{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T10:27:54Z","timestamp":1783074474264,"version":"3.54.6"},"reference-count":22,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T00:00:00Z","timestamp":1293753600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["opendentistryjournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TODENTJ"],"published-print":{"date-parts":[[2010,12,31]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>In Niigata prefecture, Japan, a system has been developed based on a school-based fluoride mouth rinse program as follows; students with caries susceptible teeth are screened in a school dental examination, and encouraged to receive sealant placement in local dental clinics. However, the cost-effectiveness of sealant application in the public health has been questioned. The aim of this study was to estimate of the cost-effectiveness and cost-benefit ratio for a school-based combined program with fluoride mouth rinse and targeted fissure sealant in children residing in non-fluoridated areas in Japan.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Participants:<\/jats:title>\n                    <jats:p>The analysis was based on comparing an intervention group with two cohorts in the 8-year-old (n=66) and 11-year-old (n=58) participating in the combined program for four and seven years, respectively, with a control group of the same grades (n=43 and n=54 respectively). <\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The study measured mean differences in number of decayed and filled teeth (DFT) between the study groups and a combined program cost per child during study periods. The cost-effectiveness ratio was expressed as an individual annual program cost per DFT averted. In the cost-benefit ratio the mean difference in treatment cost between groups (program benefit) was compared to program cost. <\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The mean reduced DFT differences between groups were 1.44 in 8-year-old and 3.17 in 11-year-old children. The cost-effectiveness ratio was \u00a5 493 in the 8-year-old and \u00a5 202 in the 11-year-old, respectively. The cost-benefit ratio was 1.84 in 8-year-old children and 2.42 in 11-year-old. <\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This combined program indicated acceptable cost-effectiveness and cost \u2013benefit ratio.<\/jats:p>\n                <\/jats:sec>","DOI":"10.2174\/1874210601004010230","type":"journal-article","created":{"date-parts":[[2012,3,29]],"date-time":"2012-03-29T07:29:54Z","timestamp":1333006194000},"page":"230-236","update-policy":"https:\/\/doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Economic Evaluation of a School-based Combined Program with a Targeted Pit and Fissure Sealant and Fluoride Mouth Rinse in Japan"],"prefix":"10.2174","volume":"4","author":[{"given":"Shihoko","family":"Sakuma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Yoshihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideo","family":"Miyazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seigo","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","reference":[{"key":"refR1","author":"Ahovuo-Saloranta A","year":"2004","unstructured":"Ahovuo-Saloranta A, Hiiri A, Nordblad A, Worthington H, M\u00e4kel\u00e4 M. \n                Pit and fissure sealants for preventing dental decay in the permanent teeth of children and adolescents \n                Cochrane Database of Systematic Reviews \n                2004.\n                \n             3: Art. No.: CD001830. 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\n                55\n                : 229-33.","journal-title":"J Public Health Dent"},{"key":"refR16","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1177\/154405910208100913","volume":"81","author":"Gliffin SO","year":"2002","unstructured":"Gliffin SO, Griffin PM, Gooch BF, Barker LK. \n                Comparing the costs of three sealant delivery strategies \n                J Dent Res  \n                2002; \n                81\n                : 641-5.","journal-title":"J Dent Res"},{"key":"refR17","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1111\/j.1752-7325.2005.tb02791.x","volume":"65","author":"Qui\u00f1onez RB","year":"2005","unstructured":"Qui\u00f1onez RB, Downs SM, Shugars D, Christensen J, Van WF. \n                Assessing cost-effectiveness of sealant placement in children \n                J Public Health Dent  \n                2005; \n                65\n                : 82-9.","journal-title":"J Public Health Dent"},{"key":"refR18","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1752-7325.1986.tb03127.x","volume":"46","author":"Eklund SA","year":"1986","unstructured":"Eklund SA. \n                Factors affecting the cost of fissure sealants: a dental insurer\u2019s perspective \n                J Public Health Dent  \n                1986; 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