{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T04:58:27Z","timestamp":1687928307641},"reference-count":59,"publisher":"Bentham Science Publishers Ltd.","issue":"4","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["RRCT"],"published-print":{"date-parts":[[2021,1,12]]},"abstract":"<jats:sec>\n<jats:title>Background and Aims:<\/jats:title>\n<jats:p>Liver cirrhosis (LC) of any origin has always been a source of\nseveral emergencies for physicians working at the Emergency Department (ER). LC patients can\npresent with several complications that are sometimes difficult to recognize and treat.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title \/>\n<jats:p>Thus, we reviewed the literature evidence for the diagnosis and management of several LC related\nemergencies.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Methods:<\/jats:title>\n<jats:p> We conducted a search on the main medical databases for papers, reviews, metanalyses,\ncase series, and RCTs using the following keywords and their associations: liver cirrhosis, variceal\nhemorrhage, ascites, hepatic encephalopathy, spontaneous bacterial peritonitis, hepato-renal syndrome,\nemergency.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results:<\/jats:title>\n<jats:p> Main LC emergencies are upper gastrointestinal hemorrhage, decompensated ascites and\nspontaneous bacterial peritonitis, hepatic encephalopathy, hepato-renal syndrome. Their management\nis partly medical and interventional. Very often, the final cure of some complications, such as\nhepato-renal syndrome, is represented by liver transplantation.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions:<\/jats:title>\n<jats:p> Although LC prevalence is going to fall in the following years, due to HBV and HCV\noptimized treatments, its complications represent a significant admission percentage at the ER and\nchallenge for physicians\u2019 skills.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1574887115666200603160816","type":"journal-article","created":{"date-parts":[[2020,6,4]],"date-time":"2020-06-04T05:13:36Z","timestamp":1591247616000},"page":"331-338","update-policy":"http:\/\/dx.doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Liver Cirrhosis Complications Management at the Emergency Department"],"prefix":"10.2174","volume":"15","author":[{"given":"Emidio","family":"Scarpellini","sequence":"first","affiliation":[{"name":"Internal Medicine Unit, \u201cMadonna del Soccorso\u201d General Hospital, San Benedetto del Tronto, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmelo","family":"Luigiano","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, ASST Santi Paolo e Carlo, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluca","family":"Svegliati-Baroni","sequence":"additional","affiliation":[{"name":"Gastroenterology Clinic, \u201cRiuniti University Hospital\u201d, Polytechnics University of Marche, Ancona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Dumitrascu","sequence":"additional","affiliation":[{"name":"Gastroenterology Unit, Cluj University, Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiziana","family":"Larussa","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University \u201cMagna Gr\u00e6cia\u201d, Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Santori","sequence":"additional","affiliation":[{"name":"Gastroenterology Clinic, \u201cRiuniti University Hospital\u201d, Polytechnics University of Marche, Ancona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Luzza","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University \u201cMagna Gr\u00e6cia\u201d, Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ludovico","family":"Abenavoli","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University \u201cMagna Gr\u00e6cia\u201d, Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"ref=1","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1001\/jama.2013.13805","volume":"310","author":"Murray C.J.","year":"2013","unstructured":"Murray C.J.; 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