{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T15:56:32Z","timestamp":1648655792748},"reference-count":29,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2010,9,28]],"date-time":"2010-09-28T00:00:00Z","timestamp":1285632000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["opencardiovascularmedicinejournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TOCMJ"],"published-print":{"date-parts":[[2010,9,28]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title> <jats:p>Internal Cardioverter Defibrillators (ICD) has been shown to decrease mortality in patients such as those with structural heart disease or at high risk of sudden cardiac death. To date there is no data regarding the clinical features, and outcomes of ICD patients in Saudi Arabia. Accordingly, we explored the clinical features and outcomes of ICD therapy among Saudis.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Methods:<\/jats:title> <jats:p>Patients who had ICD implantation in King Khalid University Hospital from November 2007 until January 2010 were enrolled.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Results:<\/jats:title> <jats:p>One hundred and eight ICD were implanted between November 2007 and February 2010. The mean age was 58.6\u00b113.2 years. The majority were male 94 (87%), the rate of Diabetes Mellitus (DM) was 58.3%, Hypertension (HTN) was 61.1%, and 63% were smokers. The mean ejection fraction (EF) was 24.5%. Of the 108 patient 90(83.3%) had ICD insertion for primary prevention and 18(16.7%) for secondary prevention. Of the 90 patients who ICD for primary prevention 62 (57.4%) had ischemic cardiomyopathy, 39(36.1%) had dilated cardiomyopathy and 7 (6.5%) had channelopathy. Over a mean follow-up of 18 months 4 (3.7%) died. <\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title> <jats:p>Our study describes for the first time patients characteristic and outcomes for ICD therapy in Saudi Arabia. Our patients are younger and have higher prevalence of risk factors that those in Western countries.<\/jats:p>\n            <\/jats:sec>","DOI":"10.2174\/1874192401004010192","type":"journal-article","created":{"date-parts":[[2010,11,5]],"date-time":"2010-11-05T04:49:46Z","timestamp":1288932586000},"page":"192-197","update-policy":"http:\/\/dx.doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Implantable Cardioverter Defibrillator Therapy: A Single Center Experience in Saudi Arabia"],"prefix":"10.2174","volume":"4","author":[{"given":"Ahmad S","family":"Hersi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"refR1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jacc.2008.02.032","volume":"51","author":"Epstein AE","year":"2008","unstructured":"Epstein AE, DiMarco JP, Ellenbogen KA, et al. \n                    ACC\/AHA\/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities \n                    J Am Coll Cardiol  \n                    2008; \n                    51\n                    : 1-62.","journal-title":"J Am Coll Cardiol"},{"key":"refR2","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1053\/euhj.2000.2476","volume":"21","author":"Connolly SJ","year":"2000","unstructured":"Connolly SJ, Hallstrom AP, Cappato R, et al. \n                    Meta-analysis of the implantable cardioverter defibrillator secondary prevention trials. 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