{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T18:20:44Z","timestamp":1770834044732,"version":"3.50.1"},"reference-count":14,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2012,10,5]],"date-time":"2012-10-05T00:00:00Z","timestamp":1349395200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["opendentistryjournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TODENTJ"],"published-print":{"date-parts":[[2012,10,5]]},"abstract":"<jats:p>Pyogenic granuloma is a reactive hyperplasia of connective tissue in response to local irritants. It is a tumourlike\ngrowth of the oral cavity, frequently located surrounding the anterior teeth or skin that is considered to be neoplastic\nin nature. It usually arises in response to various stimuli such as low-grade local irritation, traumatic injury, hormonal factors,\nor certain kinds of drugs. Histologically, the surface epithelium may be intact, or may show foci of ulcerations or\neven exhibiting hyperkeratosis. It overlies a mass of dense connective tissue composed of significant amounts of mature\ncollagen. Gingiva is the most common site affected followed by buccal mucosa, tongue and lips. Pyogenic granuloma in\ngeneral, does not occur when excised along with the base and its causative factors. This paper presents some cases of a\npyogenic granuloma managed by surgical intervention.<\/jats:p>","DOI":"10.2174\/1874210601206010153","type":"journal-article","created":{"date-parts":[[2012,10,12]],"date-time":"2012-10-12T05:45:16Z","timestamp":1350020716000},"page":"153-156","update-policy":"https:\/\/doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["\u201cPyogenic Granuloma - Hyperplastic Lesion of the Gingiva: Case Reports\u201d"],"prefix":"10.2174","volume":"6","author":[{"given":"Pushpendra Kumar","family":"Verma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruchi","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HC","family":"Baranwal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TP","family":"Chaturvedi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anju","family":"Gautam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"refR1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/sj.bdj.4806194","volume":"163","author":"Macleod RI","year":"1997","unstructured":"Macleod RI, Soames JV. \n                    Epulides: a clinicopathological study of a\nseries of 200 consecutive lesions \n                    Br Dent J  \n                    1997; 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\n                    24\n                    (5\n                )\n                    : 376-82.","journal-title":"Br J Oral Maxillofac Surg"},{"key":"refR5","unstructured":"Regezi JA, Sciubba JJ, Jordon RCK. \n                    Oral pathology: clinical\npathological considerations.  4th. \n                    Philadelphia, Pa: USA: WB\nSaunders 2003."},{"key":"refR6","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/j.1879-3479.1976.tb00592.x","volume":"14","author":"Mussalli NG","year":"1976","unstructured":"Mussalli NG, Hopps RM, Johnson NW. \n                    Oral pyogenic granuloma\nas a complication of pregnancy and the use of hormonal contraceptives \n                    \nInt J Gynaecol Obstet  \n                    1976; \n                    14\n                    (2\n                )\n                    : 187-91.","journal-title":"Int J Gynaecol Obstet"},{"key":"refR7","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/S0190-9622(85)80126-2","volume":"12","author":"Miller RAW","year":"1985","unstructured":"Miller RAW, Ross JB, Martin J. \n                    Multiple granulation tissue lesions\noccurring in isotretinoin treatment of acne vulgaris: successful response\nto topical corticosteroid therapy \n                    J Am Acad Dermatol\n  \n                    1985; \n                    12 \n                    (5\n                )\n                    : 888-9.","journal-title":"J Am Acad Dermatol"},{"key":"refR8","doi-asserted-by":"crossref","first-page":"167","DOI":"10.2334\/josnusd.48.167","volume":"48","author":"Jafarzadeh H","year":"2006","unstructured":"Jafarzadeh H, Sanatkhani M, Mohtasham N. \n                    Oral pyogenic granuloma:\na review \n                    J Oral Sci  \n                    2006; \n                    48\n                    (4\n                )\n                    : 167-75.","journal-title":"J Oral Sci"},{"key":"refR9","doi-asserted-by":"crossref","first-page":"56","DOI":"10.4103\/2231-0754.95252","volume":"2","author":"Mathur LK","year":"2010","unstructured":"Mathur LK, Bhalodi AP, Manohar B, Bhatia A, Rai N, Mathur A. \n                    \nFocal fibrous hyperplasia: a case report \n                    Int J Dent Clin  \n                    2010; \n                    2\n                    (4\n                )\n                    : 56-7.","journal-title":"Int J Dent Clin"},{"key":"refR10","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/0030-4220(51)90432-X","volume":"4","author":"Kerr DA","year":"1951","unstructured":"Kerr DA. \n                    Granuloma pyogenicum \n                    Oral Surg Oral Med Oral Pathol\n  \n                    1951; \n                    4\n                    (2\n                )\n                    : 158.","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"refR11","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0266-4356(97)90561-1","volume":"35","author":"Lawoyin J","year":"1997","unstructured":"Lawoyin J, Arotiba J, Dosumu O. \n                    Oral pyogenic granuloma: a\nreview of 38 cases from Ibadan, Nigeria \n                    Br J Oral Maxillofac Surg\n  \n                    1997; \n                    35\n                    (3\n                )\n                    : 185-9.","journal-title":"Br J Oral Maxillofac Surg"},{"key":"refR12","first-page":"8","volume":"20","author":"Zain R","year":"1995","unstructured":"Zain R, Khoo S, Yeo J. \n                    Oral pyogenic granuloma clinical analysis\nof 304 cases \n                    Singapore Dent J  \n                    1995; \n                    20\n                    (1\n                )\n                    : 8-10.","journal-title":"Singapore Dent J"},{"key":"refR13","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1111\/j.1601-0825.2005.01158.x","volume":"12","author":"Parisi E","year":"2006","unstructured":"Parisi E, Glick P, Glick M. \n                    Recurrent intraoral pyogenic granuloma\nwith satellitosis treated with corticosteroids \n                    Oral Dis  \n                    2006; 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