{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T07:22:53Z","timestamp":1747207373601,"version":"3.40.5"},"reference-count":29,"publisher":"Bentham Science Publishers Ltd.","issue":"3","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["EMIDDT"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:sec>\n<jats:title\/>\n<jats:p>A 24-years old female was admitted for acute renal failure, melanoderma, hyponatremia,\nand hyperkalemia. The clinical suspicion of Addison\u2019s disease was confirmed by laboratory test and\nthe appropriate replacement therapy with corticosteroids and fludrocortisone was started. In the meantime\nprimary hypothyroidism and diabetes mellitus type 1 were disclosed and treated, thus fulfilling a\ndiagnosis of autoimmune polyendocrine syndrome type 2. Eighteen months later she was admitted for\nright-sided heart failure. The work-up allowed to diagnose pulmonary arterial hypertension. Here, we\nreport the clinical course and discuss the putative link between these two rare diseases.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1871530320666200801033106","type":"journal-article","created":{"date-parts":[[2020,8,2]],"date-time":"2020-08-02T03:47:16Z","timestamp":1596340036000},"page":"561-565","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Autoimmune Polyendocrine Syndrome Complicated by Pulmonary Hypertension"],"prefix":"10.2174","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9683-0364","authenticated-orcid":true,"given":"Olga E.","family":"Disoteo","sequence":"first","affiliation":[{"name":"ASST Grande Ospedale Metropolitano Niguarda, Diabetology Unit, Milan,Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9495-6286","authenticated-orcid":true,"given":"Benedetta","family":"Zampetti","sequence":"additional","affiliation":[{"name":"ASST Grande Ospedale Metropolitano Niguarda, Endocrinology Department, Milan,Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5804-0481","authenticated-orcid":true,"given":"Andrea","family":"Garascia","sequence":"additional","affiliation":[{"name":"ASST Grande Ospedale Metropolitano Niguarda, Cardiology Unit, Milan,Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1417-287X","authenticated-orcid":true,"given":"Roberto","family":"Attanasio","sequence":"additional","affiliation":[{"name":"IRCCS Orthopedic Institute Galeazzi, Endocrinology Service, Milan,Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0421-5589","authenticated-orcid":true,"given":"Renato","family":"Cozzi","sequence":"additional","affiliation":[{"name":"ASST Grande Ospedale Metropolitano Niguarda, Endocrinology Department, Milan,Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"author":"Neufeld M.","key":"ref=1","unstructured":"Neufeld M.; Blizzard R.M.; Polyglandular autoimmune diseases.Symposium on autoimmune aspects of endocrine disorders., 1980, pp. 357-365."},{"key":"ref=2","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1111\/j.1365-2796.2009.02090.x","volume":"265","author":"Husebye E.S.","year":"2009","unstructured":"Husebye E.S.; Perheentupa J.; Rautemaa R.; K\u00e4mpe O.; Clinical manifestations and management of patients with autoimmune polyendocrine syndrome type I. 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