{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T07:53:07Z","timestamp":1762761187762},"reference-count":28,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2013,9,4]],"date-time":"2013-09-04T00:00:00Z","timestamp":1378252800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["opencardiovascularmedicinejournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TOCMJ"],"published-print":{"date-parts":[[2013,9,4]]},"abstract":"<jats:sec>\n                    <jats:title>Aim: <\/jats:title>\n                    <jats:p>While the incidence of rheumatic heart disease has declined dramatically over the last half-century, the number of valve surgeries has not changed. This study was undertaken to define the most common type of valvular heart disease requiring surgery today, and determine in-hospital surgical mortality and length-of-stay (LOS) for isolated aortic or mitral valve surgery in a United States tertiary-care hospital.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Methods: <\/jats:title>\n                    <jats:p>Patients with valve surgery between January 2002 to June 2008 at The Ohio State University Medical Center were studied. Patients only with isolated aortic or mitral valve surgery were analyzed.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Results: <\/jats:title>\n                    <jats:p>From 915 patients undergoing at least aortic or mitral valve surgery, the majority had concomitant cardiac proce-dures mostly coronary artery bypass grafting (CABG); only 340 patients had isolated aortic (n=204) or mitral (n=136) valve surgery. In-hospital surgical mortality for mitral regurgitation (n=119), aortic stenosis (n=151), aortic insufficiency (n=53) and mitral stenosis (n=17) was 2.5% (replacement 3.4%; repair 1.6%), 3.9%, 5.6% and 5.8%, respectively (p=NS). Median LOS for aortic insufficiency, aortic stenosis, mitral regurgitation, and mitral stenosis was 7, 8, 9 (replacement 11.5; repair 7) and 11 days, respectively (p&lt;0.05 for group). In-hospital surgical mortality for single valve surgery plus CABG was 10.2% (p&lt;0.005 compared to single valve surgery).\n<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Conclusions: <\/jats:title>\n                    <jats:p>Aortic stenosis and mitral regurgitation are the most common valvular lesions requiring surgery today. Surgery for isolated aortic or mitral valve disease has low in-hospital mortality with modest LOS. Concomitant CABG with valve surgery increases mortality substantially. Hospital analysis is needed to monitor quality and stimulate improvement among Institutions.<\/jats:p>\n                <\/jats:sec>","DOI":"10.2174\/1874192420130902001","type":"journal-article","created":{"date-parts":[[2013,11,29]],"date-time":"2013-11-29T02:48:17Z","timestamp":1385693297000},"page":"104-109","update-policy":"http:\/\/dx.doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Type of Valvular Heart Disease Requiring Surgery in the 21st Century: Mortality and Length-of-Stay Related to Surgery"],"prefix":"10.2174","volume":"7","author":[{"given":"Konstantinos Dean","family":"Boudoulas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yazhini","family":"Ravi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uksha","family":"Saini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gbemiga G.","family":"Sofowora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard J.","family":"Gumina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chittoor B.","family":"Sai-Sudhakar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"refR1","author":"Boudoulas KD","year":"2013","unstructured":"Boudoulas KD, Borer JS, Boudoulas H. \n                    Etiology of Valvular Heart Disease in the 21st Century. \n                    Cardiology \n                    2013.","journal-title":"Cardiology"},{"key":"refR2","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1586\/14779072.1.4.523","volume":"1","author":"Boudoulas H","year":"2003","unstructured":"Boudoulas H. \n                    Etiology of valvular heart disease. \n                    Expet Rev Cardiovasc Ther  \n                    2003; 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