{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T07:23:36Z","timestamp":1747207416829,"version":"3.40.5"},"reference-count":27,"publisher":"Bentham Science Publishers Ltd.","issue":"1","content-domain":{"domain":["eurekaselect.com"],"crossmark-restriction":true},"short-container-title":["BIOT"],"published-print":{"date-parts":[[2024,3]]},"abstract":"\nBackground:<\/jats:title>\nThe pituitary glands normally produce and stores gonadotropic\nhormones (GnH) that are responsible for ovulation and spermiation in animals. However,\nwhether fish pituitary extracts can elicit same effects in treated animals need elucidation as\na prelude to their practical usage in animals.<\/jats:p>\n<\/jats:sec>\n\nObjectives:<\/jats:title>\nThe aim of this study was to investigate the oestrus-inducing potential of the\npituitary gland extract of the Africa Catfish (Clarias gariepinus) in immature Wistar rats.<\/jats:p>\n<\/jats:sec>\n\nMethods:<\/jats:title>\nThe experiment involved the use of 18 immature female Wistar rats and 10 male\ncatfish brood stocks with the use of six Wistar rats per groups as follows: Group A had\nhuman chorionic gonadotropin (hCG) treatment. Group B had only normal saline treatment\nas the control whereas Group C had the C. gariepinus pituitary extract administration to\ninduce oestrus with treatments occurring twice six hours apart in each group.<\/jats:p>\n<\/jats:sec>\n\nResults:<\/jats:title>\nThere was an obvious expression of visible signs of heat and the presence of uterine\nhorn oedema with significant (p < 0.05) increase in reproductive tract weight and uterine\nwidth and length. However, only progesterone levels increased significantly (p < 0.05)\nin the hCG and the C. gariepinus pituitary extract treated groups compared to other assayed\nhormones.<\/jats:p>\n<\/jats:sec>\n\nConclusion:<\/jats:title>\nThese results showed that C. gariepinus pituitary extract has the capacity to induce\noestrus in Wistar rats because of its gonadotropic effects, which needs further investigations\nat higher doses and for longer exposure periods for possible oestrus induction and synchronization\nin higher mammals. Further favourable results could herald the possible patent\nof the catfish pituitary extract for either experimental or commercial use in mammals.<\/jats:p>\n<\/jats:sec>","DOI":"10.2174\/1872208317666230313153832","type":"journal-article","created":{"date-parts":[[2023,3,14]],"date-time":"2023-03-14T06:13:04Z","timestamp":1678774384000},"page":"84-92","update-policy":"https:\/\/doi.org\/10.2174\/bsp_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Gonadotropic Activity of Pituitary Extract of African Catfish,\nClarias gariepinus, in Mammals using Immature Wistar Rats as\nModels"],"prefix":"10.2174","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7215-8400","authenticated-orcid":true,"given":"Simon","family":"Azubuike Ubah","sequence":"first","affiliation":[{"name":"Department of Theriogenology, Faculty of Veterinary Medicine, University of Abuja, Abuja, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0828-5365","authenticated-orcid":true,"given":"Samson","family":"Eneojo Abalaka","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathology, Faculty of Veterinary Medicine, University of Abuja, Abuja, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5751-2096","authenticated-orcid":true,"given":"Victory","family":"Clara Asibor","sequence":"additional","affiliation":[{"name":"Department of Theriogenology, Faculty of Veterinary Medicine, University of Abuja, Abuja, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6935-3726","authenticated-orcid":true,"given":"Ebenezer","family":"Kehinde Ogundana","sequence":"additional","affiliation":[{"name":"Department of Theriogenology, Faculty of Veterinary Medicine, University of Abuja, Abuja, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9393-2899","authenticated-orcid":true,"given":"Itodo Joy","family":"Iyojo","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Faculty of Agriculture, Federal University of Lafia, Lafia, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2730-1941","authenticated-orcid":true,"given":"Oluwa","family":"Adikpe Agbonu","sequence":"additional","affiliation":[{"name":"Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, University of\nAbuja, Abuja, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2499-8605","authenticated-orcid":true,"given":"Philemon","family":"Kwinjoh Columbus","sequence":"additional","affiliation":[{"name":"Department of Theriogenology, Faculty of Veterinary Medicine, University of Abuja, Abuja, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5301-0083","authenticated-orcid":true,"given":"Kenneth","family":"Owoicho Abah","sequence":"additional","affiliation":[{"name":"Department of Theriogenology, Faculty of Veterinary Medicine, University of Abuja, Abuja, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3331-6821","authenticated-orcid":true,"given":"Christopher","family":"Ese Obudu","sequence":"additional","affiliation":[{"name":"Department of Theriogenology, Faculty of Veterinary Medicine, University of Abuja, Abuja, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4738-0701","authenticated-orcid":true,"given":"Oluwatobi","family":"Akefe Isaac","sequence":"additional","affiliation":[{"name":"Department of Veterinary Physiology, Biochemistry and Pharmacology, Faculty of\nVeterinary Medicine, University of Jos, Jos, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7828-2250","authenticated-orcid":true,"given":"Prisca","family":"Adaoma Ezinwo","sequence":"additional","affiliation":[{"name":"Department of Theriogenology, Faculty of Veterinary Medicine, University of Abuja, Abuja, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"ref=1","doi-asserted-by":"publisher","first-page":"1012","DOI":"10.1095\/biolreprod56.4.1012","volume":"56","author":"L\u00fcking J.F.C.","year":"1997","unstructured":"L\u00fcking J.F.C.; Britt J.H.; Esbenshade K.L.; Role of gonadotropin-releasing hormone pulse frequency in differential regulation of gonadotropins in the gilt. 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