{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:08:11Z","timestamp":1791389291977,"version":"4.3.3"},"reference-count":0,"publisher":"Bentham Science Publishers Ltd.","issue":"1","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["RRCT"],"published-print":{"date-parts":[[2021,2,15]]},"abstract":"<jats:sec>\n<jats:title>Background:<\/jats:title>\n<jats:p>Hemorrhoids are vascular cushions underlying the distal rectal mucosa\nand contributing to approximately 15\u201320% of the resting anal pressure with a complete closure of\nthe anal canal. They can become pathological (hemorrhoidal disease, HD) being the most common\ncause of painless rectal bleeding during defecation with or without prolapsing anal tissue. The treatment\nof HD must be tailored to both the severity of disease and patient\u2019s expectation.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Methods:<\/jats:title>\n<jats:p>A narrative review of all the most relevant papers present on the three major databases\n(PUBMED, EMBASE and WEB OF SCIENCE) regarding conservative treatment was conducted.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results:<\/jats:title>\n<jats:p>Conservative treatment is effective in managing the majority of patients complaining of\nearly stages of the disease. Dietary and lifestyle modifications are the first therapeutic step necessary\nto achieve a regular defecation with soft stool whereas oral phlebotonic drugs can help to control\nsymptoms. The use of topical medications, particularly during the acute phase or in the post-operative\nperiod can also be beneficial for all patients complaining of HD.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>Despite a large number of available products in the market and the high incidence of\nHD, very few randomized controlled trials have been carried out and most of the studies are uncontrolled\ncase series. Larger and better designed studies are necessary to establish the real benefit of\nall types of drugs for the treatment of early stages of HD.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1574887115666201021150144","type":"journal-article","created":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T04:15:32Z","timestamp":1603426532000},"page":"87-90","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Conservative Treatment of Hemorrhoidal Disease"],"prefix":"10.2174","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1204-7175","authenticated-orcid":true,"given":"Emanuela","family":"Stratta","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery, S. Rita Clinic, Vercelli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaetano","family":"Gallo","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, S. Rita Clinic, Vercelli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Trompetto","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, S. Rita Clinic, Vercelli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","container-title":["Reviews on Recent Clinical Trials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/eurekaselect.com\/article\/download\/187085","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/187085\/article","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eurekaselect.com\/article\/download\/187085","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,16]],"date-time":"2021-02-16T04:24:34Z","timestamp":1613449474000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurekaselect.com\/187085\/article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,15]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,2,15]]}},"alternative-id":["LiveAll1"],"URL":"https:\/\/doi.org\/10.2174\/1574887115666201021150144","relation":{},"ISSN":["1574-8871"],"issn-type":[{"value":"1574-8871","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2,15]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2020-05-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-19","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}