{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T07:22:26Z","timestamp":1747207346299,"version":"3.40.5"},"reference-count":24,"publisher":"Bentham Science Publishers Ltd.","issue":"4","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["CRR"],"published-print":{"date-parts":[[2023,8,3]]},"abstract":"<jats:sec>\n<jats:title>Introduction:<\/jats:title>\n<jats:p>Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease with variable clinical presentation, including neuropsychiatric manifestations. It has a different di-agnostic approach and several different therapeutic options.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Case Report:<\/jats:title>\n<jats:p>We describe a case of a young woman who first presented with arthritis, serositis, and pancreatitis, and was treated with mycophenolate mofetil initially. The patient presented with neu-rological symptoms suggestive of neuropsychiatric manifestations three weeks later, confirmed by Brain Magnetic Resonance Imaging (MRI). The treatment was changed to cyclophosphamide; how-ever, the day after the infusion, she developed status epilepticus and was admitted to the intensive care unit. Repeated brain MRI revealed Posterior Reversible Encephalopathy Syndrome (PRES). Cyclophosphamide was discontinued and rituximab was initiated. The patient\u2019s neurological mani-festations improved, and she was discharged after 25 days of use.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>Immunosuppressive agents, such as cyclophosphamide have been described as a po-tential risk factor for PRES; however, it is not clear from the available literature whether cyclo-phosphamide therapy is just a marker of more severe SLE or a true risk factor for PRES.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1573397119666230420111517","type":"journal-article","created":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T12:57:01Z","timestamp":1681995421000},"page":"508-514","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Neuropsychiatric Systemic Lupus Erythematosus and Posterior Reversible\nEncephalopathy Syndrome in a Young Woman: A Case Report"],"prefix":"10.2174","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5060-3884","authenticated-orcid":true,"given":"Yasser","family":"Mohammed Bawazir","sequence":"first","affiliation":[{"name":"Associate Professor of Medicine, Department of Medicine, King Abdulaziz University, Jeddah, KSA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neda'a","family":"Wasim Anshasi","sequence":"additional","affiliation":[{"name":"Internal Medicine Resident, King Abdulaziz University Hospital, Jeddah, KSA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"ref=1","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/j.rdc.2021.04.011","volume":"47","author":"Aringer M.","year":"2021","unstructured":"Aringer M.; Johnson S.R.; Systemic Lupus erythematosus classification and diagnosis. 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