{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T07:47:59Z","timestamp":1791445679517,"version":"4.3.3"},"reference-count":0,"publisher":"Bentham Science Publishers Ltd.","issue":"2","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["CCR"],"published-print":{"date-parts":[[2021,5,7]]},"abstract":"<jats:sec>\n<jats:title>:<\/jats:title>\n<jats:p>Hydralazine, an arterial vasodilator, is a widely used medication for the management of\nhypertension and heart failure, especially for patients who cannot tolerate the use of ACEIs or\nARBs. It is generally well-tolerated and has a safe profile in pregnancy. However, hydralazine can\ninduce immune-mediated side effects, such as hydralazine-induced lupus and less commonly hydralazine-\ninduced ANCA vasculitis. The latter most commonly affects the kidneys with or without\nother organ involvement. There are several cases reported in the literature of hydralazine-induced\nANCA associated vasculitis (AAV) that have pulmonary manifestations, also known as hydralazine-\ninduced pulmonary-renal syndrome (PRS), a condition with a high risk of mortality. We are\nreporting a case of Hydralazine-induced ANCA associated glomerulonephritis with severe diffuse\nalveolar hemorrhage (DAH). In addition, we will review the current literature and discuss the importance\nof prompt diagnosis and early management to decrease mortality and morbidity associated\nwith this serious condition.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1573403x16666200518092814","type":"journal-article","created":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T08:16:00Z","timestamp":1589789760000},"page":"182-187","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Hydralazine-Induced ANCA Associated Vasculitis (AAV) Presenting with Pulmonary-Renal Syndrome (PRS): A Case Report with Literature Review"],"prefix":"10.2174","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7175-3881","authenticated-orcid":true,"given":"Karim","family":"Doughem","sequence":"first","affiliation":[{"name":"University of Texas Health Science Center at Houston, Houston, TX 77030, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8370-5764","authenticated-orcid":true,"given":"Ayman","family":"Battisha","sequence":"additional","affiliation":[{"name":"University of Massachusetts Medical School-Baystate, Springfield, MA 01655, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3107-3152","authenticated-orcid":true,"given":"Omar","family":"Sheikh","sequence":"additional","affiliation":[{"name":"University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6946-858X","authenticated-orcid":true,"given":"Lakshmi","family":"Konduru","sequence":"additional","affiliation":[{"name":"University of Texas Health Science Center at Houston, Houston, TX 77030, United 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States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","container-title":["Current Cardiology Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/eurekaselect.com\/article\/download\/182070","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/182070\/article","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eurekaselect.com\/article\/download\/182070","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,11]],"date-time":"2021-05-11T20:31:45Z","timestamp":1620765105000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurekaselect.com\/182070\/article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,7]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,5,7]]}},"alternative-id":["LiveAll1"],"URL":"https:\/\/doi.org\/10.2174\/1573403x16666200518092814","relation":{},"ISSN":["1573-403X"],"issn-type":[{"value":"1573-403X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5,7]]},"assertion":[{"value":"Peer 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