{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:36:15Z","timestamp":1753889775629,"version":"3.41.2"},"reference-count":0,"publisher":"Bentham Science Publishers Ltd.","issue":"7","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["IDDT"],"published-print":{"date-parts":[[2021,12,31]]},"abstract":"<jats:sec>\n<jats:title>:<\/jats:title>\n<jats:p>A novel coronavirus, SARS- CoV-2 (2019-nCoV), emerged in December 2019 as an immediate\nglobal challenge. Comprehensive efforts at the present time are focused simultaneously on\ncontaining the spread of this virus and extenuating the ill effects. There is an immediate need for\ndrugs that can help before a vaccine can be developed. Researchers are endeavoring to find antiviral\ntherapies specific to the virus. As the condition is an emerging, rapidly evolving situation and\ndevelopment of new drugs is a long process, and is unfeasible to face the immediate global challenge.\nStrategy to reposition the previously used drugs can prove to be effective to combat this difficult\nto treat pandemic. Several drugs such as Hydroxychloroquine, Umifenovir, Remdesivir, Lopinavir\/\nRitonavir, interferon, Darunavir, Favipiravir, Nitazoxanide, etc. are currently undergoing clinical\nstudies to test the safety and efficacy of the drug against this pandemic. The present review\ngives a snapshot look at the current clinical experience with repurposed antiviral drugs.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1871526520666201218151841","type":"journal-article","created":{"date-parts":[[2020,12,21]],"date-time":"2020-12-21T05:56:05Z","timestamp":1608530165000},"update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pharmacological Strategies for COVID-19 - A Review of the Most Promising Repurposed Antiviral Drugs"],"prefix":"10.2174","volume":"21","author":[{"given":"Deepti","family":"Chopra","sequence":"first","affiliation":[{"name":"Department of Pharmacology, Government Institute of Medical Sciences, Greater Noida, Uttar Pradesh 201310,India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaspreet K","family":"Boparai","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Government Institute of Medical Sciences, Greater Noida, Uttar Pradesh 201310,India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0030-9601","authenticated-orcid":true,"given":"Bharti","family":"Bhandari","sequence":"additional","affiliation":[{"name":"Department of Physiology, Government Institute of Medical Sciences, Greater Noida, Uttar Pradesh,India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anurag","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Government Institute of Medical Sciences, Greater Noida, Uttar Pradesh 201310,India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rakesh","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Government Institute of Medical Sciences, Greater Noida, Uttar Pradesh 201310,India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","container-title":["Infectious Disorders - Drug Targets"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/eurekaselect.com\/article\/download\/189260","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.eurekaselect.com\/189260\/article","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/eurekaselect.com\/article\/download\/189260","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T06:22:13Z","timestamp":1641363733000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.eurekaselect.com\/189260\/article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,31]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,12,31]]}},"alternative-id":["LiveAll1"],"URL":"https:\/\/doi.org\/10.2174\/1871526520666201218151841","relation":{},"ISSN":["1871-5265"],"issn-type":[{"type":"print","value":"1871-5265"}],"subject":[],"published":{"date-parts":[[2021,12,31]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2020-05-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-08","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e160921189260"}}