{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T07:14:21Z","timestamp":1760426061472,"version":"3.40.5"},"reference-count":0,"publisher":"Bentham Science Publishers Ltd.","issue":"8","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["CMIR"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:sec>\n<jats:title>Background:<\/jats:title>\n<jats:p>The typical findings of COVID-19 pneumonia include multilobar groundglass\nopacities and consolidation areas observed predominantly in the basal and peripheral parts of\nboth lungs in computed tomography.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Objective:<\/jats:title>\n<jats:p>The current study aimed to correlate indeterminate lesions of COVID-19 pneumonia detected\non computed tomography with the results of the reverse transcription-polymerase chain reaction\n(RT-PCR) test.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Methods:<\/jats:title>\n<jats:p>Patients with high-resolution computed tomography images that were reported to contain\nindeterminate lesions in terms of COVID-19 pneumonia were included retrospectively in the study.\nThe lesions were categorized and the patterns were classified. The RT-PCR-positive and the RTPCR-\nnegative patients were compared. P&lt;0.05 was accepted as the statistical significance limit.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results:<\/jats:title>\n<jats:p>The RT-PCR-positive patients exhibited a higher rate of peripheral lesions. Limited consolidation\nareas were not detected in the RT-PCR-positive patients. In the RT-PCR-negative patients,\nthe rates of acinar nodules and the tree-in-bud pattern were significantly higher. The RTPCR-\nnegative patients had higher nodular contour features and lesion coalescence. In the subgroup\nconsisting of lesions with ground-glass opacities and\/or ground-glass opacity around the nodule,\nthe rate of nodular contour positivity was significantly higher in the RT-PCR- positive patients.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>COVID-19 pneumonia should be suspected when peripheral indeterminate lesions are\ndetected. When indeterminate lesions, such as tree-in-bud pattern, acinar nodules and limited consolidation\narea are detected, alternative diagnoses should be considered first, even if there are\nground glass opacities accompanying these lesions.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1573405618666220111095357","type":"journal-article","created":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T05:16:28Z","timestamp":1641964588000},"page":"862-868","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Correlation of Indeterminate Lesions of COVID-19 Pneumonia Detected\non Computed Tomography with RT-PCR Results"],"prefix":"10.2174","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7765-4323","authenticated-orcid":true,"given":"Nevin","family":"Aydin","sequence":"first","affiliation":[{"name":"Department of Radiology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8327-1302","authenticated-orcid":true,"given":"\u00c7a\u011fatay","family":"Cihan","sequence":"additional","affiliation":[{"name":"Department of Radiology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9772-6777","authenticated-orcid":true,"given":"Tercan","family":"Us","sequence":"additional","affiliation":[{"name":"Department of\nMicrobiology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2243-7644","authenticated-orcid":true,"given":"Yasemin","family":"\u00d6z","sequence":"additional","affiliation":[{"name":"Department of\nMicrobiology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, 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Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7486-4157","authenticated-orcid":true,"given":"Sinan","family":"Erginel","sequence":"additional","affiliation":[{"name":"Department of Chest Diseases,\nFaculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4563-2776","authenticated-orcid":true,"given":"Emel","family":"Kurt","sequence":"additional","affiliation":[{"name":"Department of Chest Diseases,\nFaculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8849-193X","authenticated-orcid":true,"given":"G\u00fcnt\u00fcl\u00fc","family":"Ak","sequence":"additional","affiliation":[{"name":"Department of Chest Diseases,\nFaculty of Medicine, Eskisehir Osmangazi University, Eskisehir, 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