{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T15:28:49Z","timestamp":1772638129790,"version":"3.50.1"},"reference-count":52,"publisher":"Bentham Science Publishers Ltd.","issue":"1","license":[{"start":{"date-parts":[[2017,4,27]],"date-time":"2017-04-27T00:00:00Z","timestamp":1493251200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"content-domain":{"domain":["openrespiratorymedicinejournal.com","benthamopen.com"],"crossmark-restriction":true},"short-container-title":["TORMJ"],"published-print":{"date-parts":[[2017,4,27]]},"abstract":"<jats:p>Throughout childhood, various developmental phenomena influence the cough reflex. Among these are the modifications in the anatomy and functions of the respiratory tract and the central and peripheral nervous systems. Moreover, after birth, the immunological response undergoes progressive transformations with the acquisition of immune memory processes. These conditions make infections and airway abnormalities the overwhelming cause of chronic cough in children and infants. In children, chronic cough should be treated on the basis of etiology. The aim of this article is to provide thorough research and analysis of the medical literature published up to 2014 on chronic cough in children as a disease entity, including the epidemiologic, etiologic, diagnostic, prognostic, and therapeutic aspects.<\/jats:p><jats:p>Our results demonstrate differences in the definition of chronic cough, the characteristics of diagnostic procedures, study settings, and prevalence of the main causes. However, few studies regarding epidemiology and the quality of life have been reported. Many therapeutic approaches that are considered effective in adults with chronic cough seem to be less efficient in children. Regardless of the setting, whether pediatric or non-pediatric, children with chronic cough should be carefully evaluated using child-specific protocols and algorithms. Awareness of the various pathophysiological conditions associated with chronic cough is vital for making a correct diagnosis and providing appropriate treatment. The prevalence of the different causes of chronic cough depends on various issues. Among these are the population under consideration and its age range, infectious disease control and prevention, the diagnostic procedures employed, disease definition criteria, and the local health system. Clinical guidelines for the management of children with chronic cough should take these components into consideration. Further clinical and basic research studies are still needed for better diagnosis, treatment, and prevention of chronic cough in children.<\/jats:p>","DOI":"10.2174\/1874306401711010001","type":"journal-article","created":{"date-parts":[[2017,4,27]],"date-time":"2017-04-27T11:24:10Z","timestamp":1493292250000},"page":"1-9","update-policy":"https:\/\/doi.org\/10.2174\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Analysis of the Literature on Chronic Cough in Children"],"prefix":"10.2174","volume":"11","author":[{"given":"Marcello","family":"Bergamini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad","family":"Kantar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renato","family":"Cutrera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Italian Pediatric Cough","family":"Interest Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"965","reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/S0034-5687(98)00076-0","volume":"114","author":"Widdicombe J.G.","year":"1998","unstructured":"Widdicombe JG. Afferent receptors in the airways and cough. Respir Physiol 1998; 114 (1) : 5-15.","journal-title":"Respir. Physiol."},{"key":"ref2","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/1745-9974-7-10","volume":"7","author":"Brooks S.M.","year":"2011","unstructured":"Brooks SM. Perspective on the human cough reflex. Cough 2011; 7 : 10.","journal-title":"Cough"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"645","DOI":"10.33549\/physiolres.930623","volume":"54","author":"Poliacek I.","year":"2005","unstructured":"Poliacek I, Str\u00e1nsky A, Szereda-Przestaszewska M, et al. Cough and laryngeal muscle discharges in brainstem lesioned anaesthetized cats. Physiol Res 2005; 54 (6) : 645-54.","journal-title":"Physiol. Res."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1242","DOI":"10.1152\/japplphysiol.00715.2002","volume":"94","author":"Morris K.F.","year":"2003","unstructured":"Morris KF, Baekey DM, Nuding SC, Dick TE, Shannon R, Lindsey BG. Invited review: Neural network plasticity in respiratory control. J Appl Physiol 2003; 94 (3) : 1242-52.","journal-title":"J. Appl. Physiol."},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"Chang AB. Causes, assessment and measurement of cough in children. In: Chung KF, Widdicombe JG, Boushey HA, Eds. Cough: causes, mechanisms and therapy. Oxford, UK: Blackwell Publishing Ltd. 2003; pp. 57-73.","DOI":"10.1002\/9780470755846.ch7"},{"key":"ref6","unstructured":"Italian Group on Evidence-Based Medicine-GIMBE Available at: http:\/\/www.gimbe.org\/ebp\/getting.html"},{"key":"ref7","first-page":"23","volume":"39","author":"Singh D.","year":"2002","unstructured":"Singh D, Arora V, Sobti PC. Chronic\/recurrent cough in rural children in Ludhiana, Punjab. Indian Pediatr 2002; 39 (1) : 23-9.","journal-title":"Indian Pediatr."},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1903","DOI":"10.1016\/j.rmed.2010.07.018","volume":"104","author":"Pan G.","year":"2010","unstructured":"Pan G, Zhang S, Feng Y, et al. Air pollution and childrens respiratory symptoms in six cities of Northern China. Respir Med 2010; 104 (12) : 1903-11.","journal-title":"Respir. Med."},{"key":"ref9","first-page":"76","volume":"18","author":"Drescher B.J.","year":"2013","unstructured":"Drescher BJ, Chang AB, Phillips N, et al. Chronic cough following acute respiratory illness in children. Respirology 2013; 18 : 76.","journal-title":"Respirology"},{"key":"ref10","first-page":"9","volume":"29","author":"Galassi C.","year":"2005","unstructured":"Galassi C, Forastiere F, Biggeri A, et al. [SIDRIA second phase: objectives, study design and methods]. Epidemiol Prev 2005; 29 (2) (Suppl.) : 9-13.","journal-title":"Epidemiol. Prev."},{"key":"ref11","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1136\/thx.2005.056986","volume":"61","author":"Marchant J.M.","year":"2006","unstructured":"Marchant JM, Masters IB, Taylor SM, Chang AB. Utility of signs and symptoms of chronic cough in predicting specific cause in children. Thorax 2006; 61 (8) : 694-8.","journal-title":"Thorax"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1819","DOI":"10.1378\/chest.13-0310","volume":"144","author":"Schmit K.M.","year":"2013","unstructured":"Schmit KM, Coeytaux RR, Goode AP, et al. Evaluating cough assessment tools: a systematic review. Chest 2013; 144 (6) : 1819-26.","journal-title":"Chest"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1136\/thx.2009.133868","volume":"65","author":"Newcombe P.A.","year":"2010","unstructured":"Newcombe PA, Sheffield JK, Juniper EF, Petsky HL, Willis C, Chang AB. Validation of a parent-proxy quality of life questionnaire for paediatric chronic cough (PC-QOL). Thorax 2010; 65 (9) : 819-23.","journal-title":"Thorax"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1016\/j.jaci.2012.10.004","volume":"131","author":"Newcombe P.A.","year":"2013","unstructured":"Newcombe PA, Sheffield JK, Chang AB. Parent cough-specific quality of life: development and validation of a short form. J Allergy Clin Immunol 2013; 131 (4) : 1069-74.","journal-title":"J. Allergy Clin. Immunol."},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1177\/014556130908801108","volume":"88","author":"Hartnick C.J.","year":"2009","unstructured":"Hartnick CJ, Zurakowski D, Haver K. Validation of a pediatric cough questionnaire. Ear Nose Throat J 2009; 88 (11) : 1213-7.","journal-title":"Ear Nose Throat J."},{"key":"ref16","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1007\/s00408-010-9272-1","volume":"189","author":"Morice A.H.","year":"2011","unstructured":"Morice AH, Faruqi S, Wright CE, Thompson R, Bland JM. Cough hypersensitivity syndrome: a distinct clinical entity. Lung 2011; 189 (1) : 73-9.","journal-title":"Lung"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1136\/thx.52.12.1081","volume":"52","author":"Cook D.G.","year":"1997","unstructured":"Cook DG, Strachan DP. Health effects of passive smoking. 3. Parental smoking and prevalence of respiratory symptoms and asthma in school age children. Thorax 1997; 52 (12) : 1081-94.","journal-title":"Thorax"},{"key":"ref18","first-page":"57","volume":"29","author":"Simoni M.","year":"2005","unstructured":"Simoni M, Lombardi E, Berti G, et al. [Effects of indoor exposures on respiratory and allergic disorders]. Epidemiol Prev 2005; 29 (2) (Suppl.) : 57-61.","journal-title":"Epidemiol. Prev."},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.1378\/chest.129.5.1132","volume":"129","author":"Marchant J.M.","year":"2006","unstructured":"Marchant JM, Masters IB, Taylor SM, Cox NC, Seymour GJ, Chang AB. Evaluation and outcome of young children with chronic cough. Chest 2006; 129 (5) : 1132-41.","journal-title":"Chest"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1378\/chest.08-0885","volume":"134","author":"Asilsoy S.","year":"2008","unstructured":"Asilsoy S, Bayram E, Agin H, et al. Evaluation of chronic cough in children. Chest 2008; 134 (6) : 1122-8.","journal-title":"Chest"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"260S","DOI":"10.1378\/chest.129.1_suppl.260S","volume":"129","author":"Chang A.B.","year":"2006","unstructured":"Chang AB, Glomb WB. Guidelines for evaluating chronic cough in pediatrics: ACCP evidence-based clinical practice guidelines. Chest 2006; 129 (1 Suppl) : 260S-83S.","journal-title":"Chest"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1378\/chest.09-0649","volume":"136","author":"Khoshoo V.","year":"2009","unstructured":"Khoshoo V, Edell D, Mohnot S, Haydel R Jr, Saturno E, Kobernick A. Associated factors in children with chronic cough. Chest 2009; 136 (3) : 811-5.","journal-title":"Chest"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"943","DOI":"10.1378\/chest.11-2725","volume":"142","author":"Chang A.B.","year":"2012","unstructured":"Chang AB, Robertson CF, Van Asperen PP, et al. A multicenter study on chronic cough in children: burden and etiologies based on a standardized management pathway. Chest 2012; 142 (4) : 943-50.","journal-title":"Chest"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1186\/1745-6215-11-103","volume":"11","author":"Chang A.B.","year":"2010","unstructured":"Chang AB, Robertson CF, van Asperen PP, et al. Can a management pathway for chronic cough in children improve clinical outcomes: protocol for a multicentre evaluation. Trials 2010; 11 : 103.","journal-title":"Trials"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"e1576","DOI":"10.1542\/peds.2012-3318","volume":"131","author":"Chang AB","year":"2013","unstructured":"Chang AB, Robertson CF, van Asperen PP, et al. A cough algorithm for chronic cough in children: a multicenter, randomized controlled study. Pediatrics 2013; 131 (5) : e1576-83.","journal-title":"Pediatrics"},{"key":"ref26","first-page":"CD006595","volume":"2","author":"Bailey E.J.","year":"2008","unstructured":"Bailey EJ, Morris PS, Kruske SG, Chang AB. Clinical pathways for chronic cough in children. Cochrane Database Syst Rev 2008; 2 (2) : CD006595.","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref27","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1136\/adc.2005.090753","volume":"92","author":"Gupta A.","year":"2007","unstructured":"Gupta A, McKean M, Chang AB. Management of chronic non-specific cough in childhood: an evidence-based review. Arch Dis Child Educ Pract Ed 2007; 92 (2) : 33-9.","journal-title":"Arch. Dis. Child. Educ. Pract. Ed."},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1827","DOI":"10.1378\/chest.13-0490","volume":"144","author":"Yancy W.S.","year":"2013","unstructured":"Yancy WS Jr, McCrory DC, Coeytaux RR, et al. Efficacy and tolerability of treatments for chronic cough: a systematic review and meta-analysis. Chest 2013; 144 (6) : 1827-38.","journal-title":"Chest"},{"key":"ref29","first-page":"CD004358","volume":"1","author":"Chang A.B.","year":"2004","unstructured":"Chang AB, McKean M, Morris P. Inhaled anti-cholinergics for prolonged non-specific cough in children. Cochrane Database Syst Rev 2004; 1 (1) : CD004358.","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref30","first-page":"CD004436","volume":"2","author":"Chang A.","year":"2004","unstructured":"Chang A, Marchant JM, McKean M, Morris P. Inhaled cromones for prolonged non-specific cough in children. Cochrane Database Syst Rev 2004; 2 (2) : CD004436.","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref31","first-page":"CD008182","volume":"4","author":"Teoh L.","year":"2011","unstructured":"Teoh L, Hurwitz M, Acworth JP, van Asperen P, Chang AB. Treatment of obstructive sleep apnoea for chronic cough in children. Cochrane Database Syst Rev 2011; 4 (4) : CD008182.","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref32","first-page":"CD005075","volume":"3","author":"Donnelly D.","year":"2006","unstructured":"Donnelly D, Everard MM, Chang AB. Indoor air modification interventions for prolonged non-specific cough in children. Cochrane Database Syst Rev 2006; 3 (3) : CD005075.","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref33","first-page":"CD007523","volume":"2","author":"Mulholland S.","year":"2009","unstructured":"Mulholland S, Chang AB. Honey and lozenges for children with non-specific cough. Cochrane Database Syst Rev 2009; 2 (2) : CD007523.","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref34","first-page":"CD005373","volume":"3","author":"Tomerak A.A.","year":"2005","unstructured":"Tomerak AA, Vyas H, Lakenpaul M, McGlashan JJ, McKean M. Inhaled beta2-agonists for treating non-specific chronic cough in children. Cochrane Database Syst Rev 2005; 3 (3) : CD005373.","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref35","first-page":"CD005602","volume":"2","author":"Chang A.B.","year":"2006","unstructured":"Chang AB, Winter D, Acworth JP. Leukotriene receptor antagonist for prolonged non-specific cough in children. Cochrane Database Syst Rev 2006; 2 (2) : CD005602.","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref36","first-page":"CD005310","volume":"3","author":"Chang A.B.","year":"2005","unstructured":"Chang AB, Halstead RA, Petsky HL. Methylxanthines for prolonged non-specific cough in children. Cochrane Database Syst Rev 2005; 3 (3) : CD005310.","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref37","first-page":"CD009834","volume":"12","author":"McCallum G.B.","year":"2012","unstructured":"McCallum GB, Morris PS, Chang AB. Antibiotics for persistent cough or wheeze following acute bronchiolitis in children. Cochrane Database Syst Rev 2012; 12 : CD009834.","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref38","first-page":"CD005604","volume":"2","author":"Chang A.B.","year":"2008","unstructured":"Chang AB, Peake J, McElrea MS. Anti-histamines for prolonged non-specific cough in children. Cochrane Database Syst Rev 2008; 2 (2) : CD005604.","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref39","first-page":"CD004231","volume":"4","author":"Tomerak A.A.","year":"2005","unstructured":"Tomerak AA, McGlashan JJ, Vyas HH, McKean MC. Inhaled corticosteroids for non-specific chronic cough in children. Cochrane Database Syst Rev 2005; 4 (4) : CD004231.","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref40","first-page":"CD008888","volume":"2","author":"Anderson-James S.","year":"2013","unstructured":"Anderson-James S, Marchant JM, Acworth JP, Turner C, Chang AB. Inhaled corticosteroids for subacute cough in children. Cochrane Database Syst Rev 2013; 2 (2) : CD008888.","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref41","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1136\/adc.81.1.38","volume":"81","author":"Davies M.J.","year":"1999","unstructured":"Davies MJ, Fuller P, Picciotto A, McKenzie SA. Persistent nocturnal cough: randomised controlled trial of high dose inhaled corticosteroid. Arch Dis Child 1999; 81 (1) : 38-44.","journal-title":"Arch. Dis. Child."},{"key":"ref42","first-page":"CD004823","volume":"1","author":"Chang A.B.","year":"2011","unstructured":"Chang AB, Lasserson TJ, Gaffney J, Connor FL, Garske LA. Gastro-oesophageal reflux treatment for prolonged non-specific cough in children and adults. Cochrane Database Syst Rev 2011; 1 (1) : CD004823.","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref43","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1016\/j.jpeds.2008.09.054","volume":"154","author":"Orenstein S.R.","year":"2009","unstructured":"Orenstein SR, Hassall E, Furmaga-Jablonska W, Atkinson S, Raanan M. Multicenter, double-blind, randomized, placebo-controlled trial assessing the efficacy and safety of proton pump inhibitor lansoprazole in infants with symptoms of gastroesophageal reflux disease. J Pediatr 2009; 154 (4) : 514-520.e4.","journal-title":"J. Pediatr."},{"key":"ref44","first-page":"321","volume":"14","author":"Adamko D.J.","year":"2012","unstructured":"Adamko DJ, Majaesic CM, Skappak C, Jones AB. A pilot trial on the treatment of gastroesophageal reflux-related cough in infants. Zhongguo Dang Dai Er Ke Za Zhi 2012; 14 (5) : 321-7.","journal-title":"Zhongguo Dang Dai Er Ke Za Zhi"},{"key":"ref45","first-page":"CD004822","volume":"4","author":"Marchant J.M.","year":"2005","unstructured":"Marchant JM, Morris P, Gaffney JT, Chang AB. Antibiotics for prolonged moist cough in children. Cochrane Database Syst Rev 2005; 4 (4) : CD004822.","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref46","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1136\/thoraxjnl-2011-201506","volume":"67","author":"Marchant J.","year":"2012","unstructured":"Marchant J, Masters IB, Champion A, Petsky H, Chang AB. Randomised controlled trial of amoxycillin clavulanate in children with chronic wet cough. Thorax 2012; 67 (8) : 689-93.","journal-title":"Thorax"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"206","DOI":"10.3132\/pcrj.2008.00028","volume":"17","author":"Leconte S.","year":"2008","unstructured":"Leconte S, Paulus D, Degryse J. Prolonged cough in children: a summary of the Belgian primary care clinical guideline. Prim Care Respir J 2008; 17 (4) : 206-11.","journal-title":"Prim. Care Respir. J."},{"key":"ref48","first-page":"iii1","volume":"63","author":"Shields M.D.","year":"2008","unstructured":"Shields MD, Bush A, Everard ML, McKenzie S, Primhak R. BTS guidelines: Recommendations for the assessment and management of cough in children. Thorax 2008; 63 (Suppl. 3) : iii1-iii15.","journal-title":"Thorax"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"265","DOI":"10.5694\/j.1326-5377.2010.tb03504.x","volume":"192","author":"Gibson P.G.","year":"2010","unstructured":"Gibson PG, Chang AB, Glasgow NJ, et al. CICADA: Cough in Children and Adults: Diagnosis and Assessment. Australian cough guidelines summary statement. Med J Aust 2010; 192 (5) : 265-71.","journal-title":"Med. J. Aust."},{"key":"ref50","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1378\/chest.14-1485","volume":"146","author":"Irwin R.S.","year":"2014","unstructured":"Irwin RS, French CT, Lewis SZ, Diekemper RL, Gold PM. Overview of the management of cough. Chest 2014; 146 (4) : 885-9.","journal-title":"Chest"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"S33","DOI":"10.1007\/s00408-009-9166-2","volume":"188","author":"Chang A.B.","year":"2010","unstructured":"Chang AB. Pediatric cough: children are not miniature adults. Lung 2010; 188 (Suppl. 1) : S33-40.","journal-title":"Lung"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"S19","DOI":"10.1016\/j.earlhumdev.2013.07.018","volume":"89","author":"Kantar A.","year":"2013","unstructured":"Kantar A, Bernardini R, Paravati F, Minasi D, Sacco O. Chronic cough in preschool children. Early Hum Dev 2013; 89 (Suppl. 3) : S19-24.","journal-title":"Early Hum. Dev."}],"container-title":["The Open Respiratory Medicine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/openrespiratorymedicinejournal.com\/contents\/volumes\/V11\/TORMJ-11-1\/TORMJ-11-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/openrespiratorymedicinejournal.com\/contents\/volumes\/V11\/TORMJ-11-1\/TORMJ-11-1.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/openrespiratorymedicinejournal.com\/contents\/volumes\/V11\/TORMJ-11-1\/TORMJ-11-1.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,23]],"date-time":"2024-06-23T20:24:05Z","timestamp":1719174245000},"score":1,"resource":{"primary":{"URL":"https:\/\/openrespiratorymedicinejournal.com\/VOLUME\/11\/PAGE\/1\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,27]]},"references-count":52,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,4,27]]}},"alternative-id":["TORMJ-11-1"],"URL":"https:\/\/doi.org\/10.2174\/1874306401711010001","relation":{},"ISSN":["1874-3064"],"issn-type":[{"value":"1874-3064","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4,27]]},"assertion":[{"value":"Peer Reviewed","order":0,"name":"review_status","label":"Review Status","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review Process","group":{"name":"peer_review_details","label":"Peer Review Details"}},{"value":"Checked with iThenticate","order":0,"name":"screening_status","label":"Screening Status","group":{"name":"plagiarism_screening","label":"Plagiarism Screening"}},{"value":"2017-01-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-03-06","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-03-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-04-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}