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After a few\nyears (2012), Pandeya modified Dimmock\u2019s concept by adding one more pharmacophoric feature as\nan electron donor in the previously suggested pharmacophoric arrangement of the anticonvulsant. As a\nresult, numerous scientists designed anticonvulsant drugs based on Dimmock\u2019s and Pandeya\u2019s concept.\nIn addition, marketed anticonvulsant preparation containing Riluzole, Phenobarbital, Progabide,\nRalitoline, etc., also holds the suggested pharmacophores by Dimmock and Pandeya\u2019s pharmacophoric\nconcept. This review mainly focuses on the compilation of reported scientific literature in the last decade\non the pharmacophoric features of different heterocyclic anticonvulsants, which will help develop\nnew anticonvulsants.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1871527321666220401115529","type":"journal-article","created":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T18:09:36Z","timestamp":1649009376000},"page":"500-511","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Importance of Pharmacophore in Designing Anticonvulsant Agents"],"prefix":"10.2174","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9970-6040","authenticated-orcid":true,"given":"Amol","family":"Kale","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Chemistry, Seth Govind Raghunath Sable College of Pharmacy, Saswad, Pune, Maharashtra\n412301, India"},{"name":"Sudhakarrao Naik Institute of Pharmacy, Pusad, Maharashtra 445204, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2656-6208","authenticated-orcid":true,"given":"Rajendra","family":"Kakde","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra 440001, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1103-5781","authenticated-orcid":true,"given":"Smita","family":"Pawar","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry, Seth Govind Raghunath Sable College of Pharmacy, Saswad, Pune, Maharashtra\n412301, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1641-4975","authenticated-orcid":true,"given":"Vishal","family":"Jagtap","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry, Seth Govind Raghunath Sable College of Pharmacy, Saswad, Pune, Maharashtra\n412301, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8683-2745","authenticated-orcid":true,"given":"Rahul","family":"Dorugade","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry, Seth Govind Raghunath Sable College of Pharmacy, Saswad, Pune, Maharashtra\n412301, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","reference":[{"key":"ref=1","doi-asserted-by":"publisher","first-page":"3072","DOI":"10.1016\/j.bmcl.2012.03.068","volume":"22","author":"Saravanan G.","year":"2012","unstructured":"Saravanan G.; Alagarsamy V.; Prakash C.R.; Design, synthesis and anticonvulsant activities of novel 1-(substituted\/unsubstituted benzylidene)-4-(4-(6,8-dibromo-2-(methyl\/phenyl)-4-oxoquinazolin-3(4H)-yl)phenyl) semicarbazide derivatives. 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