{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T20:24:28Z","timestamp":1790281468291,"version":"4.1.0"},"reference-count":0,"publisher":"Bentham Science Publishers Ltd.","issue":"8","license":[{"start":{"date-parts":[[2020,12,24]],"date-time":"2020-12-24T00:00:00Z","timestamp":1608768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["CNSNDDT"],"published-print":{"date-parts":[[2020,12,24]]},"abstract":"<jats:sec>\n<jats:title\/>\n<jats:p>Impulse Control Disorders (ICDs) and related disorders are common side effects of dopaminergic\ntreatment in Parkinson\u2019s Disease (PD) and are associated with negative effects on mental and\nphysical health, quality of life and interpersonal relationships. Current management options are limited,\nas a reduction of dopaminergic medication often leads to worsening of motor symptoms or dopamine agonist\nwithdrawal syndrome. The aim of this review was to investigate if ICDs improve, worsen, or remain\nstable after Subthalamic Nucleus Deep Brain Stimulation (STN-DBS). We reviewed retrospective,\nprospective and randomized-controlled studies published between 2000 and 2019 examining the effect\nof STN-DBS on one or more ICDs. The number of participants, time of follow-up, methods used to\nmeasure ICDs, type of ICDs, the incidence of ICDs before STN-DBS, the incidence of improvement\n(remission or reduction) of ICDs after STN-DBS, the incidence of de novo ICDs after STN-DBS, stimulation\nparameters, lead position, change in motor score and change in medication are reported for each\nstudy. Available studies suggest that ICDs improve after STN-DBS in most patients and that persisting\nnew-onset ICDs induced by STN-DBS are rare. However, more randomized-controlled studies are needed\nto confirm the findings and to further investigate the underlying mechanisms.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1871527319666200720105553","type":"journal-article","created":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T09:13:11Z","timestamp":1595322791000},"page":"611-617","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Management of Impulse Control Disorders with Subthalamic Nucleus Deep Brain Stimulation in Parkinson\u2019s Disease"],"prefix":"10.2174","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2268-8021","authenticated-orcid":true,"given":"Deborah","family":"Amstutz","sequence":"first","affiliation":[{"name":"Department of Neurology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9306-8332","authenticated-orcid":true,"given":"Steffen","family":"Paschen","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospital Schleswig-Holstein, Christian-Albrechts-University, Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2952-6383","authenticated-orcid":true,"given":"Martin Lenard","family":"Lachenmayer","sequence":"additional","affiliation":[{"name":"Department of Neurology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4454-462X","authenticated-orcid":true,"given":"Marie Elise","family":"Maradan-Gachet","sequence":"additional","affiliation":[{"name":"Department of Neurology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4176-9196","authenticated-orcid":true,"given":"G\u00fcnther","family":"Deuschl","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospital Schleswig-Holstein, Christian-Albrechts-University, Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3508-7295","authenticated-orcid":true,"given":"Paul","family":"Krack","sequence":"additional","affiliation":[{"name":"Department of Neurology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1709-2963","authenticated-orcid":true,"given":"Ines","family":"Debove","sequence":"additional","affiliation":[{"name":"Department of Neurology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","container-title":["CNS &amp; Neurological Disorders - Drug Targets"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/eurekaselect.com\/article\/download\/183933","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurekaselect.com\/183933\/article","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eurekaselect.com\/article\/download\/183933","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T04:57:49Z","timestamp":1625029069000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurekaselect.com\/183933\/article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,24]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,12,24]]}},"alternative-id":["LiveAll1"],"URL":"https:\/\/doi.org\/10.2174\/1871527319666200720105553","relation":{},"ISSN":["1871-5273"],"issn-type":[{"value":"1871-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12,24]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2020-04-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-29","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}