wave propagation in a multibranched model of the human upper limb. Am J Physiol 1995,269(4 Pt 2),H1363-H1369","journal-title":"Am J Physiol"},{"key":"ref=156","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1016\/S0895-7061(02)02962-X","volume":"15","author":"Pannier B.M.","year":"2002","unstructured":"Pannier B.M.; Avolio A.P.; Hoeks A.; Mancia G.; Takazawa K.; Methods and devices for measuring arterial compliance in humans. Am J Hypertens 2002,15(8),743-753","journal-title":"Am J Hypertens"},{"key":"ref=157","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1161\/01.HYP.0000159190.71253.c3","volume":"45","author":"Pannier B.","year":"2005","unstructured":"Pannier B.; Gu\u00e9rin A.P.; Marchais S.J.; Safar M.E.; London G.M.; Stiffness of capacitive and conduit arteries: Prognostic significance for end-stage renal disease patients. Hypertension 2005,45(4),592-596","journal-title":"Hypertension"},{"key":"ref=158","doi-asserted-by":"publisher","first-page":"531","DOI":"10.3109\/10641963.2014.913608","volume":"36","author":"Oylumlu M.","year":"2014","unstructured":"Oylumlu M.; Oylumlu M.; Yuksel M.; Yildiz A.; Bilik M.Z.; Akil M.A.; Ozler A.; Acet H.; Ertas F.; Alan S.; A simple method for the assessment of arterial stiffness in pre-eclamptic patients. Clin Exp Hypertens 2014,36(8),531-537","journal-title":"Clin Exp Hypertens"}],"container-title":["Current Vascular Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.eurekaselect.com\/article\/download?doi=10.2174\/1570161119666211006114258","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/197035\/article","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/article\/download?doi=10.2174\/1570161119666211006114258","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,12]],"date-time":"2023-08-12T18:30:02Z","timestamp":1691865002000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurekaselect.com\/197035\/article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":158,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["LiveAll1"],"URL":"https:\/\/doi.org\/10.2174\/1570161119666211006114258","relation":{},"ISSN":["1570-1611"],"issn-type":[{"value":"1570-1611","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2021-05-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-08","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}