{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T10:12:06Z","timestamp":1789726326918,"version":"4.0.1"},"reference-count":0,"publisher":"Bentham Science Publishers Ltd.","issue":"3","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["CDS"],"published-print":{"date-parts":[[2021,11,30]]},"abstract":"<jats:sec>\n<jats:title>Background:<\/jats:title>\n<jats:p>A rare type of cutaneous adverse drug reaction (CADR), lichenoid drug\neruption (LDE), can be associated with ethambutol.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Case Report:<\/jats:title>\n<jats:p>A 60-year-old woman with spinal tuberculosis received multiple anti-TB medications\nand developed rashes after 3 months of the treatments. A skin biopsy from the posterior auricular\narea confirmed lichenoid dermatitis, and the Naranjo causality assessment indicated ethambutol\nas a probable cause of LDE in the patient. The rashes slowly improved after discontinuation of\nethambutol. Unfortunately, the residual of brown hyperpigmentation on the body still persisted for\nover 16 months.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>The medications were reduced to isoniazid 300 mg\/day and rifampicin 450 mg \/day\nas planned for another 3 months. This case report points out the essentials of early recognition of\nethambutol LDE by health care professionals.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1574886315666201217095950","type":"journal-article","created":{"date-parts":[[2020,12,18]],"date-time":"2020-12-18T07:26:13Z","timestamp":1608276373000},"page":"296-298","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Ethambutol Induced Lichenoid Drug Eruption: A Case Report"],"prefix":"10.2174","volume":"16","author":[{"given":"Thitaree","family":"Yuyaem","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Nangrong Hospital, Buriram, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8327-4282","authenticated-orcid":true,"given":"Patcharaporn","family":"Sudchada","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chutika","family":"Srisuttiyakorn","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Phramongkutklao Hospital, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jirapan","family":"Juntawong","sequence":"additional","affiliation":[{"name":"Department of Medicine, Nangrong Hospital, Buriram, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naruemon","family":"Khanngern","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Nangrong Hospital, Buriram, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natwara","family":"Watcharapokin","sequence":"additional","affiliation":[{"name":"Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pitchayakorn","family":"Chansangiam","sequence":"additional","affiliation":[{"name":"Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","container-title":["Current Drug Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/eurekaselect.com\/article\/download\/189199","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/189199\/article","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eurekaselect.com\/article\/download\/189199","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,15]],"date-time":"2021-12-15T09:50:48Z","timestamp":1639561848000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurekaselect.com\/189199\/article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,30]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,11,30]]}},"alternative-id":["LiveAll1"],"URL":"https:\/\/doi.org\/10.2174\/1574886315666201217095950","relation":{},"ISSN":["1574-8863"],"issn-type":[{"value":"1574-8863","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11,30]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2020-08-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-09","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}