{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T13:15:52Z","timestamp":1789996552993,"version":"4.0.1"},"reference-count":25,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2013,3,22]],"date-time":"2013-03-22T00:00:00Z","timestamp":1363910400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["openmicrobiologyjournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TOMICROJ"],"published-print":{"date-parts":[[2013,3,22]]},"abstract":"<jats:p>\n                    <jats:italic>Brucella abortus<\/jats:italic> causes brucellosis mainly in cattle. The infection is transmitted to humans by ingestion of animal products or direct contact with infected material. While the intracellular lifestyle of <jats:italic>Brucella<\/jats:italic> is well characterized, its extracellular survival is poorly understood. In nature, bacterial persistence is associated with biofilms, where aggregated cells are protected from adversity. The inability of <jats:italic>Brucella abortus<\/jats:italic> to aggregate under aerobiosis and that fact that the replicative niche of <jats:italic>Brucella<\/jats:italic> is characterized by microaerobic conditions prompted us to investigate the capacity of this pathogen to aggregate and grow in biofilms under microaerobiotic conditions. The results show that <jats:italic>B. abortus<\/jats:italic> aggregates and produces biofilms. The aggregates tolerate desiccation better than planktonic cells do, adhere and displace even in the absence of the lipopolysaccharide-O antigen, flagella, the transcriptional regulator VjbR, or the enzymes that synthesize, transport, and modify cyclic \u03b2 (1,2) glucan.<\/jats:p>","DOI":"10.2174\/1874285801307010087","type":"journal-article","created":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T05:38:08Z","timestamp":1364794688000},"page":"87-91","update-policy":"https:\/\/doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["The Aggregation of Brucella abortus Occurs Under Microaerobic Conditions and Promotes Desiccation Tolerance and Biofilm Formation"],"prefix":"10.2174","volume":"7","author":[{"given":"Marta A","family":"Almir\u00f3n","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mara S","family":"Roset","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norberto","family":"Sanjuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"965","reference":[{"key":"refR1","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1111\/j.1462-5822.2009.01323.x","volume":"11","author":"Hall-Stoodleyl L","year":"2009","unstructured":"Hall-Stoodleyl L, Stoodley P. \n                    Evolving concepts in biofilm infections \n                    Cell Microbiol  \n                    2009; 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