{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T19:43:07Z","timestamp":1769197387752,"version":"3.49.0"},"reference-count":0,"publisher":"Bentham Science Publishers Ltd.","issue":"1","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["PRI"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>In endemic regions of brucellosis, childhood brucellosis includes up to one-third of all cases of human brucellosis.\nThe main source of infection in children is consumption of unpasteurized dairy products and traditional local foods\ncontaining dairy products. The older boys are more involved in animal care. Boys are more commonly infected than girls.\nCommon symptoms and signs include fever, arthralgia, sweating, peripheral arthritis and splenomegaly. Peripheral arthritis\nespecially monoarthritis is more common and the most commonly affected joints are hip and knee. All organs may involve\nduring the course of the disease. Isolation of Brucella spp. from the blood, bone marrow or other tissue fluids is the\nhallmark of diagnosis. Serologic tests are the main tools of diagnosis of brucellosis in endemic regions. Standard agglutination\ntest (SAT) with titers &gt;1:160 and the 2-mercaptoethanol (2ME) test &amp;ge;1:80 are suggestive of active infection. Children\nolder than 8 years should be treated with doxycycline for 45 days or 8 weeks plus gentamicin for 7 or 5 days respectively\nor doxycycline for 45 days and streptomycin for 14 days. Also doxycycline plus rifampin or cotrimoxazole plus rifampin\nfor 45 days may be alternative regimens. Cotrimoxazole plus rifampin for six weeks is the regimen of choice for\nthe treatment of patients younger than 8 years old. Gentamicin for 5 days plus cotrimoxazole for six weeks may be a suitable\nalternative regimen. The article presented few of the patents associated with Brucellosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2174\/1574891x11308010008","type":"journal-article","created":{"date-parts":[[2013,5,7]],"date-time":"2013-05-07T09:28:55Z","timestamp":1367918935000},"page":"42-46","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Update on Childhood Brucellosis"],"prefix":"10.2174","volume":"8","author":[{"given":"Mohammad","family":"R.H. Roushan","sequence":"first","affiliation":[{"name":"Infectious Diseases Research Center, Babol Medical University, Babol, 4717641367, Iran.,Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"J.S. Amiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","container-title":["Recent Patents on Anti-Infective Drug Discovery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.eurekaselect.com\/article\/download?doi=10.2174\/1574891X11308010008","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/107317\/article","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/article\/download?doi=10.2174\/1574891X11308010008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T10:51:50Z","timestamp":1761389510000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurekaselect.com\/107317\/article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["LiveAll1"],"URL":"https:\/\/doi.org\/10.2174\/1574891x11308010008","relation":{},"ISSN":["1574-891X"],"issn-type":[{"value":"1574-891X","type":"print"}],"subject":[],"published":{"date-parts":[[2014,4]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Double blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-02-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}