{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T06:37:14Z","timestamp":1792305434895,"version":"4.4.0"},"reference-count":76,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2015,6,26]],"date-time":"2015-06-26T00:00:00Z","timestamp":1435276800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["openneurologyjournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TONEUJ"],"published-print":{"date-parts":[[2015,6,26]]},"abstract":"<jats:p>One of the oldest and probably well-known examples of cerebral palsy is the mummy of the Pharaoh Siptah about 1196\u20131190 B.C., and a letter from Hippocrates (460\u2013390 B.C.). Cerebral palsy (CP) is one of the most common congenital or acquired neurological impairments in paediatric patients, and refers to a group of children with motor disability and related functional defects. The visible core of CP is characterized by abnormal coordination of movements and\/or muscle tone which manifest<jats:italic>very early<\/jats:italic>in the development. Resulting from pre- or perinatal brain damage CP is not a progressive condition per se. However, without systematic medical and physiotherapeutic support the dystonia leads to muscle contractions and to deterioration of the handicap. Here we review the three general spastic manifestations of CP hemiplegia, diplegia and tetraplegia, describe the diagnostic procedures and delineate a time schedule for an early intervention.<\/jats:p>","DOI":"10.2174\/1874205x01509010045","type":"journal-article","created":{"date-parts":[[2015,7,10]],"date-time":"2015-07-10T04:52:50Z","timestamp":1436503970000},"page":"45-52","update-policy":"https:\/\/doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Cerebral Palsy: A Lifelong Challenge Asks for Early Intervention"],"prefix":"10.2174","volume":"9","author":[{"given":"Christos P","family":"Panteliadis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Hagel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dieter","family":"Karch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Heinemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","reference":[{"key":"refR1","unstructured":"Ikram S, Dodson A, Eds. The mummy in ancient Egypt Thames and London Hudson. 1998."},{"key":"refR2","unstructured":"Harris J, Wende E, Eds. An X-ray atlas of the royal mummies Chicago and London University of Chicago Press. 1980."},{"key":"refR3","unstructured":"Lipourlis D, Ed. The suffix in presocratic philosophy and in the Hippocratic corpus.Thessa onik Aristotle University, 1968."},{"key":"refR4","unstructured":"Lipourlis D, Ed. The suffix in presocratic philosophy and in the Hippocratic corpus.Thessal niki Aristotle University, 1968."},{"key":"refR5","first-page":"1","volume":"73","author":"Nestle W","year":"1938","unstructured":"Nestle W. Hippocratica Hermes 1938; 73 : 1-38.","journal-title":"Hermes"},{"key":"refR6","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.braindev.2012.05.003","volume":"35","author":"Panteliadis C","year":"2013","unstructured":"Panteliadis C, Panteliadis P, Vassiliady F. Hallmarks in the history of cerebral palsy From antiquity to mid-20th century Brain & Dev 2013; 35 : 285-92.","journal-title":"Brain & Dev"},{"key":"refR7","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1093\/jhmas\/44.1.56","volume":"44","author":"Accardo P","year":"1989","unstructured":"Accardo P. William John Little and Cerebral Palsy in the Nine-teenth Century J Hist Med Allied Sci 1989; 44 : 56-71.","journal-title":"J Hist Med Allied Sci"},{"key":"refR8","unstructured":"Little W, Ed. On the nature and course treatment of deformities of human frame Being a course of lectures delivered at the Royal Orthopedic Hospital in 1843 and 1844 London Logman Brown, Green and Longmanns. 1853."},{"key":"refR9","unstructured":"Osler W, Ed. The cerebral palsies of children a clinical study from the infirmary for nervous diseases Philadelphia Blakiston P. 1889."},{"key":"refR10","author":"Nothnagel H","year":"1897","unstructured":"Nothnagel H, Freud S. Die infantile Cerebrall\u00e4hmung Nothnagel\u2019s Specielle Pathologie und Therapie Wien Holder 1897.","journal-title":"Wien Holder"},{"key":"refR11","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1017\/S001216220500112X","volume":"47","author":"Bax M","year":"2005","unstructured":"Bax M, Goldstein M, Rosenbaum P , et al. Proposed definition and classification of cerebral palsy Dev Med Child Neurol 2005; 47 : 571-76.","journal-title":"Dev Med Child Neurol"},{"key":"refR12","unstructured":"Panteliadis CP, Ed. Cerebral palsy- A multidisciplinary approach Dustri Verlag Dr Karl Feistle M nchen-Orlando. 2011."},{"key":"refR13","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1542\/peds.64.2.225","volume":"64","author":"Nelson KB","year":"1979","unstructured":"Nelson KB, Ellenberg JH. 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Neonatal encephalopathy following fetal distress Arch Neurol 1976; 33 : 696-705.","journal-title":"Arch Neurol"},{"key":"refR43","doi-asserted-by":"crossref","first-page":"e8","DOI":"10.1111\/j.1469-8749.2010.03876.x","volume":"53","author":"Hielkema T","year":"2011","unstructured":"Hielkema T, Blauw-Hospers CH, Dirks T , et al. Does physiotherapeutic intervention affect motor outcome in high-risk infants\u03ba.An approach combining a randomized controlled trial and process evaluation Dev Med Child Neurol 2011; 53 : e8-15.","journal-title":"Dev Med Child Neurol"},{"key":"refR44","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1055\/s-0030-1262841","volume":"41","author":"Romeo DM","year":"2010","unstructured":"Romeo DM, Cioni M, diStefano A , et al. Quality of life in parents of children with cerebral palsy is it influenced by the child`s behaviour\u03ba Neuropediatrics 2010; 41 : 121-6.","journal-title":"Neuropediatrics"},{"key":"refR45","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1111\/j.1469-8749.2011.03959.x","volume":"53","author":"Darrah J","year":"2011","unstructured":"Darrah J, Law MC, Pollock N , et al. Context therapy a new intervention approach for children with cerebral palsy Dev Med Child Neurol 2011; 53 : 615-20.","journal-title":"Dev Med Child Neurol"},{"key":"refR46","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1111\/j.1469-8749.2011.04068.x","volume":"53","author":"Rosenbaum P","year":"2011","unstructured":"Rosenbaum P. Family and quality of life key elements in intervention in children with cerebral palsy Dev Med Child Neurol 2011; 53 (Suppl 4 ) : 68-70.","journal-title":"Dev Med Child Neurol"},{"key":"refR47","first-page":"327","volume":"29","author":"Fay T","year":"1948","unstructured":"Fay T. The neurophysical aspects of therapy in cerebral palsy Archiv Phys Med 1948; 29 : 327-4.","journal-title":"Archiv Phys Med"},{"key":"refR48","first-page":"1234","volume":"44","author":"Fay T","year":"1958","unstructured":"Fay T. Neuromuscular reflex therapy for spastic disorders J Fla Med Assoc 1958; 44 : 1234-40.","journal-title":"J Fla Med Assoc"},{"key":"refR49","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1001\/jama.1960.03030030037007","volume":"174","author":"Doman RJ","year":"1960","unstructured":"Doman RJ, Spitz EB, Zucman E , et al. Children with severe brain injuries.Neurological organisation in terms or mobility JAMA 1960; 174 : 257-62.","journal-title":"JAMA"},{"key":"refR50","first-page":"543","volume":"12","author":"Vojta V","year":"1965","unstructured":"Vojta V. Early diagnosis of a spastic infantile syndrome Beitr Orthop Traumatol 1965; 12 : 543-.","journal-title":"Beitr Orthop Traumatol"},{"key":"refR51","unstructured":"Scrutton D, Vojta V, Eds. The basic elements of treatments according to Vojta.Management of the motor disorders of the children with cerebral palsy Oxford Blackwell Scientific. 1984."},{"key":"refR52","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1111\/j.1469-8749.1967.tb02290.x","volume":"9","author":"Bobath B","year":"1967","unstructured":"Bobath B. The very early treatment of cerebral palsy Dev Med Child Neurol 1967; 9 : 373-90.","journal-title":"Dev Med Child Neurol"},{"key":"refR53","unstructured":"Bobath K, Bobath B, Eds. Management of the motor disorders of childrens with cerebral palsy London Mc Keith Press. 1984."},{"key":"refR54","unstructured":"Panteliadis CP, Karch D, Heinemann KJ, Blank R, Eds. Physiotherapeutic and occupational treatment of children with cerebral palsy Cerebral Palsy A multidisciplinary approach Dustri Verlag Dr Karl Feistle M nchen-Orlando. 2011; pp. 141-64."},{"key":"refR55","author":"Scrutton D","year":"2004","unstructured":"Scrutton D, Damiano D, Maystone M. Physiotherapy management in cerebral palsy an update on treatment approachs Management of the motor disorders of children with cerebral palsy Clinics in Development Machine No 161 Mc Keith Press London 2004.","journal-title":"Clinics in Development Machine No. 161 Mc Keith Press London"},{"key":"refR56","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1111\/j.1469-8749.2009.03414.x","volume":"51","author":"Orton J","year":"2009","unstructured":"Orton J, Spittle A, Doyle L , et al. 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The effects of physical therapy on cerebral palsy.A controlled trial in infants with spastic diplegia N Engl J Med 1988; 318 : 803-.","journal-title":"N Engl J Med"},{"key":"refR59","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1111\/dmcn.12246","volume":"55","author":"Novak I","year":"2013","unstructured":"Novak I, McIntyre S, Morgan C , et al. A systematic review of interventions for children with cerebral palsy state of evidence Dev Med Child Neurol 2013; 55 : 885-910.","journal-title":"Dev Med Child Neurol"},{"key":"refR60","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1469-7580.2010.01262.x","volume":"217","author":"Staudt M","year":"2010","unstructured":"Staudt M. Reorganization after pre- and perinatal brain lesions J Anat 2010; 217 : 469-74.","journal-title":"J Anat"},{"key":"refR61","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1111\/dmcn.12209","volume":"55","author":"Juenger H","year":"2013","unstructured":"Juenger H, Kuhnke N, Braun C , et al. Two types of exercise-induced neuroplasticity in congenital hemiparesis a transcranial magnetic stimulation, functional MRI, and magnetencephalographic study Dev Med Child Neurol 2013; 55 : 941-51.","journal-title":"Dev Med Child Neurol"},{"key":"refR62","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/dmcn.12273","volume":"56","author":"Eliasson AC","year":"2014","unstructured":"Eliasson AC, Krumhilde-Sundholm L, Gordon AM , et al. 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