{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T17:50:42Z","timestamp":1767894642194,"version":"3.49.0"},"reference-count":27,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2013,10,31]],"date-time":"2013-10-31T00:00:00Z","timestamp":1383177600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["opendentistryjournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TODENTJ"],"published-print":{"date-parts":[[2013,10,31]]},"abstract":"<jats:sec><jats:title>Purpose:<\/jats:title><jats:p>The aim of this study was to investigate the distribution of different types of malignant tumors in the orbital cavity, surgical treatments, and subsequent prosthetic rehabilitation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods:<\/jats:title><jats:p>A retrospective sample of 269 charts of patients attending a public reference cancer hospital in Goiania, Goias, Brazil, between 1998 and 2009 was selected. Study variables included demographic data, clinical and histopathological features, and patient rehabilitation. Frequency analysis, chi-square test and multiple logistic regression were used for data analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Patients\u2019 age ranged from 1 to 92 years and 50.2% were female. The most prevalent tumors were basal cell carcinoma (58%), retinoblastoma (17.1%), squamous cell carcinoma of the conjunctiva (7.1%), malignant melanoma (6.7%), and rhabdomyosarcoma (4.5%). Surgical treatment was performed in 250 patients (92.3%), but only 29 patients (10.8%) received ocular prosthetic rehabilitation. Lower age (p&lt;0.001) and enucleation surgery (p&lt;0.001) were significantly associated with prosthetic rehabilitation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Results revealed high occurrence of mutilating interventions and low provision of prosthetic care, limited to younger patients who had undergone enucleation surgery. The high unmet demand for rehabilitation emphasizes the need to incorporate appropriate care for ocular and orbital deformities into the Brazilian public health system.<\/jats:p><\/jats:sec>","DOI":"10.2174\/1874210601307010140","type":"journal-article","created":{"date-parts":[[2013,11,13]],"date-time":"2013-11-13T06:42:28Z","timestamp":1384324948000},"page":"140-145","update-policy":"https:\/\/doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A 12-Year Retrospective Survey of Management of Patients with Malignant Neoplasms in the Orbital Cavity in a Brazilian Cancer Hospital"],"prefix":"10.2174","volume":"7","author":[{"given":"Daniela","family":"Sirianni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e1udio Rodrigues","family":"Leles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elismauro Francisco","family":"Mendon\u00e7a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"refR1","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1590\/S0103-64402005000300013","volume":"16","author":"Coas VR","year":"2005","unstructured":"Coas VR, Neves ACC, Rode SM. Evaluation of the etiology of ocular globe atrophy or loss Braz Dent J 2005; 16 (3) : 243-6.","journal-title":"Braz Dent J"},{"key":"refR2","first-page":"122","volume":"43","author":"Gyasi ME","year":"2009","unstructured":"Gyasi ME, Amoaku WM, Adjuik M. Causes and incidence of destructive eye procedures in North-Eastern Ghana Ghana Med J 2009; 43 : 122-6.","journal-title":"Ghana Med J"},{"key":"refR3","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1136\/bjo.84.7.767","volume":"84","author":"Lee S-B","year":"2000","unstructured":"Lee S-B, Eong K-GA, Saw S-M, Chan T-K, Lee H-P. Eye cancer incidence in Singapure Br J Ophthalmol 2000; 84 : 767-0.","journal-title":"Br J Ophthalmol"},{"key":"refR4","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1136\/bjo.2005.072892","volume":"89","author":"Rahman I","year":"2005","unstructured":"Rahman I, Maino A, Cook AE, Leatherbarrow B. Mortality following exenteration for malignant tumors of the orbit Br J Ophthalmol 2005; 89 : 1445-8.","journal-title":"Br J Ophthalmol"},{"key":"refR5","first-page":"133","volume":"99","author":"Shields CL","year":"2001","unstructured":"Shields CL, Shields JA, Hosavar SG, Demirci H. Primary ophthalmic rhabdomyosarcoma in 33 patients Tr Am Ophthol Soc 2001; 99 : 133-43.","journal-title":"Tr Am Ophthol Soc"},{"key":"refR6","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1136\/bjo.2004.062471","volume":"89","author":"Rahman I","year":"2005","unstructured":"Rahman I, Cook AE, Leatherbarrow B. Orbital exenteration: a 13 year Manchester experience Br J Ophthalmol 2005; 89 : 1335-40.","journal-title":"Br J Ophthalmol"},{"key":"refR7","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1309\/MLRMQWAFV6A115UA","volume":"119","author":"Kitzmann AS","year":"2003","unstructured":"Kitzmann AS, Weaver AL, Lohse CM, Buettner H, Salom\u00e3o DR. Clinicopathologic correlations in 646 consecutive surgical eye specimens Am J Clin Pathol 2003; 119 : 594-601.","journal-title":"Am J Clin Pathol"},{"key":"refR8","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1001\/archderm.138.11.1494","volume":"138","author":"Heckmann M","year":"2002","unstructured":"Heckmann M, Zogelmeier F, Konz B. Frequency of facial basal cell carcinoma does not correlate with site-specific UV almol exposure Arch Dermatol 2002; 138 : 1494-7.","journal-title":"Arch Dermatol"},{"key":"refR9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1750-1172-1-31","volume":"1","author":"Aerts I","year":"2006","unstructured":"Aerts I, Rouic LL, Gauthier-Villars M, Brisse H, Doz F, Desjardins L. Retinoblastoma Orphanet J Rare Dis 2006; 1 (31) : 1-11.","journal-title":"Orphanet J Rare Dis"},{"key":"refR10","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1590\/S1807-59322009000500010","volume":"64","author":"Bonanoni MTBC","year":"2009","unstructured":"Bonanoni MTBC, Almeida MTA, Cristofani LM, Filho VO. Retinoblastoma: a three-year-study at a Brazilian Medical School Hospital Clinics 2009; 64 : 427-34.","journal-title":"Clinics"},{"key":"refR11","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1634\/theoncologist.12-10-1237","volume":"12","author":"Chintagumpala M","year":"2007","unstructured":"Chintagumpala M, Chevez-Barrios P, Paysse EA, Plon SE, Hurwitz R. Retinoblastoma: review of current management Oncologist 2007; 12 : 1237-46.","journal-title":"Oncologist"},{"key":"refR12","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1177\/107327480401100505","volume":"11","author":"Brownstein S","year":"2004","unstructured":"Brownstein S. Malignant melanoma of the conjunctiva Cancer Cont 2004; 11 (5) : 310-6.","journal-title":"Cancer Cont"},{"key":"refR13","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1001\/archophthalmol.2008.543","volume":"127","author":"Eagle Jr RC","year":"2009","unstructured":"Eagle Jr RC, Grossniklaus HE, Syed N, Hogan RN, Lloyd WC, Folberg R. Inadvertent evisceration of eyes containing uveal melanoma Arch Ophthalmol 2009; 127 (2) : 141-5.","journal-title":"Arch Ophthalmol"},{"key":"refR14","first-page":"471","volume":"98","author":"Shields CL","year":"2000","unstructured":"Shields CL. Conjunctival melanoma: risk factors for recurrence, exenteration, metastasis, and death in 150 consecutive patients Tr Am Ophth Soc 2000; 98 : 471-92.","journal-title":"Tr Am Ophth Soc"},{"key":"refR15","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1136\/bjo.86.10.1161","volume":"86","author":"Donaldson MJ","year":"2002","unstructured":"Donaldson MJ, Sullivan TJ, Whitehead KJ, Williamson RM. Squamous cell carcinoma of the eyelids Br J Ophthalmol 2002; 86 : 1161-5.","journal-title":"Br J Ophthalmol"},{"key":"refR16","first-page":"234","volume":"52","author":"Chaudhry TA","year":"2006","unstructured":"Chaudhry TA, Memon M, Ahmad K. Use of artificial eye and conjunctival squamous cell carcinoma J Post Med 2006; 52 : 234-5.","journal-title":"J Post Med"},{"key":"refR17","first-page":"51","volume":"18","author":"El-Aal HHA","year":"2006","unstructured":"El-Aal HHA, Habib EE, Mishrif MM. Rhabdomyosarcoma: the experience of the pediatric unit of Karsr El-Aini Center of Radiation Oncology and Nuclear Medicine (from January 1992 to January 2001) J Egypt Nat Cancer Inst 2006; 18 : 51-60.","journal-title":"J Egypt Nat Cancer Inst"},{"key":"refR18","doi-asserted-by":"crossref","first-page":"104","DOI":"10.4103\/0019-509X.38941","volume":"44","author":"Kaliaperumal S","year":"2007","unstructured":"Kaliaperumal S, Tiroumal S, Rao VA. Orbital rhabdomyosarcoma: a case series Indian J Cancer 2007; 44 (3) : 104-7.","journal-title":"Indian J Cancer"},{"key":"refR19","doi-asserted-by":"crossref","first-page":"826","DOI":"10.3129\/i07-162","volume":"42","author":"Leung AK","year":"2007","unstructured":"Leung AK, De Angelis DD, Hurwitz JJ, et al. Surgical waiting times of ocular and periocular cancer patients in Toronto Can J Ophthalmol 2007; 42 (6) : 826-31.","journal-title":"Can J Ophthalmol"},{"key":"refR20","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1590\/S1806-83242006000300012","volume":"20","author":"Mattos BSC","year":"2006","unstructured":"Mattos BSC, Montagna MC, Fernandes CS, Sab\u00f3ia ACL. The pediatric patient at a maxillofacial service \u2013 eye prosthesis Braz Oral Res 2006; 20 : 247-51.","journal-title":"Braz Oral Res"},{"key":"refR21","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1741-2358.2007.00171.x","volume":"25","author":"Patil SB","year":"2008","unstructured":"Patil SB, Meshramkar R, Naveen BH, Patil NP. Ocular prosthesis: a brief review and fabrication of an ocular prosthesis for a geriatric patient Gerodontology 2008; 25 : 57-62.","journal-title":"Gerodontology"},{"key":"refR22","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1076\/orbi.17.2.77.2764","volume":"17","author":"Rapidis AD","year":"1998","unstructured":"Rapidis AD, Liarikos S. Malignant orbital and orbitomaxillary tumors: surgical considerations Orbit 1998; 17 : 77-88.","journal-title":"Orbit"},{"key":"refR23","first-page":"565","volume":"23","author":"Seccia A","year":"1997","unstructured":"Seccia A, Salgarello M, Bracaglia R, et al. Malignant tumors of the orbital region. Analysis of cases examined from 1986 to 1995 Dermatol Surg 1997; 23 : 565-70.","journal-title":"Dermatol Surg"},{"key":"refR24","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1097\/00003226-200310000-00015","volume":"22","author":"Basti S","year":"2003","unstructured":"Basti S, Macsai MS. Ocular surface squamous neoplasia: a review Cornea 2003; 22 : 687-704.","journal-title":"Cornea"},{"key":"refR25","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1097\/00002341-200009000-00013","volume":"16","author":"Kaltreider SA","year":"2000","unstructured":"Kaltreider SA. The ideal ocular prosthesis: analysis of prosthetic volume Ophthal Plast Reconst Surg 2000; 16 : 388-92.","journal-title":"Ophthal Plast Reconst Surg"},{"key":"refR26","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1038\/sj.bjc.6605388","volume":"101","author":"Austoker J","year":"2009","unstructured":"Austoker J, Bankhead C, Forbes LJL, et al. Interventions to promote cancer awareness and early presentation: systematic review Br J of Cancer 2009; 101 : 531-9.","journal-title":"Br J of Cancer"},{"key":"refR27","author":"Costa EF","year":"2013","unstructured":"Costa EF, Nogueira TE, Lima NCS, Mendon\u00e7a EF, Leles CR. A qualitative study of the dimensions of patients\u00e2\u20ac\u2122 perceptions of facial disfigurement after head and neck cancer surgery Spec Care Dent 2013. DOI: 10.1111\/scd.12039","journal-title":"Spec Care Dent"}],"container-title":["The Open Dentistry Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/opendentistryjournal.com\/contents\/volumes\/V7\/TODENTJ-7-140\/TODENTJ-7-140.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/opendentistryjournal.com\/contents\/volumes\/V7\/TODENTJ-7-140\/TODENTJ-7-140.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/opendentistryjournal.com\/contents\/volumes\/V7\/TODENTJ-7-140\/TODENTJ-7-140.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,6]],"date-time":"2023-07-06T12:44:05Z","timestamp":1688647445000},"score":1,"resource":{"primary":{"URL":"https:\/\/opendentistryjournal.com\/VOLUME\/7\/PAGE\/140\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,31]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,10,31]]}},"alternative-id":["TODENTJ-7-140"],"URL":"https:\/\/doi.org\/10.2174\/1874210601307010140","relation":{},"ISSN":["1874-2106"],"issn-type":[{"value":"1874-2106","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10,31]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2013-8-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-9-16","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-9-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-10-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}