{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T15:23:14Z","timestamp":1791300194076,"version":"4.1.0"},"reference-count":24,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2018,10,31]],"date-time":"2018-10-31T00:00:00Z","timestamp":1540944000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["clinical-practice-and-epidemiology-in-mental-health.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["CPEMH"],"published-print":{"date-parts":[[2018,10,31]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Emotional stress is frequently associated with otologic symptoms as tinnitus and dizziness. Stress can contribute to the beginning or worsening of tinnitus.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The objective of the study is to evaluate the presence of stress symptoms in patients with chronic, subjective tinnitus, and correlate its presence to annoyance associated with tinnitus.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This is a cross-sectional study. One hundred and eighty patients with chronic, subjective tinnitus were included. Patients answered the Tinnitus Handicap Inventory (THI) to evaluate the impact of tinnitus in the quality of life and answered the Lipp's inventory symptoms of stress for adults (ISSL). The data obtained was organized using Excel\u00ae 2010, mean values, linear regression and p-value were calculated.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Of the 180 patients included in the study, 117 (65%) had stress symptoms, 52 of the 117 (44%) were in the resistance phase and 23 of the 117 (20%) in the exhaustion phase, the remaining was in the alert phase. There was a clear progressive increase in stress as THI raised, with more impact of tinnitus in quality of life.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The presence of stress symptoms, measured by ISSL was observed in most of our patients with chronic subjective tinnitus, specially in the resistance and exhaustion phases and it is directly associated with tinnitus annoyance.<\/jats:p>\n                <\/jats:sec>","DOI":"10.2174\/1745017901814010264","type":"journal-article","created":{"date-parts":[[2018,11,5]],"date-time":"2018-11-05T09:59:12Z","timestamp":1541411952000},"page":"264-269","update-policy":"https:\/\/doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Tinnitus: The Sound of Stress?"],"prefix":"10.2174","volume":"14","author":[{"given":"Patricia","family":"Ciminelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoela","family":"Palmeira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro Giovanni","family":"Carta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah Cristina","family":"Beirith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle Levitan","family":"Nigri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco Andr\u00e9","family":"Mezzasalma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio Egidio","family":"Nardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","reference":[{"key":"ref1","unstructured":"Lipp MEN. \n                    O Stress no Brasil: Pesquisas avan\u00e7adas \n                    \n                    \n                    2004."},{"key":"ref2","unstructured":"Colman AM. \n                    Oxford Dictionary of Psychology \n                    \n                    \n                    2009."},{"key":"ref3","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1007\/s10865-007-9145-0","volume":"31","author":"Heinecke K.","year":"2008","unstructured":"Heinecke K, Weise C, Schwarz K, Rief W. \n                    Physiological and psychological stress reactivity in chronic tinnitus. \n                    J Behav Med  \n                    2008; \n                    31\n                    (3)\n                    : 179-88.","journal-title":"J. Behav. Med."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1016\/S0272-7358(01)00124-6","volume":"22","author":"Andersson G.","year":"2002","unstructured":"Andersson G. \n                    Psychological aspects of tinnitus and the application of cognitive-behavioral therapy. \n                    Clin Psychol Rev  \n                    2002; \n                    22\n                    (7)\n                    : 977-90.","journal-title":"Clin. Psychol. Rev."},{"key":"ref5","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1111\/j.1365-2273.2004.00879.x","volume":"29","author":"Reynolds P.","year":"2004","unstructured":"Reynolds P, Gardner D, Lee R. \n                    Tinnitus and psychological morbidity: A cross-sectional study to investigate psychological morbidity in tinnitus patients and its relationship with severity of symptoms and illness perceptions. \n                    Clin Otolaryngol Allied Sci  \n                    2004; \n                    29\n                    (6)\n                    : 628-34.","journal-title":"Clin. Otolaryngol. 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Res."},{"key":"ref7","doi-asserted-by":"publisher","first-page":"2177","DOI":"10.1007\/s00405-013-2715-6","volume":"271","author":"Gomaa M.A.","year":"2014","unstructured":"Gomaa MA, Elmagd MH, Elbadry MM, Kader RM. \n                    Depression, anxiety and stress scale in patients with tinnitus and hearing loss. \n                    Eur Arch Otorhinolaryngol  \n                    2014; \n                    271\n                    (8)\n                    : 2177-84.","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref8","first-page":"6","volume":"11","author":"Mazurek B","year":"2012","unstructured":"Mazurek B, Haupt H, Olze H, Szczepek AJ. \n                    Stress and tinnitus-from bedside to bench and back. \n                    Front Syst Neurosci   \n                    2012; \n                    11\n                    : 6-47.","journal-title":"Front Syst Neurosci."},{"key":"ref9","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1097\/AUD.0b013e31822229bd","volume":"32","author":"Baigi A.","year":"2011","unstructured":"Baigi A, Oden A, Almlid-Larsen V, Barren\u00e4s ML, Holgers KM. \n                    Tinnitus in the general population with a focus on noise and stress: A public health study. \n                    Ear Hear  \n                    2011; \n                    32\n                    (6)\n                    : 787-9.","journal-title":"Ear Hear."},{"key":"ref10","first-page":"11","volume":"23","author":"Hasson D","year":"2011","unstructured":"Hasson D, Theorell T, Wall\u00e9n MB, Leineweber C, Canlon B. \n                    Stress and prevalence of hearing problems in the Swedish working population. \n                    BMC Public Health  \n                    2011; \n                    23\n                    : 11-130.","journal-title":"BMC Public Health."},{"key":"ref11","doi-asserted-by":"publisher","first-page":"3071","DOI":"10.3390\/ijerph7083071","volume":"7","author":"Mazurek B.","year":"2010","unstructured":"Mazurek B, Olze H, Haupt H, Szczepek AJ. \n                    The more the worse: The grade of noise-induced hearing loss associates with the severity of tinnitus. \n                    Int J Environ Res Public Health  \n                    2010; \n                    7\n                    (8)\n                    : 3071-9.","journal-title":"Int. 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Tinnitus J."},{"key":"ref14","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/S0022-3999(96)00171-7","volume":"41","author":"Budd R.J.","year":"1996","unstructured":"Budd RJ, Pugh R. \n                    Tinnitus coping style and its relationship to tinnitus severity and emotional distress. \n                    J Psychosom Res  \n                    1996; \n                    41\n                    (4)\n                    : 327-35.","journal-title":"J. Psychosom. Res."},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.1016\/0022-3999(95)00512-9","volume":"39","author":"Budd R.J.","year":"1995","unstructured":"Budd RJ, Pugh R. \n                    The relationship between locus of control, tinnitus severity, and emotional distress in a group of tinnitus sufferers. \n                    J Psychosom Res  \n                    1995; \n                    39\n                    (8)\n                    : 1015-8.","journal-title":"J. Psychosom. Res."},{"key":"ref16","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1097\/00006842-198903000-00009","volume":"51","author":"Kirsch C.A.","year":"1989","unstructured":"Kirsch CA, Blanchard EB, Parnes SM. \n                    Psychological characteristics of individuals high and low in their ability to cope with tinnitus. \n                    Psychosom Med  \n                    1989; \n                    51\n                    (2)\n                    : 209-17.","journal-title":"Psychosom. Med."},{"key":"ref17","first-page":"41","volume":"6","author":"Schmitt C.","year":"2000","unstructured":"Schmitt C, Patak M, Kr\u00f6ner-Herwig B. \n                    Stress and the onset of sudden hearing loss and tinnitus. \n                    Int Tinnitus J  \n                    2000; \n                    6\n                    (1)\n                    : 41-9.","journal-title":"Int. Tinnitus J."},{"key":"ref18","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/S0149-7634(03)00071-X","volume":"27","author":"Horner K.C.","year":"2003","unstructured":"Horner KC. \n                    The emotional ear in stress. \n                    Neurosci Biobehav Rev  \n                    2003; \n                    27\n                    (5)\n                    : 437-46.","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref19","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/S0378-5955(00)00235-5","volume":"152","author":"Sahley T.L.","year":"2001","unstructured":"Sahley TL, Nodar RH. \n                    A biochemical model of peripheral tinnitus. \n                    Hear Res  \n                    2001; \n                    152\n                    (1-2)\n                    : 43-54.","journal-title":"Hear. Res."},{"key":"ref20","first-page":"20","volume":"5","author":"Datzov E.","year":"1999","unstructured":"Datzov E, Danev S, Haralanov H, Naidenova V, Sachanska T, Savov A. \n                    Tinnitus, heart rate variability, and some biochemical indicators. \n                    Int Tinnitus J  \n                    1999; \n                    5\n                    (1)\n                    : 20-3.","journal-title":"Int. Tinnitus J."},{"key":"ref21","doi-asserted-by":"publisher","first-page":"201","DOI":"10.3109\/03005369909090101","volume":"33","author":"Andersson G.","year":"1999","unstructured":"Andersson G, Lyttkens L. \n                    A meta-analytic review of psychological treatments for tinnitus. \n                    Br J Audiol  \n                    1999; \n                    33\n                    (4)\n                    : 201-10.","journal-title":"Br. J. Audiol."},{"key":"ref22","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/S0022-3999(01)00281-1","volume":"52","author":"Weber C.","year":"2002","unstructured":"Weber C, Arck P, Mazurek B, Klapp BF. \n                    Impact of a relaxation training on psychometric and immunologic parameters in tinnitus sufferers. \n                    J Psychosom Res  \n                    2002; \n                    52\n                    (1)\n                    : 29-33.","journal-title":"J. Psychosom. Res."},{"key":"ref23","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1097\/01.psy.0000174174.38908.c6","volume":"67","author":"Rief W.","year":"2005","unstructured":"Rief W, Weise C, Kley N, Martin A. \n                    Psychophysiologic treatment of chronic tinnitus: A randomized clinical trial. \n                    Psychosom Med  \n                    2005; \n                    67\n                    (5)\n                    : 833-8.","journal-title":"Psychosom. Med."},{"key":"ref24","first-page":"209","volume":"6","author":"Fornaro M","year":"2010","unstructured":"Fornaro M, Martino M. \n                    Tinnitus psychopharmacology: A comprehensive review of its pathomechanisms and management  \n                    2010; \n                    6\n                    : 209-18.","journal-title":"Tinnitus psychopharmacology: A comprehensive review of its pathomechanisms and management."}],"container-title":["Clinical Practice &amp; Epidemiology in Mental Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/clinical-practice-and-epidemiology-in-mental-health.com\/contents\/volumes\/V14\/CPEMH-14-264\/CPEMH-14-264.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/clinical-practice-and-epidemiology-in-mental-health.com\/contents\/volumes\/V14\/CPEMH-14-264\/CPEMH-14-264.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/clinical-practice-and-epidemiology-in-mental-health.com\/contents\/volumes\/V14\/CPEMH-14-264\/CPEMH-14-264.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T07:18:31Z","timestamp":1554362311000},"score":1,"resource":{"primary":{"URL":"https:\/\/clinical-practice-and-epidemiology-in-mental-health.com\/VOLUME\/14\/PAGE\/264\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,31]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,10,31]]}},"alternative-id":["CPEMH-14-264"],"URL":"https:\/\/doi.org\/10.2174\/1745017901814010264","relation":{},"ISSN":["1745-0179"],"issn-type":[{"value":"1745-0179","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10,31]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2018-4-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-9-19","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-2","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}