{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:40:45Z","timestamp":1753890045580,"version":"3.41.2"},"reference-count":86,"publisher":"Bentham Science Publishers Ltd.","issue":"2","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["CDDT"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:sec>\n<jats:title>Background:<\/jats:title>\n<jats:p>Nowadays, the majority of the population suffers from the problem of hair\nloss. It leads to disturbed mental health, lower self-confidence, and a lot more problems. A lot of the\nhair loss therapies available are not reliable and lead to recurrence and side effects after some time.\nCannabinoids (CBD) have recently become quite popular for their benefits against hair loss. CBD oil\npreparations have been used both internally and externally for oral and topical use, respectively. Due\nto the presence of the endocannabinoid system (ECS) in the body, which naturally targets CB1 and\nCB2 receptors, the control of hair fall is possible. CBD is used topically for hair loss, whereas it is\nadministered orally for the treatment and management of a medical condition, i.e., alopecia.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Aim\/Objective:<\/jats:title>\n<jats:p>The present review aimed to provide an in-depth study on hair loss and its management\nusing CBD and its associated mechanisms.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Methods:<\/jats:title>\n<jats:p>Electronic databases, such as ScienceDirect, Google Scholar, PubMed, Wiley, Springer, and\nScopus, were thoroughly searched for information about how CBD is used, how it works, and what\nrole it plays in treating alopecia and hair loss.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results:<\/jats:title>\n<jats:p>This review has highlighted the use of CBD-based hair loss therapy, and described various\ntypes of hair loss and their treatments. This review also details the phytocannabinoids and the potential\nmechanisms of CBD's activity against hair loss and alopecia.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>The data obtained from the literature regarding CBD and hair loss provide a scientific\nbasis for CBD use in alopecia. Additionally, a more precise and comprehensive study concerning\nCBD needs to be carried out at the pre-clinical and clinical levels.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1570163820666230720153607","type":"journal-article","created":{"date-parts":[[2023,7,21]],"date-time":"2023-07-21T06:25:11Z","timestamp":1689920711000},"update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["CBD: A Potential Lead against Hair Loss, Alopecia, and its Potential\nMechanisms"],"prefix":"10.2174","volume":"21","author":[{"given":"Pranay","family":"Wal","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Pranveer Singh Institute of Technology (Pharmacy) NH19 Bhaunti Kanpur, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ankita","family":"Wal","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Pranveer Singh Institute of Technology (Pharmacy) NH19 Bhaunti Kanpur, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"ref=1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.4103\/0974-2077.178536","volume":"9","author":"Gupta M.","year":"2016","unstructured":"Gupta M.; Mysore V.; Classifications of patterned hair loss: a review. J Cutan Aesthet Surg  2016,9(1),3-12","journal-title":"J Cutan Aesthet Surg"},{"key":"ref=2","doi-asserted-by":"publisher","first-page":"626","DOI":"10.4103\/0378-6323.116732","volume":"79","author":"Singal A.","year":"2013","unstructured":"Singal A.; Sonthalia S.; Verma P.; Female pattern hair loss. Indian J Dermatol Venereol Leprol  2013,79(5),626-640","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"ref=3","doi-asserted-by":"publisher","first-page":"95","DOI":"10.4103\/ijt.ijt_46_17","volume":"9","author":"Wu W.","year":"2017","unstructured":"Wu W.; Wirya C.T.; Wu K.; Classification of male-pattern hair loss. Int J Trichology  2017,9(3),95-100","journal-title":"Int J Trichology"},{"key":"ref=4","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1111\/j.0909-752X.2006.00202.x","volume":"12","author":"Van Neste D.","year":"2006","unstructured":"Van Neste D.; Female patients complaining about hair loss: documentation of defective scalp hair dynamics with contrast-enhanced phototrichogram. Skin Res Technol  2006,12(2),83-88","journal-title":"Skin Res Technol"},{"key":"ref=5","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/S0733-8635(05)70470-8","volume":"15","author":"Stough D.B.","year":"1997","unstructured":"Stough D.B.; Miner J.E.; Male pattern alopecia. Surgical options. Dermatol Clin  1997,15(4),609-622","journal-title":"Dermatol Clin"},{"key":"ref=6","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1007\/s12020-017-1280-y","volume":"57","author":"Lolli F.","year":"2017","unstructured":"Lolli F.; Pallotti F.; Rossi A.; Fortuna M.C.; Caro G.; Lenzi A.; Sansone A.; Lombardo F.; Androgenetic alopecia: a review. Endocrine  2017,57(1),9-17","journal-title":"Endocrine"},{"key":"ref=7","doi-asserted-by":"publisher","first-page":"3759","DOI":"10.1111\/jocd.14537","volume":"20","author":"Nestor M.S.","year":"2021","unstructured":"Nestor M.S.; Ablon G.; Gade A.; Han H.; Fischer D.L.; Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics. J Cosmet Dermatol  2021,20(12),3759-3781","journal-title":"J Cosmet Dermatol"},{"key":"ref=8","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1517\/17460441.2015.1009892","volume":"10","author":"Santos Z.","year":"2015","unstructured":"Santos Z.; Avci P.; Hamblin M.R.; Drug discovery for alopecia: gone today, hair tomorrow. Expert Opin Drug Discov  2015,10(3),269-292","journal-title":"Expert Opin Drug Discov"},{"key":"ref=9","doi-asserted-by":"publisher","first-page":"1295","DOI":"10.1517\/14656561003752730","volume":"11","author":"Rathnayake D.","year":"2010","unstructured":"Rathnayake D.; Sinclair R.; Male androgenetic alopecia. Expert Opin Pharmacother  2010,11(8),1295-1304","journal-title":"Expert Opin Pharmacother"},{"key":"ref=10","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/j.ijwd.2018.05.001","volume":"4","author":"Fabbrocini G.","year":"2018","unstructured":"Fabbrocini G.; Cantelli M.; Masar\u00e0 A.; Annunziata M.C.; Marasca C.; Cacciapuoti S.; Female pattern hair loss: A clinical, pathophysiologic, and therapeutic review. Int J Womens Dermatol  2018,4(4),203-211","journal-title":"Int J Womens Dermatol"},{"key":"ref=11","first-page":"39","volume":"11","author":"Sehgal V.N.","year":"2013","unstructured":"Sehgal V.N.; Srivastava G.; Aggarwal A.K.; Midha R.; Hair biology and its comprehensive sequence in female pattern baldness: diagnosis and treatment modalities--Part I. Skinmed  2013,11(1),39-45","journal-title":"Skinmed"},{"key":"ref=12","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1159\/000509001","volume":"6","author":"Egger A.","year":"2020","unstructured":"Egger A.; Resnik S.R.; Aickara D.; Maranda E.; Kaiser M.; Wikramanayake T.C.; Jimenez J.J.; Examining the safety and efficacy of low-level laser therapy for male and female pattern hair loss: a review of the literature. Skin Appendage Disord  2020,6(5),259-267","journal-title":"Skin Appendage Disord"},{"key":"ref=13","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.jdermsci.2012.10.001","volume":"69","author":"Nakamura M.","year":"2013","unstructured":"Nakamura M.; Schneider M.R.; Schmidt-Ullrich R.; Paus R.; Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and\/or structure: An update. J Dermatol Sci  2013,69(1),6-29","journal-title":"J Dermatol Sci"},{"key":"ref=14","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1016\/j.jid.2020.12.006","volume":"141","author":"Stone R.C.","year":"2021","unstructured":"Stone R.C.; Aviv A.; Paus R.; Telomere dynamics and telomerase in the biology of hair follicles and their stem cells as a model for aging research. J Invest Dermatol  2021,141(4),1031-1040","journal-title":"J Invest Dermatol"},{"key":"ref=15","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1007\/s40265-016-0629-5","volume":"76","author":"Kelly Y.","year":"2016","unstructured":"Kelly Y.; Blanco A.; Tosti A.; Androgenetic alopecia: an update of treatment options. Drugs  2016,76(14),1349-1364","journal-title":"Drugs"},{"key":"ref=16","first-page":"457","volume":"17","author":"Lee S.W.","year":"2018","unstructured":"Lee S.W.; Juhasz M.; Mobasher P.; Ekelem C.; Mesinkovska N.A.; A systematic review of topical finasteride in the treatment of androgenetic alopecia in men and women. J Drugs Dermatol  2018,17(4),457-463","journal-title":"J Drugs Dermatol"},{"key":"ref=17","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1080\/13543784.2019.1568989","volume":"28","author":"Ocampo-Garza J.","year":"2019","unstructured":"Ocampo-Garza J.; Griggs J.; Tosti A.; New drugs under investigation for the treatment of alopecias. Expert Opin Investig Drugs  2019,28(3),275-284","journal-title":"Expert Opin Investig Drugs"},{"key":"ref=18","doi-asserted-by":"publisher","first-page":"jocd.12930","DOI":"10.1111\/jocd.12930","volume":"18","author":"Dhariwala M.Y.","year":"2019","unstructured":"Dhariwala M.Y.; Ravikumar P.; An overview of herbal alternatives in androgenetic alopecia. J Cosmet Dermatol  2019,18(4),jocd.12930","journal-title":"J Cosmet Dermatol"},{"key":"ref=19","doi-asserted-by":"publisher","first-page":"6135","DOI":"10.3390\/ijms22116135","volume":"22","author":"Bagood M.D.","year":"2021","unstructured":"Bagood M.D.; Isseroff R.R.; TRPV1: role in skin and skin diseases and potential target for improving wound healing. Int J Mol Sci  2021,22(11),6135","journal-title":"Int J Mol Sci"},{"key":"ref=20","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1111\/brv.12151","volume":"90","author":"Geyfman M.","year":"2015","unstructured":"Geyfman M.; Plikus M.V.; Treffeisen E.; Andersen B.; Paus R.; Resting no more: re-defining telogen, the maintenance stage of the hair growth cycle. Biol Rev Camb Philos Soc  2015,90(4),1179-1196","journal-title":"Biol Rev Camb Philos Soc"},{"key":"ref=21","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1111\/ics.12489","volume":"40","author":"Madaan A.","year":"2018","unstructured":"Madaan A.; Verma R.; Singh A.T.; Jaggi M.; Review of Hair Follicle Dermal Papilla cells as in vitro screening model for hair growth. Int J Cosmet Sci  2018,40(5),429-450","journal-title":"Int J Cosmet Sci"},{"key":"ref=22","doi-asserted-by":"publisher","first-page":"528","DOI":"10.4103\/ijdvl.IJDVL_671_17","volume":"84","author":"Dogra S.","year":"2018","unstructured":"Dogra S.; Vinay K.; Sawatkar G.U.; Hair manifestations of endocrine diseases: A brief review. Indian J Dermatol Venereol Leprol  2018,84(5),528-538","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"ref=23","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1097\/FTD.0000000000000667","volume":"42","author":"Carlier J.","year":"2020","unstructured":"Carlier J.; Huestis M.A.; Zaami S.; Pichini S.; Busard\u00f2 F.P.; Monitoring perinatal exposure to cannabis and synthetic cannabinoids. Ther Drug Monit  2020,42(2),194-204","journal-title":"Ther Drug Monit"},{"key":"ref=24","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1055\/a-1420-5780","volume":"88","author":"Martinelli G.","year":"2022","unstructured":"Martinelli G.; Magnavacca A.; Fumagalli M.; Dell\u02bcAgli M, Piazza S, Sangiovanni E. Dissecting the role of phytocannabinoids. Planta Med  2022,88(7),492-506","journal-title":"Planta Med"},{"key":"ref=25","doi-asserted-by":"publisher","first-page":"51","DOI":"10.4103\/ijt.ijt_99_17","volume":"10","author":"Darwin E.","year":"2018","unstructured":"Darwin E.; Hirt P.; Fertig R.; Doliner B.; Delcanto G.; Jimenez J.; Alopecia areata: Review of epidemiology, clinical features, pathogenesis, and new treatment options. Int J Trichology  2018,10(2),51-60","journal-title":"Int J Trichology"},{"key":"ref=26","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1111\/exd.12504","volume":"23","author":"Gensure R.C.","year":"2014","unstructured":"Gensure R.C.; Parathyroid hormone-related peptide and the hair cycle - is it the agonists or the antagonists that cause hair growth? Exp Dermatol  2014,23(12),865-867","journal-title":"Exp Dermatol"},{"key":"ref=27","doi-asserted-by":"publisher","first-page":"918","DOI":"10.3390\/molecules24050918","volume":"24","author":"T\u00f3th K.","year":"2019","unstructured":"T\u00f3th K.; \u00c1d\u00e1m D.; B\u00edr\u00f3 T.; Ol\u00e1h A.; Cannabinoid Signaling in the Skin: Therapeutic Potential of the \u201cC(ut)annabinoid\u201d System. Molecules  2019,24(5),918","journal-title":"Molecules"},{"key":"ref=28","doi-asserted-by":"publisher","first-page":"1258","DOI":"10.1111\/jdv.12915","volume":"29","author":"Rossi A.","year":"2015","unstructured":"Rossi A.; Iorio A.; Di Nunno D.; Priolo L.; Fortuna M.C.; Garelli V.; Carlesimo M.; Calvieri S.; Mari E.; Conditions simulating androgenetic alopecia. J Eur Acad Dermatol Venereol  2015,29(7),1258-1264","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref=29","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1002\/jvc2.53","volume":"1","author":"Dominguez-Santas M.","year":"2022","unstructured":"Dominguez-Santas M.; Diaz-Guimaraens B.; Saceda-Corralo D.; Hermosa-Gelbard A.; Mu\u00f1oz-Moreno Arrones O.; Pindado-Ortega C.; Fernandez-Nieto D.; Jimenez-Cauhe J.; Ortega-Quijano D.; Suarez-Valle A.; Jaen-Olasolo P.; Va\u00f1o-Galvan S.; The state\u2010of\u2010the\u2010art in the management of androgenetic alopecia: A review of new therapies and treatment algorithms. JEADV Clin Pract  2022,1(3),176-185","journal-title":"JEADV Clin Pract"},{"key":"ref=30","doi-asserted-by":"publisher","first-page":"263","DOI":"10.4103\/ijdvl.IJDVL_262_17","volume":"84","author":"Rojas-Mart\u00ednez A.","year":"2018","unstructured":"Rojas-Mart\u00ednez A.; Martinez-Jacobo L.; Villarreal-Villarreal C.D.; Ortiz-L\u00f3pez R.; Ocampo-Candiani J.; Genetic and molecular aspects of androgenetic alopecia. Indian J Dermatol Venereol Leprol  2018,84(3),263-268","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"ref=31","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1046\/j.1365-2230.2002.01085.x","volume":"27","author":"Birch M.P.","year":"2002","unstructured":"Birch M.P.; Lalla S.C.; Messenger A.G.; Female pattern hair loss. Clin Exp Dermatol  2002,27(5),383-388","journal-title":"Clin Exp Dermatol"},{"key":"ref=32","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1111\/dth.12390","volume":"29","author":"Rossi A.","year":"2016","unstructured":"Rossi A.; Anzalone A.; Fortuna M.C.; Caro G.; Garelli V.; Pranteda G.; Carlesimo M.; Multi-therapies in androgenetic alopecia: review and clinical experiences. Dermatol Ther  2016,29(6),424-432","journal-title":"Dermatol Ther"},{"key":"ref=33","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.jaad.2017.02.054","volume":"77","author":"Adil A.","year":"2017","unstructured":"Adil A.; Godwin M.; The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis. J Am Acad Dermatol  2017,77(1),136-141.e5","journal-title":"J Am Acad Dermatol"},{"key":"ref=34","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.1097\/DSS.0000000000001894","volume":"45","author":"Gupta A.K.","year":"2019","unstructured":"Gupta A.K.; Cole J.; Deutsch D.P.; Everts P.A.; Niedbalski R.P.; Panchaprateep R.; Rinaldi F.; Rose P.T.; Sinclair R.; Vogel J.E.; Welter R.J.; Zufelt M.D.; Puig C.J.; Platelet-rich plasma as a treatment for androgenetic alopecia. Dermatol Surg  2019,45(10),1262-1273","journal-title":"Dermatol Surg"},{"key":"ref=35","doi-asserted-by":"publisher","DOI":"10.1038\/jidsymp.2013.4","author":"Hordinsky M.K.","year":"2013","unstructured":"Hordinsky M.K.; Overview of alopecia areata. In Journal of Investigative Dermatology Symposium Proceedings  2013","journal-title":"In Journal of Investigative Dermatology Symposium Proceedings"},{"key":"ref=36","first-page":"358","volume":"15","author":"Otlewska A.","year":"2019","unstructured":"Otlewska A.; Otlewska A.; Szpotowicz G.; Alopecia areata. Paediatrics and Family Medicine  2019,15(4),358","journal-title":"Paediatrics and Family Medicine"},{"key":"ref=37","doi-asserted-by":"publisher","first-page":"72","DOI":"10.12788\/j.sder.2015.0160","volume":"34","author":"Hordinsky M.","year":"2015","unstructured":"Hordinsky M.; Junqueira L.; Alopecia areata update. Semin Cutan Med Surg  2015,34(2),72-75","journal-title":"Semin Cutan Med Surg"},{"key":"ref=38","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1007\/s11046-016-0058-8","volume":"182","author":"Hay R.J.","year":"2017","unstructured":"Hay R.J.; Tinea capitis: current status. Mycopathologia  2017,182(1-2),87-93","journal-title":"Mycopathologia"},{"key":"ref=39","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/S0001-7310(08)74630-1","volume":"99","author":"Rebollo N.","year":"2008","unstructured":"Rebollo N.; L\u00f3pez-Barcenas A.P.; Arenas R.; Ti\u00f1a de la cabeza. Actas Dermosifiliogr  2008,99(2),91-100","journal-title":"Actas Dermosifiliogr"},{"key":"ref=40","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1007\/s11046-017-0181-1","volume":"182","author":"Brito-Santos F.","year":"2017","unstructured":"Brito-Santos F.; Figueiredo-Carvalho M.H.G.; Coelho R.A.; Sales A.; Almeida-Paes R.; Tinea capitis by Microsporum audouinii: case reports and review of published global literature 2000\u20132016. Mycopathologia  2017,182(11-12),1053-1060","journal-title":"Mycopathologia"},{"key":"ref=41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.7573\/dic.2020-5-6","volume":"9","author":"Leung A.K.C.","year":"2020","unstructured":"Leung A.K.C.; Lam J.M.; Leong K.F.; Hon K.L.; Tinea corporis: an updated review. Drugs Context  2020,9,1-12","journal-title":"Drugs Context"},{"key":"ref=42","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1159\/000495909","volume":"5","author":"Alkeswani A.","year":"2019","unstructured":"Alkeswani A.; Cantrell W.; Elewski B.; Treatment of tinea capitis. Skin Appendage Disord  2019,5(4),201-210","journal-title":"Skin Appendage Disord"},{"key":"ref=43","doi-asserted-by":"publisher","first-page":"16","DOI":"10.5070\/D30519T0B9","volume":"18","author":"Zaraa I.","year":"2012","unstructured":"Zaraa I.; Hawilo A.; Trojjet S.; Euch D.E.; Mokni M.; Osman A.B.; Tinea capitis in infants in their first 2 years of life: A 12-year study and a review of the literature. Dermatol Online J  2012,18(7),16","journal-title":"Dermatol Online J"},{"key":"ref=44","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1111\/j.1525-1470.2012.01808.x","volume":"30","author":"Kojima R.","year":"2013","unstructured":"Kojima R.; Fujiwara T.; Matsuda A.; Narita M.; Matsubara O.; Nonoyama S.; Ohya Y.; Saito H.; Matsumoto K.; Factors associated with steroid phobia in caregivers of children with atopic dermatitis. Pediatr Dermatol  2013,30(1),29-35","journal-title":"Pediatr Dermatol"},{"key":"ref=45","doi-asserted-by":"publisher","first-page":"2264","DOI":"10.1111\/jdv.15088","volume":"32","author":"Gupta A.K.","year":"2018","unstructured":"Gupta A.K.; Mays R.R.; Versteeg S.G.; Piraccini B.M.; Shear N.H.; Piguet V.; Tosti A.; Friedlander S.F.; Tinea capitis in children: a systematic review of management. J Eur Acad Dermatol Venereol  2018,32(12),2264-2274","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref=46","doi-asserted-by":"publisher","first-page":"583","DOI":"10.2147\/CCID.S200471","volume":"12","author":"Rebora A.","year":"2019","unstructured":"Rebora A.; Telogen effluvium: a comprehensive review. Clin Cosmet Investig Dermatol  2019,12,583-590","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"ref=47","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/j.jdermsci.2021.01.007","volume":"101","author":"Chien Yin G.O.","year":"2021","unstructured":"Chien Yin G.O.; Siong-See J.L.; Wang E.C.E; Telogen Effluvium \u2013 a review of the science and current obstacles. J Dermatol Sci  2021,101(3),156-163","journal-title":"J Dermatol Sci"},{"key":"ref=48","first-page":"WE01","volume":"9","author":"Malkud S.","year":"2015","unstructured":"Malkud S.; Telogen effluvium: a review. J Clin Diagn Res  2015,9(9),WE01-WE03","journal-title":"J Clin Diagn Res"},{"key":"ref=49","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1590\/S0365-05962012000600010","volume":"87","author":"Werner B.","year":"2012","unstructured":"Werner B.; Mulinari-Brenner F.; Clinical and histological challenge in the differential diagnosis of diffuse alopecia: female androgenetic alopecia, telogen effluvium and alopecia areata - part II. An Bras Dermatol  2012,87(6),884-890","journal-title":"An Bras Dermatol"},{"key":"ref=50","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1517\/14656566.2012.685160","volume":"13","author":"Miteva M.","year":"2012","unstructured":"Miteva M.; Tosti A.; Treatment options for alopecia: an update, looking to the future. Expert Opin Pharmacother  2012,13(9),1271-1281","journal-title":"Expert Opin Pharmacother"},{"key":"ref=51","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1016\/j.mcna.2021.04.002","volume":"105","author":"Jamerson T.A.","year":"2021","unstructured":"Jamerson T.A.; Aguh C.; An approach to patients with alopecia. Med Clin North Am  2021,105(4),599-610","journal-title":"Med Clin North Am"},{"key":"ref=52","first-page":"47","volume":"149","author":"Rebora A.","year":"2014","unstructured":"Rebora A.; Telogen effluvium revisited. G Ital Dermatol Venereol  2014,149(1),47-54","journal-title":"G Ital Dermatol Venereol"},{"key":"ref=53","doi-asserted-by":"publisher","first-page":"136","DOI":"10.4103\/psychiatry.IndianJPsychiatry_529_18","volume":"61","author":"Grant J.","year":"2019","unstructured":"Grant J.; Trichotillomania (hair pulling disorder). Indian J Psychiatry  2019,61(7)(Suppl. 1),136","journal-title":"Indian J Psychiatry"},{"key":"ref=54","doi-asserted-by":"publisher","first-page":"e13466","DOI":"10.1111\/dth.14366","volume":"34","author":"Torales J.","year":"2021","unstructured":"Torales J.; Ruiz D\u00edaz N.; Ventriglio A.; Castaldelli-Maia J.M.; Barrios I.; Garc\u00eda O.; Navarro R.; Gonz\u00e1lez-Urbieta I.; O\u2019Higgins M.; Jafferany M.; HAIR\u2010PULLING disorder (Trichotillomania): Etiopathogenesis, diagnosis and treatment in a nutshell. Dermatol Ther  2021,34(1),e13466","journal-title":"Dermatol Ther"},{"key":"ref=55","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.euroneuro.2005.07.004","volume":"16","author":"Gupta Y.K.","year":"2006","unstructured":"Gupta Y.K.; Briyal S.; Protective effect of vineatrol against kainic acid induced seizures, oxidative stress and on the expression of heat shock proteins in rats. Eur Neuropsychopharmacol  2006,16(2),85-91","journal-title":"Eur Neuropsychopharmacol"},{"key":"ref=56","doi-asserted-by":"publisher","first-page":"88","DOI":"10.12788\/j.sder.0007","volume":"32","author":"Huynh M.","year":"2013","unstructured":"Huynh M.; Gavino A.C.; Magid M.; Trichotillomania. Semin Cutan Med Surg  2013,32(2),88-94","journal-title":"Semin Cutan Med Surg"},{"key":"ref=57","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.2147\/NDT.S79554","volume":"11","author":"\u00d6zten E.","year":"2015","unstructured":"\u00d6zten E.; H\u0131zl\u0131 Sayar G.; Ka\u011fan G.; I\u015f\u0131k S.; Karamustafal\u0131o\u011flu O.; Eryilmaz G.; The relationship of psychological trauma with trichotillomania and skin picking. Neuropsychiatr Dis Treat  2015,11,1203-1210","journal-title":"Neuropsychiatr Dis Treat"},{"key":"ref=58","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1007\/s13555-018-0256-z","volume":"8","author":"Ciso\u0144 H.","year":"2018","unstructured":"Ciso\u0144 H.; Ku\u015b A.; Popowicz E.; Szyca M.; Reich A.; Trichotillomania and trichophagia: modern diagnostic and therapeutic methods. Dermatol Ther (Heidelb)  2018,8(3),389-398","journal-title":"Dermatol Ther (Heidelb)"},{"key":"ref=59","doi-asserted-by":"publisher","first-page":"1455","DOI":"10.1080\/14656566.2020.1761324","volume":"21","author":"Baczynski C.","year":"2020","unstructured":"Baczynski C.; Sharma V.; Pharmacotherapy for trichotillomania in adults. Expert Opin Pharmacother  2020,21(12),1455-1466","journal-title":"Expert Opin Pharmacother"},{"key":"ref=60","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1590\/1516-4446-2019-0471","volume":"42","author":"Lamothe H.","year":"2020","unstructured":"Lamothe H.; Baleyte J.M.; Mallet L.; Pelissolo A.; Trichotillomania is more related to Tourette disorder than to obsessive-compulsive disorder. Br J Psychiatry  2020,42(1),87-104","journal-title":"Br J Psychiatry"},{"key":"ref=61","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1080\/09546634.2016.1246704","volume":"28","author":"Haskin A.","year":"2017","unstructured":"Haskin A.; Kwatra S.G.; Aguh C.; Breaking the cycle of hair breakage: pearls for the management of acquired trichorrhexis nodosa. J Dermatolog Treat  2017,28(4),322-326","journal-title":"J Dermatolog Treat"},{"key":"ref=62","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/j.det.2018.05.009","volume":"36","author":"Rudnicka L.","year":"2018","unstructured":"Rudnicka L.; Olszewska M.; Wa\u015bkiel A.; Rakowska A.; Trichoscopy in hair shaft disorders. Dermatol Clin  2018,36(4),421-430","journal-title":"Dermatol Clin"},{"key":"ref=63","doi-asserted-by":"publisher","first-page":"109","DOI":"10.4103\/ijdvl.IJDVL_1019_16","volume":"84","author":"Kudligi C.","year":"2018","unstructured":"Kudligi C.; Kuntoji V.; Bhagwat P.; Asati D.; Bansal A.; The tricky \u201ctrichs\u201d in dermatology! Indian J Dermatol Venereol Leprol  2018,84(1),109-113","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"ref=64","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/s42649-021-00067-6","volume":"51","author":"Bhattarai D.","year":"2021","unstructured":"Bhattarai D.; Banday A.Z.; Sadanand R.; Arora K.; Kaur G.; Sharma S.; Rawat A.; Hair microscopy: an easy adjunct to diagnosis of systemic diseases in children. Appl Microsc  2021,51(1),18","journal-title":"Appl Microsc"},{"key":"ref=65","first-page":"31","volume":"100","author":"Taylor S.C.","year":"2017","unstructured":"Taylor S.C.; Barbosa V.; Burgess C.; Heath C.; McMichael A.J.; Ogunleye T.; Callender V.; Hair and scalp disorders in adult and pediatric patients with skin of color. Cutis  2017,100(1),31-35","journal-title":"Cutis"},{"key":"ref=66","doi-asserted-by":"publisher","first-page":"604","DOI":"10.4103\/0378-6323.116728","volume":"79","author":"Kanwar A.","year":"2013","unstructured":"Kanwar A.; Narang T.; Anagen effluvium. Indian J Dermatol Venereol Leprol  2013,79(5),604-612","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"ref=67","doi-asserted-by":"publisher","first-page":"e13168","DOI":"10.1111\/dth.13168","volume":"33","author":"Jafferany M.","year":"2020","unstructured":"Jafferany M.; Patel A.; Trichopsychodermatology: the psychiatric and psychosocial aspects of hair disorders. Dermatol Ther  2020,33(1),e13168","journal-title":"Dermatol Ther"},{"key":"ref=68","doi-asserted-by":"publisher","first-page":"157","DOI":"10.15570\/actaapa.2020.32","volume":"29","author":"Kecelj B.","year":"2020","unstructured":"Kecelj B.; Kecelj Leskovec N.; \u017dgavec B.; A case report and differential diagnosis of pruritic pretibial skin lesions. Acta Dermatovenerol Alp Panonica Adriat  2020,29(3),157-159","journal-title":"Acta Dermatovenerol Alp Panonica Adriat"},{"key":"ref=69","doi-asserted-by":"publisher","DOI":"10.1002\/9781118590638.ch10","author":"Yeager C","year":"2013","unstructured":"Yeager C; Olsen EA; Hair disorders associated with anticancer agents. Dermatologic Principles and Practice in Oncology: Conditions of the Skin, Hair, and Nails in Cancer Patients  2013","journal-title":"Dermatologic Principles and Practice in Oncology: Conditions of the Skin, Hair, and Nails in Cancer Patients"},{"key":"ref=70","author":"Burstein S.","year":"2015","unstructured":"Burstein S.; CBD Receptor Binding Signaling Events Downstream Events. Bioorg Med Chem  2015","journal-title":"Bioorg Med Chem"},{"key":"ref=71","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2018\/1691428","volume":"2018","author":"Pellati F.","year":"2018","unstructured":"Pellati F.; Borgonetti V.; Brighenti V.; Biagi M.; Benvenuti S.; Corsi L.; Cannabis sativa L. and nonpsychoactive cannabinoids: their chemistry and role against oxidative stress, inflammation, and cancer. BioMed Res Int  2018,2018,1-15","journal-title":"BioMed Res Int"},{"key":"ref=72","doi-asserted-by":"publisher","first-page":"422","DOI":"10.3389\/fphar.2017.00422","volume":"8","author":"Morales P.","year":"2017","unstructured":"Morales P.; Reggio P.H.; Jagerovic N.; An overview on medicinal chemistry of synthetic and natural derivatives of cannabidiol. Front Pharmacol  2017,8,422","journal-title":"Front Pharmacol"},{"key":"ref=73","doi-asserted-by":"publisher","first-page":"112163","DOI":"10.1016\/j.ejmech.2020.112163","volume":"192","author":"Li H.","year":"2020","unstructured":"Li H.; Liu Y.; Tian D.; Tian L.; Ju X.; Qi L.; Wang Y.; Liang C.; Overview of cannabidiol (CBD) and its analogues: Structures, biological activities, and neuroprotective mechanisms in epilepsy and Alzheimer\u2019s disease. Eur J Med Chem  2020,192,112163","journal-title":"Eur J Med Chem"},{"key":"ref=74","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.4155\/fmc.09.93","volume":"1","author":"Nagarkatti P.","year":"2009","unstructured":"Nagarkatti P.; Pandey R.; Rieder S.A.; Hegde V.L.; Nagarkatti M.; Cannabinoids as novel anti-inflammatory drugs. Future Med Chem  2009,1(7),1333-1349","journal-title":"Future Med Chem"},{"key":"ref=75","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1159\/000510896","volume":"6","author":"Vincenzi C.","year":"2020","unstructured":"Vincenzi C.; Tosti A.; Efficacy and tolerability of a shampoo containing broad-spectrum cannabidiol in the treatment of scalp inflammation in patients with mild to moderate scalp psoriasis or seborrheic dermatitis. Skin Appendage Disord  2020,6(6),355-361","journal-title":"Skin Appendage Disord"},{"key":"ref=76","doi-asserted-by":"publisher","first-page":"384","DOI":"10.3390\/agriculture11050384","volume":"11","author":"Valizadehderakhshan M.","year":"2021","unstructured":"Valizadehderakhshan M.; Shahbazi A.; Kazem-Rostami M.; Todd M.S.; Bhowmik A.; Wang L.; Extraction of cannabinoids from Cannabis sativa L.(Hemp). Agriculture  2021,11(5),384","journal-title":"Agriculture"},{"key":"ref=77","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1007\/s13311-015-0377-3","volume":"12","author":"Ibeas Bih C.","year":"2015","unstructured":"Ibeas Bih C.; Chen T.; Nunn A.V.W.; Bazelot M.; Dallas M.; Whalley B.J.; Molecular targets of cannabidiol in neurological disorders. Neurotherapeutics  2015,12(4),699-730","journal-title":"Neurotherapeutics"},{"key":"ref=78","doi-asserted-by":"publisher","first-page":"1593","DOI":"10.1152\/physrev.00002.2016","volume":"96","author":"Ligresti A.","year":"2016","unstructured":"Ligresti A.; De Petrocellis L.; Di Marzo V.; From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology. Physiol Rev  2016,96(4),1593-1659","journal-title":"Physiol Rev"},{"key":"ref=79","doi-asserted-by":"publisher","first-page":"9472","DOI":"10.3390\/ijms22179472","volume":"22","author":"Lowe H.","year":"2021","unstructured":"Lowe H.; Toyang N.; Steele B.; Bryant J.; Ngwa W.; The endocannabinoid system: A potential target for the treatment of various diseases. Int J Mol Sci  2021,22(17),9472","journal-title":"Int J Mol Sci"},{"key":"ref=80","doi-asserted-by":"publisher","first-page":"S238","DOI":"10.1016\/j.jid.2017.07.261","volume":"137","author":"Szab\u00f3 I.L.","year":"2017","unstructured":"Szab\u00f3 I.L.; Herczeg-Lisztes E.; Szollosi A.G.; Szegedi A.; B\u00edr\u00f3 T.; Ol\u00e1h A.; 263 (-)-cannabidiol differentially influences hair growth. J Invest Dermatol  2017,137(10),S238","journal-title":"J Invest Dermatol"},{"key":"ref=81","doi-asserted-by":"publisher","first-page":"1479","DOI":"10.1111\/j.1476-5381.2010.01166.x","volume":"163","author":"De Petrocellis L.","year":"2011","unstructured":"De Petrocellis L.; Ligresti A.; Moriello A.S.; Allar\u00e0 M.; Bisogno T.; Petrosino S.; Stott C.G.; Di Marzo V.; Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. Br J Pharmacol  2011,163(7),1479-1494","journal-title":"Br J Pharmacol"},{"key":"ref=82","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1007\/s13311-015-0374-6","volume":"12","author":"Di Marzo V.","year":"2015","unstructured":"Di Marzo V.; Piscitelli F.; The endocannabinoid system and its modulation by phytocannabinoids. Neurotherapeutics  2015,12(4),692-698","journal-title":"Neurotherapeutics"},{"key":"ref=83","doi-asserted-by":"publisher","first-page":"927","DOI":"10.2147\/CCID.S286411","volume":"13","author":"Baswan S.M.","year":"2020","unstructured":"Baswan S.M.; Klosner A.E.; Glynn K.; Rajgopal A.; Malik K.; Yim S.; Stern N.; Therapeutic potential of cannabidiol (CBD) for skin health and disorders. Clin Cosmet Investig Dermatol  2020,13,927-942","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"ref=84","author":"Leinow L.","year":"2017","unstructured":"Leinow L.; Birnbaum J.;  CBD: A Patient\u2019s Guide to Medicinal Cannabis--Healing without the High  2017","journal-title":"CBD: A Patient\u2019s Guide to Medicinal Cannabis--Healing without the High"},{"key":"ref=85","doi-asserted-by":"publisher","first-page":"237","DOI":"10.2174\/157488611798280924","volume":"6","author":"Bergamaschi M.M.","year":"2011","unstructured":"Bergamaschi M.M.; Queiroz R.H.; Zuardi A.W.; Crippa J.A.; Safety and side effects of cannabidiol, a Cannabis sativa constituent. Curr Drug Saf  2011,6(4),237-249","journal-title":"Curr Drug Saf"},{"key":"ref=86","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/978-1-59259-710-9_27","volume":"1999","author":"Hollister LE","year":"1999","unstructured":"Hollister LE; Interactions of Marihuana and THC with Other Drugs: What We Don\u2019t, But Should, Know. Marihuana and medicine  1999,1999,273-277","journal-title":"Marihuana and medicine"}],"container-title":["Current Drug Discovery Technologies"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.eurekaselect.com\/article\/download?doi=10.2174\/1570163820666230720153607","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/218949\/article","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/article\/download?doi=10.2174\/1570163820666230720153607","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T06:13:00Z","timestamp":1714630380000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurekaselect.com\/218949\/article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":86,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["LiveAll1"],"URL":"https:\/\/doi.org\/10.2174\/1570163820666230720153607","relation":{},"ISSN":["1570-1638"],"issn-type":[{"type":"print","value":"1570-1638"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2023-02-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-24","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e200723218949"}}